The LabelHash Server

Top 150 matches

For each match you can click on the "[pdb]" link to download a PDB file with the matching chain aligned with the motif.
Download a zip file with PDB files for all the matches and the motif itself.

PDB ID		LRMSD / p-value	Matching Residues	EC	Gene Ontology annotations
PDB ID		LRMSD / p-value	Matching Residues	EC	Biological Process	Cellular Component	Molecular Function
1epzA dtdp-6-deoxy-d-xylo-4-hexulose 3,5-epimerase	[pdb]	0.131 2.04e-05	53^SER 61^ARG 64^HIS 73^LYS 90^ARG 172^ASP	0.0.0.0	lipopolysaccharide biosynthetic process extracellular polysaccharide biosynthetic process		dTDP-4-dehydrorhamnose 3,5-epimerase activity isomerase activity
1dztA dtdp-4-dehydrorhamnose 3,5-epimerase	[pdb]	0.313 6.42e-05	52^SER 60^ARG 63^HIS 73^LYS 90^ARG 170^ASP	5.1.3.13	lipopolysaccharide biosynthetic process		dTDP-4-dehydrorhamnose 3,5-epimerase activity isomerase activity
1rtvA dtdp-4-dehydrorhamnose 3,5-epimerase	[pdb]	0.426 9.91e-05	51^SER 59^ARG 62^HIS 71^LYS 88^ARG 168^ASP	0.0.0.0	lipopolysaccharide biosynthetic process		dTDP-4-dehydrorhamnose 3,5-epimerase activity isomerase activity
1upiA dtdp-4-dehydrorhamnose 3,5-epimerase	[pdb]	0.577 0.000163	51^SER 59^ARG 62^HIS 72^LYS 89^ARG 171^ASP	0.0.0.0	lipopolysaccharide biosynthetic process dTDP-rhamnose biosynthetic process growth extracellular polysaccharide biosynthetic process		dTDP-4-dehydrorhamnose 3,5-epimerase activity isomerase activity protein homodimerization activity
1nywA dtdp-6-deoxy-d-xylo-4-hexulose 3,5-epimerase	[pdb]	0.63 0.000202	65^SER 73^ARG 76^HIS 82^LYS 100^ARG 180^ASP	0.0.0.0	lipopolysaccharide biosynthetic process		dTDP-4-dehydrorhamnose 3,5-epimerase activity isomerase activity
2b9uG hypothetical dtdp-4-dehydrorhamnose 3,5-epimerase	[pdb]	0.644 0.000213	50^SER 58^ARG 61^HIS 71^LYS 88^ARG 163^ASP	0.0.0.0	lipopolysaccharide biosynthetic process		dTDP-4-dehydrorhamnose 3,5-epimerase activity
1oi6B pcza361.16	[pdb]	0.708 0.000257	52^SER 60^ARG 63^HIS 73^LYS 90^ARG 170^ASP	0.0.0.0	lipopolysaccharide biosynthetic process		dTDP-4-dehydrorhamnose 3,5-epimerase activity
2c0zA novw	[pdb]	0.746 0.000286	51^SER 59^ARG 62^HIS 72^LYS 89^ARG 168^ASP	0.0.0.0	lipopolysaccharide biosynthetic process		dTDP-4-dehydrorhamnose 3,5-epimerase activity
2glfB probable m18-family aminopeptidase 1	[pdb]	1.33 0.000422	32^ALA 256^ALA 94^HIS 73^LYS 293^ARG 328^ASP	0.0.0.0	proteolysis	vacuole	aminopeptidase activity peptidase activity metallopeptidase activity zinc ion binding hydrolase activity metal ion binding
1md9A 2,3-dihydroxybenzoate-amp ligase	[pdb]	1.33 0.000422	388^THR 202^ARG 204^HIS 212^LYS 34^ARG 183^ASP	0.0.0.0	metabolic process siderophore biosynthetic process	cytoplasm	nucleotide binding catalytic activity ATP binding (2,3-dihydroxybenzoyl)adenylate synthase activity ligase activity
1ti8A hemagglutinin	[pdb]	1.37 0.000483	219^ALA 229^ARG 183^HIS 193^LYS 131^GLU 231^ASP	0.0.0.0	viral envelope fusion with host membrane viral envelope fusion with host membrane	membrane integral to membrane virion viral envelope host cell plasma membrane host cell membrane membrane integral to membrane virion viral envelope host cell plasma membrane host cell membrane	host cell surface receptor binding host cell surface receptor binding
3hjeA 704aa long hypothetical glycosyltransferase	[pdb]	1.37 0.000495	55^THR 40^ALA 46^HIS 13^LYS 598^ARG 49^ASP	0.0.0.0	carbohydrate metabolic process		catalytic activity transferase activity cation binding
2dkcB phosphoacetylglucosamine mutase	[pdb]	1.39 0.000509	287^ALA 435^ALA 391^HIS 314^LYS 364^ARG 294^ASP	5.4.2.3	carbohydrate metabolic process		magnesium ion binding phosphoacetylglucosamine mutase activity isomerase activity intramolecular transferase activity phosphotransferases
2qyvB xaa-his dipeptidase	[pdb]	1.4 0.000536	111^THR 114^ALA 76^HIS 28^LYS 49^ARG 169^ASP	0.0.0.0	proteolysis metabolic process		protein binding hydrolase activity dipeptidase activity
1hrdB glutamate dehydrogenase	[pdb]	1.47 0.000728	227^THR 219^ALA 403^HIS 248^LYS 205^ARG 408^ASP	1.4.1.2	cellular amino acid metabolic process metabolic process oxidation-reduction process		catalytic activity glutamate dehydrogenase activity binding oxidoreductase activity oxidoreductase activity
1v5wB meiotic recombination protein dmc1/lim15 homolog	[pdb]	1.48 0.000754	329^ALA 332^ALA 137^HIS 132^LYS 192^ARG 172^ASP	0.0.0.0	pachytene ovarian follicle development oocyte maturation DNA metabolic process cell cycle meiosis reciprocal meiotic recombination male meiosis I gamete generation spermatogenesis spermatid development female gamete generation	condensed nuclear chromosome nucleus cytoplasm intracellular membrane-bounded organelle	nucleotide binding DNA binding protein binding ATP binding DNA-dependent ATPase activity nucleoside-triphosphatase activity
3krgA pectate lyase	[pdb]	1.48 0.00078	303^SER 206^ARG 221^HIS 218^LYS 110^ARG 161^ASP	4.2.2.2		extracellular region	lyase activity pectate lyase activity metal ion binding
3pt1A upf0364 protein ymr027w	[pdb]	1.49 0.000807	336^SER 328^ALA 303^HIS 296^LYS 135^ARG 325^ASP			nucleus cytoplasm
3n0lB serine hydroxymethyltransferase	[pdb]	1.51 0.000867	169^ALA 173^ALA 310^HIS 224^LYS 365^ARG 308^ASP	2.1.2.1	glycine metabolic process L-serine metabolic process one-carbon metabolic process	cytoplasm	catalytic activity glycine hydroxymethyltransferase activity protein binding transferase activity pyridoxal phosphate binding
3ou5A serine hydroxymethyltransferase, mitochondrial	[pdb]	1.52 0.000934	209^THR 213^ALA 364^HIS 264^LYS 418^ARG 362^ASP	2.1.2.1	glycine metabolic process L-serine metabolic process one-carbon metabolic process	mitochondrion mitochondrial matrix mitochondrial nucleoid	catalytic activity glycine hydroxymethyltransferase activity protein binding methyltransferase activity transferase activity pyridoxal phosphate binding
2j5tD glutamate 5-kinase	[pdb]	1.54 0.00101	224^ALA 367^ARG 325^HIS 266^LYS 329^ARG 322^ASP	2.7.2.11	proline biosynthetic process cellular amino acid biosynthetic process	cytoplasm	nucleotide binding magnesium ion binding RNA binding glutamate 5-kinase activity ATP binding kinase activity transferase activity
2z8yC carbon monoxide dehydrogenase/acetyl coasynthase subunit beta carbon monoxide dehydrogenase/acetyl coasynthase subunit alpha	[pdb]	1.54 0.00105	318^LEU 248^ILE 246^ARG 587^LEU 236^ALA 250^ALA	1.2.7.4, 1.2.99.2	generation of precursor metabolites and energy transport carbon fixation electron transport chain oxidation-reduction process acetyl-CoA metabolic process carbon fixation oxidation-reduction process	cytoplasm	catalytic activity nickel ion binding oxidoreductase activity carbon-monoxide dehydrogenase (acceptor) activity carbon-monoxide dehydrogenase (ferredoxin) activity metal ion binding iron-sulfur cluster binding 4 iron 4 sulfur cluster binding catalytic activity transferase activity carbon-monoxide dehydrogenase (acceptor) activity CO-methylating acetyl-CoA synthase activity metal ion binding iron-sulfur cluster binding
2x1lC methionyl-trna synthetase	[pdb]	1.55 0.00109	29^THR 291^ALA 270^HIS 287^LYS 174^ARG 265^ASP	0.0.0.0	translation tRNA aminoacylation for protein translation methionyl-tRNA aminoacylation	cytoplasm	nucleotide binding aminoacyl-tRNA ligase activity methionine-tRNA ligase activity ATP binding ligase activity
1y7pA hypothetical protein af1403	[pdb]	1.55 0.00109	168^SER 171^ARG 202^HIS 86^LYS 110^ARG 212^ASP	0.0.0.0	metabolic process		amino acid binding
3h2zA mannitol-1-phosphate 5-dehydrogenase	[pdb]	1.56 0.00114	336^SER 292^ARG 220^HIS 300^LYS 211^ARG 288^ASP	1.1.1.17	metabolic process oxidation-reduction process		catalytic activity binding mannitol-1-phosphate 5-dehydrogenase activity oxidoreductase activity coenzyme binding
1zwxA sphingomyelinase-c	[pdb]	1.56 0.00114	277^ALA 259^ALA 325^HIS 270^LYS 68^ARG 282^ASP	3.1.4.12	pathogenesis cytolysis hemolysis in other organism	extracellular region	sphingomyelin phosphodiesterase activity phosphoric diester hydrolase activity hydrolase activity
2hbvB 2-amino-3-carboxymuconate 6-semialdehydedecarboxylase	[pdb]	1.56 0.00118	119^ALA 129^ALA 166^HIS 223^LYS 217^ARG 127^ASP	0.0.0.0	metabolic process		catalytic activity
1ynfE succinylarginine dihydrolase	[pdb]	1.58 0.00128	111^ALA 177^ALA 248^HIS 135^LYS 208^ARG 250^ASP	3.5.3.23	arginine metabolic process arginine catabolic process response to stress		protein binding N-succinylarginine dihydrolase activity hydrolase activity
3owaB acyl-coa dehydrogenase	[pdb]	1.58 0.00128	219^SER 188^ALA 59^HIS 224^LYS 393^ARG 62^ASP	0.0.0.0	metabolic process oxidation-reduction process		acyl-CoA dehydrogenase activity oxidoreductase activity oxidoreductase activity acting on the CH-CH group of donors
3grkE enoyl-(acyl-carrier-protein) reductase (nadh)	[pdb]	1.58 0.00133	152^ALA 192^ALA 248^HIS 174^LYS 241^ARG 251^ASP	0.0.0.0	fatty acid biosynthetic process metabolic process oxidation-reduction process		catalytic activity enoyl-[acyl-carrier-protein] reductase (NADH) activity binding oxidoreductase activity
2wdeA sulfur oxidation protein soxb	[pdb]	1.59 0.00133	144^THR 52^ALA 55^HIS 321^LYS 107^ARG 430^ASP	0.0.0.0	nucleotide catabolic process		hydrolase activity
2vdcB glutamate synthase [nadph] large chain glutamate synthase [nadph] small chain	[pdb]	1.59 0.00139	322^ARG 315^SER 313^ALA 295^LEU 402^GLU 311^GLN	1.4.1.13	glutamate biosynthetic process glutamine metabolic process nitrogen compound metabolic process metabolic process cellular amino acid biosynthetic process oxidation-reduction process glutamate biosynthetic process metabolic process cellular amino acid biosynthetic process oxidation-reduction process		catalytic activity glutamate synthase (NADPH) activity glutamate synthase activity oxidoreductase activity metal ion binding iron-sulfur cluster binding 3 iron 4 sulfur cluster binding catalytic activity glutamate synthase (NADPH) activity binding oxidoreductase activity oxidoreductase activity acting on the CH-NH2 group of donors NAD or NADP as acceptor metal ion binding
2cfyE thioredoxin reductase 1	[pdb]	1.6 0.00144	198^ALA 206^ALA 243^HIS 235^LYS 416^ARG 215^ASP	1.8.1.9	mesoderm formation transport signal transduction gastrulation cell proliferation electron transport chain cell redox homeostasis oxidation-reduction process	nucleus cytoplasm mitochondrion cytosol	thioredoxin-disulfide reductase activity electron carrier activity protein disulfide oxidoreductase activity oxidoreductase activity oxidoreductase activity acting on a sulfur group of donors NAD or NADP as acceptor
3ce9C glycerol dehydrogenase	[pdb]	1.6 0.00144	239^ALA 245^ALA 250^HIS 322^LYS 313^ARG 171^ASP	0.0.0.0	aromatic amino acid family biosynthetic process oxidation-reduction process		3-dehydroquinate synthase activity oxidoreductase activity acting on CH-OH group of donors
3lmzA putative sugar isomerase	[pdb]	1.61 0.00157	177^THR 156^ALA 154^HIS 147^LYS 126^ARG 213^ASP	0.0.0.0
2hnhA dna polymerase iii alpha subunit	[pdb]	1.61 0.00157	38^ALA 10^ARG 12^HIS 52^LYS 506^ARG 201^ASP	2.7.7.7	DNA replication	cytoplasm	nucleic acid binding DNA binding catalytic activity DNA-directed DNA polymerase activity protein binding 3'-5' exonuclease activity transferase activity nucleotidyltransferase activity
3p0bA tt1467 protein	[pdb]	1.62 0.00157	308^ALA 314^ALA 300^HIS 292^LYS 86^ARG 317^ASP	0.0.0.0	carbohydrate metabolic process		catalytic activity
2wluA dps-like peroxide resistance protein	[pdb]	1.63 0.0017	98^SER 42^ALA 47^HIS 107^LYS 54^ARG 70^ASP	0.0.0.0	cellular iron ion homeostasis response to stress oxidation-reduction process cellular iron ion homeostasis response to stress oxidation-reduction process		DNA binding ferroxidase activity ferric iron binding oxidoreductase activity transition metal ion binding DNA binding ferroxidase activity ferric iron binding oxidoreductase activity transition metal ion binding
3m5fA metal dependent phosphohydrolase	[pdb]	1.63 0.0017	78^ALA 71^ALA 91^HIS 151^LYS 186^ARG 67^ASP	0.0.0.0
3p2lE atp-dependent clp protease proteolytic subunit	[pdb]	1.63 0.00177	161^THR 183^ALA 191^HIS 114^LYS 196^ARG 181^ASP	0.0.0.0	proteolysis	cytoplasm	nucleotide binding serine-type endopeptidase activity ATP binding peptidase activity serine-type peptidase activity hydrolase activity
1brwA protein (pyrimidine nucleoside phosphorylase)	[pdb]	1.65 0.00185	269^THR 293^ARG 278^HIS 81^LYS 230^ARG 290^ASP	2.4.2.2	pyrimidine base metabolic process pyrimidine nucleoside metabolic process metabolic process		pyrimidine-nucleoside phosphorylase activity transferase activity transferase activity transferring glycosyl groups transferase activity
2gjrA alpha-amylase	[pdb]	1.65 0.00185	114^THR 204^ALA 161^HIS 156^LYS 219^ARG 163^ASP	3.2.1.98	carbohydrate metabolic process metabolic process	extracellular region	catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds calcium ion binding hydrolase activity hydrolase activity acting on glycosyl bonds glucan 1,4-alpha-maltohexaosidase activity
2gl6G creatine kinase	[pdb]	1.65 0.00185	194^THR 204^ALA 253^HIS 209^LYS 220^ARG 202^ASP		creatine metabolic process muscle contraction	mitochondrion mitochondrial inner membrane membrane	nucleotide binding catalytic activity creatine kinase activity ATP binding kinase activity transferase activity transferase activity
1u4nA carboxylesterase est2	[pdb]	1.65 0.00192	291^SER 285^ALA 93^HIS 42^LYS 49^ARG 154^ASP	0.0.0.0
3oahA capsid protein vp1	[pdb]	1.66 0.00208	733^THR 730^ARG 422^HIS 689^LYS 311^ARG 611^ASP			viral capsid	structural molecule activity
2rgtB fusion of lim/homeobox protein lhx3, linker,insulin gene enhancer protein isl-1	[pdb]	1.67 0.00208	78^SER 49^ALA 53^HIS 57^LYS 44^ARG 51^ASP		neural crest cell migration heart morphogenesis regulation of transcription DNA-dependent multicellular organismal development heart development spinal cord motor neuron differentiation visceral motor neuron differentiation pituitary gland development neuron differentiation pancreas development axon regeneration retinal ganglion cell axon guidance positive regulation of insulin secretion negative regulation of neuron differentiation positive regulation of transcription from RNA polymerase II promoter neuron fate commitment mesenchymal cell differentiation regulation of transcription DNA-dependent motor axon guidance dorsal/ventral pattern formation medial motor column neuron differentiation pituitary gland development cell differentiation	intracellular nucleus intracellular part intracellular nucleus	DNA binding chromatin binding sequence-specific DNA binding transcription factor activity protein binding zinc ion binding transcription regulator activity sequence-specific DNA binding metal ion binding DNA binding sequence-specific DNA binding transcription factor activity protein binding zinc ion binding transcription regulator activity sequence-specific DNA binding metal ion binding
3hpaA amidohydrolase	[pdb]	1.67 0.00217	261^ALA 295^ALA 317^HIS 334^LYS 380^ARG 347^ASP	0.0.0.0
3dz1A dihydrodipicolinate synthase	[pdb]	1.67 0.00217	283^ALA 279^ARG 19^HIS 264^LYS 31^ARG 21^ASP	0.0.0.0	metabolic process		catalytic activity lyase activity
2x8cB thioredoxin glutathione reductase	[pdb]	1.68 0.00217	294^ALA 302^ALA 339^HIS 331^LYS 515^ARG 311^ASP	0.0.0.0	cell redox homeostasis oxidation-reduction process	cytoplasm	thioredoxin-disulfide reductase activity electron carrier activity protein disulfide oxidoreductase activity oxidoreductase activity oxidoreductase activity acting on a sulfur group of donors NAD or NADP as acceptor
1rt8A fimbrin	[pdb]	1.68 0.00225	323^ALA 336^ARG 358^HIS 350^LYS 231^ARG 334^ASP	0.0.0.0	cytokinesis actomyosin contractile ring assembly establishment or maintenance of cell polarity regulation of cell shape actin cytoskeleton organization ascospore formation negative regulation of actin filament depolymerization cell cycle cytokinesis actin filament bundle assembly actin cortical patch localization	cytoplasm actomyosin contractile ring cytoskeleton actin cortical patch actin filament bundle	actin binding calcium ion binding protein binding bridging
3eaoA thioredoxin reductase 1, cytoplasmic	[pdb]	1.68 0.00225	198^ALA 206^ALA 243^HIS 235^LYS 416^ARG 215^ASP	0.0.0.0	mesoderm formation response to oxidative stress gastrulation cell proliferation hydrogen peroxide catabolic process cell redox homeostasis oxidation-reduction process	nucleus cytoplasm mitochondrion cytosol	thioredoxin-disulfide reductase activity oxidoreductase activity oxidoreductase activity acting on a sulfur group of donors NAD or NADP as acceptor
3r1jA alpha-ketoglutarate-dependent taurine dioxygenase	[pdb]	1.68 0.00225	134^ALA 201^ALA 253^HIS 43^LYS 268^ARG 203^ASP
1hv8A putative atp-dependent rna helicase mj0669	[pdb]	1.68 0.00226	83^THR 300^ARG 324^HIS 57^LYS 331^ARG 296^ASP	0.0.0.0			nucleotide binding nucleic acid binding RNA binding helicase activity ATP binding ATP-dependent helicase activity hydrolase activity
1gpjA glutamyl-trna reductase	[pdb]	1.69 0.00235	208^ALA 197^ALA 224^HIS 168^LYS 257^ARG 219^ASP	1.2.1.70	porphyrin biosynthetic process metabolic process tetrapyrrole biosynthetic process oxidation-reduction process	cytoplasm	catalytic activity shikimate 5-dehydrogenase activity binding glutamyl-tRNA reductase activity oxidoreductase activity NADP binding
2ayiA aminopeptidase t	[pdb]	1.69 0.00235	289^ALA 347^ALA 345^HIS 213^LYS 405^ARG 378^ASP	0.0.0.0	proteolysis		aminopeptidase activity peptidase activity metallopeptidase activity hydrolase activity metal ion binding
1jmzA amine dehydrogenase	[pdb]	1.69 0.00244	307^ASP 197^VAL 189^ARG 261^LEU 85^SER 195^PRO	0.0.0.0	transport electron transport chain oxidation-reduction process	periplasmic space	oxidoreductase activity oxidoreductase activity acting on the CH-NH2 group of donors iron ion binding electron carrier activity
1j2bA trna(val) archaeosine trna-guanine transglycosylase	[pdb]	1.7 0.00254	375^SER 422^ALA 401^HIS 385^LYS 409^ARG 424^ASP	0.0.0.0	tRNA modification tRNA processing queuosine biosynthetic process		RNA binding zinc ion binding queuine tRNA-ribosyltransferase activity transferase activity transferase activity transferring glycosyl groups transferase activity
2qlzA transcription factor pf0095	[pdb]	1.7 0.00254	43^ALA 14^ARG 20^HIS 73^LYS 151^ARG 16^ASP	0.0.0.0	regulation of transcription	intracellular	sequence-specific DNA binding transcription factor activity
3cymA uncharacterized protein bad_0989	[pdb]	1.71 0.00264	38^SER 41^ALA 97^HIS 180^LYS 130^ARG 102^ASP	0.0.0.0	nucleobase nucleoside	intracellular	nucleotide binding nucleic acid binding catalytic activity 3'-5' exonuclease activity
2axcA colicin e7	[pdb]	1.72 0.00275	251^ALA 192^ALA 190^HIS 247^LYS 241^ARG 182^ASP	0.0.0.0	pathogenesis cytolysis defense response to bacterium	extrachromosomal circular DNA	nucleic acid binding nuclease activity endonuclease activity protein binding hydrolase activity metal ion binding
1ehyB protein (soluble epoxide hydrolase)	[pdb]	1.72 0.00286	167^SER 161^ALA 209^HIS 204^LYS 64^ARG 159^ASP	0.0.0.0	response to toxin	membrane	catalytic activity epoxide hydrolase activity hydrolase activity
3iofA beta-lactamase	[pdb]	1.72 0.00286	299^ALA 241^ALA 196^HIS 224^LYS 121^ARG 238^ASP	3.5.2.6	antibiotic catabolic process response to antibiotic	periplasmic space	zinc ion binding beta-lactamase activity hydrolase activity metal ion binding
1mvwD skeletal muscle myosin ii essential; light chain skeletal muscle myosin ii regulatory; lightchain skeletal muscle myosin ii rabbit skeletal muscle actin	[pdb]	1.72 0.00286	217^CYS 263^GLN 253^GLU 259^GLU 170^ALA 264^PRO	0.0.0.0	apoptosis actin filament-based movement skeletal muscle thin filament assembly actomyosin structure organization skeletal muscle fiber development cardiac myofibril assembly cardiac muscle tissue morphogenesis heart contraction	cytoplasm myosin complex myofibril myosin filament stress fiber cytoplasm cytoskeleton striated muscle thin filament actin filament sarcomere I band actomyosin actin part myosin complex	nucleotide binding motor activity actin binding calmodulin binding ATP binding nucleotide binding protein binding ATP binding ATPase activity myosin binding motor activity calcium ion binding motor activity calcium ion binding
1lp3A aav-2 capsid protein	[pdb]	1.73 0.00297	595^THR 592^ARG 284^HIS 551^LYS 173^ARG 473^ASP	0.0.0.0		virion viral capsid	structural molecule activity
3c9fB 5'-nucleotidase	[pdb]	1.73 0.00297	98^SER 81^ARG 115^HIS 124^LYS 188^ARG 34^ASP	0.0.0.0	nucleotide catabolic process		hydrolase activity
1bliA alpha-amylase	[pdb]	1.73 0.00297	112^THR 199^ALA 159^HIS 154^LYS 214^ARG 161^ASP	3.2.1.1	carbohydrate metabolic process metabolic process		catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds alpha-amylase activity calcium ion binding hydrolase activity hydrolase activity acting on glycosyl bonds
2dieA amylase	[pdb]	1.73 0.00297	114^THR 204^ALA 161^HIS 156^LYS 218^ARG 163^ASP	0.0.0.0	carbohydrate metabolic process		catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds calcium ion binding
3l7sA 5-methyltetrahydropteroyltriglutamate--homocysteinemethyltransferase	[pdb]	1.73 0.00297	548^THR 610^ALA 612^HIS 571^LYS 395^ARG 608^ASP	2.1.1.14	cellular amino acid biosynthetic process methionine biosynthetic process		5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity methyltransferase activity zinc ion binding transferase activity metal ion binding
2qa0A capsid protein	[pdb]	1.73 0.00297	735^THR 732^ARG 424^HIS 691^LYS 313^ARG 613^ASP	0.0.0.0		viral capsid	structural molecule activity
2okkA glutamate decarboxylase 2	[pdb]	1.73 0.00297	349^ALA 334^ALA 362^HIS 358^LYS 255^ARG 364^ASP	4.1.1.15	glutamate decarboxylation to succinate synaptic transmission carboxylic acid metabolic process neurotransmitter biosynthetic process	Golgi membrane cytoplasm Golgi apparatus cytosol plasma membrane membrane cytoplasmic membrane-bounded vesicle cell junction axon synaptic vesicle membrane anchored to membrane cytoplasmic vesicle presynaptic membrane synapse perinuclear region of cytoplasm	catalytic activity glutamate decarboxylase activity protein binding lyase activity carboxy-lyase activity pyridoxal phosphate binding
1jroD xanthine dehydrogenase, chain a xanthine dehydrogenase, chain b	[pdb]	1.73 0.00309	529^ALA 727^ALA 649^HIS 454^LYS 420^ARG 660^ASP	0.0.0.0	oxidation-reduction process oxidation-reduction process		catalytic activity xanthine dehydrogenase activity xanthine oxidase activity electron carrier activity oxidoreductase activity metal ion binding flavin adenine dinucleotide binding iron-sulfur cluster binding 2 iron 2 sulfur cluster binding xanthine dehydrogenase activity xanthine oxidase activity oxidoreductase activity molybdenum ion binding
1mezA adenylosuccinate synthetase	[pdb]	1.74 0.00309	209^THR 143^ALA 141^HIS 197^LYS 181^ARG 145^ASP	6.3.4.4	purine nucleotide metabolic process purine nucleotide biosynthetic process	cytoplasm membrane	nucleotide binding magnesium ion binding adenylosuccinate synthase activity protein binding GTP binding ligase activity metal ion binding
2pwgA sucrose isomerase	[pdb]	1.74 0.00309	143^SER 166^ARG 104^HIS 207^LYS 179^ARG 65^ASP	0.0.0.0	carbohydrate metabolic process		catalytic activity isomerase activity cation binding
2pgoB cyclohexane-1,2-dione hydrolase (cdh)	[pdb]	1.74 0.00309	288^ALA 281^ARG 300^HIS 297^LYS 196^ARG 304^ASP	0.0.0.0			magnesium ion binding catalytic activity hydrolase activity thiamine pyrophosphate binding metal ion binding
2g29A nitrate transport protein nrta	[pdb]	1.74 0.00309	413^SER 416^ARG 363^HIS 384^LYS 373^ARG 265^ASP	0.0.0.0	transport nitrate assimilation	plasma membrane membrane
3f93B beta-glucosidase	[pdb]	1.74 0.00321	248^SER 244^ALA 242^HIS 214^LYS 228^ARG 240^ASP	0.0.0.0	carbohydrate metabolic process		hydrolase activity
2apcA alpha-1,3-mannosyl-glycoprotein 2-beta-n-acetylglucosaminyltransferase	[pdb]	1.75 0.00321	423^THR 415^ARG 330^HIS 335^LYS 318^ARG 408^ASP	2.4.1.101	protein N-linked glycosylation	Golgi membrane Golgi apparatus membrane integral to membrane	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity transferase activity transferase activity
1gjqA nitrite reductase	[pdb]	1.75 0.00333	158^ALA 180^ALA 182^HIS 532^LYS 372^ARG 199^ASP	1.7.2.1, 1.7.99.1	transport electron transport chain oxidation-reduction process	periplasmic space	iron ion binding electron carrier activity oxidoreductase activity heme binding metal ion binding hydroxylamine reductase activity nitrite reductase (NO-forming) activity
3e0lB guanine deaminase	[pdb]	1.75 0.00333	273^THR 276^ALA 84^HIS 168^LYS 113^ARG 328^ASP	3.5.4.3	nucleobase nucleoside	intracellular	protein binding zinc ion binding guanine deaminase activity hydrolase activity metal ion binding
1m53A isomaltulose synthase	[pdb]	1.75 0.00333	184^SER 207^ARG 145^HIS 248^LYS 220^ARG 106^ASP	0.0.0.0	carbohydrate metabolic process		catalytic activity cation binding
2v7oA calcium/calmodulin-dependent protein kinase typeii gamma chain	[pdb]	1.75 0.00333	114^SER 263^ALA 126^HIS 154^LYS 66^ARG 264^ASP	2.7.11.17	protein phosphorylation insulin secretion	nucleoplasm cytosol plasma membrane calcium- and calmodulin-dependent protein kinase complex endocytic vesicle membrane	nucleotide binding protein kinase activity protein serine/threonine kinase activity calmodulin-dependent protein kinase activity calcium-dependent protein serine/threonine phosphatase activity calmodulin binding ATP binding kinase activity transferase activity
1n8sA triacylglycerol lipase, pancreatic colipase ii	[pdb]	1.76 0.00346	329^THR 265^ARG 263^HIS 238^LYS 256^ARG 176^ASP	3.1.1.3	digestion lipid catabolic process lipid metabolic process post-embryonic development lipid catabolic process intestinal cholesterol absorption response to lipid response to peptide hormone stimulus	extracellular region extracellular region extracellular space	enzyme activator activity catalytic activity triglyceride lipase activity lipase activity hydrolase activity
1v34A dna primase small subunit	[pdb]	1.77 0.00359	73^SER 153^ARG 142^HIS 306^LYS 317^ARG 140^ASP	0.0.0.0	DNA replication DNA replication	alpha DNA polymerase:primase complex	DNA primase activity DNA-directed RNA polymerase activity transferase activity nucleotidyltransferase activity metal ion binding
2pplA pancreatic lipase-related protein 1	[pdb]	1.78 0.00373	347^THR 283^ARG 281^HIS 256^LYS 274^ARG 194^ASP	3.1.1.3	lipid metabolic process post-embryonic development lipid catabolic process response to peptide hormone stimulus response to glucocorticoid stimulus	extracellular region extracellular space	catalytic activity triglyceride lipase activity calcium ion binding protein binding hydrolase activity lipase activity
3mdsA manganese superoxide dismutase	[pdb]	1.78 0.00373	43^ALA 74^ARG 80^HIS 5^LYS 88^ARG 152^ASP	1.15.1.1	superoxide metabolic process oxidation-reduction process		superoxide dismutase activity oxidoreductase activity metal ion binding
2faoB probable atp-dependent dna ligase	[pdb]	1.78 0.00388	544^ALA 636^ALA 573^HIS 566^LYS 776^ARG 578^ASP	0.0.0.0	DNA replication DNA replication synthesis of RNA primer DNA repair		DNA primase activity DNA ligase (ATP) activity ATP binding ligase activity
3gipA n-acyl-d-glutamate deacylase	[pdb]	1.78 0.00388	382^THR 376^ARG 248^HIS 352^LYS 259^ARG 365^ASP	0.0.0.0			zinc ion binding hydrolase activity hydrolase activity acting on carbon-nitrogen (but not peptide) bonds hydrolase activity
1zy9A alpha-galactosidase	[pdb]	1.78 0.00388	117^SER 177^ALA 418^HIS 166^LYS 484^ARG 380^ASP	0.0.0.0	carbohydrate metabolic process metabolic process		catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds alpha-galactosidase activity hydrolase activity hydrolase activity
2xzmK rps31e rps17e rps21e rps15e rps13e rps27e 18s rrna rps16e 40s ribosomal protein rps7e ribosomal protein s26e containing protein rps29e rps14e ribosomal protein s8 containing protein rps18e rps25e, ribosomal protein s4 containing protein rack1 ribosomal protein s10 containing protein ribosomal protein s7 containing protein 40s ribosomal protein s8 ribosomal protein s28e containing protein 40s ribosomal protein s4 ribosomal protein l7ae containing protein ribosomal protein s5 containing protein rps24e 40s ribosomal protein s12 kh domain containing protein eif1 rps30e ribosomal protein s17 containing protein rps19e plectin/s10 domain containing protein rps0e 40s ribosomal protein s3a rps6e	[pdb]	1.78 0.00388	114^VAL 78^MG 43^MG 96^GLN 50^MG 80^MG		translation translation translation translation translation translation translation translation translation translation translation translation translation translation translation translation translation	intracellular ribosome intracellular ribosome small ribosomal subunit ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome small ribosomal subunit intracellular ribosome ribonucleoprotein complex intracellular ribosome intracellular ribosome small ribosomal subunit intracellular ribosome intracellular ribosome intracellular ribosome small ribosomal subunit ribonucleoprotein complex intracellular ribosome small ribosomal subunit ribonucleoprotein complex intracellular ribosome intracellular ribosome intracellular cytoplasm ribosome ribonucleoprotein complex intracellular ribosome small ribosomal subunit ribonucleoprotein complex intracellular ribosome	structural constituent of ribosome structural constituent of ribosome RNA binding structural constituent of ribosome rRNA binding structural constituent of ribosome RNA binding structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome RNA binding structural constituent of ribosome RNA binding structural constituent of ribosome rRNA binding structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome RNA binding structural constituent of ribosome structural constituent of ribosome
1nouB beta-hexosaminidase beta chain	[pdb]	1.78 0.00388	516^SER 525^ALA 532^HIS 230^LYS 539^ARG 527^ASP	3.2.1.52	skeletal system development carbohydrate metabolic process N-acetylglucosamine metabolic process glycosphingolipid metabolic process ganglioside catabolic process cellular calcium ion homeostasis lysosome organization single fertilization penetration of zona pellucida sensory perception of sound locomotory behavior male courtship behavior metabolic process phospholipid biosynthetic process oligosaccharide catabolic process lipid storage sexual reproduction glycosaminoglycan metabolic process regulation of cellular metabolic process myelination cellular protein metabolic process oogenesis neuromuscular process controlling balance neuromuscular process	acrosomal vesicle soluble fraction lysosome membrane	catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds beta-N-acetylhexosaminidase activity sugar binding hexosaminidase activity beta-N-acetylglucosaminidase activity hydrolase activity hydrolase activity acting on glycosyl bonds protein homodimerization activity
2j9tA membrane antigen	[pdb]	1.79 0.00403	155^THR 148^ALA 95^HIS 53^LYS 41^ARG 145^ASP	0.0.0.0	pathogenesis	extracellular region
2oajA protein sni1	[pdb]	1.79 0.00403	894^ALA 499^ARG 526^HIS 73^LYS 520^ARG 528^ASP	0.0.0.0	exocytosis Golgi to plasma membrane transport small GTPase mediated signal transduction establishment of cell polarity	cytosol plasma membrane	SNARE binding Rab GTPase binding
1s6mA trwc dna (25-mer)	[pdb]	1.79 0.00403	201^ALA 109^ALA 161^HIS 92^LYS 156^ARG 111^ASP	0.0.0.0			helicase activity
2nlyA divergent polysaccharide deacetylasehypothetical protein	[pdb]	1.79 0.00403	70^THR 61^ALA 86^HIS 119^LYS 146^ARG 39^ASP	0.0.0.0	carbohydrate metabolic process		catalytic activity hydrolase activity
3gbeA sucrose isomerase smua from protaminobacterrubrum	[pdb]	1.79 0.00418	157^SER 179^ALA 118^HIS 221^LYS 193^ARG 79^ASP	0.0.0.0	carbohydrate metabolic process		catalytic activity cation binding isomaltulose synthase activity
3b9tB twin-arginine translocation pathway signalprotein	[pdb]	1.79 0.00418	447^ALA 430^ARG 470^HIS 474^LYS 319^ARG 427^ASP	0.0.0.0	metabolic process		hydrolase activity
1n6fF tricorn protease	[pdb]	1.8 0.00418	221^ALA 190^ARG 182^HIS 212^LYS 276^ARG 141^ASP	0.0.0.0	proteolysis	cytoplasm	protein binding peptidase activity serine-type peptidase activity hydrolase activity
3l4gN phenylalanyl-trna synthetase beta chain phenylalanyl-trna synthetase alpha chain	[pdb]	1.8 0.00418	434^THR 451^ARG 496^HIS 560^LYS 517^ARG 479^ASP	6.1.1.20	translation phenylalanyl-tRNA aminoacylation translation tRNA aminoacylation for protein translation phenylalanyl-tRNA aminoacylation	soluble fraction cytoplasm cytosol soluble fraction cytoplasm cytosol	nucleotide binding magnesium ion binding RNA binding aminoacyl-tRNA ligase activity phenylalanine-tRNA ligase activity ATP binding ligase activity tRNA binding nucleotide binding aminoacyl-tRNA ligase activity phenylalanine-tRNA ligase activity ATP binding ligase activity
4tmkA protein (thymidylate kinase)	[pdb]	1.8 0.00434	107^ALA 178^ALA 185^HIS 16^LYS 201^ARG 181^ASP	2.7.4.9	dTDP biosynthetic process dTTP biosynthetic process nucleotide biosynthetic process nucleobase	cytoplasm	nucleotide binding thymidylate kinase activity ATP binding kinase activity transferase activity
3pyuC 30s ribosomal protein s16 30s ribosomal protein s17 30s ribosomal protein s15 30s ribosomal protein s12 30s ribosomal protein s13 30s ribosomal protein s10 30s ribosomal protein s11 30s ribosomal protein thx 30s ribosomal protein s18 30s ribosomal protein s19 30s ribosomal protein s8 30s ribosomal protein s9 30s ribosomal protein s4 30s ribosomal protein s5 30s ribosomal protein s6 30s ribosomal protein s7 30s ribosomal protein s2 30s ribosomal protein s3 domain 3 of crpv igr ires rna 30s ribosomal protein s14 type z rna (34-mer) ribosomal rna 16s	[pdb]	1.8 0.00434	112^GLY 54^LYS 69^GLY 72^LEU 83^ARG 56^MET		translation translation translation translation translation translation translation translation translation translation translation translation translation translation translation translation translation translation translation	intracellular ribosome small ribosomal subunit ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex ribosome ribonucleoprotein complex intracellular ribosome small ribosomal subunit ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome small ribosomal subunit ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome small ribosomal subunit ribonucleoprotein complex intracellular ribosome small ribosomal subunit ribonucleoprotein complex intracellular ribosome small ribosomal subunit ribonucleoprotein complex intracellular ribosome small ribosomal subunit ribonucleoprotein complex ribosome ribonucleoprotein complex intracellular ribosome small ribosomal subunit ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex	tRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding rRNA binding RNA binding structural constituent of ribosome RNA binding structural constituent of ribosome rRNA binding tRNA binding nucleic acid binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding metal ion binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding metal ion binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding tRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding tRNA binding RNA binding structural constituent of ribosome rRNA binding
2eg7A dihydroorotase	[pdb]	1.81 0.00451	324^SER 271^ALA 18^HIS 26^LYS 59^ARG 250^ASP	3.5.2.3	pyrimidine nucleotide biosynthetic process pyrimidine base biosynthetic process		dihydroorotase activity hydrolase activity hydrolase activity acting on carbon-nitrogen (but not peptide) bonds
3kakB homoglutathione synthetase	[pdb]	1.81 0.00451	311^ALA 130^ARG 135^HIS 322^LYS 106^ARG 133^ASP	0.0.0.0	glutathione biosynthetic process		catalytic activity glutathione synthase activity ATP binding ligase activity
3lyeA oxaloacetate acetyl hydrolase	[pdb]	1.81 0.00451	176^SER 154^ALA 182^HIS 217^LYS 249^ARG 155^ASP	0.0.0.0
3a3yA na, k-atpase alpha subunit na+,k+-atpase beta subunit phospholemman-like protein	[pdb]	1.81 0.00451	635^SER 662^ALA 685^HIS 612^LYS 707^ARG 659^ASP	0.0.0.0	ATP biosynthetic process transport ion transport cation transport metabolic process monovalent inorganic cation transport ion transport ATP biosynthetic process transport ion transport potassium ion transport sodium ion transport	membrane integral to membrane membrane membrane integral to membrane	nucleotide binding catalytic activity ATP binding monovalent inorganic cation transmembrane transporter activity ATPase activity coupled to transmembrane movement of ions phosphorylative mechanism hydrolase activity hydrolase activity
1ckiB casein kinase i delta	[pdb]	1.81 0.00451	203^SER 198^ARG 123^HIS 159^LYS 165^ARG 270^ASP	2.7.11.1	mitotic cell cycle protein phosphorylation Wnt receptor signaling pathway positive regulation of proteasomal ubiquitin-dependent protein catabolic process circadian regulation of gene expression regulation of circadian rhythm	soluble fraction nucleus cytoplasm centrosome spindle	nucleotide binding glycoprotein binding protein kinase activity protein serine/threonine kinase activity protein binding ATP binding kinase activity transferase activity peptide binding phosphoprotein binding
2ghsA agr_c_1268p	[pdb]	1.81 0.00467	117^SER 94^ALA 153^HIS 158^LYS 199^ARG 126^ASP	0.0.0.0
1rp1A pancreatic lipase related protein 1	[pdb]	1.82 0.00468	329^THR 265^ARG 263^HIS 238^LYS 256^ARG 176^ASP	3.1.1.3	lipid metabolic process lipid catabolic process	extracellular region	catalytic activity triglyceride lipase activity calcium ion binding hydrolase activity lipase activity
1h4jA methanol dehydrogenase subunit 1 methanol dehydrogenase subunit 2	[pdb]	1.82 0.00485	462^THR 348^ALA 328^HIS 324^LYS 283^ARG 330^ASP	1.1.99.8	methanol metabolic process oxidation-reduction process methanol metabolic process methanol oxidation oxidation-reduction process	plasma membrane membrane outer membrane-bounded periplasmic space periplasmic space	calcium ion binding oxidoreductase activity oxidoreductase activity acting on CH-OH group of donors alcohol dehydrogenase (acceptor) activity metal ion binding alcohol dehydrogenase (NAD) activity oxidoreductase activity
3obiC formyltetrahydrofolate deformylase	[pdb]	1.82 0.00485	172^ALA 266^ALA 270^HIS 90^LYS 83^ARG 236^ASP	0.0.0.0	'de novo' IMP biosynthetic process metabolic process biosynthetic process		formyltetrahydrofolate deformylase activity amino acid binding hydroxymethyl- formyl- and related transferase activity
1f1gC copper-zinc superoxide dismutase	[pdb]	1.82 0.00485	348^SER 353^ARG 430^HIS 318^LYS 425^ARG 434^ASP	1.15.1.1	age-dependent response to reactive oxygen species involved in chronological cell aging superoxide metabolic process cellular copper ion homeostasis cellular zinc ion homeostasis fungal-type cell wall organization positive regulation of sequence-specific DNA binding transcription factor activity oxidation-reduction process	nucleus cytoplasm mitochondrion mitochondrial intermembrane space cytosol	superoxide dismutase activity antioxidant activity oxidoreductase activity metal ion binding
3i62A atp-dependent rna helicase mss116 5'-r(upupupupupupupupupu)-3'	[pdb]	1.82 0.00485	269^ALA 438^ARG 462^HIS 153^LYS 341^ARG 434^ASP	0.0.0.0	Group I intron splicing Group II intron splicing mRNA processing regulation of translation RNA splicing	mitochondrion mitochondrial matrix	nucleotide binding nucleic acid binding RNA binding ATP-dependent RNA helicase activity helicase activity protein binding ATP binding ATP-dependent helicase activity hydrolase activity RNA strand annealing activity
1uirA polyamine aminopropyltransferase	[pdb]	1.83 0.00485	183^ALA 239^ALA 75^HIS 79^LYS 260^ARG 244^ASP	2.5.1.16	polyamine biosynthetic process spermidine biosynthetic process		catalytic activity spermidine synthase activity transferase activity
2c3mB pyruvate-ferredoxin oxidoreductase	[pdb]	1.83 0.00503	565^THR 571^ALA 467^HIS 435^LYS 175^ARG 485^ASP	0.0.0.0	metabolic process oxidation-reduction process		catalytic activity iron ion binding electron carrier activity oxidoreductase activity oxidoreductase activity acting on the aldehyde or oxo group of donors thiamine pyrophosphate binding
2gttP rna (99-mer) nucleoprotein	[pdb]	1.83 0.00503	129^THR 52^ALA 137^HIS 180^LYS 225^ARG 48^ASP	0.0.0.0		virion viral nucleocapsid host cell cytoplasm ribonucleoprotein complex	nucleic acid binding RNA binding
3oh5D 23s ribosomal rna 50s ribosomal protein l9 50s ribosomal protein l14 50s ribosomal protein l3 50s ribosomal protein l2 50s ribosomal protein l6 50s ribosomal protein l5 50s ribosomal protein l4 50s ribosomal protein l19 50s ribosomal protein l18 50s ribosomal protein l17 50s ribosomal protein l30 50s ribosomal protein l33 50s ribosomal protein l32 50s ribosomal protein l35 50s ribosomal protein l34 50s ribosomal protein l31 50s ribosomal protein l16 50s ribosomal protein l15 5s ribosomal rna 50s ribosomal protein l13 50s ribosomal protein l28 50s ribosomal protein l29 50s ribosomal protein l22 50s ribosomal protein l23 50s ribosomal protein l20 50s ribosomal protein l21 50s ribosomal protein l27 50s ribosomal protein l24 50s ribosomal protein l25	[pdb]	1.83 0.00503	89^PHE 107^THR 143^GLY 154^ASP 134^PRO 109^ALA	0.0.0.0	translation translation translation translation translation translation translation translation translation translation translation	intracellular ribosome ribonucleoprotein complex intracellular ribosome large ribosomal subunit ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome large ribosomal subunit ribonucleoprotein complex intracellular ribosome large ribosomal subunit ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex	structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome RNA binding structural constituent of ribosome rRNA binding tRNA binding RNA binding structural constituent of ribosome rRNA binding structural constituent of ribosome RNA binding structural constituent of ribosome transferase activity rRNA binding structural constituent of ribosome structural constituent of ribosome RNA binding structural constituent of ribosome rRNA binding metal ion binding
2ch5A nagk protein	[pdb]	1.83 0.00503	275^SER 156^ALA 161^HIS 219^LYS 197^ARG 152^ASP	2.7.1.59	N-acetylglucosamine metabolic process N-acetylmannosamine metabolic process	soluble fraction	nucleotide binding protein binding ATP binding N-acylmannosamine kinase activity kinase activity transferase activity N-acetylglucosamine kinase activity
3kdpA na+/k+ atpase gamma subunit transcript variant a sodium/potassium-transporting atpase subunitbeta-1 sodium/potassium-transporting atpase subunitalpha-1	[pdb]	1.83 0.00503	628^SER 655^ALA 678^HIS 605^LYS 700^ARG 652^ASP	3.6.3.9	ion transport ATP biosynthetic process transport ion transport potassium ion transport sodium ion transport regulation of the force of heart contraction ATP biosynthetic process transport ion transport cation transport potassium ion transport sodium ion transport metabolic process regulation of blood pressure monovalent inorganic cation transport negative regulation of glucocorticoid biosynthetic process response to drug negative regulation of heart contraction positive regulation of heart contraction positive regulation of striated muscle contraction	membrane membrane integral to membrane microsome plasma membrane membrane integral to membrane basolateral plasma membrane sarcolemma melanosome	ion channel activity sodium:potassium-exchanging ATPase activity nucleotide binding catalytic activity 4-nitrophenylphosphatase activity sodium:potassium-exchanging ATPase activity protein binding ATP binding monovalent inorganic cation transmembrane transporter activity ATPase activity coupled to transmembrane movement of ions phosphorylative mechanism hydrolase activity
2wdaA putative secreted lyase	[pdb]	1.84 0.00522	441^THR 421^ALA 513^HIS 525^LYS 662^ARG 423^ASP	0.0.0.0	carbohydrate metabolic process	extracellular region	catalytic activity lyase activity carbon-oxygen lyase activity acting on polysaccharides
1p49A steryl-sulfatase	[pdb]	1.84 0.00522	66^THR 436^ARG 456^HIS 507^LYS 522^ARG 438^ASP	3.1.6.2	lipid metabolic process steroid catabolic process female pregnancy learning or memory metabolic process steroid metabolic process positive regulation of cell proliferation epidermis development response to pH response to organic cyclic compound response to peptide hormone stimulus skin development response to estrogen stimulus	integral to membrane of membrane fraction membrane fraction nuclear envelope lysosome endosome endoplasmic reticulum endoplasmic reticulum membrane microsome Golgi apparatus plasma membrane membrane integral to membrane	catalytic activity steryl-sulfatase activity sulfuric ester hydrolase activity hydrolase activity metal ion binding
3iw2A cytochrome p450 cyp125	[pdb]	1.84 0.00522	356^THR 308^ARG 366^HIS 75^LYS 84^ARG 304^ASP	0.0.0.0	growth of symbiont in host oxidation-reduction process		monooxygenase activity iron ion binding electron carrier activity oxidoreductase activity heme binding metal ion binding
3o3rA aldo-keto reductase family 1, member b7	[pdb]	1.84 0.00522	11^ALA 156^ALA 178^HIS 203^LYS 169^ARG 150^ASP	0.0.0.0	oxidation-reduction process	mitochondrion	aldehyde reductase activity aldo-keto reductase activity oxidoreductase activity
3cu9A intracellular arabinanase	[pdb]	1.84 0.00522	199^ALA 202^ALA 271^HIS 230^LYS 301^ARG 147^ASP	0.0.0.0	carbohydrate metabolic process		hydrolase activity
3hidA adenylosuccinate synthetase	[pdb]	1.85 0.00542	180^ALA 113^ALA 111^HIS 163^LYS 148^ARG 115^ASP	6.3.4.4	purine nucleotide biosynthetic process	cytoplasm	nucleotide binding magnesium ion binding adenylosuccinate synthase activity GTP binding ligase activity metal ion binding
2d3cE glutamine synthetase	[pdb]	1.85 0.00542	293^THR 333^ARG 249^HIS 237^LYS 218^ARG 331^ASP	6.3.1.2	glutamine biosynthetic process nitrogen compound metabolic process	cytoplasm	nucleotide binding catalytic activity glutamate-ammonia ligase activity ATP binding ligase activity
1qr0A 4'-phosphopantetheinyl transferase sfp	[pdb]	1.85 0.00563	152^SER 98^ALA 85^HIS 75^LYS 67^ARG 100^ASP	0.0.0.0	fatty acid biosynthetic process macromolecule biosynthetic process antibiotic biosynthetic process		magnesium ion binding holo-[acyl-carrier-protein] synthase activity transferase activity metal ion binding
2fnuB aminotransferase	[pdb]	1.85 0.00563	158^ALA 131^ALA 274^HIS 252^LYS 262^ARG 106^ASP	0.0.0.0			catalytic activity pyridoxal phosphate binding
3eafA abc transporter, substrate binding protein	[pdb]	1.85 0.00563	360^ALA 367^ALA 387^HIS 155^LYS 420^ARG 381^ASP	0.0.0.0
2d3lA glucan 1,4-alpha-maltohexaosidase	[pdb]	1.86 0.00563	114^THR 204^ALA 161^HIS 156^LYS 218^ARG 163^ASP	3.2.1.98	carbohydrate metabolic process metabolic process	extracellular region	catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds calcium ion binding hydrolase activity hydrolase activity acting on glycosyl bonds glucan 1,4-alpha-maltohexaosidase activity
1c9wA cho reductase	[pdb]	1.86 0.00585	10^ALA 155^ALA 177^HIS 202^LYS 168^ARG 149^ASP	1.1.1.21	oxidation-reduction process	cytoplasm	aldehyde reductase activity oxidoreductase activity
1c7gA tyrosine phenol-lyase	[pdb]	1.86 0.00585	309^ALA 409^ARG 343^HIS 320^LYS 330^ARG 50^ASP	4.1.99.2	cellular amino acid metabolic process aromatic amino acid family metabolic process	cytoplasm	catalytic activity lyase activity carbon-carbon lyase activity pyridoxal phosphate binding tyrosine phenol-lyase activity
2v40A adenylosuccinate synthetase isozyme 2	[pdb]	1.86 0.00608	208^THR 142^ALA 140^HIS 196^LYS 180^ARG 144^ASP	6.3.4.4	immune system process purine nucleotide biosynthetic process AMP biosynthetic process purine ribonucleoside monophosphate biosynthetic process	cellular_component cytoplasm	nucleotide binding magnesium ion binding adenylosuccinate synthase activity GTP binding ligase activity phosphate binding metal ion binding
1qpoB quinolinate acid phosphoribosyl transferase	[pdb]	1.87 0.00608	621^THR 777^ARG 613^HIS 650^LYS 517^ARG 780^ASP	2.4.2.19	metabolic process NAD biosynthetic process pyridine nucleotide biosynthetic process	plasma membrane	catalytic activity nicotinate-nucleotide diphosphorylase (carboxylating) activity transferase activity transferase activity
1db3A gdp-mannose 4,6-dehydratase	[pdb]	1.87 0.00608	326^ALA 251^ALA 228^HIS 234^LYS 190^ARG 225^ASP	4.2.1.47	metabolic process lipopolysaccharide biosynthetic process GDP-mannose metabolic process cellular metabolic process	intracellular	catalytic activity binding GDP-mannose 4,6-dehydratase activity lyase activity coenzyme binding
1h0gA argadin chitinase b	[pdb]	1.87 0.00608	269^ALA 228^ALA 226^HIS 362^LYS 357^ARG 215^ASP	3.2.1.14	polysaccharide catabolic process carbohydrate metabolic process chitin catabolic process metabolic process	extracellular region	catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds chitinase activity hydrolase activity hydrolase activity acting on glycosyl bonds
1ebuC homoserine dehydrogenase	[pdb]	1.87 0.00608	93^THR 113^ALA 142^HIS 118^LYS 229^ARG 351^ASP	1.1.1.3	cellular amino acid metabolic process methionine metabolic process threonine metabolic process metabolic process cellular amino acid biosynthetic process branched chain family amino acid biosynthetic process methionine biosynthetic process threonine biosynthetic process isoleucine biosynthetic process oxidation-reduction process	nucleus cytoplasm	catalytic activity homoserine dehydrogenase activity binding oxidoreductase activity NADP binding
3m8yC phosphopentomutase	[pdb]	1.87 0.00608	20^ALA 326^ALA 89^HIS 79^LYS 222^ARG 13^ASP	5.4.2.7	metabolic process nucleotide metabolic process cellular metabolic compound salvage	cytoplasm	magnesium ion binding catalytic activity phosphopentomutase activity isomerase activity metal ion binding
2w38A sialidase	[pdb]	1.87 0.00608	119^THR 93^ALA 131^HIS 156^LYS 208^ARG 79^ASP	0.0.0.0
2vmoA serine hydroxymethyltransferase	[pdb]	1.87 0.00608	170^ALA 176^ARG 311^HIS 226^LYS 366^ARG 309^ASP	0.0.0.0	glycine metabolic process L-serine metabolic process one-carbon metabolic process		catalytic activity glycine hydroxymethyltransferase activity transferase activity pyridoxal phosphate binding
3a2kB trna(ile)-lysidine synthase bacterial trna	[pdb]	1.87 0.00631	40^C 33^C 128^HIS 4^C 216^ARG 30^C	0.0.0.0	translation tRNA processing	cytoplasm	nucleotide binding ATP binding ligase activity ligase activity
2przD orotate phosphoribosyltransferase 1	[pdb]	1.87 0.00631	59^ALA 160^ALA 197^HIS 9^LYS 205^ARG 162^ASP	2.4.2.10	'de novo' pyrimidine base biosynthetic process pyrimidine nucleotide biosynthetic process nucleoside metabolic process pyrimidine ribonucleoside biosynthetic process	nucleus cytoplasm	orotate phosphoribosyltransferase activity protein binding transferase activity transferase activity
3k1uA beta-xylosidase, family 43 glycosyl hydrolase	[pdb]	1.87 0.00631	226^THR 199^ALA 260^HIS 248^LYS 279^ARG 135^ASP	0.0.0.0	carbohydrate metabolic process		hydrolase activity hydrolyzing O-glycosyl compounds
1kq3A glycerol dehydrogenase	[pdb]	1.88 0.00656	279^ALA 274^ALA 252^HIS 326^LYS 137^ARG 169^ASP	1.1.1.6	glycerol metabolic process oxidation-reduction process		glycerol dehydrogenase activity oxidoreductase activity oxidoreductase activity acting on CH-OH group of donors
1ct9A asparagine synthetase b	[pdb]	1.88 0.00656	317^THR 386^ALA 381^HIS 172^LYS 188^ARG 384^ASP	6.3.5.4	asparagine biosynthetic process glutamine metabolic process cellular amino acid biosynthetic process cellular amino acid catabolic process	cytoplasm	nucleotide binding asparagine synthase (glutamine-hydrolyzing) activity asparaginase activity ATP binding amino acid binding ligase activity
2np9C dpgc	[pdb]	1.88 0.00656	19^THR 52^ALA 50^HIS 27^LYS 38^ARG 51^ASP	0.0.0.0	metabolic process		catalytic activity
3aeyA threonine synthase	[pdb]	1.88 0.00656	201^ALA 210^ARG 180^HIS 256^LYS 305^ARG 177^ASP		cellular amino acid metabolic process metabolic process threonine biosynthetic process		catalytic activity threonine synthase activity pyridoxal phosphate binding
3pulB dihydrodipicolinate synthase	[pdb]	1.88 0.00656	229^ALA 191^ALA 240^HIS 235^LYS 282^ARG 187^ASP	0.0.0.0	metabolic process cellular amino acid biosynthetic process lysine biosynthetic process diaminopimelate biosynthetic process	cytoplasm	catalytic activity dihydrodipicolinate synthase activity lyase activity
1keeE carbamoyl-phosphate synthetase small chain carbamoyl-phosphate synthetase large chain	[pdb]	1.88 0.00656	503^ALA 514^ARG 523^HIS 397^LYS 528^ARG 518^ASP	6.3.5.5	'de novo' pyrimidine base biosynthetic process pyrimidine nucleotide biosynthetic process arginine biosynthetic process glutamine metabolic process nitrogen compound metabolic process cellular amino acid biosynthetic process biosynthetic process pyrimidine nucleotide biosynthetic process arginine biosynthetic process glutamine metabolic process nitrogen compound metabolic process cellular amino acid biosynthetic process biosynthetic process pyrimidine nucleotide biosynthetic process arginine biosynthetic process nitrogen compound metabolic process metabolic process cellular amino acid biosynthetic process pyrimidine base biosynthetic process	cytoplasm cytosol	nucleotide binding catalytic activity carbamoyl-phosphate synthase activity carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity protein binding ATP binding ligase activity nucleotide binding catalytic activity carbamoyl-phosphate synthase activity carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity ATP binding ligase activity nucleotide binding catalytic activity carbamoyl-phosphate synthase activity carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity protein binding ATP binding amino acid binding ligase activity metal ion binding
1gjwA maltodextrin glycosyltransferase	[pdb]	1.88 0.00656	382^ALA 136^ALA 192^HIS 185^LYS 4^ARG 135^ASP	0.0.0.0	carbohydrate metabolic process		catalytic activity transferase activity cation binding
1b9bA protein (triosephosphate isomerase)	[pdb]	1.88 0.00656	160^ALA 192^ARG 188^HIS 146^LYS 135^ARG 228^ASP	2.7.2.3, 5.3.1.1	gluconeogenesis glycolysis pentose-phosphate shunt fatty acid biosynthetic process metabolic process lipid biosynthetic process	cytoplasm	nucleotide binding catalytic activity phosphoglycerate kinase activity triose-phosphate isomerase activity ATP binding kinase activity transferase activity isomerase activity
2rauA putative esterase	[pdb]	1.88 0.00656	32^SER 101^ARG 103^HIS 110^LYS 210^ARG 99^ASP	0.0.0.0