The LabelHash Server

Top 150 matches

For each match you can click on the "[pdb]" link to download a PDB file with the matching chain aligned with the motif.
Download a zip file with PDB files for all the matches and the motif itself.

PDB ID		LRMSD / p-value	Matching Residues	EC	Gene Ontology annotations
PDB ID		LRMSD / p-value	Matching Residues	EC	Biological Process	Cellular Component	Molecular Function
1czfB polygalacturonase ii	[pdb]	0.158 3.11e-05	178^ASN 180^ASP 201^ASP 256^ARG 258^LYS 291^TYR	3.2.1.15	carbohydrate metabolic process cellular cell wall organization metabolic process	extracellular region	polygalacturonase activity hydrolase activity hydrolase activity
2iq7C endopolygalacturonase	[pdb]	0.255 6.82e-05	176^ASN 178^ASP 199^ASP 254^ARG 256^LYS 289^TYR	0.0.0.0	carbohydrate metabolic process cellular cell wall organization metabolic process		polygalacturonase activity hydrolase activity hydrolase activity
1nhcF polygalacturonase i	[pdb]	0.274 7.74e-05	184^ASN 186^ASP 207^ASP 262^ARG 264^LYS 297^TYR	3.2.1.15	carbohydrate metabolic process cellular cell wall organization metabolic process	extracellular region	polygalacturonase activity hydrolase activity hydrolase activity
1hg8A endopolygalacturonase	[pdb]	0.489 0.000148	189^ASN 191^ASP 212^ASP 267^ARG 269^LYS 302^TYR	3.2.1.15	carbohydrate metabolic process cellular cell wall organization metabolic process	extracellular region	polygalacturonase activity hydrolase activity hydrolase activity
1ib4A polygalacturonase	[pdb]	0.606 0.000191	157^ASN 159^ASP 180^ASP 235^ARG 237^LYS 270^TYR	3.2.1.15	carbohydrate metabolic process cellular cell wall organization metabolic process	extracellular region	polygalacturonase activity hydrolase activity hydrolase activity
1kccA endopolygalacturonase	[pdb]	0.663 0.000216	151^ASN 153^ASP 173^ASP 226^ARG 228^LYS 262^TYR	0.0.0.0	carbohydrate metabolic process cellular cell wall organization metabolic process		polygalacturonase activity hydrolase activity hydrolase activity
3jurB exo-poly-alpha-d-galacturonosidase	[pdb]	0.769 0.000258	237^ASN 239^ASP 260^ASP 327^ARG 329^LYS 362^TYR	0.0.0.0	carbohydrate metabolic process		polygalacturonase activity
1bheA polygalacturonase	[pdb]	1.02 0.000312	200^ASN 202^ASP 223^ASP 280^ARG 282^LYS 314^TYR	3.2.1.15	carbohydrate metabolic process cellular cell wall organization metabolic process	extracellular region	polygalacturonase activity hydrolase activity hydrolase activity
3oyvA imelysin	[pdb]	1.23 0.000374	324^ASN 322^ASP 326^ASP 302^ARG 271^LYS 276^TYR	0.0.0.0
2uveB exopolygalacturonase	[pdb]	1.23 0.000374	379^ASN 381^ASP 402^ASP 466^ARG 468^LYS 501^TYR	0.0.0.0
1xbfB clostridium acetobutylicum q97kl0	[pdb]	1.37 0.000438	13^ASN 14^ASP 15^ASP 44^HIS 126^LYS 7^TYR	0.0.0.0
1vmhA uncharacterized conserved protein yjbq/upf0047 family,ortholog yugu b.subtilis	[pdb]	1.44 0.000475	13^ASN 14^ASP 15^ASP 44^HIS 126^LYS 7^TYR	0.0.0.0
1d5rA phosphoinositide phosphotase pten	[pdb]	1.53 0.000554	49^ASN 51^ASP 52^ASP 61^HIS 66^LYS 68^TYR	3.1.3.48, 3.1.3.16, 3.1.3.67	regulation of cyclin-dependent protein kinase activity angiogenesis negative regulation of protein phosphorylation regulation of B cell apoptosis protein dephosphorylation lipid metabolic process apoptosis induction of apoptosis nervous system development central nervous system development heart development aging response to nutrient memory cell proliferation negative regulation of cell proliferation response to glucose stimulus response to organic substance response to inorganic substance response to zinc ion regulation of neuron projection development response to organic cyclic compound dephosphorylation cell migration negative regulation of cell migration neuron projection development regulation of protein stability response to estradiol stimulus regulation of myeloid cell apoptosis response to ATP response to drug positive regulation of apoptosis negative regulation of apoptosis endothelial cell migration response to ethanol response to arsenic-containing substance inositol phosphate dephosphorylation phosphatidylinositol dephosphorylation platelet-derived growth factor receptor signaling pathway cardiac muscle tissue development negative regulation of epithelial cell proliferation negative regulation of phagocytosis protein stabilization positive regulation of sequence-specific DNA binding transcription factor activity regulation of cell cycle negative regulation of focal adhesion assembly negative regulation of protein kinase B signaling cascade canonical Wnt receptor signaling pathway prostate gland growth	nucleus cytoplasm mitochondrion cytosol	magnesium ion binding inositol or phosphatidylinositol phosphatase activity phosphatidylinositol-3-phosphatase activity phosphoprotein phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity platelet-derived growth factor receptor binding protein binding protein tyrosine/serine/threonine phosphatase activity lipid binding phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity hydrolase activity phosphatase activity enzyme binding PDZ domain binding inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity
3n5aA synaptotagmin-7	[pdb]	1.59 0.000658	364^ASN 365^ASP 357^ASP 267^ARG 402^LYS 371^TYR	0.0.0.0	plasma membrane repair transport	lysosome synaptic vesicle membrane integral to membrane cell junction synaptic vesicle membrane cytoplasmic vesicle synapse	transporter activity metal ion binding
1kaeA histidinol dehydrogenase	[pdb]	1.62 0.000708	42^ASN 38^ASP 41^ASP 219^ARG 218^LYS 130^TYR	1.1.1.23	histidine biosynthetic process metabolic process cellular amino acid biosynthetic process oxidation-reduction process		histidinol dehydrogenase activity zinc ion binding oxidoreductase activity metal ion binding NAD binding
1ouuD hemoglobin i	[pdb]	1.64 0.000769	102^ASN 99^ASP 101^ASP 144^ARG 86^LYS 85^TYR	0.0.0.0	transport oxygen transport transport oxygen transport	hemoglobin complex hemoglobin complex	oxygen transporter activity iron ion binding oxygen binding heme binding metal ion binding oxygen transporter activity iron ion binding oxygen binding heme binding metal ion binding
1nikA orf yor151c dna-directed rna polymerase i, ii and iii 23 kdapolypeptide dna-directed rna polymerase subunit rpb8 rpb1 dna-directed rna polymerase ii, chain rpb5 dna-directed rna polymerase ii, chain rpb9 dna-directed rna polymerase ii, chain rpb4 dna-directed rna polymerase ii, chain rpb11 dna-directed rna polymerase ii, chain rpb10 dna-directed rna polymerase ii, chain rpb7 dna-directed rna polymerase ii, chain rpb12 dna-directed rna polymerase ii, chain rpb3	[pdb]	1.65 0.000814	439^ASN 440^ASP 438^ASP 399^ASP 368^GLU 465^ASN	2.7.7.6	transcription from RNA polymerase II promoter termination of RNA polymerase II transcription transcription from RNA polymerase II promoter termination of RNA polymerase II transcription transcription from RNA polymerase I promoter transcription from RNA polymerase II promoter transcription from RNA polymerase III promoter transcription DNA-dependent transcription from RNA polymerase II promoter transcription from RNA polymerase III promoter tRNA transcription from RNA polymerase III promoter transcription DNA-dependent transcription from RNA polymerase I promoter transcription from RNA polymerase II promoter transcription from RNA polymerase III promoter DNA repair transcription-coupled nucleotide-excision repair transcription from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter response to DNA damage stimulus transcription from RNA polymerase I promoter transcription from RNA polymerase II promoter transcription from RNA polymerase III promoter tRNA transcription from RNA polymerase III promoter transcription from RNA polymerase II promoter transcription from RNA polymerase I promoter transcription from RNA polymerase II promoter transcription from RNA polymerase III promoter	nucleus nucleoplasm DNA-directed RNA polymerase II core complex nucleus DNA-directed RNA polymerase II core complex nucleus nucleoplasm DNA-directed RNA polymerase II core complex DNA-directed RNA polymerase III complex nucleolus DNA-directed RNA polymerase I complex nucleus nucleoplasm DNA-directed RNA polymerase II core complex DNA-directed RNA polymerase III complex DNA-directed RNA polymerase I complex cytoplasm RNA polymerase complex nucleus nucleoplasm DNA-directed RNA polymerase II core complex DNA-directed RNA polymerase III complex nucleolus DNA-directed RNA polymerase I complex nucleus DNA-directed RNA polymerase II core complex nucleus nucleoplasm DNA-directed RNA polymerase II core complex DNA-directed RNA polymerase III complex DNA-directed RNA polymerase I complex nucleus DNA-directed RNA polymerase II core complex mitochondrion	DNA binding DNA-directed RNA polymerase activity protein binding metal ion binding protein dimerization activity DNA binding DNA-directed RNA polymerase activity protein binding protein dimerization activity DNA binding DNA-directed RNA polymerase activity metal ion binding DNA binding DNA-directed RNA polymerase activity protein binding DNA binding DNA-directed RNA polymerase activity protein binding zinc ion binding metal ion binding nucleic acid binding DNA binding DNA-directed RNA polymerase activity protein binding zinc ion binding transcription regulator activity metal ion binding DNA binding DNA-directed RNA polymerase activity protein binding DNA binding DNA-directed RNA polymerase activity protein binding transferase activity nucleotidyltransferase activity metal ion binding DNA-directed RNA polymerase activity protein binding DNA binding DNA-directed RNA polymerase activity protein binding transferase activity nucleotidyltransferase activity ribonucleoside binding metal ion binding
1cm8A phosphorylated map kinase p38-gamma	[pdb]	1.67 0.000865	158^ASN 171^ASP 153^ASP 142^ARG 139^LYS 135^TYR	2.7.11.24	protein phosphorylation DNA damage induced protein phosphorylation cell cycle cell cycle arrest signal transduction Ras protein signal transduction muscle organ development myoblast differentiation negative regulation of cell cycle	soluble fraction cytoplasm mitochondrion	nucleotide binding magnesium ion binding protein kinase activity protein serine/threonine kinase activity MAP kinase activity protein binding ATP binding kinase activity transferase activity metal ion binding
2j63B ap-endonuclease	[pdb]	1.7 0.000984	337^ASN 411^ASP 335^ASP 204^ARG 169^LYS 200^TYR	0.0.0.0	DNA repair	intracellular	DNA binding DNA-(apurinic or apyrimidinic site) lyase activity nuclease activity endonuclease activity lyase activity
3gebC eyes absent homolog 2	[pdb]	1.7 0.000984	323^ASN 327^ASP 324^ASP 385^ARG 388^LYS 391^TYR	0.0.0.0	DNA repair protein dephosphorylation apoptosis response to DNA damage stimulus multicellular organismal development mesodermal cell fate specification metabolic process chromatin modification histone dephosphorylation	nucleus cytoplasm	magnesium ion binding catalytic activity phosphoprotein phosphatase activity protein tyrosine phosphatase activity protein binding hydrolase activity metal ion binding
3ikmA dna polymerase subunit gamma-1 dna polymerase subunit gamma-2	[pdb]	1.71 0.00102	740^ASN 743^ASP 741^ASP 618^HIS 751^LYS 732^TYR	2.7.7.7	DNA metabolic process DNA replication DNA-dependent DNA replication mitochondrial DNA replication base-excision repair gap-filling aging DNA replication DNA-dependent DNA replication DNA repair translation	mitochondrion mitochondrial inner membrane gamma DNA polymerase complex mitochondrial nucleoid mitochondrial chromosome cytoplasm mitochondrion mitochondrial nucleoid	protease binding nucleic acid binding DNA binding DNA-directed DNA polymerase activity exonuclease activity protein binding transferase activity nucleotidyltransferase activity nucleotide binding DNA binding single-stranded DNA binding DNA-directed DNA polymerase activity aminoacyl-tRNA ligase activity glycine-tRNA ligase activity protein binding ATP binding transferase activity nucleotidyltransferase activity identical protein binding
1q7fA brain tumor cg10719-pa	[pdb]	1.71 0.00105	792^ASN 808^ASP 793^ASP 1023^ARG 769^LYS 766^TYR		regulation of translation phagocytosis engulfment ganglion mother cell fate determination neuroblast proliferation negative regulation of neuroblast proliferation axon guidance brain development negative regulation of cell proliferation asymmetric cell division rRNA transcription neuron differentiation segmentation oogenesis	intracellular cytoplasm apical cortex basal cortex	protein binding zinc ion binding translation repressor activity translation regulator activity metal ion binding
1lp4A protein kinase ck2	[pdb]	1.72 0.00113	161^ASN 175^ASP 156^ASP 148^HIS 142^LYS 138^TYR	2.7.11.1	protein phosphorylation		nucleotide binding protein kinase activity protein serine/threonine kinase activity ATP binding kinase activity transferase activity
1bxcD xylose isomerase	[pdb]	1.73 0.00113	246^ASN 244^ASP 286^ASP 48^HIS 5^LYS 2^TYR	5.3.1.5	carbohydrate metabolic process pentose-phosphate shunt D-xylose metabolic process	cytoplasm	xylose isomerase activity isomerase activity metal ion binding
2vagA dual specificity protein kinase clk1	[pdb]	1.73 0.00113	293^ASN 325^ASP 288^ASP 280^HIS 274^LYS 270^TYR	2.7.12.1	protein phosphorylation cell proliferation peptidyl-serine phosphorylation peptidyl-threonine phosphorylation peptidyl-tyrosine phosphorylation protein autophosphorylation	nucleus	nucleotide binding protein kinase activity protein serine/threonine kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity ATP binding kinase activity transferase activity
3er8C cap-specific mrna (nucleoside-2'-o-)-methyltransferase rna/dna chimera 5'-r(pupup)d(c)-3' rna/dna chimera 5'-d(cpcp)r(upup)d(c)-3' rna/dna chimera 5'-d(pcp)r(upu)-3' poly(a) polymerase catalytic subunit	[pdb]	1.73 0.00117	249^ASN 245^ASP 248^ASP 467^HIS 233^LYS 240^TYR	2.7.7.19	mRNA processing mRNA capping mRNA processing viral transcription regulation of mRNA 3'-end processing		nucleotide binding polynucleotide adenylyltransferase activity ATP binding transferase activity mRNA (nucleoside-2'-O-)-methyltransferase activity methyltransferase activity transferase activity
3aivA beta-glucosidase	[pdb]	1.74 0.00121	353^ASN 355^ASP 356^ASP 341^HIS 340^LYS 266^TYR		carbohydrate metabolic process metabolic process		catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds beta-glucosidase activity hydrolase activity hydrolase activity
3ofmA casein kinase ii subunit alpha'	[pdb]	1.74 0.00121	162^ASN 176^ASP 157^ASP 149^HIS 143^LYS 139^TYR	2.7.11.1	protein phosphorylation Wnt receptor signaling pathway regulation of cell cycle		nucleotide binding protein kinase activity protein serine/threonine kinase activity protein binding ATP binding kinase activity transferase activity protein N-terminus binding
3aisA beta-glucosidase	[pdb]	1.75 0.00125	353^ASN 355^ASP 356^ASP 341^HIS 340^LYS 266^TYR		carbohydrate metabolic process metabolic process		catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds beta-glucosidase activity hydrolase activity hydrolase activity
2ww8A cell wall surface anchor family protein	[pdb]	1.75 0.00129	198^ASN 200^ASP 201^ASP 722^ARG 690^LYS 692^TYR	0.0.0.0			binding
2dxlB phosphohydrolase	[pdb]	1.77 0.00134	80^ASN 50^ASP 82^ASP 12^ARG 17^LYS 19^TYR	0.0.0.0			hydrolase activity
1hgxA hypoxanthine-guanine-xanthinephosphoribosyltransferase	[pdb]	1.77 0.00139	16^ASN 18^ASP 19^ASP 25^ARG 58^LYS 53^TYR	0.0.0.0	purine ribonucleoside salvage nucleoside metabolic process	cytoplasm	hypoxanthine phosphoribosyltransferase activity transferase activity transferase activity transferring glycosyl groups
2icrA red fluorescent protein zoanrfp	[pdb]	1.77 0.00139	36^ASN 11^ASP 10^ASP 6^HIS 84^LYS 82^TYR	0.0.0.0	bioluminescence protein-chromophore linkage
2e6kB transketolase	[pdb]	1.78 0.00144	52^ASN 55^ASP 57^ASP 109^HIS 100^LYS 76^TYR	0.0.0.0	metabolic process		catalytic activity transketolase activity
2w58A primosome component (helicase loader)	[pdb]	1.78 0.00149	137^ASN 139^ASP 138^ASP 167^HIS 174^LYS 176^TYR	0.0.0.0			nucleotide binding helicase activity ATP binding nucleoside-triphosphatase activity
3owlA csnk2a1 protein	[pdb]	1.79 0.00155	161^ASN 175^ASP 156^ASP 148^HIS 142^LYS 138^TYR	0.0.0.0	protein phosphorylation		nucleotide binding protein kinase activity protein serine/threonine kinase activity protein binding ATP binding
1bbjH igg4-kappa b72.3 fab (heavy chain) igg4-kappa b72.3 fab (light chain)	[pdb]	1.81 0.00166	55^ASN 56^ASP 57^ASP 35^HIS 97^LYS 101^TYR	0.0.0.0	immune response	extracellular region membrane fraction	antigen binding
4blcA protein (catalase)	[pdb]	1.82 0.00172	337^ASN 143^ASP 334^ASP 217^HIS 232^LYS 230^TYR	1.11.1.6	response to reactive oxygen species triglyceride metabolic process response to oxidative stress cholesterol metabolic process aerobic respiration UV protection positive regulation of phosphatidylinositol 3-kinase cascade hemoglobin metabolic process negative regulation of NF-kappaB transcription factor activity hydrogen peroxide catabolic process negative regulation of apoptosis positive regulation of NF-kappaB transcription factor activity protein tetramerization positive regulation of cell division oxidation-reduction process	mitochondrion peroxisome peroxisomal membrane	aminoacylase activity catalase activity peroxidase activity iron ion binding oxidoreductase activity oxidoreductase activity acting on peroxide as acceptor heme binding protein homodimerization activity metal ion binding
3f8uC protein disulfide-isomerase a3erp57 tapasin	[pdb]	1.82 0.00178	251^ALA 250^LEU 253^ILE 309^GLU 305^GLY 265^GLU	5.3.4.1	protein import into nucleus protein retention in ER lumen signal transduction positive regulation of apoptosis cell redox homeostasis protein complex assembly retrograde vesicle-mediated transport Golgi to ER immune response antigen processing and presentation of endogenous peptide antigen via MHC class I	endoplasmic reticulum endoplasmic reticulum lumen melanosome Golgi membrane endoplasmic reticulum endoplasmic reticulum membrane microsome membrane integral to membrane MHC class I peptide loading complex TAP complex	protein disulfide isomerase activity cysteine-type endopeptidase activity phospholipase C activity protein binding isomerase activity protein binding peptide antigen-transporting ATPase activity MHC class I protein binding peptide antigen binding TAP1 binding TAP2 binding unfolded protein binding
1ohfB nudaurelia capensis omega virus capsid protein	[pdb]	1.83 0.00184	547^ASN 83^ASP 85^ASP 106^ARG 94^LYS 242^TYR	0.0.0.0
1olpA alpha-toxin	[pdb]	1.83 0.00191	77^ASN 92^ASP 67^ASP 99^ARG 190^LYS 195^TYR	0.0.0.0			phospholipase C activity zinc ion binding hydrolase activity
3ebyA beta subunit of a putative aromatic-ring-hydroxylating dioxygenase	[pdb]	1.83 0.00191	19^ASN 17^ASP 16^ASP 132^ARG 143^LYS 44^TYR	0.0.0.0	cellular aromatic compound metabolic process oxidation-reduction process		catalytic activity oxidoreductase activity
3oz6A mitogen-activated protein kinase 1, serine/threonineprotein kinase	[pdb]	1.84 0.00191	139^ASN 152^ASP 134^ASP 126^HIS 120^LYS 116^TYR		protein phosphorylation		nucleotide binding protein kinase activity protein serine/threonine kinase activity MAP kinase activity ATP binding kinase activity transferase activity
2a1aB interferon-induced, double-stranded rna-activated protein kinase eukaryotic translation initiation factor 2 alphasubunit	[pdb]	1.84 0.00198	419^ASN 414^ASP 432^ASP 307^ARG 304^LYS 300^TYR	2.7.11.1	translation protein phosphorylation virus-infected cell apoptosis negative regulation of cell proliferation response to virus endoplasmic reticulum unfolded protein response negative regulation of osteoblast proliferation interspecies interaction between organisms protein autophosphorylation translation translational initiation	intracellular cytoplasm ribosome eukaryotic translation initiation factor 2 complex multi-eIF complex	nucleotide binding RNA binding double-stranded RNA binding protein kinase activity protein serine/threonine kinase activity eukaryotic translation initiation factor 2alpha kinase activity protein binding ATP binding protein phosphatase type 2A regulator activity kinase activity transferase activity RNA binding translation initiation factor activity
2qg7E ethanolamine kinase pv091845	[pdb]	1.85 0.00205	366^ASN 296^ASP 363^ASP 210^HIS 207^LYS 394^TYR	0.0.0.0			kinase activity
3fi8A choline kinase	[pdb]	1.85 0.00205	320^ASN 288^ASP 317^ASP 213^HIS 211^LYS 357^TYR	0.0.0.0			kinase activity
2xziB extracellular sialidase/neuraminidase, putative	[pdb]	1.86 0.00212	133^ASN 130^ASP 131^ASP 302^ARG 363^LYS 367^TYR	0.0.0.0	metabolic process		exo-alpha-sialidase activity hydrolase activity hydrolase activity
1dghD protein (catalase)	[pdb]	1.86 0.00212	338^ASN 144^ASP 335^ASP 218^HIS 233^LYS 231^TYR	1.11.1.6	response to reactive oxygen species triglyceride metabolic process response to oxidative stress cholesterol metabolic process aerobic respiration UV protection positive regulation of phosphatidylinositol 3-kinase cascade hemoglobin metabolic process negative regulation of NF-kappaB transcription factor activity hydrogen peroxide catabolic process negative regulation of apoptosis positive regulation of NF-kappaB transcription factor activity protein tetramerization positive regulation of cell division oxidation-reduction process	mitochondrion mitochondrial intermembrane space lysosome peroxisome peroxisomal membrane endoplasmic reticulum Golgi apparatus cytosol plasma membrane	aminoacylase activity catalase activity peroxidase activity iron ion binding protein binding oxidoreductase activity oxidoreductase activity acting on peroxide as acceptor heme binding protein homodimerization activity metal ion binding
2ixaA alpha-n-acetylgalactosaminidase	[pdb]	1.86 0.00212	150^ASN 380^ASP 376^ASP 363^HIS 361^LYS 355^TYR	0.0.0.0	metabolic process		catalytic activity binding alpha-N-acetylgalactosaminidase activity oxidoreductase activity hydrolase activity hydrolase activity
2l3wA phycobilisome rod linker polypeptide	[pdb]	1.87 0.00227	113^ASN 111^ASP 109^ASP 65^ARG 67^LYS 30^TYR	0.0.0.0	photosynthesis	phycobilisome
2x5jR d-erythrose-4-phosphate dehydrogenase	[pdb]	1.88 0.00234	284^ASN 286^ASP 312^ASP 13^ARG 45^LYS 46^TYR		glucose metabolic process metabolic process pyridoxine biosynthetic process pyridoxal phosphate biosynthetic process oxidation-reduction process	cytoplasm	catalytic activity glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity binding protein binding oxidoreductase activity erythrose-4-phosphate dehydrogenase activity NAD binding
3h9qD mccb protein microcin c7	[pdb]	1.88 0.00234	195^ASN 196^ASP 199^ASP 229^ARG 225^LYS 258^TYR	0.0.0.0	metabolic process defense response to bacterium		catalytic activity binding
1e5mA beta ketoacyl acyl carrier protein synthase ii	[pdb]	1.88 0.00234	374^ASN 376^ASP 227^ASP 320^ARG 323^LYS 331^TYR	2.3.1.179	fatty acid biosynthetic process metabolic process lipid biosynthetic process biosynthetic process		catalytic activity acyltransferase activity transferase activity transferase activity transferring acyl groups other than amino-acyl groups
1x56A asparaginyl-trna synthetase	[pdb]	1.89 0.00242	339^ASN 340^ASP 337^ASP 374^ARG 370^LYS 368^TYR	6.1.1.22	translation tRNA aminoacylation for protein translation asparaginyl-tRNA aminoacylation aspartyl-tRNA aminoacylation	cytoplasm	nucleotide binding nucleic acid binding aminoacyl-tRNA ligase activity aspartate-tRNA ligase activity asparagine-tRNA ligase activity ATP binding ligase activity
1qnzH gp120 0.5b antibody (light chain) 0.5b antibody (heavy chain)	[pdb]	1.89 0.00251	152^ASN 201^ASP 202^ASP 197^ARG 179^LYS 172^TYR	0.0.0.0		viral envelope	antigen binding antigen binding
3c5iB choline kinase cleaved fragment of n-terminal expression tag	[pdb]	1.89 0.00251	250^ASN 218^ASP 247^ASP 143^HIS 141^LYS 287^TYR	0.0.0.0			kinase activity
2zoqA mitogen-activated protein kinase 3	[pdb]	1.89 0.00251	171^ASN 184^ASP 166^ASP 158^HIS 155^LYS 148^TYR	2.7.11.24	protein phosphorylation response to DNA damage stimulus cell cycle small GTPase mediated signal transduction Ras protein signal transduction organ morphogenesis sensory perception of pain lipopolysaccharide-mediated signaling pathway response to lipopolysaccharide response to exogenous dsRNA interspecies interaction between organisms regulation of sequence-specific DNA binding transcription factor activity cartilage development	nucleus nucleoplasm cytoplasm cytosol microtubule cytoskeleton nucleolus	nucleotide binding phosphotyrosine binding protein kinase activity protein serine/threonine kinase activity MAP kinase activity protein binding ATP binding kinase activity transferase activity transcription regulator activity
2eklA d-3-phosphoglycerate dehydrogenase	[pdb]	1.9 0.0026	81^ASN 80^ASP 83^ASP 90^ARG 70^LYS 47^TYR	0.0.0.0	L-serine biosynthetic process metabolic process oxidation-reduction process		catalytic activity phosphoglycerate dehydrogenase activity binding oxidoreductase activity acting on the CH-OH group of donors NAD or NADP as acceptor
3a9wB ndp-sugar epimerase	[pdb]	1.9 0.0026	50^ASN 52^ASP 55^ASP 102^HIS 100^LYS 151^TYR		metabolic process cellular metabolic process		catalytic activity binding coenzyme binding
2oqhD putative isomerase	[pdb]	1.9 0.0026	199^ASN 224^ASP 197^ASP 297^HIS 273^LYS 91^TYR	0.0.0.0	metabolic process		catalytic activity isomerase activity metal ion binding
1i2dC atp sulfurylase	[pdb]	1.9 0.00268	200^ASN 236^ASP 234^ASP 386^ARG 383^LYS 378^TYR	2.7.7.4	sulfate assimilation cellular amino acid biosynthetic process methionine biosynthetic process cysteine biosynthetic process	cytoplasm	nucleotide binding sulfate adenylyltransferase (ATP) activity ATP binding kinase activity transferase activity transferase activity transferring phosphorus-containing groups
3dj7A serine/threonine kinase 6	[pdb]	1.91 0.00268	274^ASN 287^ASP 269^ASP 293^HIS 263^LYS 259^TYR	2.7.11.1	mitotic cell cycle protein phosphorylation cell cycle mitosis regulation of protein stability response to estradiol stimulus cell division	spindle pole cytoplasm centrosome microtubule organizing center spindle cytoskeleton microtubule spindle microtubule spindle pole centrosome	nucleotide binding protein kinase activity protein serine/threonine kinase activity protein binding ATP binding kinase activity transferase activity protein kinase binding ubiquitin protein ligase binding
1lf9A glucoamylase	[pdb]	1.91 0.00278	333^ASN 331^ASP 332^ASP 227^ARG 182^LYS 187^TYR	0.0.0.0	carbohydrate metabolic process polysaccharide metabolic process metabolic process		catalytic activity glucan 1,4-alpha-glucosidase activity hydrolase activity hydrolase activity acting on glycosyl bonds
2r7oA rna-dependent rna polymerase	[pdb]	1.92 0.00287	633^ASN 520^ASP 631^ASP 457^ARG 242^LYS 326^TYR	2.7.7.48	transcription RNA-dependent	virion viral nucleocapsid	nucleotide binding RNA binding RNA-directed RNA polymerase activity transferase activity nucleotidyltransferase activity
3ktcB xylose isomerase	[pdb]	1.92 0.00287	231^ASN 232^ASP 240^ASP 170^ARG 168^LYS 167^TYR	0.0.0.0	carbohydrate metabolic process pentose-phosphate shunt D-xylose metabolic process	cytoplasm	xylose isomerase activity isomerase activity metal ion binding
2v62B serine/threonine-protein kinase vrk2	[pdb]	1.93 0.00287	27^ASN 23^ASP 22^ASP 117^ARG 61^LYS 44^TYR	2.7.11.1	protein phosphorylation protein autophosphorylation	membrane fraction endoplasmic reticulum membrane integral to membrane	nucleotide binding protein kinase activity protein serine/threonine kinase activity protein binding ATP binding kinase activity transferase activity
3oy7A glycosyltransferase b736l	[pdb]	1.93 0.00297	182^ASN 183^ASP 184^ASP 359^ARG 298^LYS 271^TYR		biosynthetic process
1ftaC fructose-1,6-bisphosphatase	[pdb]	1.93 0.00297	267^ASN 218^ASP 220^ASP 229^ARG 230^LYS 209^TYR	3.1.3.11	carbohydrate metabolic process fructose metabolic process fructose 6-phosphate metabolic process gluconeogenesis cellular response to insulin stimulus	soluble fraction cytosol	fructose-2,6-bisphosphate 2-phosphatase activity protein binding hydrolase activity fructose 1,6-bisphosphate 1-phosphatase activity phosphoric ester hydrolase activity identical protein binding metal ion binding monosaccharide binding
2i6lB mitogen-activated protein kinase 6	[pdb]	1.94 0.00307	157^ASN 171^ASP 152^ASP 144^HIS 141^LYS 134^TYR	2.7.11.24	protein phosphorylation cell cycle signal transduction		nucleotide binding protein kinase activity protein serine/threonine kinase activity MAP kinase activity ATP binding kinase activity transferase activity
1nw1B choline kinase (49.2 kd)	[pdb]	1.94 0.00307	316^ASN 255^ASP 313^ASP 181^HIS 179^LYS 353^TYR	0.0.0.0			kinase activity
1pvwA 3,4-dihydroxy-2-butanone 4-phosphate synthase	[pdb]	1.94 0.00317	192^ASN 190^ASP 189^ASP 201^ARG 200^LYS 20^TYR	4.1.99.12	riboflavin biosynthetic process		3,4-dihydroxy-2-butanone-4-phosphate synthase activity lyase activity metal ion binding
1n8vB chemosensory protein	[pdb]	1.94 0.00317	10^ASN 6^ASP 9^ASP 46^HIS 44^LYS 26^TYR	0.0.0.0
3hamA aminoglycoside phosphotransferase	[pdb]	1.95 0.00317	197^ASN 210^ASP 192^ASP 121^HIS 118^LYS 246^TYR	0.0.0.0			transferase activity
3hv5A mitogen-activated protein kinase 14	[pdb]	1.95 0.00328	155^ASN 168^ASP 150^ASP 142^HIS 139^LYS 132^TYR	2.7.11.24	protein phosphorylation cellular component movement chemotaxis response to stress signal transduction cell surface receptor linked signaling pathway intracellular protein kinase cascade Ras protein signal transduction	nucleus nucleoplasm cytoplasm cytosol	nucleotide binding protein kinase activity protein serine/threonine kinase activity MAP kinase activity MAP kinase kinase activity protein binding ATP binding kinase activity transferase activity
3c9wB mitogen-activated protein kinase 1	[pdb]	1.95 0.00328	152^ASN 165^ASP 147^ASP 139^HIS 136^LYS 129^TYR	2.7.11.24	MAPKKK cascade MAPK import into nucleus protein phosphorylation response to DNA damage stimulus cell cycle signal transduction intracellular protein kinase cascade positive regulation of cell proliferation response to toxin organ morphogenesis sensory perception of pain cytosine metabolic process positive regulation of cell migration lipopolysaccharide-mediated signaling pathway response to lipopolysaccharide response to chemical stimulus response to exogenous dsRNA response to estrogen stimulus negative regulation of cell differentiation positive regulation of translation T cell receptor signaling pathway B cell receptor signaling pathway labyrinthine layer blood vessel development	soluble fraction insoluble fraction nucleus nucleoplasm cytoplasm cytosol microtubule cytoskeleton dendrite cytoplasm axon part perikaryon protein complex	nucleotide binding phosphotyrosine binding protein kinase activity protein serine/threonine kinase activity MAP kinase activity protein binding ATP binding transcription factor binding RNA polymerase II carboxy-terminal domain kinase activity kinase activity transferase activity mitogen-activated protein kinase kinase kinase binding
3k78A major pollen allergen bet v 1-d/h	[pdb]	1.95 0.00328	29^ASN 26^ASP 28^ASP 71^ARG 69^LYS 67^TYR	0.0.0.0	defense response response to biotic stimulus	cytoplasm
2x6tF adp-l-glycero-d-manno-heptose-6-epimerase	[pdb]	1.96 0.00328	32^ASN 52^ASP 31^ASP 74^HIS 98^LYS 94^TYR	0.0.0.0	carbohydrate metabolic process response to stress metabolic process lipopolysaccharide biosynthetic process cellular metabolic process carbohydrate metabolic process response to stress metabolic process cellular metabolic process	cytosol membrane	catalytic activity binding protein binding ADP-glyceromanno-heptose 6-epimerase activity isomerase activity NADP binding coenzyme binding catalytic activity binding ADP-glyceromanno-heptose 6-epimerase activity isomerase activity NADP binding coenzyme binding
1gq2I malic enzyme	[pdb]	1.96 0.00339	92^ASN 90^ASP 31^ASP 196^HIS 194^LYS 558^TYR	1.1.1.40	malate metabolic process metabolic process oxidation-reduction process	cytoplasm	catalytic activity malic enzyme activity malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity binding oxidoreductase activity oxidoreductase activity acting on the CH-OH group of donors NAD or NADP as acceptor
2duoB vesicular integral-membrane protein vip36	[pdb]	1.96 0.00339	234^ASN 229^ASP 232^ASP 207^ARG 119^LYS 87^TYR	0.0.0.0	transport protein transport	Golgi membrane ER-Golgi intermediate compartment Golgi apparatus membrane integral to membrane	sugar binding
2r91A 2-keto-3-deoxy-(6-phospho-)gluconate aldolase	[pdb]	1.96 0.00339	149^ASN 159^ASP 157^ASP 128^ARG 132^LYS 133^TYR	0.0.0.0	metabolic process		catalytic activity lyase activity
2no4B (s)-2-haloacid dehalogenase iva	[pdb]	1.96 0.00339	178^ASN 11^ASP 181^ASP 156^ARG 149^LYS 58^TYR	3.8.1.2	metabolic process		catalytic activity phosphoglycolate phosphatase activity hydrolase activity (S)-2-haloacid dehalogenase activity hydrolase activity
2kp5A putative uncharacterized protein	[pdb]	1.97 0.0035	77^ASN 78^ASP 76^ASP 44^ARG 6^LYS 16^TYR	0.0.0.0	carbohydrate metabolic process cell adhesion	extracellular region	hydrolase activity hydrolyzing O-glycosyl compounds
2x6dA serine/threonine-protein kinase 6	[pdb]	1.97 0.0035	261^ASN 274^ASP 256^ASP 280^HIS 250^LYS 246^TYR	2.7.11.1	mitotic cell cycle protein phosphorylation cell cycle spindle organization mitosis regulation of protein stability response to estradiol stimulus phosphatidylinositol-mediated signaling cell division	spindle pole nucleus cytoplasm centrosome microtubule organizing center spindle cytoskeleton microtubule spindle microtubule spindle pole centrosome	nucleotide binding protein kinase activity protein serine/threonine kinase activity protein binding ATP binding kinase activity transferase activity protein kinase binding ubiquitin protein ligase binding
2x7jD 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase	[pdb]	1.97 0.00362	484^ASN 485^ASP 457^ASP 516^HIS 515^LYS 525^TYR	2.2.1.9	menaquinone biosynthetic process		catalytic activity transferase activity thiamine pyrophosphate binding metal ion binding 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity
3nieB map2 kinase	[pdb]	1.98 0.00374	161^ASN 174^ASP 156^ASP 148^HIS 145^LYS 138^TYR	0.0.0.0	protein phosphorylation		nucleotide binding protein kinase activity protein serine/threonine kinase activity MAP kinase activity ATP binding kinase activity transferase activity
3hgkD effector protein hopab2 protein kinase	[pdb]	1.99 0.00386	169^PHE 164^VAL 182^SER 71^ARG 54^LYS 56^TYR	0.0.0.0	pathogenesis modulation by symbiont of host defense-related programmed cell death modulation by symbiont of RNA levels in host protein phosphorylation	extracellular region	protein binding ligase activity nucleotide binding protein kinase activity protein serine/threonine kinase activity protein binding ATP binding kinase activity
2fgtA two-component system yycf/yycg regulatoryprotein yych	[pdb]	1.99 0.00386	82^ASN 81^ASP 80^ASP 71^HIS 125^LYS 172^TYR	0.0.0.0		plasma membrane membrane integral to membrane	metal ion binding
3okzA putative uncharacterized protein gbs0355	[pdb]	1.99 0.00387	81^ASN 68^ASP 83^ASP 227^ARG 224^LYS 220^TYR	0.0.0.0
3coiA mitogen-activated protein kinase 13	[pdb]	1.99 0.00399	155^ASN 168^ASP 150^ASP 142^HIS 136^LYS 132^TYR	2.7.11.24	protein phosphorylation response to stress cell cycle intracellular protein kinase cascade Ras protein signal transduction	soluble fraction	nucleotide binding protein kinase activity protein serine/threonine kinase activity MAP kinase activity protein binding ATP binding kinase activity transferase activity
1ffyA isoleucyl-trna isoleucyl-trna synthetase	[pdb]	2 0.004	809^ASN 807^ASP 806^ASP 799^ARG 797^LYS 680^TYR	6.1.1.5	translation tRNA aminoacylation for protein translation isoleucyl-tRNA aminoacylation	cytoplasm	nucleotide binding catalytic activity aminoacyl-tRNA ligase activity isoleucine-tRNA ligase activity ATP binding zinc ion binding ligase activity metal ion binding
1fs6A glucosamine-6-phosphate deaminase	[pdb]	2 0.00413	176^ASN 177^ASP 175^ASP 81^HIS 79^LYS 85^TYR	3.5.99.6	carbohydrate metabolic process N-acetylglucosamine metabolic process N-acetylglucosamine catabolic process UDP-N-acetylglucosamine biosynthetic process		glucosamine-6-phosphate deaminase activity hydrolase activity
3lxdA fad-dependent pyridine nucleotide-disulphideoxidoreductase	[pdb]	2 0.00413	291^ASN 295^ASP 292^ASP 395^ARG 372^LYS 367^TYR	0.0.0.0	cell redox homeostasis oxidation-reduction process	cytoplasm	oxidoreductase activity flavin adenine dinucleotide binding
3b95B histone h3 n-terminal peptide euchromatic histone-lysine n-methyltransferase 1	[pdb]	2 0.00413	873^ASN 840^ASP 839^ASP 813^HIS 817^LYS 852^TYR	2.1.1.43	negative regulation of transcription from RNA polymerase II promoter chromatin modification histone methylation	nucleus	methyltransferase activity zinc ion binding transferase activity histone-lysine N-methyltransferase activity metal ion binding
3kx2A pre-mrna-splicing factor atp-dependent rnahelicase prp43	[pdb]	2 0.00413	570^ASN 567^ASP 566^ASP 604^ARG 601^LYS 595^TYR	0.0.0.0	spliceosome disassembly maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA 5.8S rRNA LSU-rRNA) maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA 5.8S rRNA LSU-rRNA) maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA 5.8S rRNA	nucleus mitochondrion 90S preribosome post-mRNA release spliceosomal complex	nucleotide binding nucleic acid binding ATP-dependent RNA helicase activity helicase activity protein binding ATP binding ATP-dependent helicase activity hydrolase activity identical protein binding
1ixkA methyltransferase	[pdb]	2 0.00413	264^ASN 263^ASP 266^ASP 313^ARG 311^LYS 244^TYR	0.0.0.0	rRNA processing		RNA binding methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity
2x8mA choline-binding protein f	[pdb]	2.01 0.00413	12^ASN 11^ASP 9^ASP 21^HIS 22^LYS 25^TYR
1n44A annexin v	[pdb]	2.01 0.00426	65^ASN 66^ASP 62^ASP 48^ARG 84^LYS 89^TYR	0.0.0.0	blood coagulation response to organic substance positive regulation of apoptosis negative regulation of coagulation protein homooligomerization	intracellular cytoplasm plasma membrane intercalated disc sarcolemma cell projection	calcium ion binding protein binding calcium-dependent phospholipid binding receptor tyrosine kinase binding eukaryotic cell surface binding
1wk1A hypothetical protein yk1067a12	[pdb]	2.01 0.00426	43^ASN 41^ASP 40^ASP 131^ARG 129^LYS 33^TYR	0.0.0.0			binding
1y4sB chaperone protein htpg	[pdb]	2.01 0.00426	258^ASN 259^ASP 256^ASP 33^ARG 28^LYS 25^TYR	0.0.0.0	protein folding response to stress response to heat	cytoplasm cytosol plasma membrane membrane	nucleotide binding protein binding ATP binding ATPase activity coupled
3gfoA cobalt import atp-binding protein cbio 1	[pdb]	2.02 0.0044	93^ASN 90^ASP 92^ASP 140^HIS 137^LYS 101^TYR	0.0.0.0	transport ion transport cobalt ion transport	plasma membrane membrane	nucleotide binding ATP binding hydrolase activity ATPase activity nucleoside-triphosphatase activity
1jc9A techylectin-5a	[pdb]	2.02 0.0044	150^ASN 151^ASP 147^ASP 94^ARG 121^LYS 98^TYR	0.0.0.0	signal transduction cell-cell adhesion	extracellular region extracellular space	receptor binding sugar binding metal ion binding
2eixB nadh-cytochrome b5 reductase	[pdb]	2.02 0.0044	194^ASN 197^ASP 196^ASP 65^ARG 118^LYS 120^TYR	0.0.0.0	oxidation-reduction process		oxidoreductase activity
11asB asparagine synthetase	[pdb]	2.02 0.00455	233^ASN 220^ASP 219^ASP 78^ARG 77^LYS 93^TYR	6.3.1.1	translation tRNA aminoacylation for protein translation asparagine biosynthetic process cellular amino acid biosynthetic process	cytoplasm	nucleotide binding aspartate-ammonia ligase activity aminoacyl-tRNA ligase activity protein binding ATP binding ligase activity
3izgF major capsid protein 10a	[pdb]	2.02 0.00455	287^ASN 103^ASP 286^ASP 304^ARG 197^LYS 208^TYR			virion viral capsid
3na5A phosphoglucomutase	[pdb]	2.02 0.00455	501^ASN 476^ASP 500^ASP 481^ARG 496^LYS 518^TYR		carbohydrate metabolic process		magnesium ion binding phosphoglucomutase activity isomerase activity intramolecular transferase activity phosphotransferases
3dniA deoxyribonuclease i	[pdb]	2.03 0.00455	170^ASN 212^ASP 168^ASP 79^ARG 77^LYS 76^TYR	3.1.21.1	DNA catabolic process apoptosis	extracellular region nucleus nuclear envelope	actin binding nuclease activity endonuclease activity deoxyribonuclease I activity deoxyribonuclease activity protein binding hydrolase activity
2d2nB giant hemoglobin, a1(b) globin chain giant hemoglobin, b2(c) globin chain giant hemoglobin, a2(a5) globin chain giant hemoglobin, b1(d) globin chain	[pdb]	2.04 0.0047	126^HIS 127^ILE 125^ALA 12^ILE 11^VAL 18^VAL	0.0.0.0	transport oxygen transport transport oxygen transport transport oxygen transport transport oxygen transport	extracellular region hemoglobin complex extracellular region hemoglobin complex extracellular region hemoglobin complex extracellular region hemoglobin complex	oxygen transporter activity iron ion binding oxygen binding heme binding metal ion binding oxygen transporter activity iron ion binding oxygen binding heme binding metal ion binding oxygen transporter activity iron ion binding oxygen binding heme binding metal ion binding oxygen transporter activity iron ion binding oxygen binding heme binding metal ion binding
2f49B ste5 peptide mitogen-activated protein kinase fus3	[pdb]	2.04 0.00485	142^ASN 155^ASP 137^ASP 129^HIS 126^LYS 119^TYR	2.7.11.24	conjugation pheromone-dependent signal transduction involved in conjugation with cellular fusion invasive growth in response to glucose limitation protein phosphorylation cell cycle cell cycle arrest mitosis negative regulation of transposition RNA-mediated negative regulation of MAPKKK cascade	nucleus cytoplasm mitochondrion periplasmic space mating projection tip	nucleotide binding protein kinase activity protein serine/threonine kinase activity MAP kinase activity protein binding ATP binding kinase activity transferase activity
3nztA glutamate--cysteine ligase	[pdb]	2.04 0.00485	99^ASN 100^ASP 98^ASP 119^ARG 120^LYS 260^TYR	0.0.0.0	glutathione biosynthetic process		nucleotide binding glutamate-cysteine ligase activity ATP binding ligase activity
2xcqA dna gyrase subunit b, dna gyrase subunit a	[pdb]	2.04 0.00485	1153^ASN 1148^ASP 1151^ASP 579^ARG 546^LYS 554^TYR	5.99.1.3	DNA topological change DNA metabolic process DNA topological change regulation of transcription DNA-dependent	chromosome chromosome	nucleotide binding DNA binding DNA topoisomerase activity DNA topoisomerase (ATP-hydrolyzing) activity ATP binding isomerase activity nucleotide binding DNA binding sequence-specific DNA binding transcription factor activity DNA topoisomerase activity DNA topoisomerase (ATP-hydrolyzing) activity ATP binding isomerase activity
2iukA seed lipoxygenase	[pdb]	2.04 0.00485	485^ASN 482^ASP 484^ASP 445^ARG 453^LYS 455^TYR	1.13.11.12	fatty acid biosynthetic process lipid biosynthetic process oxylipin biosynthetic process oxidation-reduction process	cytoplasm	iron ion binding lipoxygenase activity oxidoreductase activity oxidoreductase activity acting on single donors with incorporation of molecular oxygen
2ztgA alanyl-trna synthetase	[pdb]	2.04 0.00485	545^ASN 561^ASP 546^ASP 533^ARG 506^LYS 509^TYR	6.1.1.7	translation alanyl-tRNA aminoacylation tRNA aminoacylation	cytoplasm	tRNA binding nucleotide binding aminoacyl-tRNA editing activity nucleic acid binding RNA binding aminoacyl-tRNA ligase activity alanine-tRNA ligase activity ATP binding ligase activity ligase activity forming aminoacyl-tRNA and related compounds
2ftyB dihydropyrimidinase	[pdb]	2.05 0.00501	318^ASN 320^ASP 321^ASP 374^HIS 373^LYS 362^TYR	3.5.2.2			dihydropyrimidinase activity hydrolase activity hydrolase activity acting on carbon-nitrogen (but not peptide) bonds
3cf4A acetyl-coa decarbonylase/synthase alpha subunit acetyl-coa decarbonylase/synthase epsilonsubunit	[pdb]	2.05 0.00501	58^SER 55^VAL 56^LYS 802^ARG 801^LYS 678^TYR	0.0.0.0	acetyl-CoA metabolic process generation of precursor metabolites and energy oxidation-reduction process methanogenesis	cytoplasm	catalytic activity electron carrier activity nickel ion binding oxidoreductase activity carbon-monoxide dehydrogenase (acceptor) activity iron-sulfur cluster binding 4 iron
2gfiB phytase	[pdb]	2.05 0.00501	416^ASN 420^ASP 417^ASP 392^ARG 382^LYS 383^TYR	0.0.0.0			acid phosphatase activity 3-phytase activity hydrolase activity
2qt3B n-isopropylammelide isopropyl amidohydrolase	[pdb]	2.05 0.00501	11^ASN 46^ASP 22^ASP 29^ARG 364^LYS 357^TYR	3.5.99.4		cytoplasm	hydrolase activity hydrolase activity acting on carbon-nitrogen (but not peptide) bonds
1khoA alpha-toxin	[pdb]	2.05 0.00501	297^ASN 298^ASP 293^ASP 327^ARG 330^LYS 331^TYR	3.1.4.3	pathogenesis cytolysis hemolysis in other organism	extracellular region	phospholipase C activity zinc ion binding hydrolase activity hydrolase activity acting on ester bonds phosphatidylcholine phospholipase C activity
2eaeA alpha-fucosidase	[pdb]	2.05 0.00518	160^ASN 16^ASP 17^ASP 368^ARG 367^LYS 357^TYR	0.0.0.0			catalytic activity
3bkbA proto-oncogene tyrosine-protein kinase fes/fps	[pdb]	2.06 0.00535	688^ASN 701^ASP 683^ASP 706^ARG 677^LYS 673^TYR	2.7.10.2	protein phosphorylation multicellular organismal development cell proliferation peptidyl-tyrosine phosphorylation	cytosol	nucleotide binding protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein binding ATP binding kinase activity transferase activity
1vsy4 proteasome component c11 proteasome component pre2 proteasome component y7 proteasome component pre4 proteasome component y13 proteasome component pre6 proteasome component c5 proteasome activator blm10 proteasome component c1 proteasome component pre3 proteasome component c7-alpha proteasome component pup1 proteasome component pup2 proteasome component pup3 proteasome component pre5	[pdb]	2.06 0.00535	817^ASN 767^ASP 815^ASP 867^ARG 870^LYS 874^TYR	0.0.0.0	proteasomal ubiquitin-independent protein catabolic process proteasomal ubiquitin-dependent protein catabolic process proteolysis involved in cellular protein catabolic process proteasomal ubiquitin-independent protein catabolic process proteasomal ubiquitin-dependent protein catabolic process proteolysis involved in cellular protein catabolic process ubiquitin-dependent protein catabolic process proteasomal ubiquitin-independent protein catabolic process proteasomal ubiquitin-dependent protein catabolic process proteolysis involved in cellular protein catabolic process proteasomal ubiquitin-independent protein catabolic process proteasomal ubiquitin-dependent protein catabolic process proteolysis involved in cellular protein catabolic process proteasomal ubiquitin-independent protein catabolic process proteasomal ubiquitin-dependent protein catabolic process proteolysis involved in cellular protein catabolic process ubiquitin-dependent protein catabolic process proteasomal ubiquitin-independent protein catabolic process proteasomal ubiquitin-dependent protein catabolic process proteolysis involved in cellular protein catabolic process proteasomal ubiquitin-independent protein catabolic process proteasomal ubiquitin-dependent protein catabolic process proteasome assembly proteolysis involved in cellular protein catabolic process ubiquitin-dependent protein catabolic process proteasomal ubiquitin-independent protein catabolic process proteasomal ubiquitin-dependent protein catabolic process proteolysis involved in cellular protein catabolic process ubiquitin-dependent protein catabolic process proteasomal ubiquitin-independent protein catabolic process proteasomal ubiquitin-dependent protein catabolic process proteolysis involved in cellular protein catabolic process proteasome core complex assembly ubiquitin-dependent protein catabolic process proteasomal ubiquitin-independent protein catabolic process proteasomal ubiquitin-dependent protein catabolic process proteolysis involved in cellular protein catabolic process ubiquitin-dependent protein catabolic process proteasomal ubiquitin-independent protein catabolic process proteasomal ubiquitin-dependent protein catabolic process proteolysis involved in cellular protein catabolic process proteasomal ubiquitin-independent protein catabolic process proteasomal ubiquitin-dependent protein catabolic process proteolysis involved in cellular protein catabolic process proteasome core complex assembly protein catabolic process proteasome assembly ubiquitin-dependent protein catabolic process proteasomal ubiquitin-independent protein catabolic process proteasomal ubiquitin-dependent protein catabolic process proteolysis involved in cellular protein catabolic process proteasomal ubiquitin-independent protein catabolic process proteasomal ubiquitin-dependent protein catabolic process proteolysis involved in cellular protein catabolic process	proteasome complex nucleus cytoplasm endoplasmic reticulum membrane proteasome core complex proteasome core complex beta-subunit complex proteasome storage granule proteasome complex nucleus cytoplasm endoplasmic reticulum membrane proteasome core complex proteasome core complex beta-subunit complex proteasome storage granule proteasome complex nucleus cytoplasm mitochondrion proteasome core complex proteasome core complex alpha-subunit complex proteasome storage granule nuclear membrane-endoplasmic reticulum network proteasome complex nucleus cytoplasm endoplasmic reticulum membrane proteasome core complex proteasome core complex beta-subunit complex proteasome storage granule proteasome complex nucleus cytoplasm endoplasmic reticulum membrane proteasome core complex proteasome core complex beta-subunit complex proteasome storage granule proteasome complex nucleus cytoplasm mitochondrion proteasome core complex proteasome core complex alpha-subunit complex proteasome storage granule nuclear membrane-endoplasmic reticulum network proteasome complex nucleus cytoplasm endoplasmic reticulum membrane proteasome core complex proteasome core complex beta-subunit complex proteasome storage granule proteasome complex nucleus cytoplasm mitochondrion proteasome core complex proteasome core complex alpha-subunit complex proteasome storage granule nuclear membrane-endoplasmic reticulum network proteasome complex nucleus cytoplasm mitochondrion proteasome core complex proteasome core complex alpha-subunit complex proteasome storage granule nuclear membrane-endoplasmic reticulum network proteasome complex nucleus cytoplasm mitochondrion proteasome core complex proteasome core complex alpha-subunit complex proteasome storage granule nuclear membrane-endoplasmic reticulum network proteasome complex nucleus cytoplasm mitochondrion proteasome core complex proteasome core complex alpha-subunit complex proteasome storage granule nuclear membrane-endoplasmic reticulum network proteasome complex nucleus cytoplasm endoplasmic reticulum membrane proteasome core complex proteasome core complex beta-subunit complex proteasome storage granule nucleus cytoplasm proteasome complex proteasome core complex proteasome complex nucleus cytoplasm	endopeptidase activity threonine-type endopeptidase activity protein binding peptidase activity hydrolase activity endopeptidase activator activity endopeptidase activity threonine-type endopeptidase activity peptidase activity hydrolase activity endopeptidase activator activity endopeptidase activity threonine-type endopeptidase activity protein binding peptidase activity hydrolase activity endopeptidase activity threonine-type endopeptidase activity peptidase activity hydrolase activity endopeptidase activity threonine-type endopeptidase activity peptidase activity hydrolase activity endopeptidase activity threonine-type endopeptidase activity protein binding peptidase activity hydrolase activity endopeptidase activity threonine-type endopeptidase activity peptidase activity hydrolase activity endopeptidase activity threonine-type endopeptidase activity protein binding peptidase activity hydrolase activity endopeptidase activity threonine-type endopeptidase activity protein binding peptidase activity hydrolase activity endopeptidase activity threonine-type endopeptidase activity protein binding peptidase activity hydrolase activity endopeptidase activity threonine-type endopeptidase activity protein binding peptidase activity hydrolase activity endopeptidase activity threonine-type endopeptidase activity protein binding peptidase activity hydrolase activity binding protein binding endopeptidase activity threonine-type endopeptidase activity peptidase activity hydrolase activity endopeptidase activity threonine-type endopeptidase activity protein binding peptidase activity hydrolase activity
3h9uC adenosylhomocysteinase	[pdb]	2.06 0.00535	136^ASN 133^ASP 129^ASP 72^ARG 116^LYS 123^TYR	0.0.0.0	one-carbon metabolic process metabolic process		catalytic activity adenosylhomocysteinase activity binding hydrolase activity
2d40D putative gentisate 1,2-dioxygenase	[pdb]	2.06 0.00535	132^ASN 218^ASP 135^ASP 281^HIS 301^LYS 47^TYR	0.0.0.0			oxidoreductase activity
2odjA porin d	[pdb]	2.07 0.00553	398^ASN 400^ASP 364^ASP 275^HIS 273^LYS 271^TYR		transport ion transport basic amino acid transport	plasma membrane cell outer membrane membrane integral to membrane integral to cell outer membrane pore complex	peptidase activity serine-type peptidase activity porin activity hydrolase activity
2esmB rho-associated protein kinase 1	[pdb]	2.07 0.00553	203^ASN 160^ASP 202^ASP 84^ARG 105^LYS 150^TYR	2.7.11.1	cytokinesis protein phosphorylation apoptosis cytoskeleton organization leukocyte cell-cell adhesion signal transduction Rho protein signal transduction membrane to membrane docking actin cytoskeleton organization bleb assembly negative regulation of neuron apoptosis leukocyte migration leukocyte tethering or rolling	Golgi membrane intracellular cytoplasm Golgi apparatus centriole cytosol cytoskeleton membrane	nucleotide binding protein kinase activity protein serine/threonine kinase activity protein binding ATP binding kinase activity transferase activity GTP-Rho binding identical protein binding metal ion binding
2c7hA retinoblastoma-binding protein 6, isoform 3	[pdb]	2.07 0.00553	66^ASN 64^ASP 65^ASP 78^ARG 12^LYS 11^TYR		protein ubiquitination	ubiquitin ligase complex nucleus chromosome nucleolus	nucleic acid binding ubiquitin-protein ligase activity protein binding zinc ion binding ligase activity metal ion binding
3hjeA 704aa long hypothetical glycosyltransferase	[pdb]	2.07 0.00553	480^ASN 478^ASP 481^ASP 513^ARG 516^LYS 390^TYR	0.0.0.0	carbohydrate metabolic process		catalytic activity transferase activity cation binding
1h2oA major allergen pru av 1	[pdb]	2.08 0.00572	28^ASN 25^ASP 27^ASP 69^HIS 68^LYS 66^TYR	0.0.0.0	defense response response to biotic stimulus
1spgB hemoglobin	[pdb]	2.08 0.00572	102^ASN 99^ASP 101^ASP 144^ARG 86^LYS 85^TYR	0.0.0.0	transport oxygen transport transport oxygen transport	hemoglobin complex hemoglobin complex	oxygen transporter activity iron ion binding oxygen binding heme binding metal ion binding oxygen transporter activity iron ion binding oxygen binding heme binding metal ion binding
3mh6A protease do	[pdb]	2.08 0.0059	104^ASN 135^ASP 131^ASP 262^ARG 261^LYS 257^TYR	0.0.0.0	protein folding proteolysis misfolded or incompletely synthesized protein catabolic process response to stress response to oxidative stress response to temperature stimulus	outer membrane-bounded periplasmic space periplasmic space	catalytic activity serine-type endopeptidase activity protein binding peptidase activity serine-type peptidase activity hydrolase activity
3l23A sugar phosphate isomerase/epimerase	[pdb]	2.09 0.00591	178^ASN 236^ASP 238^ASP 268^ARG 270^LYS 155^TYR	0.0.0.0			isomerase activity
2p3yA hypothetical protein vpa0735	[pdb]	2.09 0.0061	373^ASN 371^ASP 369^ASP 384^HIS 382^LYS 435^TYR	0.0.0.0
2r0tB pyridoxamine 5-phosphate-dependent dehydrase	[pdb]	2.09 0.0061	113^ASN 115^ASP 108^ASP 353^HIS 103^LYS 92^TYR	0.0.0.0			catalytic activity pyridoxal phosphate binding
2vyvD glyceraldehyde-3-phosphate dehydrogenase	[pdb]	2.09 0.0061	284^ASN 286^ASP 312^ASP 13^ARG 44^LYS 45^TYR		glucose metabolic process glycolysis metabolic process oxidation-reduction process glucose metabolic process glycolysis spermatid development metabolic process sperm motility oxidation-reduction process	cytoplasm cytosol membrane acrosomal vesicle cytoplasm microtubule-based flagellum flagellum	catalytic activity glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity binding protein binding glyceraldehyde-3-phosphate dehydrogenase activity oxidoreductase activity NAD binding catalytic activity glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity binding protein binding glyceraldehyde-3-phosphate dehydrogenase activity oxidoreductase activity NAD binding
1gcaA glucose/galactose-binding protein	[pdb]	2.09 0.0061	211^ASN 212^ASP 236^ASP 21^ARG 11^LYS 10^TYR	0.0.0.0	transport chemotaxis carbohydrate transport	periplasmic space
1j70B atp sulphurylase	[pdb]	2.09 0.0061	198^ASN 234^ASP 232^ASP 385^ARG 382^LYS 377^TYR	2.7.7.4	sulfate assimilation methionine metabolic process cellular amino acid biosynthetic process methionine biosynthetic process cysteine biosynthetic process	cytoplasm mitochondrion	nucleotide binding sulfate adenylyltransferase (ATP) activity protein binding ATP binding transferase activity nucleotidyltransferase activity identical protein binding
3cdwA protein 3b rna-directed rna polymerase 3d-pol	[pdb]	2.09 0.0061	298^ASN 329^ASP 238^ASP 174^ARG 159^LYS 157^TYR		transcription RNA-dependent proteolysis viral reproduction RNA-protein covalent cross-linking viral genome replication evasion by virus of host immune response	membrane virion viral capsid host cell cytoplasm host cell membrane host cell cytoplasmic vesicle host cell cytoplasmic vesicle membrane	nucleotide binding RNA binding RNA helicase activity catalytic activity RNA-directed RNA polymerase activity cysteine-type endopeptidase activity helicase activity structural molecule activity ATP binding peptidase activity cysteine-type peptidase activity transferase activity nucleotidyltransferase activity hydrolase activity nucleoside-triphosphatase activity
2fvgA endoglucanase	[pdb]	2.09 0.0063	316^ASN 317^ASP 314^ASP 304^ARG 163^LYS 153^TYR	0.0.0.0
3bcyA protein yer067w	[pdb]	2.1 0.0063	37^ASN 42^ASP 43^ASP 156^HIS 135^LYS 123^TYR	0.0.0.0		nucleus cytoplasm
1v4wD hemoglobin beta chain hemoglobin alpha chain	[pdb]	2.1 0.0063	102^ASN 99^ASP 101^ASP 146^HIS 144^LYS 85^TYR	0.0.0.0	transport oxygen transport transport oxygen transport	hemoglobin complex hemoglobin complex	oxygen transporter activity iron ion binding oxygen binding heme binding metal ion binding oxygen transporter activity iron ion binding oxygen binding heme binding metal ion binding
3o4fG spermidine synthase	[pdb]	2.1 0.0063	239^ASN 240^ASP 215^ASP 206^HIS 208^LYS 175^TYR	0.0.0.0	polyamine biosynthetic process spermidine biosynthetic process	cytosol	catalytic activity spermidine synthase activity transferase activity
1otoA internalin b	[pdb]	2.1 0.0063	158^ASN 156^ASP 178^ASP 219^HIS 217^LYS 214^TYR	0.0.0.0			protein binding
2dq0A seryl-trna synthetase	[pdb]	2.1 0.0063	123^ASN 119^ASP 122^ASP 141^ARG 367^LYS 338^TYR	6.1.1.11	translation tRNA aminoacylation for protein translation seryl-tRNA aminoacylation	cytoplasm	nucleotide binding aminoacyl-tRNA ligase activity serine-tRNA ligase activity ATP binding ligase activity
2k6gA replication factor c subunit 1	[pdb]	2.1 0.0063	477^ASN 471^ASP 473^ASP 423^ARG 427^LYS 433^TYR	0.0.0.0	DNA replication DNA-dependent DNA replication nucleotide-excision repair DNA gap filling	intracellular nucleus nucleoplasm DNA replication factor C complex	nucleotide binding DNA binding DNA clamp loader activity protein binding ATP binding enzyme activator activity nucleoside-triphosphatase activity
2xexB elongation factor g	[pdb]	2.1 0.0063	661^ASN 618^ASP 622^ASP 629^ARG 606^LYS 671^TYR	0.0.0.0	translation translational elongation	intracellular cytoplasm	nucleotide binding translation elongation factor activity GTPase activity GTP binding
2gbpA d-galactose/d-glucose binding protein	[pdb]	2.1 0.00651	211^ASN 212^ASP 236^ASP 21^ARG 11^LYS 10^TYR	0.0.0.0	transport chemotaxis carbohydrate transport transport chemotaxis carbohydrate transport transport chemotaxis carbohydrate transport	periplasmic space periplasmic space periplasmic space
1e8cA udp-n-acetylmuramoylalanyl-d-glutamate--2,6-diaminopimelate ligase	[pdb]	2.11 0.00651	205^ASN 241^ASP 242^ASP 247^ARG 251^LYS 228^TYR	6.3.2.13	cellular cell wall organization cell cycle regulation of cell shape biosynthetic process peptidoglycan biosynthetic process peptidoglycan-based cell wall biogenesis cell division	cytoplasm	nucleotide binding protein binding ATP binding UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity ligase activity acid-amino acid ligase activity UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase activity
1pvlA leucocidin	[pdb]	2.11 0.00651	83^ASN 154^ASP 165^ASP 181^ARG 267^LYS 77^TYR	0.0.0.0	pathogenesis cytolysis in other organism	extracellular region
3h2aB dihydropteroate synthase	[pdb]	2.11 0.00651	120^ASN 101^ASP 61^ASP 53^ARG 95^LYS 12^TYR	0.0.0.0	folic acid-containing compound biosynthetic process pteridine-containing compound metabolic process cellular metabolic process folic acid-containing compound biosynthetic process pteridine-containing compound metabolic process cellular metabolic process		dihydropteroate synthase activity transferase activity dihydropteroate synthase activity transferase activity
7ptdA phosphatidylinositol-specific phospholipase c	[pdb]	2.11 0.00651	76^ASN 75^ASP 74^ASP 81^HIS 115^LYS 164^TYR	4.6.1.13	lipid metabolic process lipid catabolic process	extracellular region	phosphatidylinositol diacylglycerol-lyase activity phospholipase C activity phosphoric diester hydrolase activity lyase activity
3dwoX probable outer membrane protein	[pdb]	2.11 0.00673	198^ASN 76^ASP 250^ASP 133^ARG 131^LYS 63^TYR	0.0.0.0		cell outer membrane integral to membrane