The LabelHash Server

Top 150 matches

For each match you can click on the "[pdb]" link to download a PDB file with the matching chain aligned with the motif.
Download a zip file with PDB files for all the matches and the motif itself.

PDB ID		LRMSD / p-value	Matching Residues	EC	Gene Ontology annotations
PDB ID		LRMSD / p-value	Matching Residues	EC	Biological Process	Cellular Component	Molecular Function
1pysA phenylalanyl-trna synthetase	[pdb]	0.4 1.77e-05	149^ALA 178^HIS 180^LEU 206^ASP 218^ALA 258^GLN 260^MET	6.1.1.20	translation phenylalanyl-tRNA aminoacylation tRNA processing translation tRNA aminoacylation for protein translation phenylalanyl-tRNA aminoacylation	cytoplasm cytoplasm	tRNA binding nucleotide binding magnesium ion binding RNA binding aminoacyl-tRNA ligase activity phenylalanine-tRNA ligase activity ATP binding ligase activity metal ion binding tRNA binding nucleotide binding aminoacyl-tRNA ligase activity phenylalanine-tRNA ligase activity ATP binding ligase activity metal ion binding
3l4gK phenylalanyl-trna synthetase beta chain phenylalanyl-trna synthetase alpha chain	[pdb]	0.981 5.75e-05	270^ILE 327^LEU 329^LYS 360^HIS 372^TYR 410^THR 412^ALA	6.1.1.20	translation phenylalanyl-tRNA aminoacylation translation tRNA aminoacylation for protein translation phenylalanyl-tRNA aminoacylation	soluble fraction cytoplasm cytosol soluble fraction cytoplasm cytosol	nucleotide binding magnesium ion binding RNA binding aminoacyl-tRNA ligase activity phenylalanine-tRNA ligase activity ATP binding ligase activity tRNA binding nucleotide binding aminoacyl-tRNA ligase activity phenylalanine-tRNA ligase activity ATP binding ligase activity
1lm5B subdomain of desmoplakin carboxy-terminal domain(dpct)	[pdb]	1.34 0.000118	2735^GLY 2765^GLN 2767^THR 2749^GLU 2762^GLN 2729^PHE 2785^TYR	0.0.0.0	epidermis development cell-cell adhesion peptide cross-linking keratinocyte differentiation adherens junction organization wound healing skin development	cornified envelope cytoplasm mitochondrion cytoskeleton plasma membrane fascia adherens basolateral plasma membrane cell junction desmosome	structural molecule activity structural constituent of cytoskeleton protein binding protein binding
1ua8A outer-membrane lipoproteins carrier protein	[pdb]	1.38 0.00015	94^ALA 17^HIS 19^SER 43^ARG 158^GLN 140^PHE 152^TYR	0.0.0.0	transport protein transport lipoprotein transport	outer membrane-bounded periplasmic space periplasmic space	protein binding
3juyC 3b3 single chain variant hiv-1 antibody	[pdb]	1.4 0.000164	117^TRP 3^GLN 25^SER 188^ARG 1^GLN 32^PHE 29^PHE
3h09B immunoglobulin a1 protease	[pdb]	1.45 0.000238	256^GLY 159^GLN 145^THR 253^GLU 157^GLN 165^TYR 143^TYR	3.4.21.72	proteolysis pathogenesis	extracellular region plasma membrane cell outer membrane cell surface membrane integral to membrane outer membrane periplasmic space	serine-type endopeptidase activity peptidase activity serine-type peptidase activity hydrolase activity
3lopA substrate binding periplasmic protein	[pdb]	1.48 0.000307	236^ALA 48^GLN 212^THR 315^ARG 86^GLN 178^TYR 208^TYR	0.0.0.0
3lsuA superoxide dismutase [mn], mitochondrial	[pdb]	1.51 0.000381	66^ALA 44^GLN 40^THR 62^ARG 46^GLN 73^PHE 34^TYR		replicative cell aging age-dependent response to reactive oxygen species involved in chronological cell aging age-dependent response to oxidative stress involved in chronological cell aging oxygen and reactive oxygen species metabolic process superoxide metabolic process oxidation-reduction process	mitochondrion mitochondrial matrix	superoxide dismutase activity protein binding oxidoreductase activity metal ion binding
1w6jA lanosterol synthase	[pdb]	1.52 0.000402	693^ALA 648^GLN 652^THR 146^GLU 646^GLN 709^ASN 711^PHE	5.4.99.7	steroid biosynthetic process cholesterol biosynthetic process steroid metabolic process lipid biosynthetic process sterol metabolic process	endoplasmic reticulum endoplasmic reticulum membrane microsome membrane	lanosterol synthase activity catalytic activity isomerase activity intramolecular transferase activity
1e6yA methyl-coenzyme m reductase i gamma subunit methyl-coenzyme m reductase i beta subunit methyl-coenzyme m reductase i alpha subunit	[pdb]	1.53 0.000447	1507^GLY 1420^GLN 1419^SER 1319^GLU 1345^GLN 1501^ASN 1466^PHE	2.8.4.1	methanogenesis methanogenesis methanogenesis		transferase activity metal ion binding coenzyme-B sulfoethylthiotransferase activity transferase activity coenzyme-B sulfoethylthiotransferase activity transferase activity coenzyme-B sulfoethylthiotransferase activity
1xfdD dipeptidyl aminopeptidase-like protein 6	[pdb]	1.54 0.000472	245^ALA 301^HIS 289^SER 191^ARG 212^GLN 260^ASN 285^TYR	0.0.0.0	proteolysis cell death	membrane integral to membrane	dipeptidyl-peptidase activity
1xkwA fe(iii)-pyochelin receptor	[pdb]	1.54 0.000472	244^GLY 263^GLN 302^THR 206^ASP 148^GLN 306^PHE 325^TYR	0.0.0.0	transport ion transport iron ion transport siderophore transport	plasma membrane cell outer membrane membrane integral to membrane	receptor activity transporter activity iron ion binding siderophore transmembrane transporter activity
2rhsA phenylalanyl-trna synthetase beta chain phenylalanyl-trna synthetase alpha chain	[pdb]	1.54 0.000499	154^LEU 172^ARG 174^ASP 202^GLU 214^THR 254^ASN 256^VAL	6.1.1.20	translation tRNA aminoacylation for protein translation phenylalanyl-tRNA aminoacylation translation phenylalanyl-tRNA aminoacylation tRNA processing	cytoplasm cytoplasm	tRNA binding nucleotide binding aminoacyl-tRNA ligase activity phenylalanine-tRNA ligase activity ATP binding ligase activity metal ion binding tRNA binding nucleotide binding magnesium ion binding RNA binding aminoacyl-tRNA ligase activity phenylalanine-tRNA ligase activity ATP binding ligase activity metal ion binding
3gjzB microcin immunity protein mccf	[pdb]	1.55 0.000499	297^ALA 268^HIS 304^THR 282^GLU 270^GLN 192^ASN 172^PHE	0.0.0.0
3k4dA beta-glucuronidase	[pdb]	1.58 0.000659	411^ALA 388^HIS 384^THR 350^ASP 390^GLN 425^PHE 424^TYR		carbohydrate metabolic process metabolic process glucuronoside catabolic process		catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds beta-glucuronidase activity protein binding hydrolase activity hydrolase activity
3qfkA uncharacterized protein	[pdb]	1.59 0.000697	192^GLY 233^HIS 250^THR 195^GLU 235^GLN 54^ASN 57^PHE		nucleotide catabolic process		nucleotide binding hydrolase activity hydrolase activity acting on ester bonds
2qf9B putative secreted protein	[pdb]	1.6 0.000738	57^ALA 158^HIS 155^THR 88^ARG 188^GLN 150^TYR 149^TYR	0.0.0.0
2fh1B gelsolin	[pdb]	1.61 0.000824	502^GLY 467^GLN 446^SER 665^ASP 473^GLN 520^TYR 441^PHE	0.0.0.0	apoptosis aging actin polymerization or depolymerization oligodendrocyte development vesicle-mediated transport actin filament polymerization regulation of cell adhesion wound healing tissue regeneration response to ethanol response to cadmium ion phosphatidylinositol-mediated signaling actin filament severing barbed-end actin filament capping response to folic acid actin filament capping	extracellular region extracellular space cytoplasm cytosol cytoskeleton actin cytoskeleton lamellipodium protein complex perinuclear region of cytoplasm	actin binding calcium ion binding protein binding
3nziA citrate synthase serine protease htra1	[pdb]	1.61 0.000869	354^ALA 318^GLN 298^SER 250^ASP 301^GLN 334^ASN 278^PHE		tricarboxylic acid cycle cellular carbohydrate metabolic process regulation of cell growth proteolysis negative regulation of transforming growth factor beta receptor signaling pathway negative regulation of BMP signaling pathway	mitochondrion extracellular region extracellular space extracellular matrix	citrate (Si)-synthase activity transferase activity transferase activity transferring acyl groups acyl groups converted into alkyl on transfer catalytic activity serine-type endopeptidase activity protein binding insulin-like growth factor binding peptidase activity serine-type peptidase activity
1nphA gelsolin	[pdb]	1.62 0.000917	502^GLY 467^GLN 446^SER 665^ASP 473^GLN 520^TYR 441^PHE	0.0.0.0	apoptosis aging actin polymerization or depolymerization oligodendrocyte development vesicle-mediated transport actin filament polymerization regulation of cell adhesion wound healing tissue regeneration response to ethanol response to cadmium ion phosphatidylinositol-mediated signaling actin filament severing response to folic acid actin filament capping	extracellular region extracellular space cytoplasm cytosol cytoskeleton lamellipodium protein complex perinuclear region of cytoplasm	actin binding protein binding
1zovB monomeric sarcosine oxidase	[pdb]	1.62 0.000917	56^GLY 53^HIS 144^SER 60^GLU 69^GLN 254^TYR 244^PHE	1.5.3.1	tetrahydrofolate metabolic process oxidation-reduction process	cytoplasm	sarcosine oxidase activity oxidoreductase activity
1vkpB agmatine iminohydrolase	[pdb]	1.62 0.000917	373^ALA 371^GLN 25^THR 102^ARG 369^GLN 318^ASN 57^PHE	3.5.3.12	polyamine biosynthetic process putrescine biosynthetic process		hydrolase activity agmatine deiminase activity
1xv2A hypothetical protein, similar to alpha-acetolactate decarboxylase	[pdb]	1.63 0.000967	23^ALA 8^HIS 10^THR 30^GLU 207^GLN 213^ASN 216^PHE	0.0.0.0	polyol metabolic process	endoplasmic reticulum membrane	acetolactate decarboxylase activity
1skaA 3-phytase a	[pdb]	1.63 0.000967	376^TRP 23^HIS 22^SER 37^GLU 16^GLN 380^PHE 28^TYR	3.1.3.8		extracellular region	acid phosphatase activity 3-phytase activity hydrolase activity
2g5gX putative lipoprotein	[pdb]	1.63 0.000967	45^GLY 57^GLN 56^SER 80^GLU 122^GLN 247^TYR 261^TYR	0.0.0.0
1hm2A chondroitinase ac	[pdb]	1.63 0.00102	346^GLY 230^GLN 232^SER 366^ARG 224^GLN 267^TYR 268^TYR	4.2.2.5	carbohydrate metabolic process	extracellular region	catalytic activity lyase activity carbon-oxygen lyase activity acting on polysaccharides carbohydrate binding chondroitin AC lyase activity
3decA beta-galactosidase	[pdb]	1.64 0.00102	193^TRP 8^GLN 9^SER 120^GLU 4^GLN 153^TYR 163^TYR	0.0.0.0	carbohydrate metabolic process metabolic process	beta-galactosidase complex	catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds beta-galactosidase activity hydrolase activity hydrolase activity acting on glycosyl bonds
3myvA susd superfamily protein	[pdb]	1.64 0.00108	419^GLY 75^GLN 76^SER 416^GLU 307^GLN 296^ASN 300^TYR	0.0.0.0
2fknD urocanate hydratase	[pdb]	1.65 0.00113	170^GLY 178^GLN 145^THR 198^ARG 139^GLN 321^ASN 319^TYR	4.2.1.49	histidine metabolic process histidine catabolic process	cytoplasm	urocanate hydratase activity lyase activity
2xr1A cleavage and polyadenylation specificity factor 100 kdsubunit	[pdb]	1.66 0.0012	351^GLY 242^HIS 269^THR 603^GLU 248^GLN 324^PHE 310^TYR	0.0.0.0			RNA binding hydrolase activity
3ladB dihydrolipoamide dehydrogenase	[pdb]	1.66 0.00126	463^ALA 458^HIS 454^SER 411^ASP 429^GLN 401^PHE 386^PHE	1.8.1.4	glycolysis cell redox homeostasis oxidation-reduction process	cytoplasm	dihydrolipoyl dehydrogenase activity oxidoreductase activity flavin adenine dinucleotide binding
3ez8A cellulase	[pdb]	1.67 0.00133	451^GLY 459^HIS 465^SER 455^ARG 508^GLN 98^PHE 101^TYR	0.0.0.0	carbohydrate metabolic process metabolic process		catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds cellulase activity hydrolase activity
3q24A dna (5'-d(tpgpcpcptpcpcpcpapgpgpcpaptpcpcpapapapapgpap* apgpcpgpgpapgpcptptpcptptp*c)-3') virion rna polymerase	[pdb]	1.67 0.00133	1011^ALA 821^GLN 820^THR 1017^ARG 914^HOH 990^PHE 987^TYR
1tdhA nei endonuclease viii-like 1	[pdb]	1.67 0.00133	4^GLY 8^HIS 50^SER 235^GLU 12^GLN 79^PHE 77^PHE	4.2.99.18	DNA repair base-excision repair nucleotide-excision repair response to DNA damage stimulus response to oxidative stress metabolic process negative regulation of nuclease activity	nucleus cytoplasm	nucleic acid binding DNA binding damaged DNA binding catalytic activity DNA-(apurinic or apyrimidinic site) lyase activity protein C-terminus binding zinc ion binding hydrolase activity hydrolase activity acting on glycosyl bonds hydrolase activity hydrolyzing N-glycosyl compounds
1f8iD isocitrate lyase	[pdb]	1.67 0.0014	181^TRP 205^HIS 210^THR 230^ASP 203^GLN 163^ASN 165^TYR	4.1.3.1	response to acid glyoxylate cycle tricarboxylic acid cycle metabolic process pathogenesis carboxylic acid metabolic process response to host immune response cellular response to hypoxia maintenance of symbiont tolerance to host environment	cytoplasm cytosol plasma membrane	catalytic activity isocitrate lyase activity lyase activity methylisocitrate lyase activity
1fuiE l-fucose isomerase	[pdb]	1.68 0.00148	106^ALA 128^HIS 94^SER 563^ARG 130^GLN 120^TYR 92^TYR	5.3.1.25	carbohydrate metabolic process monosaccharide metabolic process fucose metabolic process fucose catabolic process D-arabinose catabolic process L-fucose catabolic process	cytoplasm cytosol	protein binding L-fucose isomerase activity arabinose isomerase activity isomerase activity intramolecular oxidoreductase activity interconverting aldoses and ketoses manganese ion binding
1rkxA cdp-glucose-4,6-dehydratase	[pdb]	1.68 0.00148	24^TRP 30^GLN 35^THR 349^GLU 8^GLN 85^PHE 13^PHE	0.0.0.0	metabolic process cellular metabolic process		catalytic activity binding coenzyme binding
2gf3B monomeric sarcosine oxidase	[pdb]	1.68 0.00148	56^GLY 53^HIS 144^SER 60^GLU 69^GLN 254^TYR 244^PHE	1.5.3.1	tetrahydrofolate metabolic process oxidation-reduction process	cytoplasm	sarcosine oxidase activity oxidoreductase activity
2ve0A laccase	[pdb]	1.69 0.00156	257^TRP 215^HIS 216^SER 287^GLU 251^GLN 197^PHE 245^PHE	0.0.0.0
1jk0B ribonucleoside-diphosphate reductase small chain2 ribonucleoside-diphosphate reductase small chain1	[pdb]	1.7 0.00172	176^ALA 107^GLN 105^SER 22^GLU 109^GLN 226^PHE 223^TYR	1.17.4.1	DNA replication deoxyribonucleoside diphosphate metabolic process deoxyribonucleotide biosynthetic process cofactor biosynthetic process oxidation-reduction process DNA replication deoxyribonucleoside diphosphate metabolic process deoxyribonucleotide biosynthetic process oxidation-reduction process	nucleus cytoplasm ribonucleoside-diphosphate reductase complex nucleus cytoplasm ribonucleoside-diphosphate reductase complex	ribonucleoside-diphosphate reductase activity protein binding oxidoreductase activity identical protein binding transition metal ion binding ribonucleoside-diphosphate reductase activity protein binding oxidoreductase activity identical protein binding metal ion binding transition metal ion binding
3mxvL fab fragment of anti-shh 5e1 mouse/human chimera, heavychain fab fragment of anti-shh 5e1 mouse/human chimera, lightchain	[pdb]	1.71 0.00181	93^ALA 89^ILE 34^LEU 1^GLN 6^GLN 31^ASP 50^VAL
3cdzA coagulation factor viii light chain coagulation factor viii heavy chain	[pdb]	1.72 0.00191	643^GLY 311^HIS 268^SER 541^ARG 316^GLN 648^PHE 671^PHE		acute-phase response cell adhesion blood coagulation oxidation-reduction process	extracellular region extracellular space plasma membrane platelet alpha granule lumen	copper ion binding protein binding oxidoreductase activity metal ion binding
2vdzA laccase	[pdb]	1.72 0.00191	257^TRP 215^HIS 216^SER 287^GLU 251^GLN 197^PHE 245^PHE	0.0.0.0
1x87B urocanase protein	[pdb]	1.72 0.00201	392^ALA 138^GLN 137^SER 372^ASP 399^GLN 205^ASN 206^TYR		histidine metabolic process histidine catabolic process	cytoplasm	urocanate hydratase activity lyase activity
2i53A cyclin k	[pdb]	1.72 0.00201	54^ALA 263^GLN 45^THR 191^ASP 264^GLN 82^TYR 87^PHE	0.0.0.0	regulation of cyclin-dependent protein kinase activity transcription from RNA polymerase II promoter cell cycle mitosis cell division		protein binding
3fnbA acylaminoacyl peptidase smu_737	[pdb]	1.73 0.00201	212^ALA 195^GLN 167^THR 140^GLU 304^GLN 237^TYR 232^PHE	0.0.0.0	proteolysis		serine-type endopeptidase activity
3m6vA rrna methylase	[pdb]	1.73 0.00211	94^GLY 91^GLN 89^SER 122^ARG 86^GLN 227^TYR 293^PHE	0.0.0.0	rRNA processing		RNA binding methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity
1eokA endo-beta-n-acetylglucosaminidase f3	[pdb]	1.73 0.00211	214^GLY 211^GLN 187^SER 253^ASP 209^GLN 148^TYR 152^TYR	3.2.1.96	carbohydrate metabolic process metabolic process	extracellular region	catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds hydrolase activity hydrolase activity acting on glycosyl bonds
1g4uS protein tyrosine phosphatase sptp ras-related c3 botulinum toxin substrate 1	[pdb]	1.73 0.00211	347^GLY 322^GLN 321^THR 309^ARG 319^GLN 512^PHE 338^PHE	3.1.3.48	apoptosis cellular component movement inflammatory response cell adhesion cell-matrix adhesion small GTPase mediated signal transduction induction of apoptosis by extracellular signals response to wounding anatomical structure morphogenesis regulation of hydrogen peroxide metabolic process positive regulation of lamellipodium assembly lamellipodium assembly actin filament polymerization ruffle organization positive regulation of Rho protein signal transduction negative regulation of receptor-mediated endocytosis localization within membrane regulation of respiratory burst protein dephosphorylation pathogenesis dephosphorylation	intracellular cytosol plasma membrane membrane melanosome extracellular region host cell cytoplasm	nucleotide binding GTPase activity protein binding GTP binding enzyme binding GTP-dependent protein binding thioesterase binding phosphoprotein phosphatase activity protein tyrosine phosphatase activity GTPase activator activity protein binding hydrolase activity phosphatase activity
3lzkD fumarylacetoacetate hydrolase family protein	[pdb]	1.73 0.00211	257^GLY 80^GLN 117^SER 148^ASP 114^GLN 196^PHE 120^PHE	0.0.0.0	metabolic process		catalytic activity hydrolase activity
2uzzC n-methyl-l-tryptophan oxidase	[pdb]	1.73 0.00222	55^GLY 52^HIS 143^SER 58^GLU 68^GLN 249^TYR 238^PHE	0.0.0.0	oxidation-reduction process		oxidoreductase activity N-methyl-L-amino-acid oxidase activity
3r1jA alpha-ketoglutarate-dependent taurine dioxygenase	[pdb]	1.73 0.00222	95^ALA 99^HIS 100^THR 257^ASP 224^GLN 155^ASN 104^PHE
3k9cB transcriptional regulator, laci family protein	[pdb]	1.74 0.00234	133^GLY 85^HIS 282^SER 114^GLU 81^GLN 251^PHE 279^TYR	0.0.0.0	regulation of transcription	intracellular	DNA binding sequence-specific DNA binding transcription factor activity
1xrhD ureidoglycolate dehydrogenase	[pdb]	1.74 0.00234	91^ALA 265^GLN 138^SER 84^ASP 141^GLN 124^TYR 125^PHE	1.1.1.154	purine base metabolic process metabolic process allantoin assimilation pathway oxidation-reduction process	cytoplasm	ureidoglycolate dehydrogenase activity oxidoreductase activity
3lluA ras-related gtp-binding protein c	[pdb]	1.74 0.00234	68^GLY 178^HIS 218^THR 156^ARG 192^GLN 229^PHE 226^PHE	0.0.0.0	apoptosis small GTPase mediated signal transduction RNA splicing cell growth	nucleus cytoplasm	nucleotide binding magnesium ion binding GTPase activity protein binding GTP binding GDP binding protein heterodimerization activity
1olpA alpha-toxin	[pdb]	1.75 0.00234	94^ALA 126^HIS 52^SER 71^ASP 229^GLN 101^PHE 120^TYR	0.0.0.0			phospholipase C activity zinc ion binding hydrolase activity
1js1Y transcarbamylase	[pdb]	1.75 0.00234	259^GLY 262^GLN 266^THR 254^ARG 223^GLN 271^PHE 270^TYR	2.1.3.9	'de novo' pyrimidine base biosynthetic process cellular amino acid metabolic process arginine biosynthetic process cellular amino acid biosynthetic process	cytoplasm	aspartate carbamoyltransferase activity amino acid binding transferase activity carboxyl- or carbamoyltransferase activity N-acetylornithine carbamoyltransferase activity
2o2kB methionine synthase	[pdb]	1.75 0.00246	1035^TRP 1038^GLN 1039^SER 1049^GLU 1054^GLN 1062^PHE 1063^TYR	2.1.1.13	protein methylation nervous system development cellular amino acid biosynthetic process methionine biosynthetic process pteridine-containing compound metabolic process cellular metabolic process tetrahydrofolate metabolic process homocysteine metabolic process	intracellular soluble fraction cytoplasm cytosol	protein binding folic acid binding methyltransferase activity zinc ion binding methionine synthase activity homocysteine S-methyltransferase activity amino acid binding transferase activity cobalamin binding metal ion binding
1jroD xanthine dehydrogenase, chain a xanthine dehydrogenase, chain b	[pdb]	1.75 0.00246	315^ALA 404^HIS 402^THR 327^GLU 615^GLN 455^PHE 622^PHE	0.0.0.0	oxidation-reduction process oxidation-reduction process		catalytic activity xanthine dehydrogenase activity xanthine oxidase activity electron carrier activity oxidoreductase activity metal ion binding flavin adenine dinucleotide binding iron-sulfur cluster binding 2 iron 2 sulfur cluster binding xanthine dehydrogenase activity xanthine oxidase activity oxidoreductase activity molybdenum ion binding
1e2tC n-hydroxyarylamine o-acetyltransferase	[pdb]	1.75 0.00246	74^GLY 181^GLN 182^SER 77^GLU 179^GLN 188^ASN 189^PHE	2.3.1.118	metabolic process		acyltransferase activity acetyltransferase activity transferase activity N-hydroxyarylamine O-acetyltransferase activity
1lgyA triacylglycerol lipase	[pdb]	1.75 0.00259	25^ALA 144^HIS 174^THR 30^ARG 150^GLN 20^TYR 17^PHE	3.1.1.3	lipid metabolic process lipid catabolic process	extracellular region extracellular space	triglyceride lipase activity hydrolase activity
2o1sD 1-deoxy-d-xylulose-5-phosphate synthase	[pdb]	1.76 0.00259	422^GLY 429^GLN 430^THR 601^ARG 594^GLN 392^TYR 395^PHE	2.2.1.7	ubiquinone biosynthetic process metabolic process isoprenoid biosynthetic process pyridoxine biosynthetic process thiamine biosynthetic process terpenoid biosynthetic process		catalytic activity 1-deoxy-D-xylulose-5-phosphate synthase activity oxidoreductase activity acting on the aldehyde or oxo group of donors
3ce9C glycerol dehydrogenase	[pdb]	1.76 0.00259	273^ALA 269^GLN 167^SER 313^ARG 264^GLN 298^PHE 297^PHE	0.0.0.0	aromatic amino acid family biosynthetic process oxidation-reduction process		3-dehydroquinate synthase activity oxidoreductase activity acting on CH-OH group of donors
1gahA glucoamylase-471	[pdb]	1.76 0.00259	105^GLY 168^GLN 455^SER 176^ASP 216^GLN 161^ASN 458^TYR	3.2.1.3	polysaccharide catabolic process carbohydrate metabolic process polysaccharide metabolic process metabolic process polysaccharide catabolic process carbohydrate metabolic process polysaccharide metabolic process metabolic process		catalytic activity glucan 1,4-alpha-glucosidase activity hydrolase activity hydrolase activity acting on glycosyl bonds carbohydrate binding catalytic activity glucan 1,4-alpha-glucosidase activity hydrolase activity hydrolase activity
1iicA peptide n-myristoyltransferase	[pdb]	1.76 0.00259	451^GLY 287^GLN 165^SER 282^ARG 162^GLN 423^TYR 204^TYR	2.3.1.97	replicative cell aging N-terminal protein myristoylation N-terminal peptidyl-glycine N-myristoylation	cytoplasm cytosol	glycylpeptide N-tetradecanoyltransferase activity acyltransferase activity transferase activity
1warA human purple acid phosphatase	[pdb]	1.76 0.00272	49^GLY 219^HIS 189^SER 91^ASP 150^GLN 215^TYR 234^TYR	3.1.3.2	dephosphorylation response to lipopolysaccharide negative regulation of interleukin-1 beta production negative regulation of interleukin-12 production negative regulation of tumor necrosis factor production negative regulation of superoxide anion generation response to cytokine stimulus negative regulation of nitric oxide biosynthetic process bone resorption negative regulation of inflammatory response defense response to Gram-positive bacterium bone morphogenesis	lysosome cytosol integral to membrane	acid phosphatase activity ferrous iron binding ferric iron binding hydrolase activity metal ion binding
3jxeA tryptophanyl-trna synthetase	[pdb]	1.76 0.00272	132^TRP 154^GLN 156^SER 139^ASP 111^GLN 118^PHE 126^PHE	6.1.1.2	translation tRNA aminoacylation for protein translation tryptophanyl-tRNA aminoacylation	cytoplasm	nucleotide binding aminoacyl-tRNA ligase activity tryptophan-tRNA ligase activity ATP binding ligase activity
1rzoC agglutinin	[pdb]	1.76 0.00272	1103^ALA 1106^HIS 1109^THR 1048^ARG 1005^GLN 1092^PHE 1115^PHE	3.2.2.22	defense response pathogenesis negative regulation of translation		nucleotide binding protein binding sugar binding hydrolase activity rRNA N-glycosylase activity
1c3hC 30 kd adipocyte complement-related proteinprecursor	[pdb]	1.77 0.00272	215^TRP 145^HIS 116^SER 134^ARG 142^GLN 162^TYR 161^TYR	0.0.0.0	response to hypoxia glucose metabolic process fatty acid beta-oxidation response to nutrient response to sucrose stimulus response to glucose stimulus positive regulation of signal transduction positive regulation of protein kinase A signaling cascade negative regulation of macrophage derived foam cell differentiation negative regulation of tumor necrosis factor-mediated signaling pathway positive regulation of cholesterol efflux fatty acid oxidation negative regulation of granulocyte differentiation positive regulation of cellular protein metabolic process negative regulation of tumor necrosis factor production positive regulation of myeloid cell apoptosis adiponectin-mediated signaling pathway negative regulation of heterotypic cell-cell adhesion low-density lipoprotein particle clearance response to tumor necrosis factor response to drug glucose homeostasis positive regulation of I-kappaB kinase/NF-kappaB cascade negative regulation of I-kappaB kinase/NF-kappaB cascade response to ethanol negative regulation of fat cell differentiation negative regulation of macrophage differentiation negative regulation of low-density lipoprotein particle receptor biosynthetic process negative regulation of gluconeogenesis positive regulation of blood pressure positive regulation of fatty acid metabolic process positive regulation of glucose import negative regulation of hormone secretion positive regulation of peptidyl-tyrosine phosphorylation negative regulation of phagocytosis brown fat cell differentiation protein homooligomerization response to glucocorticoid stimulus membrane depolarization membrane hyperpolarization	extracellular region extracellular space endoplasmic reticulum	receptor binding hormone activity protein binding protein homodimerization activity eukaryotic cell surface binding
2eyqB transcription-repair coupling factor	[pdb]	1.77 0.00286	839^ALA 842^HIS 868^THR 852^ARG 844^GLN 814^TYR 816^TYR	0.0.0.0	transcription-coupled nucleotide-excision repair DNA damage recognition DNA repair regulation of transcription		nucleotide binding nucleic acid binding DNA binding damaged DNA binding sequence-specific DNA binding transcription factor activity helicase activity protein binding ATP binding ATP-dependent helicase activity hydrolase activity
1q9fA outer membrane protein x	[pdb]	1.78 0.00301	106^GLY 129^GLN 139^THR 133^ARG 17^GLN 63^TYR 43^PHE	0.0.0.0		plasma membrane cell outer membrane membrane integral to membrane plasma membrane cell outer membrane membrane integral to membrane plasma membrane cell outer membrane membrane integral to membrane plasma membrane cell outer membrane membrane integral to membrane
2hv2C hypothetical protein	[pdb]	1.78 0.00301	348^ALA 355^GLN 362^SER 311^ASP 129^GLN 369^TYR 368^PHE	0.0.0.0	metabolic process		N-acetyltransferase activity
1yifB beta-1,4-xylosidase	[pdb]	1.78 0.00301	202^ALA 263^HIS 250^SER 209^GLU 292^GLN 198^TYR 191^TYR	3.2.1.37	carbohydrate metabolic process metabolic process xylan catabolic process	plasma membrane membrane	hydrolase activity hydrolyzing O-glycosyl compounds xylan 1,4-beta-xylosidase activity hydrolase activity
3l7sA 5-methyltetrahydropteroyltriglutamate--homocysteinemethyltransferase	[pdb]	1.78 0.00301	286^GLY 321^HIS 114^THR 344^ASP 499^GLN 236^TYR 237^PHE	2.1.1.14	cellular amino acid biosynthetic process methionine biosynthetic process		5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity methyltransferase activity zinc ion binding transferase activity metal ion binding
1uteA protein (ii purple acid phosphatase)	[pdb]	1.78 0.00317	51^GLY 221^HIS 191^SER 93^ASP 152^GLN 217^TYR 236^PHE	3.1.3.2	transport ion transport iron ion transport dephosphorylation response to lipopolysaccharide negative regulation of interleukin-1 beta production negative regulation of interleukin-12 production negative regulation of tumor necrosis factor production negative regulation of superoxide anion generation response to cytokine stimulus negative regulation of nitric oxide biosynthetic process bone resorption negative regulation of inflammatory response defense response to Gram-positive bacterium bone morphogenesis	extracellular region lysosome	acid phosphatase activity ferrous iron binding ferric iron binding hydrolase activity metal ion binding
3lu0C dna-directed rna polymerase subunit beta' dna-directed rna polymerase subunit alpha dna-directed rna polymerase subunit beta dna-directed rna polymerase subunit omega	[pdb]	1.78 0.00317	1121^LEU 1116^SER 1115^ILE 1203^ARG 1209^VAL 799^ARG 1231^ARG	2.7.7.6	transcription DNA-dependent transcription	cytoplasm membrane RNA polymerase complex cytoplasm membrane cytoplasm membrane	DNA binding DNA-directed RNA polymerase activity protein binding zinc ion binding transferase activity nucleotidyltransferase activity protein dimerization activity DNA binding DNA-directed RNA polymerase activity transferase activity nucleotidyltransferase activity DNA binding DNA-directed RNA polymerase activity protein binding transferase activity nucleotidyltransferase activity DNA binding DNA-directed RNA polymerase activity protein binding transferase activity nucleotidyltransferase activity ribonucleoside binding
1yydA peroxidase manganese-dependent i	[pdb]	1.78 0.00317	113^ALA 25^GLN 27^THR 122^ARG 22^GLN 89^ASN 353^PHE	1.11.1.13	response to oxidative stress hydrogen peroxide catabolic process lignin catabolic process oxidation-reduction process	extracellular region	peroxidase activity oxidoreductase activity manganese peroxidase activity heme binding metal ion binding
3p0tB uncharacterized protein	[pdb]	1.79 0.00317	68^GLY 37^HIS 29^THR 79^ARG 35^GLN 19^TYR 17^PHE	0.0.0.0			catalytic activity
2gp4A 6-phosphogluconate dehydratase	[pdb]	1.79 0.00332	351^GLY 216^HIS 220^THR 396^ASP 213^GLN 345^ASN 223^PHE	0.0.0.0	metabolic process Entner-Doudoroff pathway		catalytic activity phosphogluconate dehydratase activity
1m53A isomaltulose synthase	[pdb]	1.79 0.00349	152^TRP 149^GLN 98^SER 165^ARG 208^GLN 110^TYR 96^TYR	0.0.0.0	carbohydrate metabolic process		catalytic activity cation binding
3b5qA putative sulfatase yidj	[pdb]	1.79 0.00349	285^GLY 28^GLN 41^THR 302^ASP 36^GLN 249^PHE 252^TYR	0.0.0.0	metabolic process		catalytic activity sulfuric ester hydrolase activity
3e0mB peptide methionine sulfoxide reductase msra/msrb1 short peptide shmaei	[pdb]	1.79 0.00349	268^GLY 266^HIS 264^SER 193^GLU 188^GLN 246^TYR 245^TYR	1.8.4.12, 1.8.4.11	protein metabolic process oxidation-reduction process	plasma membrane membrane	catalytic activity peptide-methionine-(S)-S-oxide reductase activity oxidoreductase activity oxidoreductase activity acting on a sulfur group of donors
2uvaJ fatty acid synthase beta subunits	[pdb]	1.8 0.00349	1171^TRP 1173^HIS 1178^THR 1210^ASP 1162^GLN 1116^PHE 1271^TYR	0.0.0.0
2qi2A cell division protein pelota related protein	[pdb]	1.8 0.00349	196^GLY 144^GLN 158^THR 231^GLU 155^GLN 204^PHE 178^PHE	0.0.0.0	translation	cytoplasm	nuclease activity endonuclease activity hydrolase activity metal ion binding
2dg2A apolipoprotein a-i binding protein	[pdb]	1.8 0.00349	213^ALA 36^GLN 161^SER 238^GLU 40^GLN 90^ASN 158^PHE	0.0.0.0		extracellular region mitochondrion	protein binding
3nkfA caspase-6	[pdb]	1.8 0.00349	122^GLY 161^GLN 211^SER 64^ARG 230^GLN 217^TYR 216^TYR		lens development in camera-type eye acute inflammatory response to non-antigenic stimulus proteolysis apoptosis induction of apoptosis response to heat response to glucose stimulus response to organic substance response to metal ion response to iron ion response to organic nitrogen response to gamma radiation response to estradiol stimulus response to testosterone stimulus response to cytokine stimulus response to hydrogen peroxide positive regulation of apoptosis positive regulation of neuron apoptosis positive regulation of retinal cell programmed cell death	nucleus nucleoplasm cytoplasm cytosol	endopeptidase activity cysteine-type endopeptidase activity protein binding peptidase activity cysteine-type peptidase activity hydrolase activity
1hr6A mitochondrial processing peptidase alpha subunit mitochondrial processing peptidase beta subunit	[pdb]	1.8 0.00366	340^ILE 258^ILE 334^GLY 455^TYR 260^GLU 310^ALA 311^VAL	3.4.24.64	proteolysis protein processing involved in protein targeting to mitochondrion proteolysis protein processing involved in protein targeting to mitochondrion	mitochondrion mitochondrial matrix mitochondrial processing peptidase complex mitochondrion mitochondrial matrix mitochondrial processing peptidase complex	catalytic activity metalloendopeptidase activity protein binding peptidase activity metallopeptidase activity zinc ion binding hydrolase activity metal ion binding catalytic activity metalloendopeptidase activity protein binding peptidase activity metallopeptidase activity zinc ion binding hydrolase activity metal ion binding
1qhwA protein (purple acid phosphatase)	[pdb]	1.81 0.00366	72^GLY 242^HIS 212^SER 114^ASP 173^GLN 238^TYR 257^TYR	3.1.3.2	ossification negative regulation of cell adhesion response to zinc ion response to organic cyclic compound osteoclast differentiation positive regulation of cell migration multicellular organismal response to stress response to L-ascorbic acid bone resorption response to protein stimulus response to cholesterol	extracellular space lysosome integral to membrane	acid phosphatase activity ferrous iron binding ferric iron binding hydrolase activity metal ion binding
3k4qB 3-phytase a	[pdb]	1.81 0.00366	376^TRP 23^HIS 22^SER 37^GLU 16^GLN 380^PHE 28^TYR	3.1.3.8		extracellular region	acid phosphatase activity 3-phytase activity hydrolase activity
2x98A alkaline phosphatase	[pdb]	1.81 0.00384	316^ALA 62^GLN 353^THR 320^GLU 60^GLN 310^ASN 430^PHE	0.0.0.0	metabolic process		catalytic activity alkaline phosphatase activity hydrolase activity phosphatase activity
3dsrA v-type atp synthase beta chain	[pdb]	1.81 0.00384	177^ALA 241^HIS 296^SER 165^ARG 144^GLN 233^TYR 236^TYR		ATP biosynthetic process transport ion transport ATP synthesis coupled proton transport proton transport ATP metabolic process	proton-transporting two-sector ATPase complex proton-transporting two-sector ATPase complex	hydrolase activity acting on acid anhydrides catalyzing transmembrane movement of substances
3gz2A invasin ipab chaperone protein ipgc	[pdb]	1.81 0.00384	75^GLY 81^GLN 110^THR 56^GLU 87^GLN 97^PHE 104^TYR	0.0.0.0	pathogenesis response to stress pathogenesis	extracellular region membrane integral to membrane host cell plasma membrane host cell membrane cytoplasm	protein binding binding
1un2A thiol-disulfide interchange protein	[pdb]	1.81 0.00384	80^ALA 98^GLN 100^THR 73^ASP 65^GLN 55^PHE 60^TYR	0.0.0.0	cell redox homeostasis protein folding cell redox homeostasis cellular response to antibiotic	outer membrane-bounded periplasmic space periplasmic space outer membrane-bounded periplasmic space periplasmic space	protein disulfide oxidoreductase activity protein disulfide isomerase activity protein binding protein disulfide oxidoreductase activity
2b6mB thiol	[pdb]	1.81 0.00403	179^ALA 8^GLN 10^THR 172^ASP 164^GLN 154^PHE 159^TYR	0.0.0.0	protein folding cell redox homeostasis cellular response to antibiotic	outer membrane-bounded periplasmic space periplasmic space	protein disulfide isomerase activity protein binding protein disulfide oxidoreductase activity
1peoA ribonucleoside-diphosphate reductase 2 alphachain	[pdb]	1.82 0.00403	651^ALA 656^HIS 502^THR 685^ARG 536^GLN 493^PHE 497^TYR	1.17.4.1	DNA replication oxidation-reduction process	ribonucleoside-diphosphate reductase complex	nucleotide binding ribonucleoside-diphosphate reductase activity protein binding ATP binding oxidoreductase activity
2ffcA orotidine 5-monophosphate decarboxylase	[pdb]	1.82 0.00403	174^GLY 202^GLN 201^THR 211^GLU 258^GLN 196^ASN 198^TYR	0.0.0.0
2xg6F ompc	[pdb]	1.82 0.00404	127^GLY 124^HIS 117^SER 89^ASP 123^GLN 173^ASN 170^PHE	0.0.0.0	transport ion transport	plasma membrane cell outer membrane membrane integral to membrane pore complex	transporter activity porin activity
3eu8C putative glucoamylase	[pdb]	1.82 0.00404	410^ALA 413^GLN 360^THR 59^GLU 47^GLN 284^TYR 280^PHE	0.0.0.0
1bwzA protein (diaminopimelate epimerase)	[pdb]	1.82 0.00404	191^ALA 159^HIS 154^SER 213^GLU 72^GLN 185^PHE 130^PHE	5.1.1.7	cellular amino acid biosynthetic process lysine biosynthetic process lysine biosynthetic process via diaminopimelate	cytoplasm	diaminopimelate epimerase activity isomerase activity
1so0C aldose 1-epimerase	[pdb]	1.82 0.00404	163^ALA 333^HIS 334^THR 326^ARG 309^GLN 129^PHE 150^TYR	5.1.3.3	carbohydrate metabolic process hexose metabolic process	cytoplasm	catalytic activity aldose 1-epimerase activity isomerase activity carbohydrate binding
1sy7A catalase 1	[pdb]	1.82 0.00404	148^GLY 234^GLN 258^THR 145^ASP 543^GLN 255^PHE 300^PHE	1.11.1.6	response to oxidative stress hydrogen peroxide catabolic process conidium formation oxidation-reduction process	extracellular region cell wall ascospore wall	catalase activity peroxidase activity iron ion binding oxidoreductase activity heme binding metal ion binding
1tedB pks18	[pdb]	1.82 0.00424	52^ALA 49^GLN 79^THR 58^GLU 74^GLN 224^PHE 344^PHE	0.0.0.0	metabolic process biosynthetic process chalcone biosynthetic process		catalytic activity acyltransferase activity transferase activity
1s5oA carnitine acetyltransferase isoform 2	[pdb]	1.83 0.00424	537^ALA 534^GLN 533^SER 561^GLU 413^GLN 544^PHE 545^PHE	2.3.1.7	generation of precursor metabolites and energy lipid metabolic process fatty acid metabolic process transport energy derivation by oxidation of organic compounds fatty acid beta-oxidation using acyl-CoA oxidase	mitochondrion mitochondrial inner membrane peroxisome endoplasmic reticulum membrane	carnitine O-acetyltransferase activity acyltransferase activity transferase activity
3iacA glucuronate isomerase	[pdb]	1.83 0.00424	362^ALA 378^GLN 348^THR 397^GLU 407^GLN 367^ASN 368^PHE	5.3.1.12	glucuronate catabolic process		glucuronate isomerase activity isomerase activity
1y7bA beta-xylosidase, family 43 glycosyl hydrolase	[pdb]	1.83 0.00444	203^ALA 264^HIS 251^SER 210^GLU 293^GLN 199^TYR 192^TYR	0.0.0.0	carbohydrate metabolic process		hydrolase activity hydrolyzing O-glycosyl compounds
3f93B beta-glucosidase	[pdb]	1.83 0.00445	288^GLY 255^GLN 212^THR 17^ARG 196^GLN 246^TYR 216^PHE	0.0.0.0	carbohydrate metabolic process		hydrolase activity
3a5cD v-type atp synthase subunit d v-type atp synthase beta chain v-type atp synthase subunit f v-type atp synthase alpha chain	[pdb]	1.83 0.00445	188^ARG 252^HIS 307^SER 169^ILE 148^LYS 244^TYR 247^PHE	0.0.0.0	ATP biosynthetic process transport ion transport ATP synthesis coupled proton transport proton transport ATP metabolic process ATP biosynthetic process transport ion transport ATP synthesis coupled proton transport proton transport ATP biosynthetic process transport ion transport ATP synthesis coupled proton transport proton transport ATP biosynthetic process transport ion transport ATP synthesis coupled proton transport proton transport ATP metabolic process	proton-transporting two-sector ATPase complex proton-transporting two-sector ATPase complex catalytic domain proton-transporting two-sector ATPase complex catalytic domain proton-transporting two-sector ATPase complex	nucleotide binding ATP binding hydrolase activity hydrolase activity acting on acid anhydrides catalyzing transmembrane movement of substances hydrogen ion transporting ATP synthase activity rotational mechanism proton-transporting ATPase activity rotational mechanism ATPase activity coupled to transmembrane movement of substances proton-transporting ATPase activity
2bfeA 2-oxoisovalerate dehydrogenase beta subunit 2-oxoisovalerate dehydrogenase alpha subunit	[pdb]	1.83 0.00445	116^LYS 149^SER 161^LYS 71^ASN 145^TYR 157^CYS 110^ILE	1.2.4.4	metabolic process branched chain family amino acid catabolic process oxidation-reduction process response to nutrient metabolic process branched chain family amino acid catabolic process response to glucocorticoid stimulus response to cAMP oxidation-reduction process	mitochondrion mitochondrial matrix mitochondrial alpha-ketoglutarate dehydrogenase complex mitochondrion mitochondrial matrix mitochondrial alpha-ketoglutarate dehydrogenase complex	alpha-ketoacid dehydrogenase activity 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity protein binding oxidoreductase activity oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor carboxy-lyase activity metal ion binding catalytic activity alpha-ketoacid dehydrogenase activity 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity protein binding oxidoreductase activity
2pygB poly(beta-d-mannuronate) c5 epimerase 4	[pdb]	1.84 0.00467	174^GLY 196^HIS 220^SER 152^ASP 225^GLN 244^TYR 245^TYR	0.0.0.0	alginic acid biosynthetic process	extracellular region extracellular space	calcium ion binding isomerase activity
3bqjA va387 polypeptide	[pdb]	1.84 0.00467	229^GLY 454^GLN 240^SER 463^GLU 277^GLN 495^TYR 432^PHE	0.0.0.0
1sqgA sun protein	[pdb]	1.84 0.00467	243^ALA 236^GLN 234^SER 266^GLU 231^GLN 372^TYR 423^TYR	0.0.0.0	regulation of transcription DNA-dependent rRNA processing	cytoplasm	RNA binding methyltransferase activity rRNA methyltransferase activity rRNA (cytosine-C5-)-methyltransferase activity transferase activity
2d5wB pentapeptide a peptide abc transporter, peptide-binding protein pentapeptide b	[pdb]	1.84 0.00467	505^GLY 501^GLN 477^SER 457^GLU 499^GLN 508^ASN 511^PHE	0.0.0.0	transport		transporter activity
2w38A sialidase	[pdb]	1.84 0.00467	47^GLY 75^GLN 99^THR 44^GLU 71^GLN 129^PHE 127^TYR	0.0.0.0
3dhbA n-acyl homoserine lactone hydrolase	[pdb]	1.84 0.00467	207^GLY 173^HIS 103^SER 211^GLU 124^GLN 137^TYR 107^PHE	0.0.0.0			hydrolase activity hydrolase activity
1xr7A genome polyprotein	[pdb]	1.84 0.0049	421^TRP 388^HIS 219^SER 426^GLU 379^GLN 457^TYR 460^PHE	3.4.22.29, 3.6.1.15, 3.4.22.28, 2.7.7.48	transcription RNA-dependent proteolysis viral reproduction RNA-protein covalent cross-linking viral genome replication evasion by virus of host immune response	membrane virion viral capsid host cell cytoplasm host cell membrane host cell cytoplasmic vesicle host cell cytoplasmic vesicle membrane	nucleotide binding RNA binding RNA helicase activity catalytic activity RNA-directed RNA polymerase activity cysteine-type endopeptidase activity helicase activity structural molecule activity ATP binding peptidase activity cysteine-type peptidase activity transferase activity nucleotidyltransferase activity hydrolase activity nucleoside-triphosphatase activity
3gvjA endo-n-acetylneuraminidase	[pdb]	1.84 0.0049	552^GLY 527^HIS 528^SER 549^ARG 330^GLN 592^TYR 586^TYR	3.2.1.129	metabolic process metabolic process		hydrolase activity hydrolase activity acting on glycosyl bonds endo-alpha-sialidase activity hydrolase activity hydrolase activity
2q0zX protein pro2281	[pdb]	1.84 0.0049	256^GLY 278^GLN 241^THR 274^ARG 279^GLN 207^TYR 203^PHE	0.0.0.0	cis assembly of pre-catalytic spliceosome mRNA processing visual perception RNA splicing response to stimulus	nucleus spliceosomal complex U5 snRNP	nucleotide binding nucleic acid binding helicase activity protein binding ATP binding ATP-dependent helicase activity hydrolase activity nucleoside-triphosphatase activity
3lvtA glycosyl hydrolase, family 38	[pdb]	1.84 0.0049	731^GLY 712^GLN 688^SER 300^ARG 710^GLN 728^PHE 790^TYR	0.0.0.0	carbohydrate metabolic process mannose metabolic process		catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds alpha-mannosidase activity zinc ion binding mannosidase activity hydrolase activity
1u8xX maltose-6'-phosphate glucosidase	[pdb]	1.85 0.0049	152^ALA 388^GLN 414^SER 344^GLU 387^GLN 265^TYR 268^TYR	3.2.1.122	carbohydrate metabolic process metabolic process		catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds binding hydrolase activity hydrolase activity acting on glycosyl bonds
3pcoC phenylalanyl-trna synthetase, alpha subunit phenylalanyl-trna synthetase, beta chain	[pdb]	1.85 0.0049	151^LEU 169^CYS 171^GLY 197^ALA 208^GLU 248^ALA 250^VAL		translation tRNA aminoacylation for protein translation phenylalanyl-tRNA aminoacylation translation phenylalanyl-tRNA aminoacylation tRNA processing	cytoplasm cytoplasm membrane	tRNA binding nucleotide binding aminoacyl-tRNA ligase activity phenylalanine-tRNA ligase activity ATP binding tRNA binding nucleotide binding magnesium ion binding RNA binding aminoacyl-tRNA ligase activity phenylalanine-tRNA ligase activity protein binding ATP binding ligase activity metal ion binding
2j4cA cholinesterase	[pdb]	1.85 0.0049	471^TRP 481^GLN 489^SER 137^GLU 484^GLN 419^TYR 500^TYR	3.1.1.8	response to nutrient learning choline metabolic process response to drug response to alkaloid cocaine metabolic process negative regulation of synaptic transmission response to glucocorticoid stimulus response to folic acid	extracellular region extracellular space membrane fraction nuclear envelope lumen endoplasmic reticulum endoplasmic reticulum lumen membrane	beta-amyloid binding catalytic activity acetylcholinesterase activity carboxylesterase activity cholinesterase activity hydrolase activity enzyme binding choline binding
1khoA alpha-toxin	[pdb]	1.85 0.00514	94^ALA 126^HIS 52^SER 71^ASP 229^GLN 101^PHE 120^TYR	3.1.4.3	pathogenesis cytolysis hemolysis in other organism	extracellular region	phospholipase C activity zinc ion binding hydrolase activity hydrolase activity acting on ester bonds phosphatidylcholine phospholipase C activity
3f0wA numb-like protein	[pdb]	1.85 0.00514	191^ALA 186^HIS 185^SER 197^GLU 57^GLN 159^TYR 157^PHE	0.0.0.0	multicellular organismal development nervous system development neuroblast proliferation axonogenesis cytokine-mediated signaling pathway protein metabolic process lateral ventricle development neuroblast division in subventricular zone forebrain development adherens junction organization positive regulation of neurogenesis positive regulation of dendrite morphogenesis	cytoplasm	protein binding
1wduB tras1 orf2p	[pdb]	1.85 0.00514	52^ALA 75^GLN 76^SER 92^ASP 99^GLN 125^TYR 126^TYR	0.0.0.0	RNA-dependent DNA replication		nucleic acid binding RNA binding RNA-directed DNA polymerase activity ribonuclease H activity
3kehB glucocerebrosidase	[pdb]	1.85 0.00514	265^GLY 207^GLN 208^THR 300^GLU 200^GLN 213^PHE 212^TYR	3.2.1.45	carbohydrate metabolic process lipid metabolic process sphingolipid metabolic process lysosome organization metabolic process cell death	lysosome lysosomal membrane membrane	catalytic activity glucosylceramidase activity protein binding hydrolase activity hydrolase activity acting on glycosyl bonds
2e4pB biphenyl dioxygenase ferredoxin subunit	[pdb]	1.85 0.00514	6^ALA 19^GLN 51^SER 23^ASP 42^GLN 37^PHE 30^PHE	0.0.0.0	transport aromatic compound catabolic process electron transport chain oxidation-reduction process		oxidoreductase activity metal ion binding iron-sulfur cluster binding 2 iron
3o8kA fascin	[pdb]	1.85 0.00514	1171^TRP 1291^GLN 1275^THR 1174^ASP 1285^GLN 1307^PHE 1314^TYR	0.0.0.0	cell proliferation actin cytoskeleton organization actin filament bundle assembly	cytoplasm actin cytoskeleton filopodium	actin binding protein binding protein binding bridging
2xe1A outer membrane protein c	[pdb]	1.85 0.00514	257^ALA 244^GLN 224^THR 300^GLU 241^GLN 119^ASN 120^PHE	0.0.0.0	transport ion transport detection of virus entry of virus into host cell	plasma membrane cell outer membrane membrane integral to membrane pore complex	transporter activity porin activity
1yy9D cetuximab fab heavy chain epidermal growth factor receptor cetuximab fab light chain	[pdb]	1.85 0.00514	10^GLY 6^GLN 23^THR 154^GLU 111^GLN 80^PHE 79^PHE	0.0.0.0	activation of MAPKK activity cell morphogenesis ossification embryonic placenta development hair follicle development translation protein phosphorylation response to stress response to osmotic stress response to oxidative stress signal transduction cell surface receptor linked signaling pathway transmembrane receptor protein tyrosine kinase signaling pathway epidermal growth factor receptor signaling pathway activation of phospholipase C activity intracellular protein kinase cascade salivary gland morphogenesis circadian rhythm cell proliferation positive regulation of cell proliferation epidermis development cell-cell adhesion cerebral cortex cell migration positive regulation of cell migration positive regulation of cyclin-dependent protein kinase activity involved in G1/S response to lipid positive regulation of catenin import into nucleus regulation of cell proliferation positive regulation of phosphorylation ovulation cycle activation of phospholipase A2 activity by calcium-mediated signaling negative regulation of apoptosis positive regulation of MAP kinase activity tongue development positive regulation of nitric oxide biosynthetic process negative regulation of mitotic cell cycle protein autophosphorylation astrocyte activation positive regulation of smooth muscle cell proliferation neuron projection morphogenesis positive regulation of epithelial cell proliferation regulation of peptidyl-tyrosine phosphorylation regulation of nitric-oxide synthase activity protein insertion into membrane response to calcium ion positive regulation of protein kinase B signaling cascade positive regulation of synaptic transmission glutamatergic morphogenesis of an epithelial fold	extracellular region extracellular space intracellular nucleus cytoplasm endosome plasma membrane membrane integral to membrane basolateral plasma membrane apical plasma membrane endocytic vesicle Shc-EGFR complex AP-2 adaptor complex	nucleotide binding double-stranded DNA binding protein kinase activity MAP/ERK kinase kinase activity protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity receptor signaling protein tyrosine kinase activity signal transducer activity receptor activity transmembrane receptor activity epidermal growth factor receptor activity protein binding ATP binding kinase activity transferase activity protein phosphatase binding identical protein binding protein heterodimerization activity actin filament binding nitric-oxide synthase regulator activity
2of3A zyg-9	[pdb]	1.85 0.00514	733^ALA 636^HIS 633^THR 729^GLU 639^GLN 697^PHE 698^PHE	0.0.0.0	meiotic spindle organization microtubule-based process mitotic spindle organization embryo development ending in birth or egg hatching body morphogenesis oviposition pronuclear migration positive regulation of growth rate hermaphrodite genitalia development microtubule polymerization cell division	spindle pole cytoplasm centrosome	binding protein binding
1n35A 5'-r(pgpgpgpgpg)-3' 5'-r(apupupapgpcpcpcpcp*c)-3' minor core protein lambda 3	[pdb]	1.86 0.00514	683^GLY 536^GLN 539^SER 459^ARG 537^GLN 659^PHE 655^TYR	2.7.7.48	transcription RNA-dependent viral genome replication	virion viral nucleocapsid viral capsid	nucleotide binding RNA binding RNA-directed RNA polymerase activity transferase activity nucleotidyltransferase activity hydrolase activity
1syoA cation-independent mannose 6-phosphate receptor	[pdb]	1.86 0.00539	361^GLY 348^GLN 325^THR 383^GLU 356^GLN 316^PHE 317^TYR	0.0.0.0	transport	membrane fraction nucleus nuclear envelope lumen cytoplasm lysosome lysosomal membrane endosome cell surface membrane integral to membrane endocytic vesicle trans-Golgi network transport vesicle	glycoprotein binding receptor activity transporter activity protein binding insulin-like growth factor binding mannose binding phosphoprotein binding
3qatA malonyl coa-acyl carrier protein transacylase	[pdb]	1.86 0.00539	259^TRP 93^HIS 99^SER 163^ASP 10^GLN 275^PHE 5^PHE	0.0.0.0	fatty acid biosynthetic process metabolic process		catalytic activity [acyl-carrier-protein] S-malonyltransferase activity binding transferase activity
2x4mB coagulase/fibrinolysin	[pdb]	1.86 0.00539	253^GLY 28^HIS 27^SER 273^ASP 42^GLN 169^ASN 139^PHE	3.4.23.48	proteolysis	plasma membrane cell outer membrane membrane integral to membrane	endopeptidase activity aspartic-type endopeptidase activity peptidase activity hydrolase activity
1lp9F beta-2-microglobulin t-cell receptor alpha chain self-peptide p1049 hla class i histocompatibility antigen, a-2alpha chain t-cell receptor beta chain	[pdb]	1.86 0.00539	3^ALA 24^HIS 22^SER 1^GLU 72^GLN 91^PHE 90^TYR	0.0.0.0	antigen processing and presentation of peptide antigen via MHC class I immune response antigen processing and presentation interspecies interaction between organisms positive regulation of T cell mediated cytotoxicity response to molecule of bacterial origin antigen processing and presentation of peptide antigen via MHC class I antigen processing and presentation of exogenous protein antigen via MHC class Ib TAP-dependent immune response response to drug	Golgi membrane membrane integral to membrane early endosome membrane MHC class I protein complex Golgi membrane extracellular region extracellular space plasma membrane external side of plasma membrane early endosome membrane MHC class I protein complex	protein binding protein binding
2h6tA candidapepsin-3	[pdb]	1.86 0.00539	231^ALA 233^GLN 236^SER 211^ASP 206^GLN 298^PHE 252^TYR	3.4.23.24	signal peptide processing proteolysis nitrogen compound metabolic process pathogenesis protein metabolic process protein catabolic process adhesion to host induction by symbiont of defense-related host calcium ion flux	extracellular region	aspartic-type endopeptidase activity peptidase activity hydrolase activity
2e22A xanthan lyase	[pdb]	1.86 0.00539	628^TRP 596^GLN 594^THR 457^ASP 565^GLN 587^TYR 589^PHE	0.0.0.0	carbohydrate metabolic process	extracellular region	catalytic activity lyase activity carbon-oxygen lyase activity acting on polysaccharides
3n58D adenosylhomocysteinase	[pdb]	1.86 0.00539	52^GLY 55^HIS 83^SER 65^GLU 85^GLN 113^TYR 110^TYR	0.0.0.0	one-carbon metabolic process metabolic process	cytoplasm	catalytic activity adenosylhomocysteinase activity binding hydrolase activity
1lnlC hemocyanin	[pdb]	1.86 0.00565	202^ALA 35^GLN 36^SER 138^ARG 26^GLN 73^TYR 250^PHE	0.0.0.0	transport metabolic process oxygen transport	extracellular region extracellular space	oxygen transporter activity oxidoreductase activity metal ion binding
1af7A chemotaxis receptor methyltransferase cher	[pdb]	1.86 0.00565	134^ALA 180^GLN 177^SER 201^GLU 182^GLN 96^PHE 97^PHE	2.1.1.80	chemotaxis		methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity protein-glutamate O-methyltransferase activity transferase activity
2hzhA laccase	[pdb]	1.87 0.00565	104^GLY 242^GLN 425^THR 197^ARG 237^GLN 422^PHE 404^PHE	0.0.0.0	oxidation-reduction process		copper ion binding laccase activity oxidoreductase activity metal ion binding
2uv0E transcriptional activator protein lasr	[pdb]	1.87 0.00565	127^ALA 78^HIS 77^SER 156^ASP 81^GLN 47^TYR 69^TYR	0.0.0.0	two-component signal transduction system (phosphorelay) regulation of transcription DNA-dependent	intracellular	two-component response regulator activity DNA binding sequence-specific DNA binding transcription factor activity sequence-specific DNA binding
3ikmA dna polymerase subunit gamma-1 dna polymerase subunit gamma-2	[pdb]	1.87 0.00565	609^GLY 613^HIS 615^SER 672^GLU 663^GLN 749^PHE 750^PHE	2.7.7.7	DNA metabolic process DNA replication DNA-dependent DNA replication mitochondrial DNA replication base-excision repair gap-filling aging DNA replication DNA-dependent DNA replication DNA repair translation	mitochondrion mitochondrial inner membrane gamma DNA polymerase complex mitochondrial nucleoid mitochondrial chromosome cytoplasm mitochondrion mitochondrial nucleoid	protease binding nucleic acid binding DNA binding DNA-directed DNA polymerase activity exonuclease activity protein binding transferase activity nucleotidyltransferase activity nucleotide binding DNA binding single-stranded DNA binding DNA-directed DNA polymerase activity aminoacyl-tRNA ligase activity glycine-tRNA ligase activity protein binding ATP binding transferase activity nucleotidyltransferase activity identical protein binding
2o08A bh1327 protein	[pdb]	1.87 0.00593	126^ALA 109^HIS 111^THR 44^GLU 104^GLN 150^ASN 179^TYR	0.0.0.0			catalytic activity
2w0cL protein p6 protein 2 major capsid protein p2 protein p3	[pdb]	1.87 0.00593	117^SER 329^GLN 121^ALA 333^GLU 97^ASP 160^ASN 161^TYR	0.0.0.0		membrane integral to membrane virion virion membrane virion membrane virion virion membrane virion viral capsid
3d64A adenosylhomocysteinase	[pdb]	1.87 0.00593	59^GLY 62^HIS 90^SER 72^GLU 92^GLN 120^PHE 117^TYR	3.3.1.1	one-carbon metabolic process metabolic process	cytoplasm	catalytic activity adenosylhomocysteinase activity binding hydrolase activity
3h7lB endoglucanase	[pdb]	1.87 0.00593	137^GLY 162^GLN 150^SER 194^GLU 161^GLN 213^TYR 243^TYR	0.0.0.0	carbohydrate metabolic process		catalytic activity hydrolase activity
1uuqA mannosyl-oligosaccharide glucosidase	[pdb]	1.87 0.00593	170^ALA 136^GLN 138^SER 163^GLU 403^GLN 214^ASN 131^PHE	0.0.0.0	carbohydrate metabolic process		catalytic activity cation binding
2innA phenol hydroxylase component pho phenol hydroxylase component phn phenol hydroxylase component phm phenol hydroxylase component phl	[pdb]	1.88 0.00593	226^MSE 145^THR 150^SER 233^LYS 143^ASP 76^ASN 79^GLU	0.0.0.0	cellular aromatic compound metabolic process cellular aromatic compound metabolic process oxidation-reduction process cellular aromatic compound metabolic process oxidation-reduction process		monooxygenase activity oxidoreductase activity transition metal ion binding oxidoreductase activity oxidoreductase activity acting on paired donors
3fy1A acidic mammalian chitinase	[pdb]	1.88 0.00621	134^GLY 53^HIS 25^THR 177^ARG 89^GLN 56^TYR 27^TYR	3.2.1.14	polysaccharide catabolic process response to acid production of molecular mediator involved in inflammatory response carbohydrate metabolic process chitin metabolic process chitin catabolic process cell wall chitin metabolic process apoptosis inflammatory response immune response digestion metabolic process response to fungus positive regulation of chemokine secretion	extracellular region extracellular space cytoplasm	lysozyme activity catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds chitinase activity sugar binding chitin binding hydrolase activity hydrolase activity acting on glycosyl bonds