The LabelHash Server

Top 150 matches

For each match you can click on the "[pdb]" link to download a PDB file with the matching chain aligned with the motif.
Download a zip file with PDB files for all the matches and the motif itself.

PDB ID		LRMSD / p-value	Matching Residues	EC	Gene Ontology annotations
PDB ID		LRMSD / p-value	Matching Residues	EC	Biological Process	Cellular Component	Molecular Function
1kh9B alkaline phosphatase	[pdb]	0.0764 1.66e-05	51^ASP 101^ASP 102^SER 166^ARG 331^HIS 412^HIS	3.1.3.1	metabolic process dephosphorylation	periplasmic space	magnesium ion binding catalytic activity alkaline phosphatase activity protein binding zinc ion binding hydrolase activity phosphatase activity oxidoreductase activity acting on phosphorus or arsenic in donors hydrogenase (acceptor) activity
1k7hB alkaline phosphatase	[pdb]	0.231 7.58e-05	37^ASP 85^ASP 86^SER 162^ARG 319^HIS 432^HIS	0.0.0.0	metabolic process		catalytic activity alkaline phosphatase activity hydrolase activity phosphatase activity
3a52A cold-active alkaline phosphatase	[pdb]	0.256 9.73e-05	9^ASP 57^ASP 58^SER 122^ARG 231^HIS 362^HIS	0.0.0.0	metabolic process		catalytic activity phosphatase activity
2x98A alkaline phosphatase	[pdb]	0.289 0.000121	56^ASP 114^ASP 115^SER 183^ARG 308^HIS 435^HIS	0.0.0.0	metabolic process		catalytic activity alkaline phosphatase activity hydrolase activity phosphatase activity
3e2dB alkaline phosphatase	[pdb]	0.297 0.000126	12^ASP 64^ASP 65^SER 129^ARG 277^HIS 465^HIS	0.0.0.0	carbohydrate metabolic process metabolic process		catalytic activity phosphatase activity
2r3sB uncharacterized protein	[pdb]	1.02 0.000235	292^ALA 298^ASP 287^SER 277^ARG 119^GLY 296^ASN
2vvmA monoamine oxidase n	[pdb]	1.07 0.000306	468^ASP 458^ASP 465^SER 336^SER 48^GLY 456^ASN	1.4.3.4	oxidation-reduction process	peroxisome	primary amine oxidase activity oxidoreductase activity
3h7tB group 3 allergen smipp-s yvt004a06	[pdb]	1.08 0.000306	190^ALA 141^GLU 123^SER 136^SER 173^GLY 143^ASN	0.0.0.0	proteolysis		catalytic activity serine-type endopeptidase activity
1uynX nalp	[pdb]	1.11 0.000392	861^ALA 810^ASP 809^SER 803^ARG 1081^GLY 814^HIS	0.0.0.0	proteolysis	outer membrane	serine-type endopeptidase activity
2j5gE alr4455 protein	[pdb]	1.11 0.000392	141^ASP 123^GLU 122^SER 112^SER 168^GLY 156^HIS	0.0.0.0	metabolic process		catalytic activity
3lfiA fructosyltransferase	[pdb]	1.12 0.000412	119^ASP 113^ASP 137^SER 153^SER 81^GLY 107^GLN	0.0.0.0	carbohydrate metabolic process metabolic process		hydrolase activity hydrolyzing O-glycosyl compounds hydrolase activity
1xzwB purple acid phosphatase	[pdb]	1.13 0.000456	640^ASP 865^GLU 864^SER 669^ARG 633^GLY 824^HIS	3.1.3.2		extracellular region	acid phosphatase activity hydrolase activity metal ion binding
2vigF short-chain specific acyl-coa dehydrogenase,	[pdb]	1.14 0.00048	352^ALA 103^GLU 277^SER 117^SER 381^HIS 284^GLN	1.3.99.2	lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation metabolic process response to starvation response to glucocorticoid stimulus oxidation-reduction process	mitochondrion mitochondrial matrix	fatty-acyl-CoA binding acyl-CoA dehydrogenase activity butyryl-CoA dehydrogenase activity oxidoreductase activity oxidoreductase activity acting on the CH-CH group of donors
1b3oA protein (inosine monophosphate dehydrogenase 2)	[pdb]	1.16 0.000563	473^ALA 50^ASP 475^SER 53^SER 466^HIS 48^GLN	1.1.1.205	purine nucleotide biosynthetic process GMP biosynthetic process metabolic process purine ribonucleoside monophosphate biosynthetic process lymphocyte proliferation oxidation-reduction process	cytosol	catalytic activity IMP dehydrogenase activity protein binding oxidoreductase activity metal ion binding
3opyD 6-phosphofructo-1-kinase gamma-subunit 6-phosphofructo-1-kinase alpha-subunit 6-phosphofructo-1-kinase beta-subunit	[pdb]	1.16 0.000563	345^GLN 192^LYS 193^ILE 189^GLY 376^GLY 468^GLN	0.0.0.0	glycolysis glycolysis	cytoplasm 6-phosphofructokinase complex cytoplasm 6-phosphofructokinase complex	6-phosphofructokinase activity kinase activity transferase activity nucleotide binding 6-phosphofructokinase activity ATP binding kinase activity transferase activity nucleotide binding 6-phosphofructokinase activity ATP binding kinase activity transferase activity
1xfdD dipeptidyl aminopeptidase-like protein 6	[pdb]	1.16 0.000595	316^ALA 290^ASP 289^SER 214^SER 279^GLY 319^ASN	0.0.0.0	proteolysis cell death	membrane integral to membrane	dipeptidyl-peptidase activity
2datA possible global transcription activator snf2l2	[pdb]	1.17 0.000595	91^ALA 104^ASP 105^SER 110^SER 98^GLY 100^GLN	0.0.0.0	chromatin remodeling regulation of transcription DNA-dependent regulation of transcription from RNA polymerase II promoter nervous system development negative regulation of cell proliferation positive regulation of gene-specific transcription from RNA polymerase II promoter	nucleus nucleoplasm SWI/SNF complex SWI/SNF-type complex npBAF complex nBAF complex	nucleotide binding nucleic acid binding DNA binding transcription coactivator activity helicase activity protein binding ATP binding DNA-dependent ATPase activity transcription activator activity hydrolase activity hydrolase activity
1jg9A amylosucrase	[pdb]	1.19 0.000739	511^ALA 394^ASP 448^SER 445^CYS 145^GLY 392^HIS	2.4.1.4	carbohydrate metabolic process	extracellular region	catalytic activity transferase activity transferase activity transferring glycosyl groups cation binding
1f7tA holo-(acyl carrier protein) synthase	[pdb]	1.2 0.00074	63^ALA 58^GLU 61^SER 73^SER 100^HIS 113^GLN	2.7.8.7	fatty acid biosynthetic process lipid biosynthetic process macromolecule biosynthetic process	cytoplasm	magnesium ion binding holo-[acyl-carrier-protein] synthase activity transferase activity metal ion binding
1zcoB 2-dehydro-3-deoxyphosphoheptonate aldolase	[pdb]	1.21 0.000824	235^ALA 238^ASP 237^SER 62^ARG 29^GLY 242^GLN	0.0.0.0	metabolic process biosynthetic process aromatic amino acid family biosynthetic process		catalytic activity 3-deoxy-7-phosphoheptulonate synthase activity transferase activity aldehyde-lyase activity
2zxqA endo-alpha-n-acetylgalactosaminidase	[pdb]	1.22 0.000915	728^ALA 682^ASP 683^SER 1297^ARG 756^GLY 720^ASN	0.0.0.0	cell adhesion metabolic process		carboxypeptidase activity hydrolase activity hydrolase activity acting on glycosyl bonds carbohydrate binding
1vs1D 3-deoxy-7-phosphoheptulonate synthase	[pdb]	1.22 0.000915	250^ALA 253^ASP 252^SER 77^ARG 44^GLY 257^GLN	0.0.0.0	metabolic process biosynthetic process aromatic amino acid family biosynthetic process		catalytic activity 3-deoxy-7-phosphoheptulonate synthase activity transferase activity aldehyde-lyase activity
1j32B aspartate aminotransferase	[pdb]	1.23 0.000964	22^ALA 341^GLU 340^SER 335^SER 376^GLY 346^HIS	0.0.0.0	biosynthetic process		catalytic activity L-aspartate:2-oxoglutarate aminotransferase activity transaminase activity transferase activity transferase activity transferring nitrogenous groups 1-aminocyclopropane-1-carboxylate synthase activity
1ii2B phosphoenolpyruvate carboxykinase	[pdb]	1.23 0.000964	208^ALA 233^ASP 231^SER 435^ARG 214^GLY 237^ASN	0.0.0.0	gluconeogenesis	peroxisome glycosome	nucleotide binding phosphoenolpyruvate carboxykinase activity phosphoenolpyruvate carboxykinase (ATP) activity ATP binding lyase activity carboxy-lyase activity purine nucleotide binding
2rkbA serine dehydratase-like	[pdb]	1.23 0.000964	78^ALA 39^GLU 46^SER 276^CYS 150^GLY 15^HIS	0.0.0.0	cellular amino acid metabolic process metabolic process biological adhesion	cellular_component mitochondrion	molecular_function catalytic activity L-serine ammonia-lyase activity L-threonine ammonia-lyase activity lyase activity pyridoxal phosphate binding
3czdA glutaminase kidney isoform	[pdb]	1.24 0.00102	480^ALA 467^ASP 469^SER 314^SER 483^GLY 510^ASN	3.5.1.2	glutamine metabolic process glutamine catabolic process	mitochondrion	glutaminase activity hydrolase activity
2nsmA carboxypeptidase n catalytic chain	[pdb]	1.24 0.00102	371^ALA 355^ASP 350^SER 358^ARG 394^HIS 333^ASN	3.4.17.3	proteolysis response to glucocorticoid stimulus	extracellular region extracellular space	carboxypeptidase activity metallocarboxypeptidase activity peptidase activity metallopeptidase activity zinc ion binding hydrolase activity metal ion binding
3eglC degv family protein	[pdb]	1.24 0.00107	241^ASP 8^ASP 10^SER 69^SER 29^HIS 27^ASN
3hykA holo-[acyl-carrier-protein] synthase	[pdb]	1.25 0.00113	63^ALA 58^GLU 61^SER 73^SER 98^HIS 111^GLN	2.7.8.7	fatty acid biosynthetic process lipid biosynthetic process macromolecule biosynthetic process	cytoplasm	magnesium ion binding holo-[acyl-carrier-protein] synthase activity transferase activity metal ion binding
1yggA phosphoenolpyruvate carboxykinase	[pdb]	1.25 0.00113	235^ALA 260^ASP 258^SER 456^ARG 241^GLY 264^GLN	0.0.0.0	gluconeogenesis gluconeogenesis	cytoplasm cytoplasm	phosphoenolpyruvate carboxykinase activity phosphoenolpyruvate carboxykinase (ATP) activity ATP binding kinase activity lyase activity purine nucleotide binding nucleotide binding phosphoenolpyruvate carboxykinase activity phosphoenolpyruvate carboxykinase (ATP) activity ATP binding lyase activity carboxy-lyase activity purine nucleotide binding
2kvpA talin-1	[pdb]	1.25 0.00113	1861^ALA 1959^GLU 1958^SER 1953^CYS 1918^HIS 1963^HIS	0.0.0.0	cytoskeletal anchoring at plasma membrane cell-substrate junction assembly cell adhesion cortical actin cytoskeleton organization	ruffle cytoplasm centrosome cytoskeleton plasma membrane focal adhesion actin cytoskeleton membrane ruffle membrane cell projection intracellular membrane-bounded organelle	actin binding insulin receptor binding structural molecule activity structural constituent of cytoskeleton binding protein binding vinculin binding LIM domain binding
3i5tA aminotransferase	[pdb]	1.26 0.00119	127^ALA 225^GLU 257^SER 273^SER 120^GLY 154^HIS	0.0.0.0			catalytic activity transaminase activity transferase activity pyridoxal phosphate binding
3husC fibrinogen beta chain fibrinogen gamma chain fibrinogen alpha chain peptide ligand gly-pro-arg-pro-amide	[pdb]	1.26 0.00126	161^ALA 183^GLU 164^SER 219^SER 150^GLY 154^GLN	0.0.0.0	signal transduction blood coagulation platelet activation protein polymerization response to calcium ion signal transduction blood coagulation platelet activation protein polymerization response to calcium ion signal transduction blood coagulation platelet activation protein polymerization response to calcium ion	extracellular region fibrinogen complex extracellular space plasma membrane external side of plasma membrane platelet alpha granule platelet alpha granule lumen extracellular region fibrinogen complex extracellular space plasma membrane external side of plasma membrane platelet alpha granule platelet alpha granule lumen extracellular region fibrinogen complex extracellular space soluble fraction plasma membrane cell cortex external side of plasma membrane platelet alpha granule platelet alpha granule lumen	receptor binding protein binding protein binding bridging eukaryotic cell surface binding receptor binding protein binding bridging eukaryotic cell surface binding receptor binding protein binding protein binding
1ivyB human protective protein	[pdb]	1.27 0.00126	374^ALA 149^GLU 150^SER 62^SER 428^GLY 368^ASN	3.4.16.5	proteolysis intracellular protein transport	mitochondrion lysosome endoplasmic reticulum	carboxypeptidase activity serine-type carboxypeptidase activity protein binding enzyme activator activity peptidase activity hydrolase activity
2gp6A 3-oxoacyl-[acyl-carrier-protein] synthase 2	[pdb]	1.28 0.00139	169^ALA 175^GLU 172^SER 194^CYS 311^HIS 409^ASN	2.3.1.41	response to hypoxia fatty acid biosynthetic process metabolic process lipid biosynthetic process biosynthetic process fatty acid elongation growth Actinobacterium-type cell wall biogenesis mycolic acid biosynthetic process	cell wall cytoplasm plasma membrane	catalytic activity 3-oxoacyl-[acyl-carrier-protein] synthase activity protein binding acyltransferase activity transferase activity
3qt9A putative uncharacterized protein cpe0426	[pdb]	1.29 0.00147	300^ASP 220^ASP 219^SER 64^ARG 394^GLY 350^HIS				catalytic activity
1p5jA l-serine dehydratase	[pdb]	1.29 0.00147	71^ALA 32^ASP 39^SER 270^CYS 144^GLY 8^HIS	4.3.1.17	gluconeogenesis cellular amino acid metabolic process L-serine catabolic process metabolic process response to nutrient levels response to cobalamin pyruvate biosynthetic process response to amino acid stimulus	cellular_component cytoplasm	catalytic activity L-serine ammonia-lyase activity L-threonine ammonia-lyase activity lyase activity pyridoxal phosphate binding protein homodimerization activity protein dimerization activity
3pzlA agmatine ureohydrolase	[pdb]	1.29 0.00147	144^ASP 148^ASP 147^SER 185^SER 242^GLY 124^HIS	0.0.0.0	polyamine biosynthetic process		agmatinase activity hydrolase activity hydrolase activity acting on carbon-nitrogen (but not peptide) bonds
2gbpA d-galactose/d-glucose binding protein	[pdb]	1.3 0.00163	155^ALA 114^GLU 112^SER 292^ARG 234^GLY 119^GLN	0.0.0.0	transport chemotaxis carbohydrate transport transport chemotaxis carbohydrate transport transport chemotaxis carbohydrate transport	periplasmic space periplasmic space periplasmic space
3nvtA 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase	[pdb]	1.3 0.00163	330^ALA 333^ASP 332^SER 157^ARG 124^GLY 337^GLN	0.0.0.0	metabolic process biosynthetic process aromatic amino acid family biosynthetic process chorismate metabolic process		catalytic activity aldehyde-lyase activity
1gcaA glucose/galactose-binding protein	[pdb]	1.3 0.00163	155^ALA 114^GLU 112^SER 292^ARG 234^GLY 119^GLN	0.0.0.0	transport chemotaxis carbohydrate transport	periplasmic space
3bd0A protein memo1	[pdb]	1.3 0.00163	13^ALA 128^GLU 11^SER 7^CYS 136^HIS 131^HIS	0.0.0.0		nucleus cytosol
3bz6A upf0502 protein pspto_2686	[pdb]	1.31 0.00172	137^ASP 124^GLU 123^SER 167^ARG 133^HIS 130^ASN	0.0.0.0
1nhcF polygalacturonase i	[pdb]	1.31 0.00172	318^ASP 251^ASP 250^SER 219^SER 260^GLY 282^GLN	3.2.1.15	carbohydrate metabolic process cellular cell wall organization metabolic process	extracellular region	polygalacturonase activity hydrolase activity hydrolase activity
3igfA all4481 protein	[pdb]	1.31 0.00181	115^ALA 108^ASP 109^SER 140^ARG 37^GLY 68^GLN
3pcqL photosystem i 4.8k protein photosystem i reaction center subunit xi photosystem i reaction center subunit viii photosystem i reaction center subunit iv photosystem i p700 chlorophyll a apoprotein a1 photosystem i p700 chlorophyll a apoprotein a2 photosystem i reaction center subunit xii photosystem i reaction center subunit iii photosystem i reaction center subunit psak photosystem i reaction center subunit ix photosystem i reaction center subunit ii photosystem i iron-sulfur center	[pdb]	1.31 0.00181	94^ALA 115^GLU 114^SER 106^SER 47^GLY 119^GLN		photosynthesis photosynthesis transport photosynthesis protein-chromophore linkage electron transport chain transport photosynthesis protein-chromophore linkage electron transport chain transport photosynthetic electron transport in photosystem I photosynthesis electron transport chain photosynthesis photosynthesis photosynthesis photosynthesis photosynthesis photosynthesis	photosystem I photosystem I reaction center photosystem I thylakoid membrane integral to membrane plasma membrane-derived photosystem I thylakoid membrane photosystem I thylakoid membrane integral to membrane thylakoid membrane photosystem I thylakoid membrane integral to membrane thylakoid membrane photosystem I thylakoid membrane thylakoid membrane photosystem I photosystem I reaction center photosystem I plastid photosystem I reaction center thylakoid membrane thylakoid membrane photosystem I thylakoid membrane integral to membrane thylakoid membrane photosystem I thylakoid membrane integral to membrane thylakoid membrane photosystem I thylakoid membrane integral to membrane thylakoid membrane photosystem I photosystem I reaction center thylakoid membrane integral to membrane thylakoid membrane	chlorophyll binding metal ion binding iron-sulfur cluster binding 4 iron 4 sulfur cluster binding chlorophyll binding metal ion binding iron-sulfur cluster binding 4 iron 4 sulfur cluster binding electron carrier activity metal ion binding iron-sulfur cluster binding
1xwyA deoxyribonuclease tatd	[pdb]	1.31 0.00181	109^ALA 65^ASP 66^SER 98^ARG 90^GLY 38^ASN	0.0.0.0	misfolded or incompletely synthesized protein catabolic process	cytoplasm	nuclease activity deoxyribonuclease activity hydrolase activity endodeoxyribonuclease activity producing 5'-phosphomonoesters
2qvpB uncharacterized protein	[pdb]	1.31 0.00181	225^ASP 229^GLU 230^SER 235^SER 128^GLY 126^ASN	0.0.0.0	metabolic process		hydrolase activity
3cp9B vascular endothelial growth factor receptor 2	[pdb]	1.31 0.00181	1030^ALA 1087^ASP 1090^SER 1142^CYS 1015^GLY 1026^HIS		angiogenesis ovarian follicle development vasculogenesis positive regulation of endothelial cell proliferation positive regulation of mesenchymal cell proliferation protein phosphorylation transmembrane receptor protein tyrosine kinase signaling pathway multicellular organismal development positive regulation of cell proliferation regulation of cell shape positive regulation of endothelial cell migration cell migration hemopoiesis cell differentiation lung development positive regulation of cell migration surfactant homeostasis interspecies interaction between organisms cell fate commitment endothelial cell differentiation vascular endothelial growth factor receptor signaling pathway lung alveolus development cell maturation branching morphogenesis of a tube positive regulation of epithelial cell proliferation positive regulation of positive chemotaxis positive regulation of focal adhesion assembly calcium ion homeostasis	integral to plasma membrane membrane integral to membrane	nucleotide binding protein kinase activity protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity receptor signaling protein tyrosine kinase activity receptor activity vascular endothelial growth factor receptor activity integrin binding protein binding ATP binding kinase activity transferase activity growth factor binding Hsp90 protein binding
1gq7D proclavaminate amidino hydrolase	[pdb]	1.31 0.00181	144^ASP 148^ASP 147^SER 192^SER 248^GLY 121^HIS	3.5.3.22	polyamine biosynthetic process		agmatinase activity hydrolase activity hydrolase activity acting on carbon-nitrogen (but not peptide) bonds in linear amidines
2rb7A peptidase, m20/m25/m40 family	[pdb]	1.32 0.0019	31^ALA 74^ASP 19^SER 22^SER 145^GLY 72^HIS	0.0.0.0	proteolysis metabolic process		protein binding metallopeptidase activity hydrolase activity
3ef2A agglutinin	[pdb]	1.33 0.00209	183^ASP 162^GLU 159^SER 155^ARG 244^GLY 164^GLN	0.0.0.0
1wnfA l-asparaginase	[pdb]	1.33 0.00209	294^ALA 164^GLU 153^SER 156^ARG 267^GLY 167^ASN	0.0.0.0	cellular amino acid metabolic process		asparaginase activity
9gacA protein (glycosylasparaginase)	[pdb]	1.34 0.00209	157^ALA 71^ASP 165^SER 68^CYS 198^GLY 195^ASN	3.5.1.26		periplasmic space	N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity hydrolase activity
1snuB tyrosine-protein kinase itk/tsk	[pdb]	1.34 0.00209	484^ALA 540^ASP 543^SER 594^CYS 469^GLY 480^HIS	2.7.10.2	protein phosphorylation cellular defense response signal transduction	cytosol plasma membrane membrane	nucleotide binding protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein binding ATP binding kinase activity transferase activity metal ion binding
2wgfF 3-oxoacyl-[acyl-carrier-protein] synthase 1	[pdb]	1.34 0.00209	170^ALA 176^GLU 173^SER 195^CYS 311^HIS 408^ASN	2.3.1.41	fatty acid biosynthetic process metabolic process lipid biosynthetic process biosynthetic process fatty acid elongation saturated fatty acid fatty acid elongation	cell wall cytoplasm cytosol plasma membrane fatty acid elongase complex	catalytic activity 3-oxoacyl-[acyl-carrier-protein] synthase activity protein binding acyltransferase activity transferase activity
1mqbA ephrin type-a receptor 2	[pdb]	1.34 0.0022	741^ALA 799^ASP 802^SER 853^CYS 726^GLY 737^HIS	2.7.10.1	skeletal system development angiogenesis blood vessel development vasculogenesis protein phosphorylation apoptosis signal transduction transmembrane receptor protein tyrosine kinase signaling pathway multicellular organismal development notochord formation neural tube development neuron differentiation tail morphogenesis regulation of blood vessel endothelial cell migration regulation of angiogenesis ephrin receptor signaling pathway axial mesoderm formation notochord morphogenesis notochord cell development	plasma membrane integral to plasma membrane membrane integral to membrane	nucleotide binding protein kinase activity protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity receptor activity ephrin receptor activity protein binding ATP binding kinase activity transferase activity
2x5fA aspartate_tyrosine_phenylalanine pyridoxal-5'phosphate-dependent aminotransferase	[pdb]	1.34 0.0022	109^ASP 105^GLU 107^SER 101^ARG 284^GLY 253^ASN	0.0.0.0	biosynthetic process		catalytic activity transferase activity transferring nitrogenous groups
3pfeA succinyl-diaminopimelate desuccinylase	[pdb]	1.35 0.0023	37^ASP 98^ASP 33^SER 166^SER 44^GLY 31^ASN		metabolic process		protein binding hydrolase activity
1pwhB l-serine dehydratase	[pdb]	1.35 0.0023	71^ALA 32^ASP 39^SER 270^CYS 144^GLY 8^HIS	4.3.1.17, 4.3.1.19	gluconeogenesis cellular amino acid metabolic process L-serine catabolic process metabolic process response to nutrient levels response to cobalamin pyruvate biosynthetic process response to amino acid stimulus	cytoplasm	catalytic activity L-serine ammonia-lyase activity L-threonine ammonia-lyase activity lyase activity pyridoxal phosphate binding protein homodimerization activity protein dimerization activity
3hfwA protein adp-ribosylarginine hydrolase	[pdb]	1.35 0.0023	278^ALA 302^ASP 305^SER 54^SER 294^HIS 299^HIS	3.2.2.19	protein modification process protein de-ADP-ribosylation		magnesium ion binding ADP-ribosylarginine hydrolase activity hydrolase activity
3ifeA peptidase t	[pdb]	1.36 0.00242	16^ASP 175^ASP 19^SER 23^SER 36^GLY 79^HIS	3.4.11.4	proteolysis peptide metabolic process metabolic process	cytoplasm	aminopeptidase activity protein binding peptidase activity metallopeptidase activity zinc ion binding hydrolase activity tripeptide aminopeptidase activity metal ion binding
3pflB protein (formate acetyltransferase 1)	[pdb]	1.36 0.00242	415^ALA 661^ASP 421^SER 664^SER 175^GLY 430^GLN	2.3.1.54	carbohydrate metabolic process glucose metabolic process metabolic process	cytoplasm membrane	catalytic activity protein binding acyltransferase activity formate C-acetyltransferase activity transferase activity
3mosA transketolase	[pdb]	1.36 0.00253	337^ALA 349^GLU 348^SER 318^ARG 329^GLY 355^HIS	2.2.1.1	metabolic process	cytosol	catalytic activity transketolase activity protein binding transferase activity metal ion binding
1qibA protein (gelatinase a)	[pdb]	1.37 0.00253	165^ALA 177^ASP 178^SER 100^ARG 201^HIS 205^HIS	3.4.24.24	angiogenesis response to hypoxia blood vessel maturation intramembranous ossification proteolysis metabolic process collagen catabolic process skeletal system morphogenesis face morphogenesis bone trabecula formation	extracellular region proteinaceous extracellular matrix extracellular space nucleus plasma membrane membrane sarcomere extracellular matrix intracellular membrane-bounded organelle	metalloendopeptidase activity protein binding peptidase activity metallopeptidase activity zinc ion binding hydrolase activity metal ion binding
2ch1C 3-hydroxykynurenine transaminase	[pdb]	1.37 0.00253	127^ASP 153^ASP 156^SER 356^ARG 312^HIS 160^GLN	0.0.0.0	metabolic process		catalytic activity pyridoxal phosphate binding
1ggqC outer surface protein c	[pdb]	1.37 0.00253	187^ALA 51^ASP 52^SER 46^SER 119^GLY 117^ASN	0.0.0.0	defense response	plasma membrane cell outer membrane membrane
2v3rA exoglucanase 1	[pdb]	1.37 0.00265	392^ALA 378^ASP 379^SER 398^SER 269^GLY 264^ASN	3.2.1.91	polysaccharide catabolic process carbohydrate metabolic process metabolic process cellulose catabolic process	extracellular region	hydrolase activity hydrolyzing O-glycosyl compounds cellulose 1,4-beta-cellobiosidase activity hydrolase activity hydrolase activity
2vdcB glutamate synthase [nadph] large chain glutamate synthase [nadph] small chain	[pdb]	1.37 0.00265	24^ALA 368^HIS 367^ILE 351^GLU 30^GLU 1237^ASN	1.4.1.13	glutamate biosynthetic process glutamine metabolic process nitrogen compound metabolic process metabolic process cellular amino acid biosynthetic process oxidation-reduction process glutamate biosynthetic process metabolic process cellular amino acid biosynthetic process oxidation-reduction process		catalytic activity glutamate synthase (NADPH) activity glutamate synthase activity oxidoreductase activity metal ion binding iron-sulfur cluster binding 3 iron 4 sulfur cluster binding catalytic activity glutamate synthase (NADPH) activity binding oxidoreductase activity oxidoreductase activity acting on the CH-NH2 group of donors NAD or NADP as acceptor metal ion binding
1s3rB intermedilysin	[pdb]	1.37 0.00265	426^ASP 523^GLU 512^SER 509^ARG 485^GLY 521^GLN	0.0.0.0	pathogenesis		cholesterol binding
1eepA inosine 5'-monophosphate dehydrogenase	[pdb]	1.37 0.00266	51^ASP 293^GLU 294^SER 349^SER 69^GLY 57^GLN	1.1.1.205	purine nucleotide biosynthetic process GMP biosynthetic process metabolic process oxidation-reduction process		catalytic activity IMP dehydrogenase activity oxidoreductase activity metal ion binding
2wiuC protein hipa hth-type transcriptional regulator hipb	[pdb]	1.38 0.00278	312^ALA 253^GLU 316^SER 326^ARG 260^GLY 63^SER	0.0.0.0	dormancy process		DNA binding transcription repressor activity sequence-specific DNA binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding
3kehB glucocerebrosidase	[pdb]	1.38 0.00278	164^ALA 111^GLU 110^SER 25^SER 82^GLY 117^ASN	3.2.1.45	carbohydrate metabolic process lipid metabolic process sphingolipid metabolic process lysosome organization metabolic process cell death	lysosome lysosomal membrane membrane	catalytic activity glucosylceramidase activity protein binding hydrolase activity hydrolase activity acting on glycosyl bonds
3bu0A dna (5'-d(dtpdcpdgpdcpdapdapdtpdapdapdtpdapdcpda)-3') dna (5'-d(dcpdtpdgpdtpdapdtpdcpdapdtpdtpdgpdcpdg)-3') alpha-ketoglutarate-dependent dioxygenase alkbhomolog 2	[pdb]	1.38 0.00278	212^ALA 201^ASP 202^SER 206^SER 236^HIS 233^HIS	0.0.0.0	DNA repair DNA dealkylation involved in DNA repair response to DNA damage stimulus oxidative DNA demethylation oxidation-reduction process oxidative demethylation DNA demethylation	nucleus nucleoplasm	damaged DNA binding ferrous iron binding 2-oxoglutarate-dependent dioxygenase activity oxidoreductase activity oxidoreductase activity acting on single donors with incorporation of molecular oxygen incorporation of two atoms of oxygen DNA-N1-methyladenine dioxygenase activity
1ryeB glucose-fructose oxidoreductase	[pdb]	1.38 0.00291	52^ALA 330^ASP 326^SER 157^ARG 33^GLY 56^HIS	1.1.99.28	metabolic process oxidation-reduction process	periplasmic space	catalytic activity binding oxidoreductase activity glucose-fructose oxidoreductase activity
2ri9A mannosyl-oligosaccharide alpha-1,2-mannosidase	[pdb]	1.38 0.00291	1051^ALA 1466^GLU 1467^SER 1126^ARG 1072^HIS 1464^ASN	3.2.1.113	metabolic process	extracellular region membrane	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity calcium ion binding hydrolase activity hydrolase activity
1jbiA cochlin	[pdb]	1.38 0.00291	50^ALA 79^ASP 85^SER 76^SER 55^GLY 81^ASN	0.0.0.0	sensory perception of sound	extracellular region proteinaceous extracellular matrix
3o8oE 6-phosphofructokinase subunit beta 6-phosphofructokinase subunit alpha	[pdb]	1.39 0.00291	216^ARG 356^ALA 354^THR 364^LEU 493^ARG 490^ALA		glycolysis proton transport glycolysis proton transport	cytoplasm mitochondrion 6-phosphofructokinase complex cytoplasm mitochondrion 6-phosphofructokinase complex	nucleotide binding 6-phosphofructokinase activity protein binding ATP binding kinase activity transferase activity metal ion binding proton-transporting ATPase activity rotational mechanism nucleotide binding 6-phosphofructokinase activity protein binding ATP binding kinase activity transferase activity
1tuoA putative phosphomannomutase	[pdb]	1.39 0.00291	249^ASP 211^GLU 184^SER 207^ARG 219^GLY 214^HIS	0.0.0.0	carbohydrate metabolic process		intramolecular transferase activity
3mlxM human monoclonal anti-hiv-1 gp120 v3 antibody 3074 fabheavy chain hiv-1 gp120 third variable region (v3) crown human monoclonal anti-hiv-1 gp120 v3 antibody 3074 fablight chain	[pdb]	1.39 0.00291	89^VAL 50^TYR 34^TRP 63^LEU 29^ILE 31^GLY	0.0.0.0	apoptosis initiation of viral infection evasion by virus of host immune response interspecies interaction between organisms	membrane integral to membrane virion viral envelope host cell plasma membrane host cell membrane host cell endosome host cell endosome membrane virion membrane	structural molecule activity
1qlrB igm kappa chain v-iii (kau cold agglutinin) igm fab region iv-j(h4)-c (kau cold agglutinin)	[pdb]	1.39 0.00305	96^ALA 50^GLU 35^SER 70^SER 100^HIS 105^HIS	0.0.0.0
2f00B udp-n-acetylmuramate--l-alanine ligase	[pdb]	1.39 0.00305	198^ASP 176^ASP 178^SER 86^SER 353^GLY 128^HIS	6.3.2.8	cellular cell wall organization cell cycle metabolic process regulation of cell shape biosynthetic process peptidoglycan biosynthetic process peptidoglycan-based cell wall biogenesis cell division	cytoplasm	nucleotide binding magnesium ion binding catalytic activity binding protein binding ATP binding UDP-N-acetylmuramate-L-alanine ligase activity ligase activity
1yqdB sinapyl alcohol dehydrogenase	[pdb]	1.39 0.00305	60^ASP 53^ASP 56^SER 126^SER 278^GLY 51^HIS	0.0.0.0	metabolic process oxidation-reduction process		catalytic activity binding zinc ion binding oxidoreductase activity metal ion binding
3e1yC eukaryotic peptide chain release factor gtp-binding subunit erf3a eukaryotic peptide chain release factor subunit1	[pdb]	1.39 0.00305	227^ALA 269^GLU 271^SER 276^SER 159^GLY 265^ASN		translation translational termination regulation of translational termination protein methylation G1/S transition of mitotic cell cycle nuclear-transcribed mRNA catabolic process nonsense-mediated decay translation protein methylation activation of caspase activity protein ubiquitination	cytoplasm intracellular	RNA binding translation release factor activity protein binding translation termination factor activity translation release factor activity codon specific ribosome binding nucleotide binding translation release factor activity GTPase activity protein binding
2a9mL fluorescein-scfv heavy chain fluorescein-scfv light chain	[pdb]	1.39 0.00305	107^ALA 58^LEU 42^SER 79^THR 32^GLY 39^PHE
2a1lA phosphatidylinositol transfer protein betaisoform	[pdb]	1.4 0.00305	192^ALA 17^GLU 14^SER 187^CYS 225^HIS 22^GLN	0.0.0.0	transport	intracellular cytoplasm Golgi apparatus	lipid binding phosphatidylinositol transporter activity
1p7zD catalase hpii	[pdb]	1.4 0.00319	57^ALA 380^ASP 54^SER 72^ARG 136^GLY 378^ASN	1.11.1.6	response to oxidative stress hydrogen peroxide catabolic process oxidation-reduction process	cytoplasm cytosol	catalase activity peroxidase activity iron ion binding protein binding oxidoreductase activity heme binding metal ion binding
2dnnA rna-binding protein 12	[pdb]	1.4 0.00319	307^ALA 303^GLU 305^SER 292^ARG 263^HIS 275^ASN	0.0.0.0		nucleus	nucleotide binding nucleic acid binding RNA binding protein binding
1xs2D n-acylamino acid racemase	[pdb]	1.4 0.00319	227^ASP 246^GLU 247^SER 250^SER 263^GLY 221^GLN	0.0.0.0	metabolic process		catalytic activity metal ion binding
1eakC inhibitor peptide 72 kda type iv collagenase	[pdb]	1.4 0.00319	192^ALA 204^ASP 205^SER 127^ARG 403^HIS 407^HIS	3.4.24.24	angiogenesis response to hypoxia blood vessel maturation intramembranous ossification proteolysis metabolic process collagen catabolic process skeletal system morphogenesis face morphogenesis bone trabecula formation	extracellular region proteinaceous extracellular matrix extracellular space nucleus plasma membrane membrane sarcomere extracellular matrix intracellular membrane-bounded organelle	metalloendopeptidase activity protein binding peptidase activity metallopeptidase activity zinc ion binding hydrolase activity metal ion binding
2r5rA upf0343 protein ne1163	[pdb]	1.4 0.00334	24^ASP 97^GLU 98^SER 90^ARG 63^GLY 60^ASN	3.5.4.16	purine base metabolic process oxidation-reduction process		GTP cyclohydrolase I activity oxidoreductase activity hydrolase activity
2odpA complement c2	[pdb]	1.42 0.00349	450^ALA 456^GLU 453^SER 507^SER 431^HIS 447^ASN	3.4.21.43	proteolysis complement activation complement activation alternative pathway complement activation	extracellular region extracellular space	catalytic activity serine-type endopeptidase activity peptidase activity serine-type peptidase activity hydrolase activity
1cfeA pathogenesis-related protein p14a	[pdb]	1.42 0.00365	67^ALA 53^GLU 120^SER 32^ARG 11^HIS 96^GLN	0.0.0.0	defense response response to biotic stimulus killing of cells of other organism defense response to fungus	extracellular region
3l2pA 5'-d(gptpcpgpgpapcptpg)-3' 5'-d(gpcpcpapgptpcpcpgpapcpgpapcpgpcpaptpcpcpcpg)-3' 5'-d(pcpgpgpgpaptpgpcpgptpc)-3' dna ligase 3	[pdb]	1.42 0.00365	236^ASP 265^GLU 264^SER 324^CYS 615^GLY 260^GLN	6.5.1.1	DNA replication DNA repair DNA recombination response to DNA damage stimulus cell cycle reciprocal meiotic recombination spermatogenesis cell division V(D)J recombination	intracellular nucleus nucleoplasm	nucleotide binding DNA binding DNA ligase activity DNA ligase (ATP) activity protein binding ATP binding zinc ion binding ligase activity metal ion binding
2vtzB acetyl-coa acetyltransferase	[pdb]	1.42 0.00365	122^ALA 117^GLU 118^SER 17^SER 147^GLY 56^GLN	2.3.1.9	metabolic process poly-hydroxybutyrate biosynthetic process	cytoplasm	catalytic activity acetyl-CoA C-acetyltransferase activity acyltransferase activity transferase activity transferase activity
2cduA nadph oxidase	[pdb]	1.42 0.00365	279^ALA 282^ASP 283^SER 246^ARG 287^HIS 302^ASN	0.0.0.0	cell redox homeostasis oxidation-reduction process	cytoplasm	oxidoreductase activity flavin adenine dinucleotide binding
3ez1A aminotransferase mocr family	[pdb]	1.43 0.00381	248^ALA 98^GLU 96^SER 135^ARG 259^GLY 93^ASN	0.0.0.0			catalytic activity transaminase activity transferase activity pyridoxal phosphate binding
2eceA 462aa long hypothetical selenium-binding protein	[pdb]	1.43 0.00381	327^ASP 331^ASP 329^SER 426^SER 267^GLY 260^HIS	0.0.0.0			selenium binding
1cn1B concanavalin a	[pdb]	1.43 0.00397	44^ASP 203^ASP 201^SER 164^SER 209^GLY 205^HIS	0.0.0.0			binding protein binding sugar binding mannose binding metal ion binding
3fm3B methionine aminopeptidase 2	[pdb]	1.43 0.00397	52^ALA 136^ASP 135^SER 91^ARG 21^GLY 46^GLN	3.4.11.18	proteolysis cellular process		aminopeptidase activity peptidase activity metalloexopeptidase activity hydrolase activity metal ion binding
2j9aA microginin fr1 cytosol aminopeptidase	[pdb]	1.43 0.00397	395^ASP 388^GLU 390^SER 481^ARG 83^HIS 81^ASN	3.4.11.1, 3.4.11.5	proteolysis protein metabolic process	intracellular cytoplasm mitochondrion	aminopeptidase activity peptidase activity metalloexopeptidase activity hydrolase activity manganese ion binding metal ion binding
2y5eA limit dextrinase	[pdb]	1.44 0.00397	760^ASP 855^ASP 757^SER 665^ARG 847^HIS 852^ASN	0.0.0.0	carbohydrate metabolic process		catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds cation binding
1f1rB homoprotocatechuate 2,3-dioxygenase	[pdb]	1.44 0.00397	272^ASP 179^GLU 251^SER 292^ARG 155^HIS 194^HIS	0.0.0.0			oxidoreductase activity
1ybjA hemophore hasa	[pdb]	1.44 0.00414	68^ALA 89^ASP 90^SER 3^SER 132^HIS 87^GLN	0.0.0.0		extracellular region	metal ion binding
3ck2A conserved uncharacterized protein (predictedphosphoesterase cog0622)	[pdb]	1.44 0.00414	11^ASP 40^GLU 39^SER 45^SER 81^HIS 57^ASN	0.0.0.0
3cmnA putative hydrolase	[pdb]	1.44 0.00414	288^ALA 380^GLU 377^SER 390^ARG 295^GLY 348^GLN	0.0.0.0
1uyrA acetyl-coa carboxylase	[pdb]	1.44 0.00414	2098^ASP 2112^GLU 2100^SER 2110^SER 1993^GLY 2019^ASN	6.3.4.14, 6.4.1.2	protein import into nucleus fatty acid biosynthetic process nuclear envelope organization metabolic process lipid biosynthetic process	cytoplasm mitochondrion endoplasmic reticulum membrane	nucleotide binding catalytic activity acetyl-CoA carboxylase activity biotin carboxylase activity ATP binding biotin binding ligase activity metal ion binding
2xdvA myc-induced nuclear antigen	[pdb]	1.44 0.00414	246^ALA 243^ASP 173^SER 132^ARG 192^GLY 195^HIS	0.0.0.0	ribosome biogenesis	nucleus nucleolus cytoplasm
3h6eA carbohydrate kinase, fggy	[pdb]	1.44 0.00414	235^ALA 422^ASP 424^SER 16^SER 393^GLY 420^HIS	0.0.0.0	carbohydrate metabolic process		kinase activity phosphotransferase activity
3b4uB dihydrodipicolinate synthase	[pdb]	1.44 0.00414	9^ALA 39^ASP 40^SER 73^SER 29^HIS 36^ASN	0.0.0.0	metabolic process		catalytic activity lyase activity
1p3dB udp-n-acetylmuramate--alanine ligase	[pdb]	1.44 0.00414	197^ASP 175^ASP 177^SER 85^SER 348^HIS 127^HIS	6.3.2.8	cellular cell wall organization cell cycle metabolic process regulation of cell shape biosynthetic process peptidoglycan biosynthetic process peptidoglycan-based cell wall biogenesis cell division	cytoplasm	nucleotide binding catalytic activity binding ATP binding UDP-N-acetylmuramate-L-alanine ligase activity ligase activity
2okxA rhamnosidase b	[pdb]	1.44 0.00414	483^ASP 572^GLU 570^SER 448^SER 149^GLY 147^GLN	0.0.0.0			catalytic activity
2db3D atp-dependent rna helicase vasa 5'-r(upupupupupupupupupu)-3'	[pdb]	1.45 0.00414	287^ALA 402^ASP 432^SER 325^SER 444^GLY 440^GLN	0.0.0.0	mRNA polyadenylation regulation of translation multicellular organismal development germarium-derived egg chamber formation germarium-derived oocyte fate determination oocyte anterior/posterior axis specification pole plasm assembly pole plasm RNA localization intracellular mRNA localization cell differentiation karyosome formation positive regulation of translation regulation of oskar mRNA translation positive regulation of oskar mRNA translation dorsal appendage formation germ-line cyst formation oogenesis	cytoplasm P granule	nucleotide binding nucleic acid binding RNA binding RNA helicase activity mRNA 3'-UTR binding ATP-dependent RNA helicase activity helicase activity protein binding ATP binding ATP-dependent helicase activity hydrolase activity
3lduA putative methylase	[pdb]	1.45 0.00432	156^ASP 228^GLU 227^SER 231^ARG 45^GLY 50^ASN	0.0.0.0	methylation		nucleic acid binding methyltransferase activity
2owoA dna ligase 26-mer 5'-d(cpapcptpaptpcpgpgpapaptpg)-3' 5'-d(apcpapaptptpgpcpgpapcp(omc)pc)-3'	[pdb]	1.45 0.00432	134^ALA 169^GLU 122^SER 224^CYS 139^GLY 75^HIS	6.5.1.2	DNA replication DNA repair response to DNA damage stimulus	intracellular	DNA binding DNA ligase (NAD+) activity ligase activity metal ion binding
1f89B 32.5 kda protein ylr351c	[pdb]	1.45 0.00432	471^ASP 353^GLU 493^SER 538^SER 426^HIS 411^ASN	0.0.0.0	nitrogen compound metabolic process	cytoplasm mitochondrion	hydrolase activity hydrolase activity
2vdxA corticosteroid-binding globulin	[pdb]	1.45 0.00432	51^ALA 130^GLU 131^SER 122^SER 86^GLY 91^HIS	0.0.0.0	transport glucocorticoid metabolic process	extracellular region extracellular space	serine-type endopeptidase inhibitor activity steroid binding lipid binding
1hovA matrix metalloproteinase-2	[pdb]	1.45 0.00451	84^ALA 96^ASP 97^SER 19^ARG 120^HIS 124^HIS	3.4.24.24	angiogenesis response to hypoxia blood vessel maturation intramembranous ossification proteolysis metabolic process collagen catabolic process skeletal system morphogenesis face morphogenesis bone trabecula formation	extracellular region proteinaceous extracellular matrix extracellular space nucleus plasma membrane membrane sarcomere extracellular matrix intracellular membrane-bounded organelle	metalloendopeptidase activity protein binding peptidase activity metallopeptidase activity zinc ion binding hydrolase activity metal ion binding
3ce9C glycerol dehydrogenase	[pdb]	1.46 0.00451	273^ALA 171^ASP 174^SER 201^SER 254^HIS 266^HIS	0.0.0.0	aromatic amino acid family biosynthetic process oxidation-reduction process		3-dehydroquinate synthase activity oxidoreductase activity acting on CH-OH group of donors
2kxfA poly(u)-binding-splicing factor puf60	[pdb]	1.46 0.00451	219^ASP 222^ASP 221^SER 227^SER 251^GLY 249^HIS	0.0.0.0	mRNA processing apoptosis RNA splicing	nucleus ribonucleoprotein complex cyclin-dependent protein kinase activating kinase holoenzyme complex	nucleotide binding nucleic acid binding DNA binding RNA binding protein binding
3ctzA xaa-pro aminopeptidase 1	[pdb]	1.46 0.00451	201^ALA 41^GLU 40^SER 34^SER 500^GLY 496^ASN	3.4.11.9	proteolysis cellular process bradykinin catabolic process	cytoplasm	aminopeptidase activity peptidase activity metalloexopeptidase activity metallopeptidase activity hydrolase activity manganese ion binding protein homodimerization activity metal ion binding metalloaminopeptidase activity
3nuhB dna gyrase subunit b dna gyrase subunit a	[pdb]	1.46 0.00451	414^ASP 419^GLU 418^SER 438^ARG 475^GLY 491^HIS	5.99.1.3	DNA metabolic process DNA-dependent DNA replication DNA topological change regulation of transcription DNA-dependent response to drug response to antibiotic DNA-dependent DNA replication DNA topological change response to drug	chromosome cytoplasm DNA topoisomerase complex (ATP-hydrolyzing) membrane chromosome cytoplasm DNA topoisomerase complex (ATP-hydrolyzing)	nucleotide binding DNA binding sequence-specific DNA binding transcription factor activity DNA topoisomerase activity DNA topoisomerase (ATP-hydrolyzing) activity ATP binding DNA-dependent ATPase activity isomerase activity nucleotide binding DNA binding DNA topoisomerase activity DNA topoisomerase (ATP-hydrolyzing) activity ATP binding DNA-dependent ATPase activity isomerase activity
1fqvG skp2 skp1	[pdb]	1.46 0.0047	409^ALA 199^ASP 224^SER 179^ARG 423^GLY 197^HIS	0.0.0.0	G1/S transition of mitotic cell cycle cell proliferation ubiquitin-dependent protein catabolic process protein ubiquitination SCF-dependent proteasomal ubiquitin-dependent protein catabolic process positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	SCF ubiquitin ligase complex nucleoplasm cytosol SCF ubiquitin ligase complex	protein binding ubiquitin-protein ligase activity protein binding
3fvrI acetyl xylan esterase	[pdb]	1.46 0.0047	279^ALA 249^ASP 208^SER 181^SER 255^GLY 252^ASN	0.0.0.0			acetylesterase activity hydrolase activity
3ombA extracellular solute-binding protein, family 1	[pdb]	1.46 0.0047	463^ASP 244^GLU 243^SER 256^SER 343^GLY 239^ASN	0.0.0.0	transport		transporter activity
2pmbB uncharacterized protein	[pdb]	1.46 0.0047	141^ALA 100^GLU 104^SER 43^SER 215^GLY 232^ASN	0.0.0.0
2hrpL hiv-1 protease peptide monoclonal antibody f11.2.32	[pdb]	1.46 0.0047	12^VAL 82^LEU 83^ARG 168^ALA 16^GLY 76^ASN	0.0.0.0			antigen binding protein binding
1r64B kexin ac-arg-glu-lys-boroarg peptide inhibitor	[pdb]	1.46 0.0047	325^ASP 350^GLU 312^SER 385^SER 279^GLY 321^ASN	3.4.21.61	proteolysis peptide pheromone maturation	Golgi apparatus trans-Golgi network membrane integral to membrane	serine-type endopeptidase activity protein binding peptidase activity serine-type peptidase activity hydrolase activity metal ion binding
2c0oA tyrosine-protein kinase hck	[pdb]	1.47 0.0047	363^ALA 418^ASP 421^SER 472^CYS 347^GLY 358^HIS	2.7.10.2	protein phosphorylation phagocytosis mesoderm development interspecies interaction between organisms defense response to Gram-positive bacterium	cytoplasm caveola membrane	nucleotide binding protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein binding ATP binding kinase activity transferase activity
2qtkB probable porin	[pdb]	1.47 0.0047	88^ALA 78^GLU 77^SER 22^ARG 65^GLY 159^ASN	0.0.0.0	transport	integral to membrane	porin activity
3mi6D alpha-galactosidase	[pdb]	1.47 0.0049	545^ALA 550^ASP 548^SER 202^ARG 600^GLY 575^HIS	0.0.0.0	carbohydrate metabolic process metabolic process		catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds
1yq4A succinate dehydrogenase ip subunit succinate dehydrogenase cytochrome b, smallsubunit succinate dehydrogenase cytochrome b, largesubunit succinate dehydrogenase flavoprotein subunit	[pdb]	1.47 0.0049	88^TYR 544^GLU 545^SER 484^ARG 582^HIS 578^HIS	1.3.5.1	tricarboxylic acid cycle succinate metabolic process transport nervous system development electron transport chain respiratory electron transport chain oxidation-reduction process tricarboxylic acid cycle transport electron transport chain tricarboxylic acid cycle transport electron transport chain oxidation-reduction process	mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex II membrane mitochondrion mitochondrial envelope mitochondrial inner membrane mitochondrial respiratory chain complex II membrane integral to membrane mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex II membrane	succinate dehydrogenase activity protein binding succinate dehydrogenase (ubiquinone) activity electron carrier activity oxidoreductase activity oxidoreductase activity acting on the CH-CH group of donors flavin adenine dinucleotide binding succinate dehydrogenase activity iron ion binding heme binding metal ion binding ubiquinone binding protein binding succinate dehydrogenase (ubiquinone) activity electron carrier activity oxidoreductase activity metal ion binding ubiquinone binding iron-sulfur cluster binding 2 iron 2 sulfur cluster binding
2y0sA rna polymerase subunit 4 rna polymerase subunit 7 rna polymerase subunit 8 dna-directed rna polymerase subunit d dna-directed rna polymerase subunit a'' dna-directed rna polymerase subunit h dna-directed rna polymerase subunit k dna-directed rna polymerase subunit l dna-directed rna polymerase subunit n dna-directed rna polymerase rna polymerase subunit 12 rna polymerase subunit 13	[pdb]	1.47 0.0049	629^ASP 335^THR 333^GLY 444^ARG 497^GLY 483^HIS		cellular metabolic process transcription DNA-dependent transcription	RNA polymerase complex	DNA binding DNA-directed RNA polymerase activity zinc ion binding transferase activity nucleotidyltransferase activity DNA binding DNA-directed RNA polymerase activity DNA binding DNA-directed RNA polymerase activity zinc ion binding transferase activity nucleotidyltransferase activity ribonucleoside binding DNA binding DNA-directed RNA polymerase activity protein dimerization activity DNA binding RNA binding DNA-directed RNA polymerase activity nucleotide binding catalytic activity DNA-directed RNA polymerase activity DNA binding DNA-directed RNA polymerase activity transferase activity nucleotidyltransferase activity DNA binding DNA-directed RNA polymerase activity transferase activity nucleotidyltransferase activity DNA binding DNA-directed RNA polymerase activity protein dimerization activity DNA binding DNA-directed RNA polymerase activity zinc ion binding transferase activity nucleotidyltransferase activity metal ion binding DNA binding DNA-directed RNA polymerase activity
3kw8A putative copper oxidase	[pdb]	1.47 0.0049	113^ASP 121^ASP 120^SER 128^ARG 156^HIS 158^HIS	0.0.0.0	oxidation-reduction process		copper ion binding oxidoreductase activity
2jbwA 2,6-dihydroxy-pseudo-oxynicotine hydrolase	[pdb]	1.47 0.00511	283^ASP 244^ASP 243^SER 238^SER 187^GLY 276^HIS	0.0.0.0	alkaloid metabolic process		hydrolase activity
3qz4A endo-1,4-beta-xylanase d	[pdb]	1.48 0.00511	39^ASP 58^ASP 57^SER 66^SER 308^GLY 310^HIS
1gvhA flavohemoprotein	[pdb]	1.48 0.00511	344^ASP 338^ASP 339^SER 332^ARG 294^HIS 321^HIS	1.14.12.17	transport response to toxin oxygen transport oxidation-reduction process	cytoplasm	oxygen transporter activity iron ion binding nitric oxide dioxygenase activity oxidoreductase activity oxygen binding heme binding metal ion binding
2dqbF deoxyguanosinetriphosphate triphosphohydrolase,putative	[pdb]	1.48 0.00511	196^ASP 102^GLU 87^SER 92^ARG 169^HIS 108^HIS		GTP metabolic process		magnesium ion binding catalytic activity dGTPase activity hydrolase activity
1sqjA oligoxyloglucan reducing-end-specificcellobiohydrolase	[pdb]	1.48 0.00511	493^ASP 598^ASP 597^SER 616^SER 555^GLY 497^ASN	0.0.0.0	polysaccharide catabolic process carbohydrate metabolic process metabolic process cellulose catabolic process		hydrolase activity hydrolase activity acting on glycosyl bonds
2j4oA mitogen-activated protein kinase kinase kinase7-interacting protein 1	[pdb]	1.48 0.00533	81^ALA 51^ASP 52^SER 289^SER 165^GLY 74^ASN	0.0.0.0	activation of MAPKKK activity in utero embryonic development heart morphogenesis transforming growth factor beta receptor signaling pathway lung development	endosome membrane	catalytic activity protein binding enzyme activator activity kinase activator activity
1uaaA protein (atp-dependent dna helicase rep.) dna (5'-d(tptptptptptptptptptptptptptptpt)-3')	[pdb]	1.49 0.00556	596^ALA 575^GLU 627^SER 316^SER 351^GLY 580^HIS	0.0.0.0	DNA replication DNA unwinding involved in replication DNA repair	cytoplasm	nucleotide binding DNA binding ATP-dependent DNA helicase activity helicase activity ATP binding hydrolase activity
1lbsF lipase b	[pdb]	1.49 0.00556	274^ALA 49^ASP 50^SER 56^SER 39^GLY 46^GLN		lipid catabolic process		triglyceride lipase activity hydrolase activity
3icfA serine/threonine-protein phosphatase t	[pdb]	1.49 0.00556	256^ASP 249^ASP 454^SER 437^ARG 283^GLY 251^HIS	3.1.3.16	protein dephosphorylation	nucleus cytoplasm	phosphoprotein phosphatase activity protein serine/threonine phosphatase activity binding hydrolase activity metal ion binding
1gc5A adp-dependent glucokinase	[pdb]	1.49 0.00556	359^ALA 347^GLU 301^SER 276^SER 365^GLY 362^GLN	2.7.1.147	carbohydrate metabolic process glucose metabolic process glycolysis	cytoplasm	magnesium ion binding kinase activity transferase activity phosphotransferase activity alcohol group as acceptor ADP-specific glucokinase activity
1hr6A mitochondrial processing peptidase alpha subunit mitochondrial processing peptidase beta subunit	[pdb]	1.49 0.00556	269^ALA 325^SER 324^MET 97^SER 265^THR 434^LEU	3.4.24.64	proteolysis protein processing involved in protein targeting to mitochondrion proteolysis protein processing involved in protein targeting to mitochondrion	mitochondrion mitochondrial matrix mitochondrial processing peptidase complex mitochondrion mitochondrial matrix mitochondrial processing peptidase complex	catalytic activity metalloendopeptidase activity protein binding peptidase activity metallopeptidase activity zinc ion binding hydrolase activity metal ion binding catalytic activity metalloendopeptidase activity protein binding peptidase activity metallopeptidase activity zinc ion binding hydrolase activity metal ion binding
2pt7D cag-alfa hypothetical protein	[pdb]	1.5 0.0058	294^ALA 253^GLU 252^ASP 250^LEU 305^GLY 259^ASN	0.0.0.0	transport pathogenesis	intracellular cytoplasm	protein binding protein binding ATP binding
1nphA gelsolin	[pdb]	1.5 0.0058	560^ALA 565^ASP 563^SER 629^ARG 735^GLY 540^GLN	0.0.0.0	apoptosis aging actin polymerization or depolymerization oligodendrocyte development vesicle-mediated transport actin filament polymerization regulation of cell adhesion wound healing tissue regeneration response to ethanol response to cadmium ion phosphatidylinositol-mediated signaling actin filament severing response to folic acid actin filament capping	extracellular region extracellular space cytoplasm cytosol cytoskeleton lamellipodium protein complex perinuclear region of cytoplasm	actin binding protein binding
2fonB peroxisomal acyl-coa oxidase 1a	[pdb]	1.5 0.0058	522^ALA 488^GLU 491^SER 460^ARG 379^GLY 528^GLN	0.0.0.0	fatty acid metabolic process fatty acid beta-oxidation metabolic process oxidation-reduction process	peroxisome	acyl-CoA dehydrogenase activity acyl-CoA oxidase activity oxidoreductase activity oxidoreductase activity acting on the CH-CH group of donors
2c3mB pyruvate-ferredoxin oxidoreductase	[pdb]	1.5 0.0058	9^ASP 148^GLU 145^SER 280^CYS 110^HIS 150^HIS	0.0.0.0	metabolic process oxidation-reduction process		catalytic activity iron ion binding electron carrier activity oxidoreductase activity oxidoreductase activity acting on the aldehyde or oxo group of donors thiamine pyrophosphate binding
1i5pA pesticidial crystal protein cry2aa	[pdb]	1.5 0.00606	411^ALA 396^GLU 397^SER 466^SER 381^GLY 394^GLN	0.0.0.0	defense response pathogenesis sporulation resulting in formation of a cellular spore		receptor binding