The LabelHash Server

1.  1dwwA

LRMSD: 0.0
p-value: 3.70819748241e-06
Matching residues: CYS194 VAL346 TRP366 TYR367 GLU371 ASP376
EC class: 1.14.13.39
GO terms:
Molecular function: protein binding, calmodulin binding, metal ion binding, oxidoreductase activity, zinc ion binding, iron ion binding, nitric-oxide synthase activity, protein homodimerization activity, NADP or NADPH binding, FAD binding, heme binding, FMN binding, electron carrier activity, cAMP-dependent protein kinase regulator activity, tetrahydrobiopterin binding, arginine binding
Biological process: defense response to bacterium, superoxide metabolic process, inflammatory response, oxidation reduction, regulation of cell proliferation, nitric oxide biosynthetic process, response to hypoxia, ovulation from ovarian follicle, defense response to Gram-negative bacterium, retinoic acid receptor signaling pathway, regulation of blood pressure, regulation of heart contraction, protein kinase cascade, G-protein signaling, coupled to cGMP nucleotide second messenger, signal transduction, blood vessel remodeling, endothelial cell proliferation, arginine catabolic process
Cellular component: cytosol, perinuclear region of cytoplasm, cortical cytoskeleton, cytoplasm, peroxisome, nucleus

2.  1dwwB

LRMSD: 0.0973743572831
p-value: 1.49505121954e-05
Matching residues: CYS194 VAL346 TRP366 TYR367 GLU371 ASP376
EC class: 1.14.13.39
GO terms:
Molecular function: protein binding, calmodulin binding, metal ion binding, oxidoreductase activity, zinc ion binding, iron ion binding, nitric-oxide synthase activity, protein homodimerization activity, NADP or NADPH binding, FAD binding, heme binding, FMN binding, electron carrier activity, cAMP-dependent protein kinase regulator activity, tetrahydrobiopterin binding, arginine binding
Biological process: defense response to bacterium, superoxide metabolic process, inflammatory response, oxidation reduction, regulation of cell proliferation, nitric oxide biosynthetic process, response to hypoxia, ovulation from ovarian follicle, defense response to Gram-negative bacterium, retinoic acid receptor signaling pathway, regulation of blood pressure, regulation of heart contraction, protein kinase cascade, G-protein signaling, coupled to cGMP nucleotide second messenger, signal transduction, blood vessel remodeling, endothelial cell proliferation, arginine catabolic process
Cellular component: cytosol, perinuclear region of cytoplasm, cortical cytoskeleton, cytoplasm, peroxisome, nucleus

3.  1dwxA

LRMSD: 0.104378446937
p-value: 1.8554057533e-05
Matching residues: CYS194 VAL346 TRP366 TYR367 GLU371 ASP376
EC class: 1.14.13.39
GO terms:
Molecular function: protein binding, calmodulin binding, metal ion binding, oxidoreductase activity, zinc ion binding, iron ion binding, nitric-oxide synthase activity, protein homodimerization activity, NADP or NADPH binding, FAD binding, heme binding, FMN binding, electron carrier activity, cAMP-dependent protein kinase regulator activity, tetrahydrobiopterin binding, arginine binding
Biological process: defense response to bacterium, superoxide metabolic process, inflammatory response, oxidation reduction, regulation of cell proliferation, nitric oxide biosynthetic process, response to hypoxia, ovulation from ovarian follicle, defense response to Gram-negative bacterium, retinoic acid receptor signaling pathway, regulation of blood pressure, regulation of heart contraction, protein kinase cascade, G-protein signaling, coupled to cGMP nucleotide second messenger, signal transduction, blood vessel remodeling, endothelial cell proliferation, arginine catabolic process
Cellular component: cytosol, perinuclear region of cytoplasm, cortical cytoskeleton, cytoplasm, peroxisome, nucleus

4.  1dwvB

LRMSD: 0.111710488796
p-value: 2.39517939917e-05
Matching residues: CYS194 VAL346 TRP366 TYR367 GLU371 ASP376
EC class: 1.14.13.39
GO terms:
Molecular function: protein binding, calmodulin binding, metal ion binding, oxidoreductase activity, zinc ion binding, iron ion binding, nitric-oxide synthase activity, protein homodimerization activity, NADP or NADPH binding, FAD binding, heme binding, FMN binding, electron carrier activity, cAMP-dependent protein kinase regulator activity, tetrahydrobiopterin binding, arginine binding
Biological process: defense response to bacterium, superoxide metabolic process, inflammatory response, oxidation reduction, regulation of cell proliferation, nitric oxide biosynthetic process, response to hypoxia, ovulation from ovarian follicle, defense response to Gram-negative bacterium, retinoic acid receptor signaling pathway, regulation of blood pressure, regulation of heart contraction, protein kinase cascade, G-protein signaling, coupled to cGMP nucleotide second messenger, signal transduction, blood vessel remodeling, endothelial cell proliferation, arginine catabolic process
Cellular component: cytosol, perinuclear region of cytoplasm, cortical cytoskeleton, cytoplasm, peroxisome, nucleus

5.  1dwxB

LRMSD: 0.145627304912
p-value: 5.01918693772e-05
Matching residues: CYS194 VAL346 TRP366 TYR367 GLU371 ASP376
EC class: 1.14.13.39
GO terms:
Molecular function: protein binding, calmodulin binding, metal ion binding, oxidoreductase activity, zinc ion binding, iron ion binding, nitric-oxide synthase activity, protein homodimerization activity, NADP or NADPH binding, FAD binding, heme binding, FMN binding, electron carrier activity, cAMP-dependent protein kinase regulator activity, tetrahydrobiopterin binding, arginine binding
Biological process: defense response to bacterium, superoxide metabolic process, inflammatory response, oxidation reduction, regulation of cell proliferation, nitric oxide biosynthetic process, response to hypoxia, ovulation from ovarian follicle, defense response to Gram-negative bacterium, retinoic acid receptor signaling pathway, regulation of blood pressure, regulation of heart contraction, protein kinase cascade, G-protein signaling, coupled to cGMP nucleotide second messenger, signal transduction, blood vessel remodeling, endothelial cell proliferation, arginine catabolic process
Cellular component: cytosol, perinuclear region of cytoplasm, cortical cytoskeleton, cytoplasm, peroxisome, nucleus

6.  1fopB

LRMSD: 0.154865920544
p-value: 6.3022467657e-05
Matching residues: CYS186 VAL338 TRP358 TYR359 GLU363 ASN368
EC class: 1.14.13.39
GO terms:
Molecular function: metal ion binding, oxidoreductase activity, zinc ion binding, calmodulin binding, calcium ion binding, iron ion binding, nitric-oxide synthase activity, NADP or NADPH binding, FAD binding, heme binding, FMN binding, electron carrier activity
Biological process: mitochondrion organization, arginine catabolic process, oxidation reduction, blood coagulation, nitric oxide biosynthetic process, positive regulation of guanylate cyclase activity, anti-apoptosis, angiogenesis, ovulation from ovarian follicle, blood vessel remodeling, regulation of sodium ion transport, negative regulation of muscle hyperplasia, smooth muscle hyperplasia, lung development, lipopolysaccharide-mediated signaling pathway, negative regulation of potassium ion transport, positive regulation of angiogenesis, regulation of blood vessel size, negative regulation of hydrolase activity, negative regulation of calcium ion transport
Cellular component: Golgi apparatus, membrane, plasma membrane, cytoskeleton, cytoplasm, caveola

7.  1df1B

LRMSD: 0.161785036325
p-value: 7.74811633164e-05
Matching residues: CYS194 VAL346 TRP366 TYR367 GLU371 ASP376
EC class: 1.14.13.39
GO terms:
Molecular function: protein binding, calmodulin binding, metal ion binding, oxidoreductase activity, zinc ion binding, iron ion binding, nitric-oxide synthase activity, protein homodimerization activity, NADP or NADPH binding, FAD binding, heme binding, FMN binding, electron carrier activity, cAMP-dependent protein kinase regulator activity, tetrahydrobiopterin binding, arginine binding
Biological process: defense response to bacterium, superoxide metabolic process, inflammatory response, oxidation reduction, regulation of cell proliferation, nitric oxide biosynthetic process, response to hypoxia, ovulation from ovarian follicle, defense response to Gram-negative bacterium, retinoic acid receptor signaling pathway, regulation of blood pressure, regulation of heart contraction, protein kinase cascade, G-protein signaling, coupled to cGMP nucleotide second messenger, signal transduction, blood vessel remodeling, endothelial cell proliferation, arginine catabolic process
Cellular component: cytosol, perinuclear region of cytoplasm, cortical cytoskeleton, cytoplasm, peroxisome, nucleus

8.  1n2nA

LRMSD: 0.165810167789
p-value: 7.75789885665e-05
Matching residues: CYS194 VAL346 TRP366 TYR367 GLU371 ASP376
EC class: 1.14.13.39
GO terms:
Molecular function: protein binding, calmodulin binding, metal ion binding, oxidoreductase activity, zinc ion binding, iron ion binding, nitric-oxide synthase activity, protein homodimerization activity, NADP or NADPH binding, FAD binding, heme binding, FMN binding, electron carrier activity, cAMP-dependent protein kinase regulator activity, tetrahydrobiopterin binding, arginine binding
Biological process: defense response to bacterium, superoxide metabolic process, inflammatory response, oxidation reduction, regulation of cell proliferation, nitric oxide biosynthetic process, response to hypoxia, ovulation from ovarian follicle, defense response to Gram-negative bacterium, retinoic acid receptor signaling pathway, regulation of blood pressure, regulation of heart contraction, protein kinase cascade, G-protein signaling, coupled to cGMP nucleotide second messenger, signal transduction, blood vessel remodeling, endothelial cell proliferation, arginine catabolic process
Cellular component: cytosol, perinuclear region of cytoplasm, cortical cytoskeleton, cytoplasm, peroxisome, nucleus

9.  3nodB

LRMSD: 0.168507903814
p-value: 0.000101788362372
Matching residues: CYS194 VAL346 TRP366 TYR367 GLU371 ASP376
EC class: 1.14.13.39
GO terms:
Molecular function: protein binding, calmodulin binding, metal ion binding, oxidoreductase activity, zinc ion binding, iron ion binding, nitric-oxide synthase activity, protein homodimerization activity, NADP or NADPH binding, FAD binding, heme binding, FMN binding, electron carrier activity, cAMP-dependent protein kinase regulator activity, tetrahydrobiopterin binding, arginine binding
Biological process: defense response to bacterium, superoxide metabolic process, inflammatory response, oxidation reduction, regulation of cell proliferation, nitric oxide biosynthetic process, response to hypoxia, ovulation from ovarian follicle, defense response to Gram-negative bacterium, retinoic acid receptor signaling pathway, regulation of blood pressure, regulation of heart contraction, protein kinase cascade, G-protein signaling, coupled to cGMP nucleotide second messenger, signal transduction, blood vessel remodeling, endothelial cell proliferation, arginine catabolic process
Cellular component: cytosol, perinuclear region of cytoplasm, cortical cytoskeleton, cytoplasm, peroxisome, nucleus

10.  1q2oB

LRMSD: 0.169500246644
p-value: 0.000101825156889
Matching residues: CYS186 VAL338 TRP358 TYR359 GLU363 ASP368
EC class: 1.14.13.39
GO terms:
Molecular function: metal ion binding, oxidoreductase activity, zinc ion binding, calmodulin binding, calcium ion binding, iron ion binding, nitric-oxide synthase activity, NADP or NADPH binding, FAD binding, heme binding, FMN binding, electron carrier activity
Biological process: angiogenesis, ovulation from ovarian follicle, blood vessel remodeling, regulation of sodium ion transport, negative regulation of muscle hyperplasia, smooth muscle hyperplasia, lung development, lipopolysaccharide-mediated signaling pathway, negative regulation of potassium ion transport, positive regulation of angiogenesis, regulation of blood vessel size, negative regulation of hydrolase activity, negative regulation of calcium ion transport, oxidation reduction, blood coagulation, nitric oxide biosynthetic process, positive regulation of guanylate cyclase activity, anti-apoptosis, mitochondrion organization, arginine catabolic process
Cellular component: caveola, Golgi apparatus, membrane, plasma membrane, cytoskeleton, cytoplasm

11.  3e6nB

LRMSD: 0.170571863651
p-value: 0.000101864890894
Matching residues: CYS194 VAL346 TRP366 TYR367 GLU371 ASP376
EC class: 1.14.13.39
GO terms:
Molecular function: protein binding, calmodulin binding, metal ion binding, oxidoreductase activity, zinc ion binding, iron ion binding, nitric-oxide synthase activity, protein homodimerization activity, NADP or NADPH binding, FAD binding, heme binding, FMN binding, electron carrier activity, cAMP-dependent protein kinase regulator activity, tetrahydrobiopterin binding, arginine binding
Biological process: defense response to bacterium, superoxide metabolic process, inflammatory response, oxidation reduction, regulation of cell proliferation, nitric oxide biosynthetic process, response to hypoxia, ovulation from ovarian follicle, defense response to Gram-negative bacterium, retinoic acid receptor signaling pathway, regulation of blood pressure, regulation of heart contraction, protein kinase cascade, G-protein signaling, coupled to cGMP nucleotide second messenger, signal transduction, blood vessel remodeling, endothelial cell proliferation, arginine catabolic process
Cellular component: cytosol, perinuclear region of cytoplasm, cortical cytoskeleton, cytoplasm, peroxisome, nucleus

12.  1dwvA

LRMSD: 0.172115698457
p-value: 0.000101922138128
Matching residues: CYS194 VAL346 TRP366 TYR367 GLU371 ASP376
EC class: 1.14.13.39
GO terms:
Molecular function: protein binding, calmodulin binding, metal ion binding, oxidoreductase activity, zinc ion binding, iron ion binding, nitric-oxide synthase activity, protein homodimerization activity, NADP or NADPH binding, FAD binding, heme binding, FMN binding, electron carrier activity, cAMP-dependent protein kinase regulator activity, tetrahydrobiopterin binding, arginine binding
Biological process: defense response to bacterium, superoxide metabolic process, inflammatory response, oxidation reduction, regulation of cell proliferation, nitric oxide biosynthetic process, response to hypoxia, ovulation from ovarian follicle, defense response to Gram-negative bacterium, retinoic acid receptor signaling pathway, regulation of blood pressure, regulation of heart contraction, protein kinase cascade, G-protein signaling, coupled to cGMP nucleotide second messenger, signal transduction, blood vessel remodeling, endothelial cell proliferation, arginine catabolic process
Cellular component: cytosol, perinuclear region of cytoplasm, cortical cytoskeleton, cytoplasm, peroxisome, nucleus

13.  1qw4A

LRMSD: 0.174112394452
p-value: 0.000101996178273
Matching residues: CYS194 VAL346 TRP366 TYR367 GLU371 ASP376
EC class: 1.14.13.39
GO terms:
Molecular function: protein binding, calmodulin binding, metal ion binding, oxidoreductase activity, zinc ion binding, iron ion binding, nitric-oxide synthase activity, protein homodimerization activity, NADP or NADPH binding, FAD binding, heme binding, FMN binding, electron carrier activity, cAMP-dependent protein kinase regulator activity, tetrahydrobiopterin binding, arginine binding
Biological process: defense response to bacterium, superoxide metabolic process, inflammatory response, oxidation reduction, regulation of cell proliferation, nitric oxide biosynthetic process, response to hypoxia, ovulation from ovarian follicle, defense response to Gram-negative bacterium, retinoic acid receptor signaling pathway, regulation of blood pressure, regulation of heart contraction, protein kinase cascade, G-protein signaling, coupled to cGMP nucleotide second messenger, signal transduction, blood vessel remodeling, endothelial cell proliferation, arginine catabolic process
Cellular component: cytosol, perinuclear region of cytoplasm, cortical cytoskeleton, cytoplasm, peroxisome, nucleus

14.  1nsiB

LRMSD: 0.175429433584
p-value: 0.000138878764119
Matching residues: CYS200 VAL352 TRP372 TYR373 GLU377 ASP382
EC class: 1.14.13.39
GO terms:
Molecular function: protein binding, metal ion binding, oxidoreductase activity, zinc ion binding, calmodulin binding, calcium ion binding, iron ion binding, nitric-oxide synthase activity, NADP or NADPH binding, FAD binding, heme binding, FMN binding, electron carrier activity, tetrahydrobiopterin binding, protein homodimerization activity, arginine binding, cAMP-dependent protein kinase regulator activity
Biological process: defense response to bacterium, superoxide metabolic process, oxidation reduction, nitric oxide biosynthetic process, regulation of insulin secretion, arginine catabolic process, defense response to Gram-negative bacterium, innate immune response in mucosa, positive regulation of killing of cells of another organism, regulation of cellular respiration, positive regulation of leukocyte mediated cytotoxicity, response to hypoxia, endothelial cell proliferation, blood vessel remodeling, signal transduction, G-protein signaling, coupled to cGMP nucleotide second messenger, protein kinase cascade, regulation of heart contraction, regulation of blood pressure, regulation of cell proliferation, retinoic acid receptor signaling pathway
Cellular component: nucleus, cytoplasm, cytosol, intracellular, peroxisome, cortical cytoskeleton, perinuclear region of cytoplasm

15.  3dwjB

LRMSD: 0.176230609417
p-value: 0.000138919858728
Matching residues: CYS194 VAL346 TRP366 TYR367 GLU371 ASP376
EC class: 1.14.13.39
GO terms:
Molecular function: protein binding, calmodulin binding, metal ion binding, oxidoreductase activity, zinc ion binding, iron ion binding, nitric-oxide synthase activity, protein homodimerization activity, NADP or NADPH binding, FAD binding, heme binding, FMN binding, electron carrier activity, cAMP-dependent protein kinase regulator activity, tetrahydrobiopterin binding, arginine binding
Biological process: defense response to bacterium, superoxide metabolic process, inflammatory response, oxidation reduction, regulation of cell proliferation, nitric oxide biosynthetic process, response to hypoxia, ovulation from ovarian follicle, defense response to Gram-negative bacterium, retinoic acid receptor signaling pathway, regulation of blood pressure, regulation of heart contraction, protein kinase cascade, G-protein signaling, coupled to cGMP nucleotide second messenger, signal transduction, blood vessel remodeling, endothelial cell proliferation, arginine catabolic process
Cellular component: cytosol, perinuclear region of cytoplasm, cortical cytoskeleton, cytoplasm, peroxisome, nucleus

16.  1r35B

LRMSD: 0.176980271935
p-value: 0.000138958290336
Matching residues: CYS194 VAL346 TRP366 TYR367 GLU371 ASP376
EC class: 1.14.13.39
GO terms:
Molecular function: protein binding, calmodulin binding, metal ion binding, oxidoreductase activity, zinc ion binding, iron ion binding, nitric-oxide synthase activity, protein homodimerization activity, NADP or NADPH binding, FAD binding, heme binding, FMN binding, electron carrier activity, cAMP-dependent protein kinase regulator activity, tetrahydrobiopterin binding, arginine binding
Biological process: defense response to bacterium, superoxide metabolic process, inflammatory response, oxidation reduction, regulation of cell proliferation, nitric oxide biosynthetic process, response to hypoxia, ovulation from ovarian follicle, defense response to Gram-negative bacterium, retinoic acid receptor signaling pathway, regulation of blood pressure, regulation of heart contraction, protein kinase cascade, G-protein signaling, coupled to cGMP nucleotide second messenger, signal transduction, blood vessel remodeling, endothelial cell proliferation, arginine catabolic process
Cellular component: cytosol, perinuclear region of cytoplasm, cortical cytoskeleton, cytoplasm, peroxisome, nucleus

17.  1qw5B

LRMSD: 0.178364187479
p-value: 0.000139029260026
Matching residues: CYS194 VAL346 TRP366 TYR367 GLU371 ASP376
EC class: 1.14.13.39
GO terms:
Molecular function: protein binding, calmodulin binding, metal ion binding, oxidoreductase activity, zinc ion binding, iron ion binding, nitric-oxide synthase activity, protein homodimerization activity, NADP or NADPH binding, FAD binding, heme binding, FMN binding, electron carrier activity, cAMP-dependent protein kinase regulator activity, tetrahydrobiopterin binding, arginine binding
Biological process: defense response to bacterium, superoxide metabolic process, inflammatory response, oxidation reduction, regulation of cell proliferation, nitric oxide biosynthetic process, response to hypoxia, ovulation from ovarian follicle, defense response to Gram-negative bacterium, retinoic acid receptor signaling pathway, regulation of blood pressure, regulation of heart contraction, protein kinase cascade, G-protein signaling, coupled to cGMP nucleotide second messenger, signal transduction, blood vessel remodeling, endothelial cell proliferation, arginine catabolic process
Cellular component: cytosol, perinuclear region of cytoplasm, cortical cytoskeleton, cytoplasm, peroxisome, nucleus

18.  1r35A

LRMSD: 0.178753450513
p-value: 0.000139049225254
Matching residues: CYS194 VAL346 TRP366 TYR367 GLU371 ASP376
EC class: 1.14.13.39
GO terms:
Molecular function: protein binding, calmodulin binding, metal ion binding, oxidoreductase activity, zinc ion binding, iron ion binding, nitric-oxide synthase activity, protein homodimerization activity, NADP or NADPH binding, FAD binding, heme binding, FMN binding, electron carrier activity, cAMP-dependent protein kinase regulator activity, tetrahydrobiopterin binding, arginine binding
Biological process: defense response to bacterium, superoxide metabolic process, inflammatory response, oxidation reduction, regulation of cell proliferation, nitric oxide biosynthetic process, response to hypoxia, ovulation from ovarian follicle, defense response to Gram-negative bacterium, retinoic acid receptor signaling pathway, regulation of blood pressure, regulation of heart contraction, protein kinase cascade, G-protein signaling, coupled to cGMP nucleotide second messenger, signal transduction, blood vessel remodeling, endothelial cell proliferation, arginine catabolic process
Cellular component: cytosol, perinuclear region of cytoplasm, cortical cytoskeleton, cytoplasm, peroxisome, nucleus

19.  1qw4B

LRMSD: 0.179253235459
p-value: 0.000139074865729
Matching residues: CYS194 VAL346 TRP366 TYR367 GLU371 ASP376
EC class: 1.14.13.39
GO terms:
Molecular function: protein binding, calmodulin binding, metal ion binding, oxidoreductase activity, zinc ion binding, iron ion binding, nitric-oxide synthase activity, protein homodimerization activity, NADP or NADPH binding, FAD binding, heme binding, FMN binding, electron carrier activity, cAMP-dependent protein kinase regulator activity, tetrahydrobiopterin binding, arginine binding
Biological process: defense response to bacterium, superoxide metabolic process, inflammatory response, oxidation reduction, regulation of cell proliferation, nitric oxide biosynthetic process, response to hypoxia, ovulation from ovarian follicle, defense response to Gram-negative bacterium, retinoic acid receptor signaling pathway, regulation of blood pressure, regulation of heart contraction, protein kinase cascade, G-protein signaling, coupled to cGMP nucleotide second messenger, signal transduction, blood vessel remodeling, endothelial cell proliferation, arginine catabolic process
Cellular component: cytosol, perinuclear region of cytoplasm, cortical cytoskeleton, cytoplasm, peroxisome, nucleus

20.  1zzsB

LRMSD: 0.179909601808
p-value: 0.000139108524309
Matching residues: CYS186 VAL338 TRP358 TYR359 GLU363 ASP368
EC class: 1.14.13.39
GO terms:
Molecular function: metal ion binding, oxidoreductase activity, zinc ion binding, calmodulin binding, calcium ion binding, iron ion binding, nitric-oxide synthase activity, NADP or NADPH binding, FAD binding, heme binding, FMN binding, electron carrier activity
Biological process: angiogenesis, ovulation from ovarian follicle, blood vessel remodeling, regulation of sodium ion transport, negative regulation of muscle hyperplasia, smooth muscle hyperplasia, lung development, lipopolysaccharide-mediated signaling pathway, negative regulation of potassium ion transport, positive regulation of angiogenesis, regulation of blood vessel size, negative regulation of hydrolase activity, negative regulation of calcium ion transport, oxidation reduction, blood coagulation, nitric oxide biosynthetic process, positive regulation of guanylate cyclase activity, anti-apoptosis, mitochondrion organization, arginine catabolic process
Cellular component: caveola, Golgi apparatus, membrane, plasma membrane, cytoskeleton, cytoplasm