The LabelHash Server

Top 150 matches

For each match you can click on the "[pdb]" link to download a PDB file with the matching chain aligned with the motif.
Download a zip file with PDB files for all the matches and the motif itself.

PDB ID		LRMSD / p-value	Matching Residues	EC	Gene Ontology annotations
PDB ID		LRMSD / p-value	Matching Residues	EC	Biological Process	Cellular Component	Molecular Function
1b76B protein (glycyl-trna synthetase)	[pdb]	0.225 1.68e-05	188^GLU 311^ARG 239^GLU 241^GLU 359^GLU 361^SER	6.1.1.14	translation tRNA aminoacylation for protein translation glycyl-tRNA aminoacylation	cytoplasm	nucleotide binding aminoacyl-tRNA ligase activity glycine-tRNA ligase activity ATP binding ligase activity protein dimerization activity
1atiB glycyl-trna synthetase	[pdb]	0.385 5.41e-05	188^GLU 311^ARG 239^GLU 241^GLU 359^GLU 361^SER	6.1.1.14	translation tRNA aminoacylation for protein translation glycyl-tRNA aminoacylation	cytoplasm	nucleotide binding aminoacyl-tRNA ligase activity glycine-tRNA ligase activity ATP binding ligase activity protein dimerization activity
2q5iA glycyl-trna synthetase	[pdb]	0.846 0.000114	245^GLU 410^ARG 296^GLU 298^GLU 522^GLU 524^SER	6.1.1.14	translation tRNA aminoacylation for protein translation glycyl-tRNA aminoacylation cell death diadenosine tetraphosphate biosynthetic process regulated secretory pathway	soluble fraction cytoplasm mitochondrion mitochondrial matrix cytosol stored secretory granule	nucleotide binding aminoacyl-tRNA ligase activity glycine-tRNA ligase activity protein binding ATP binding ligase activity protein dimerization activity
3d6jA putative haloacid dehalogenase-like hydrolase	[pdb]	0.865 0.000124	23^THR 50^LEU 76^GLU 72^GLU 74^SER 77^ALA	0.0.0.0	metabolic process		catalytic activity phosphoglycolate phosphatase activity hydrolase activity
2p62B hypothetical protein ph0156	[pdb]	0.891 0.000143	153^GLU 20^LEU 12^THR 14^GLU 15^SER 205^SER	0.0.0.0
3iaeB benzaldehyde lyase	[pdb]	1.02 0.000251	327^GLU 211^LEU 218^THR 214^GLU 216^SER 219^ALA	0.0.0.0			magnesium ion binding catalytic activity lyase activity thiamine pyrophosphate binding
2px8A genome polyprotein [contains(core protein); envelope protein m (matrix protein); major envelope protein e; non-structural protein 1 (ns1); non- structural protein 2a (ns2a); flavivirin protease ns2b regulatory subunit; flavivirin protease ns3 catalytic subunit; non-structural protein 4a (ns4a); non-structural protein 4b (ns4b); rna-directed rna polymerase (ec 2.7.7.48) (ns5)]	[pdb]	1.04 0.000292	10^GLU 184^LEU 155^GLU 158^GLU 157^GLU 153^SER	3.4.21.91, 2.7.7.48	transcription RNA-dependent viral reproduction RNA metabolic process viral infectious cycle viral genome replication evasion by virus of host immune response methylation	membrane integral to membrane virion viral nucleocapsid viral capsid viral envelope host cell membrane virion part	nucleotide binding nucleic acid binding RNA binding RNA helicase activity double-stranded RNA binding catalytic activity RNA-directed RNA polymerase activity serine-type endopeptidase activity helicase activity mRNA (guanine-N7-)-methyltransferase activity mRNA (nucleoside-2'-O-)-methyltransferase activity structural molecule activity ATP binding methyltransferase activity transferase activity nucleotidyltransferase activity hydrolase activity nucleoside-triphosphatase activity
2oy0B methyltransferase	[pdb]	1.05 0.000292	10^GLU 184^LEU 155^GLU 158^GLU 157^GLU 153^SER	3.4.21.91, 2.7.7.48	transcription RNA-dependent viral reproduction RNA metabolic process viral infectious cycle viral genome replication evasion by virus of host immune response methylation interspecies interaction between organisms transcription RNA-dependent viral reproduction RNA metabolic process viral infectious cycle	membrane integral to membrane virion viral nucleocapsid viral capsid viral envelope host cell membrane virion part membrane integral to membrane virion viral capsid viral envelope host cell membrane virion part	nucleotide binding nucleic acid binding RNA binding RNA helicase activity double-stranded RNA binding catalytic activity RNA-directed RNA polymerase activity serine-type endopeptidase activity helicase activity mRNA (guanine-N7-)-methyltransferase activity mRNA (nucleoside-2'-O-)-methyltransferase activity structural molecule activity ATP binding methyltransferase activity transferase activity nucleotidyltransferase activity hydrolase activity nucleoside-triphosphatase activity nucleotide binding nucleic acid binding RNA binding RNA helicase activity double-stranded RNA binding catalytic activity RNA-directed RNA polymerase activity serine-type endopeptidase activity helicase activity structural molecule activity ATP binding methyltransferase activity hydrolase activity
2ovwD endoglucanase i	[pdb]	1.05 0.000304	15^THR 122^LEU 397^THR 393^GLU 126^GLU 128^SER	3.2.1.4	polysaccharide catabolic process carbohydrate metabolic process metabolic process cellulose catabolic process		hydrolase activity hydrolyzing O-glycosyl compounds cellulase activity hydrolase activity
3p8zA non-structural protein 5	[pdb]	1.05 0.000317	11^GLU 182^LEU 155^THR 158^GLU 157^GLU 153^SER	0.0.0.0	transcription RNA-dependent viral reproduction RNA metabolic process viral infectious cycle viral genome replication	membrane integral to membrane virion viral capsid viral envelope host cell membrane virion part	nucleotide binding nucleic acid binding RNA binding RNA helicase activity double-stranded RNA binding catalytic activity RNA-directed RNA polymerase activity serine-type endopeptidase activity helicase activity structural molecule activity ATP binding methyltransferase activity hydrolase activity
2zwiB alpha-/beta-galactoside alpha-2,3-sialyltransferase	[pdb]	1.09 0.000376	193^GLU 161^ARG 168^GLU 166^GLU 164^GLU 222^SER	0.0.0.0			transferase activity transferase activity
1avhA annexin v	[pdb]	1.1 0.00043	72^GLU 42^LEU 33^THR 36^GLU 37^SER 27^ALA	0.0.0.0	anti-apoptosis signal transduction blood coagulation response to organic substance negative regulation of coagulation protein homooligomerization	intracellular cytoplasm	phospholipase inhibitor activity calcium ion binding protein binding phospholipid binding calcium-dependent phospholipid binding receptor tyrosine kinase binding eukaryotic cell surface binding
1ipkB beta-conglycinin, beta chain	[pdb]	1.16 0.000621	160^THR 173^LEU 165^GLU 167^GLU 168^GLU 164^SER	0.0.0.0		vacuole aleurone grain	nutrient reservoir activity
3eucA histidinol-phosphate aminotransferase 2	[pdb]	1.16 0.000621	284^GLU 357^LEU 349^THR 351^GLU 352^GLU 348^SER	2.6.1.9	histidine biosynthetic process cellular amino acid biosynthetic process biosynthetic process		catalytic activity histidinol-phosphate transaminase activity transaminase activity transferase activity transferase activity transferring nitrogenous groups
3dc8B dihydropyrimidinase	[pdb]	1.17 0.000651	448^GLU 77^ARG 111^THR 444^GLU 73^GLU 110^SER	0.0.0.0			hydrolase activity hydrolase activity
2zzeA alanyl-trna synthetase	[pdb]	1.17 0.000651	736^THR 627^LEU 655^GLU 660^GLU 657^GLU 654^SER	6.1.1.7	translation alanyl-tRNA aminoacylation tRNA aminoacylation	cytoplasm	tRNA binding nucleotide binding aminoacyl-tRNA editing activity nucleic acid binding RNA binding aminoacyl-tRNA ligase activity alanine-tRNA ligase activity ATP binding ligase activity ligase activity forming aminoacyl-tRNA and related compounds
1f6tB protein (nucleoside diphosphate kinase)	[pdb]	1.17 0.000651	9^GLU 13^LEU 128^GLU 133^GLU 124^SER 126^SER	2.7.4.6	GTP biosynthetic process dGDP phosphorylation dGTP biosynthetic process from dGDP UTP biosynthetic process CTP biosynthetic process translational elongation cytoskeleton organization G-protein coupled receptor protein signaling pathway nucleotide metabolic process nucleoside triphosphate biosynthetic process response to bacterium	cytoplasm ribosome cytoskeleton plasma membrane stored secretory granule phagocytic vesicle	nucleotide binding nucleoside diphosphate kinase activity ATP binding kinase activity transferase activity metal ion binding
3p40A neurofascin	[pdb]	1.17 0.000651	267^GLU 332^ARG 328^THR 313^GLU 330^SER 254^SER		cell adhesion axon guidance peripheral nervous system development myelination synapse organization	plasma membrane membrane integral to membrane axon node of Ranvier	protein binding
3dojA dehydrogenase-like protein	[pdb]	1.18 0.000683	60^THR 31^ARG 52^GLU 48^GLU 49^SER 51^ALA	0.0.0.0	pentose-phosphate shunt valine metabolic process response to oxidative stress metabolic process oxidation-reduction process	cytosol	catalytic activity 3-hydroxybutyrate dehydrogenase activity phosphogluconate dehydrogenase (decarboxylating) activity binding 3-hydroxyisobutyrate dehydrogenase activity oxidoreductase activity coenzyme binding
3gufB low molecular weight heat shock protein	[pdb]	1.18 0.000717	93^GLU 100^ARG 90^THR 87^GLU 86^SER 89^SER		response to stress
3nlcA uncharacterized protein vp0956	[pdb]	1.19 0.000717	151^GLU 133^ARG 127^GLU 158^GLU 131^GLU 230^SER	0.0.0.0			oxidoreductase activity
2qezC ethanolamine ammonia-lyase heavy chain	[pdb]	1.2 0.00079	126^THR 117^LEU 306^THR 120^GLU 119^SER 309^ALA		cellular amino acid metabolic process metabolic process		catalytic activity ethanolamine ammonia-lyase activity lyase activity
1zs6A nucleoside diphosphate kinase 3	[pdb]	1.21 0.000872	22^GLU 26^LEU 141^GLU 146^GLU 137^SER 139^SER	2.7.4.6	GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process apoptosis induction of apoptosis nucleotide metabolic process	mitochondrion	nucleotide binding nucleoside diphosphate kinase activity ATP binding kinase activity transferase activity metal ion binding
2y1hB putative deoxyribonuclease tatdn3	[pdb]	1.21 0.000872	240^GLU 210^LEU 251^GLU 255^GLU 252^GLU 249^SER	0.0.0.0		nucleus mitochondrion	nuclease activity hydrolase activity endodeoxyribonuclease activity
2flqA nitric oxide synthase	[pdb]	1.22 0.000916	128^GLU 103^LEU 95^THR 97^GLU 98^GLU 93^ALA	0.0.0.0	nitric oxide biosynthetic process oxidation-reduction process		nitric-oxide synthase activity
1he1B exoenzyme s ras-related c3 botulinum toxin substrate 1	[pdb]	1.22 0.000916	207^THR 148^GLU 125^THR 122^ASP 121^ASP 124^ASP	0.0.0.0	protein ADP-ribosylation apoptosis cellular component movement inflammatory response cell adhesion cell-matrix adhesion small GTPase mediated signal transduction induction of apoptosis by extracellular signals response to wounding anatomical structure morphogenesis regulation of hydrogen peroxide metabolic process positive regulation of lamellipodium assembly lamellipodium assembly actin filament polymerization ruffle organization positive regulation of Rho protein signal transduction negative regulation of receptor-mediated endocytosis localization within membrane regulation of respiratory burst endocytosis hyperosmotic response cytoskeleton organization cell adhesion small GTPase mediated signal transduction axon guidance dendrite development cell migration cerebral cortex radially oriented cell migration embryonic olfactory bulb interneuron precursor migration lamellipodium assembly regulation of cell migration positive regulation of actin filament polymerization positive regulation of phosphatidylinositol 3-kinase activity Wnt receptor signaling pathway planar cell polarity pathway dopaminergic neuron differentiation small GTPase mediated signal transduction endocytosis hyperosmotic response cytoskeleton organization cell adhesion small GTPase mediated signal transduction axon guidance dendrite development cell migration cerebral cortex radially oriented cell migration embryonic olfactory bulb interneuron precursor migration lamellipodium assembly regulation of cell migration positive regulation of actin filament polymerization substrate adhesion-dependent cell spreading positive regulation of phosphatidylinositol 3-kinase activity Wnt receptor signaling pathway	membrane intracellular cytosol plasma membrane membrane melanosome intracellular membrane fraction cytoplasm plasma membrane membrane cytoplasmic membrane-bounded vesicle extrinsic to plasma membrane lamellipodium melanosome cell projection intracellular plasma membrane membrane melanosome intracellular membrane fraction cytoplasm cytosol plasma membrane membrane cytoplasmic membrane-bounded vesicle extrinsic to plasma membrane lamellipodium melanosome cell projection	NAD(P)+-protein-arginine ADP-ribosyltransferase activity GTPase activator activity nucleotide binding GTPase activity protein binding GTP binding enzyme binding GTP-dependent protein binding thioesterase binding nucleotide binding GTPase activity GTP binding nucleotide binding GTP binding nucleotide binding GTPase activity protein binding GTP binding
3hmxA ustekinumab fab heavy chain ustekinumab fab light chain interleukin-12 subunit alpha interleukin-12 subunit beta	[pdb]	1.22 0.000962	131^ALA 107^ASP 152^PHE 166^THR 168^GLY 151^TYR	0.0.0.0	natural killer cell activation involved in immune response positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target cell cycle arrest cell surface receptor linked signaling pathway response to UV-B cell migration sensory perception of pain natural killer cell activation positive regulation of interferon-gamma production positive regulation of natural killer cell activation positive regulation of smooth muscle cell apoptosis regulation of cytokine biosynthetic process T-helper 1 type immune response T-helper cell differentiation interferon-gamma biosynthetic process positive regulation of T cell proliferation positive regulation of activated T cell proliferation defense response to protozoan negative regulation of growth of symbiont in host positive regulation of interferon-gamma biosynthetic process positive regulation of cell adhesion negative regulation of smooth muscle cell proliferation positive regulation of lymphocyte proliferation positive regulation of T cell mediated cytotoxicity positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target immune response cell cycle arrest response to virus response to UV-B cell migration response to lipopolysaccharide positive regulation of interferon-gamma production positive regulation of natural killer cell activation positive regulation of smooth muscle cell apoptosis positive regulation of T cell proliferation positive regulation of tyrosine phosphorylation of Stat4 protein defense response to protozoan positive regulation of cell adhesion positive regulation of natural killer cell mediated cytotoxicity negative regulation of smooth muscle cell proliferation positive regulation of lymphocyte proliferation defense response to Gram-positive bacterium	extracellular region extracellular space membrane interleukin-12 complex extracellular region extracellular space interleukin-12 complex	signal transducer activity cytokine receptor activity cytokine activity interleukin-12 receptor binding protein binding interleukin-12 alpha subunit binding protein homodimerization activity protein heterodimerization activity growth factor activity cytokine activity interleukin-12 receptor binding protein binding growth factor activity interleukin-12 beta subunit binding interleukin-27 binding protein heterodimerization activity
3bywA putative arabinofuranosyltransferase	[pdb]	1.23 0.00101	141^GLU 98^ARG 144^THR 116^GLU 113^SER 139^ALA	0.0.0.0	peptidoglycan biosynthetic process	integral to membrane	transferase activity transferase activity
3iasC nadh-quinone oxidoreductase subunit 15 nadh-quinone oxidoreductase subunit 5 nadh-quinone oxidoreductase subunit 4 nadh-quinone oxidoreductase subunit 6 nadh-quinone oxidoreductase subunit 1 nadh-quinone oxidoreductase subunit 3 nadh-quinone oxidoreductase subunit 2 nadh-quinone oxidoreductase subunit 9	[pdb]	1.25 0.00116	308^GLN 329^LYS 321^MET 323^ALA 324^VAL 320^SER	1.6.99.5	oxidation-reduction process transport oxidation-reduction process ATP synthesis coupled electron transport oxidation-reduction process oxidation-reduction process oxidation-reduction process oxidation-reduction process transport oxidation-reduction process oxidation-reduction process	plasma membrane membrane plasma membrane membrane plasma membrane membrane plasma membrane membrane plasma membrane membrane plasma membrane membrane plasma membrane membrane plasma membrane membrane	electron carrier activity oxidoreductase activity oxidoreductase activity acting on NADH or NADPH metal ion binding quinone binding NADH dehydrogenase (quinone) activity iron-sulfur cluster binding 4 iron 4 sulfur cluster binding oxidoreductase activity oxidoreductase activity acting on NADH or NADPH quinone binding NADH dehydrogenase (quinone) activity NAD binding binding NADH dehydrogenase (ubiquinone) activity electron carrier activity oxidoreductase activity oxidoreductase activity acting on NADH or NADPH molybdenum ion binding metal ion binding quinone binding NADH dehydrogenase (quinone) activity iron-sulfur cluster binding 2 iron 2 sulfur cluster binding 4 iron 4 sulfur cluster binding oxidoreductase activity metal ion binding quinone binding NADH dehydrogenase (quinone) activity NAD binding iron-sulfur cluster binding 2 iron 2 sulfur cluster binding NADH dehydrogenase (ubiquinone) activity oxidoreductase activity oxidoreductase activity acting on NADH or NADPH metal ion binding quinone binding NADH dehydrogenase (quinone) activity iron-sulfur cluster binding 4 iron 4 sulfur cluster binding oxidoreductase activity quinone binding NADH dehydrogenase (quinone) activity NADH dehydrogenase (ubiquinone) activity oxidoreductase activity oxidoreductase activity acting on NADH or NADPH quinone binding NADH dehydrogenase (quinone) activity
1m9kB endothelial nitric-oxide synthase	[pdb]	1.25 0.00116	162^THR 128^ARG 156^GLU 152^GLU 154^GLU 158^ALA	1.14.13.39	angiogenesis ovulation from ovarian follicle response to hypoxia blood vessel remodeling regulation of sodium ion transport regulation of systemic arterial blood pressure by endothelin arginine catabolic process nitric oxide biosynthetic process anti-apoptosis mitochondrion organization signal transduction aging regulation of blood pressure negative regulation of cell proliferation response to heat response to lead ion negative regulation of platelet activation response to organic cyclic compound negative regulation of muscle hyperplasia smooth muscle hyperplasia lung development positive regulation of guanylate cyclase activity lipopolysaccharide-mediated signaling pathway response to estradiol stimulus response to lipopolysaccharide response to cytokine stimulus response to fluid shear stress response to drug response to amino acid stimulus negative regulation of potassium ion transport response to peptide hormone stimulus endothelial cell migration response to ethanol positive regulation of angiogenesis positive regulation of vasodilation negative regulation of smooth muscle cell proliferation regulation of blood vessel size negative regulation of hydrolase activity negative regulation of calcium ion transport response to hyperoxia response to lipoprotein stimulus oxidation-reduction process	Golgi membrane soluble fraction nucleus nucleolus cytoplasm Golgi apparatus cytosol cytoskeleton plasma membrane caveola membrane apical part of cell	actin monomer binding nitric-oxide synthase activity iron ion binding protein binding calmodulin binding FMN binding oxidoreductase activity heme binding tetrahydrobiopterin binding arginine binding cadmium ion binding metal ion binding flavin adenine dinucleotide binding NADP binding
1wclA transcription elongation protein nusa	[pdb]	1.26 0.00122	358^THR 407^ARG 380^THR 382^GLU 383^GLU 379^SER	0.0.0.0	DNA repair transcription termination DNA-dependent response to stress regulation of transcription termination DNA-dependent transcription antitermination DNA repair transcription termination DNA-dependent regulation of transcription termination DNA-dependent transcription antitermination DNA repair transcription termination DNA-dependent regulation of transcription termination		nucleotide binding DNA binding sequence-specific DNA binding transcription factor activity RNA binding protein binding transcription regulator activity nucleotide binding DNA binding sequence-specific DNA binding transcription factor activity RNA binding protein binding transcription regulator activity nucleotide binding DNA binding sequence-specific DNA binding transcription factor activity RNA binding protein binding transcription regulator activity nucleotide binding DNA binding sequence-specific DNA binding transcription factor activity RNA binding protein binding transcription regulator activity
2a8pA u8 snorna-binding protein x29	[pdb]	1.26 0.00122	91^GLU 59^LEU 140^GLU 135^GLU 138^GLU 141^ALA	0.0.0.0		nucleus nucleoplasm nucleolus	RNA binding hydrolase activity metal ion binding
1jz1M beta-galactosidase	[pdb]	1.26 0.00128	41^GLU 322^LEU 326^GLU 314^GLU 324^GLU 35^SER	3.2.1.23	carbohydrate metabolic process lactose catabolic process metabolic process	beta-galactosidase complex	catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds beta-galactosidase activity protein binding hydrolase activity hydrolase activity acting on glycosyl bonds carbohydrate binding
3ct9B acetylornithine deacetylase	[pdb]	1.27 0.00135	76^THR 97^LEU 329^THR 331^GLU 332^GLU 327^SER	0.0.0.0	proteolysis metabolic process		protein binding metallopeptidase activity hydrolase activity
3pl2C sugar kinase, ribokinase family	[pdb]	1.27 0.00135	182^GLU 174^ARG 206^GLU 203^GLU 204^GLU 208^ALA				fructokinase activity kinase activity transferase activity
2uxpA hth-type transcriptional regulator ttgr	[pdb]	1.27 0.00135	142^THR 151^ARG 78^GLU 80^GLU 82^GLU 77^SER	0.0.0.0	regulation of transcription		DNA binding sequence-specific DNA binding transcription factor activity specific transcriptional repressor activity transcription regulator activity
3cinA myo-inositol-1-phosphate synthase-related protein	[pdb]	1.28 0.00142	155^GLU 93^ARG 158^THR 134^GLU 91^SER 159^ALA	0.0.0.0	inositol biosynthetic process metabolic process phospholipid biosynthetic process		catalytic activity inositol-3-phosphate synthase activity binding
2j7uA rna dependent rna polymerase	[pdb]	1.28 0.00142	399^THR 433^LEU 426^GLU 428^GLU 429^GLU 424^ALA	0.0.0.0	transcription RNA-dependent viral reproduction RNA metabolic process viral infectious cycle viral genome replication methylation transcription RNA-dependent viral reproduction RNA metabolic process viral infectious cycle viral genome replication evasion by virus of host immune response	membrane integral to membrane virion viral capsid viral envelope host cell membrane virion part membrane integral to membrane virion viral nucleocapsid viral capsid viral envelope host cell membrane virion part	nucleotide binding nucleic acid binding RNA binding RNA helicase activity double-stranded RNA binding catalytic activity RNA-directed RNA polymerase activity serine-type endopeptidase activity helicase activity structural molecule activity ATP binding methyltransferase activity hydrolase activity nucleotide binding nucleic acid binding RNA binding RNA helicase activity double-stranded RNA binding catalytic activity RNA-directed RNA polymerase activity serine-type endopeptidase activity helicase activity mRNA (guanine-N7-)-methyltransferase activity mRNA (nucleoside-2'-O-)-methyltransferase activity structural molecule activity ATP binding methyltransferase activity transferase activity nucleotidyltransferase activity hydrolase activity nucleoside-triphosphatase activity
1ecqA glucarate dehydratase	[pdb]	1.29 0.00149	244^GLU 234^LEU 214^GLU 218^GLU 216^GLU 212^ALA	4.2.1.40	metabolic process glucarate catabolic process metabolic process glucarate catabolic process D-glucarate catabolic process		magnesium ion binding catalytic activity glucarate dehydratase activity lyase activity metal ion binding magnesium ion binding catalytic activity glucarate dehydratase activity lyase activity metal ion binding
2xs6A phosphatidylinositol 3-kinase regulatory subunit beta	[pdb]	1.3 0.00165	210^GLU 255^LEU 193^GLU 189^GLU 191^SER 194^ALA		signal transduction negative regulation of anti-apoptosis	intracellular cytosol phosphatidylinositol 3-kinase complex	protein binding 1-phosphatidylinositol-3-kinase activity phosphatidylinositol 3-kinase regulator activity
2vu5A nucleoside diphosphate kinase	[pdb]	1.3 0.00165	2^GLU 6^LEU 121^GLU 126^GLU 117^SER 119^SER	2.7.4.6	GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process nucleotide metabolic process	cytoplasm	nucleotide binding nucleoside diphosphate kinase activity ATP binding kinase activity transferase activity metal ion binding
1aeiD annexin xii	[pdb]	1.3 0.00165	66^GLU 40^LEU 31^THR 33^GLU 35^SER 25^ALA	0.0.0.0			calcium ion binding calcium-dependent phospholipid binding
2z00A dihydroorotase	[pdb]	1.31 0.00174	241^GLU 208^ARG 236^THR 203^GLU 205^GLU 235^SER	0.0.0.0	pyrimidine nucleotide biosynthetic process		dihydroorotase activity hydrolase activity hydrolase activity acting on carbon-nitrogen (but not peptide) bonds hydrolase activity
3gbuC uncharacterized sugar kinase ph1459	[pdb]	1.32 0.00183	212^THR 199^LEU 215^THR 193^GLU 195^GLU 191^ALA	0.0.0.0	D-ribose metabolic process		ribokinase activity kinase activity transferase activity
1d1xB bovine endothelial nitric oxide synthase heme domain	[pdb]	1.32 0.00194	164^THR 130^ARG 158^GLU 154^GLU 156^GLU 160^ALA	1.14.13.39	angiogenesis ovulation from ovarian follicle blood vessel remodeling regulation of sodium ion transport regulation of systemic arterial blood pressure by endothelin arginine catabolic process nitric oxide biosynthetic process anti-apoptosis mitochondrion organization blood coagulation negative regulation of cell proliferation negative regulation of muscle hyperplasia smooth muscle hyperplasia lung development positive regulation of guanylate cyclase activity lipopolysaccharide-mediated signaling pathway response to fluid shear stress negative regulation of potassium ion transport endothelial cell migration positive regulation of angiogenesis regulation of blood vessel size negative regulation of hydrolase activity negative regulation of calcium ion transport oxidation-reduction process	cytoplasm Golgi apparatus cytoskeleton plasma membrane caveola membrane	actin monomer binding nitric-oxide synthase activity iron ion binding protein binding calmodulin binding FMN binding oxidoreductase activity heme binding tetrahydrobiopterin binding arginine binding metal ion binding flavin adenine dinucleotide binding NADP binding
1qr4A protein (tenascin)	[pdb]	1.32 0.00194	13^GLU 114^ARG 167^GLU 165^GLU 159^SER 90^SER	0.0.0.0	cell adhesion signal transduction neuromuscular junction development response to wounding mesenchymal-epithelial cell signaling involved in prostate gland development prostate gland epithelium morphogenesis	extracellular region proteinaceous extracellular matrix basement membrane	receptor binding syndecan binding
1v1sD 2-keto-3-deoxygluconate kinase	[pdb]	1.33 0.00204	58^GLU 113^LEU 86^THR 9^GLU 111^SER 108^SER	0.0.0.0	D-ribose metabolic process		ribokinase activity kinase activity transferase activity
2xmoB lmo2642 protein	[pdb]	1.33 0.00204	103^THR 118^LEU 109^THR 112^GLU 113^GLU 52^ALA				hydrolase activity
2nn6A 3'-5' exoribonuclease csl4 homolog polymyositis/scleroderma autoantigen 1 exosome complex exonuclease rrp4 exosome complex exonuclease rrp46 exosome complex exonuclease rrp41 exosome complex exonuclease rrp40 exosome complex exonuclease rrp43 exosome complex exonuclease rrp42 exosome component 6	[pdb]	1.33 0.00216	127^ILE 76^SER 72^THR 119^TYR 73^CYS 71^VAL	0.0.0.0	rRNA processing RNA processing immune response rRNA processing RNA processing rRNA processing RNA processing rRNA processing rRNA processing rRNA processing rRNA processing RNA processing histone mRNA catabolic process rRNA processing RNA processing biological_process rRNA processing RNA processing RNA catabolic process	nuclear exosome (RNase complex) exosome (RNase complex) nucleus nucleolus cytoplasm exosome (RNase complex) nucleus nucleolus cytoplasm exosome (RNase complex) nucleus nucleolus cytoplasm exosome (RNase complex) nucleus nucleolus nuclear exosome (RNase complex) cytoplasmic exosome (RNase complex) exosome (RNase complex) nucleus nucleolus cytoplasm exosome (RNase complex) nucleus nucleolus cytoplasm exosome (RNase complex) nucleus nucleolus cytoplasm exosome (RNase complex) cellular_component nucleus nucleolus cytoplasm exosome (RNase complex) nucleus nucleolus	3'-5'-exoribonuclease activity RNA binding nuclease activity exonuclease activity protein binding hydrolase activity 3'-5'-exoribonuclease activity RNA binding nuclease activity exonuclease activity protein binding hydrolase activity 3'-5'-exoribonuclease activity RNA binding nuclease activity exonuclease activity hydrolase activity RNA binding nuclease activity exonuclease activity protein binding hydrolase activity 3'-5'-exoribonuclease activity RNA binding nuclease activity exonuclease activity protein binding hydrolase activity 3'-5'-exoribonuclease activity RNA binding nuclease activity exonuclease activity protein binding 7S RNA binding hydrolase activity 3'-5'-exoribonuclease activity RNA binding nuclease activity exonuclease activity protein binding hydrolase activity 3'-5'-exoribonuclease activity molecular_function RNA binding nuclease activity exonuclease activity protein binding hydrolase activity identical protein binding 3'-5'-exoribonuclease activity RNA binding nuclease activity exonuclease activity protein binding hydrolase activity
1xxoA hypothetical protein rv1155	[pdb]	1.34 0.00216	133^THR 70^LEU 85^THR 83^GLU 68^SER 67^ALA	0.0.0.0			FMN binding pyridoxal phosphate binding protein homodimerization activity
3qz3A ferritin	[pdb]	1.34 0.00216	100^GLU 50^ARG 23^GLU 56^GLU 27^SER 26^SER		iron ion transport cellular iron ion homeostasis oxidation-reduction process		binding ferric iron binding oxidoreductase activity transition metal ion binding
1vq0A 33 kda chaperonin	[pdb]	1.34 0.00216	256^GLU 242^LEU 274^GLU 278^GLU 276^GLU 273^SER	0.0.0.0	protein folding	cytoplasm	unfolded protein binding
1clcA endoglucanase celd; ec	[pdb]	1.34 0.00228	221^GLU 374^LEU 410^THR 369^GLU 372^GLU 414^SER	3.2.1.4	polysaccharide catabolic process carbohydrate metabolic process metabolic process cellulose catabolic process polysaccharide catabolic process carbohydrate metabolic process metabolic process cellulose catabolic process		catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds cellulase activity hydrolase activity hydrolase activity acting on glycosyl bonds catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds
3aboC ethanolamine ammonia-lyase heavy chain ethanolamine ammonia-lyase light chain	[pdb]	1.34 0.00228	347^GLU 117^ALA 306^HOH 120^LEU 119^GLY 309^ALA	0.0.0.0	cellular amino acid metabolic process cellular amino acid metabolic process metabolic process		ethanolamine ammonia-lyase activity lyase activity cobalamin binding catalytic activity protein binding ethanolamine ammonia-lyase activity lyase activity
3h1tA type i site-specific restriction-modificationsystem, r (restriction) subunit	[pdb]	1.34 0.00228	442^THR 491^ARG 517^THR 496^GLU 494^GLU 515^ALA	0.0.0.0	DNA modification		nucleic acid binding DNA binding catalytic activity helicase activity endonuclease activity ATP binding hydrolase activity
3adyA dotd	[pdb]	1.34 0.00228	95^THR 41^LEU 130^GLU 126^GLU 127^SER 129^ALA	0.0.0.0
1p1dA glutamate receptor interacting protein	[pdb]	1.34 0.00228	87^GLU 97^LEU 90^THR 92^GLU 93^GLU 89^SER	0.0.0.0	nervous system development	cytoplasm endoplasmic reticulum endoplasmic reticulum membrane plasma membrane endomembrane system postsynaptic density membrane cell junction neuronal cell body synapse postsynaptic membrane	protein binding
2ceiA ferritin heavy chain	[pdb]	1.34 0.00228	107^GLU 56^LEU 27^GLU 62^GLU 31^SER 30^ALA	1.16.3.1	iron ion transport cellular iron ion homeostasis intracellular sequestering of iron ion post-Golgi vesicle-mediated transport immune response cell proliferation negative regulation of cell proliferation cellular membrane organization oxidation-reduction process	cytosol intracellular ferritin complex	ferroxidase activity binding iron ion binding protein binding ferric iron binding oxidoreductase activity metal ion binding transition metal ion binding
1drkA d-ribose-binding protein	[pdb]	1.35 0.0024	87^THR 37^LEU 66^THR 46^GLU 39^SER 9^SER	0.0.0.0	transport chemotaxis carbohydrate transport	membrane periplasmic space
2dx0A phospholipase c, gamma 2	[pdb]	1.35 0.0024	544^GLU 587^ARG 538^GLU 565^GLU 566^SER 539^SER	3.1.4.11	follicular B cell differentiation lipid metabolic process signal transduction elevation of cytosolic calcium ion concentration phospholipid catabolic process regulation of gene expression lipid catabolic process response to magnesium ion activation of store-operated calcium channel activity response to lipopolysaccharide inositol trisphosphate biosynthetic process response to ATP negative regulation of programmed cell death T cell receptor signaling pathway	membrane fraction	phosphatidylinositol phospholipase C activity phospholipase C activity signal transducer activity protein binding phosphoric diester hydrolase activity hydrolase activity
2hypA hypothetical protein rv0805	[pdb]	1.35 0.0024	198^THR 149^LEU 158^THR 155^GLU 154^GLU 157^ALA	0.0.0.0	pathogenesis		3',5'-cyclic-AMP phosphodiesterase activity iron ion binding ferric iron binding hydrolase activity manganese ion binding phosphate binding protein homodimerization activity
2y44A glutamic acid/alanine-rich protein	[pdb]	1.35 0.0024	168^GLU 203^LEU 59^THR 58^GLU 61^SER 63^SER
3mj5A replicase polyprotein 1a	[pdb]	1.35 0.0024	204^GLU 124^LEU 239^GLU 308^GLU 241^SER 182^ALA	0.0.0.0	proteolysis viral genome replication viral protein processing evasion by virus of host immune response interspecies interaction between organisms	membrane integral to membrane viral replication complex host cell cytoplasm host cell membrane host cell perinuclear region of cytoplasm perinuclear region of cytoplasm	RNA binding catalytic activity RNA-directed RNA polymerase activity peptidase activity cysteine-type peptidase activity zinc ion binding hydrolase activity metal ion binding
3fhhA outer membrane heme receptor shua	[pdb]	1.35 0.0024	9^THR 104^ARG 5^THR 101^GLU 23^SER 15^SER	0.0.0.0	transport	plasma membrane cell outer membrane membrane outer membrane	receptor activity transporter activity
1vpkA dna polymerase iii, beta subunit	[pdb]	1.35 0.00253	126^THR 192^LEU 188^GLU 160^GLU 190^SER 189^ALA	0.0.0.0	DNA replication	cytoplasm	DNA binding DNA-directed DNA polymerase activity 3'-5' exonuclease activity transferase activity nucleotidyltransferase activity
3dulA o-methyltransferase, putative	[pdb]	1.36 0.00253	88^THR 37^LEU 116^THR 93^GLU 92^SER 91^ALA	0.0.0.0			methyltransferase activity O-methyltransferase activity transferase activity
3lubH putative creatinine amidohydrolase	[pdb]	1.37 0.00281	156^GLU 230^ARG 165^GLU 167^GLU 169^SER 223^ALA	0.0.0.0
1mzhB deoxyribose-phosphate aldolase	[pdb]	1.37 0.00281	1175^GLU 1213^ARG 1169^THR 1207^GLU 1210^GLU 1170^SER	4.1.2.4	metabolic process deoxyribonucleotide catabolic process	cytoplasm	catalytic activity deoxyribose-phosphate aldolase activity lyase activity
1tr5A thermonuclease	[pdb]	1.37 0.00281	13^THR 36^LEU 73^GLU 75^GLU 92^GLU 94^ALA	3.1.31.1		extracellular region membrane	nucleic acid binding nuclease activity endonuclease activity hydrolase activity hydrolase activity acting on ester bonds
1rtrA geranyltranstransferase	[pdb]	1.37 0.00281	278^THR 182^LEU 268^GLU 204^GLU 207^SER 265^ALA	0.0.0.0	isoprenoid biosynthetic process		transferase activity
1wa3B 2-keto-3-deoxy-6-phosphogluconate aldolase	[pdb]	1.37 0.00281	50^THR 16^LEU 22^GLU 26^GLU 23^GLU 20^SER	0.0.0.0	metabolic process		catalytic activity
1v93A 5,10-methylenetetrahydrofolate reductase	[pdb]	1.37 0.00281	18^GLU 42^ARG 34^THR 36^GLU 37^GLU 277^SER	0.0.0.0	methionine metabolic process oxidation-reduction process		methylenetetrahydrofolate reductase (NADPH) activity oxidoreductase activity
2opwA phyhd1 protein	[pdb]	1.37 0.00281	88^GLU 62^ARG 55^THR 57^GLU 58^GLU 54^SER		oxidation-reduction process		oxidoreductase activity oxidoreductase activity acting on single donors with incorporation of molecular oxygen
3owaB acyl-coa dehydrogenase	[pdb]	1.37 0.00297	54^GLU 396^ARG 388^GLU 390^GLU 392^GLU 387^ALA	0.0.0.0	metabolic process oxidation-reduction process		acyl-CoA dehydrogenase activity oxidoreductase activity oxidoreductase activity acting on the CH-CH group of donors
2htmA putative thiamine biosynthesis protein this thiazole biosynthesis protein thig	[pdb]	1.37 0.00297	98^GLU 84^HOH 75^HOH 77^HOH 78^HOH 73^HOH	0.0.0.0	sulfur compound metabolic process metabolic process thiamine biosynthetic process	cytoplasm	catalytic activity lyase activity
2e8gA hypothetical protein ph0536	[pdb]	1.38 0.00297	23^THR 92^LEU 105^GLU 101^GLU 104^GLU 108^ALA	0.0.0.0			tRNA binding
2hmtA yuaa protein	[pdb]	1.38 0.00297	89^THR 64^LEU 58^THR 60^GLU 62^GLU 57^ALA	0.0.0.0	transport ion transport potassium ion transport metabolic process	plasma membrane membrane	catalytic activity binding cation transmembrane transporter activity
3djaA protein ct_858	[pdb]	1.38 0.00297	521^THR 180^ARG 171^THR 174^GLU 175^GLU 172^ALA	0.0.0.0	proteolysis		serine-type peptidase activity
2z6mK ferritin heavy chain	[pdb]	1.38 0.00297	107^GLU 56^LEU 27^GLU 62^GLU 31^SER 30^ALA	1.16.3.1	iron ion transport cellular iron ion homeostasis intracellular sequestering of iron ion post-Golgi vesicle-mediated transport immune response cell proliferation negative regulation of cell proliferation cellular membrane organization oxidation-reduction process	cytosol intracellular ferritin complex	ferroxidase activity binding iron ion binding protein binding ferric iron binding oxidoreductase activity metal ion binding transition metal ion binding
3l39A putative phou-like phosphate regulatory protein	[pdb]	1.38 0.00297	39^GLU 193^LEU 115^GLU 119^GLU 116^SER 114^SER	0.0.0.0
1moeB anti-cea mab t84.66	[pdb]	1.38 0.00313	206^THR 139^LEU 237^THR 129^GLU 235^SER 211^ALA	0.0.0.0			antigen binding
2j6eB igm ig gamma-1 chain c region	[pdb]	1.38 0.00313	393^THR 441^LEU 380^GLU 382^GLU 424^SER 426^SER	0.0.0.0	immune response	extracellular region membrane fraction	antigen binding protein binding
3o8nA 6-phosphofructokinase, muscle type	[pdb]	1.38 0.00313	111^THR 139^LEU 151^THR 148^GLU 149^GLU 153^SER		glycolysis	cytoplasm 6-phosphofructokinase complex	nucleotide binding 6-phosphofructokinase activity ATP binding protein C-terminus binding kinase activity transferase activity metal ion binding
3lofE heat shock 70 kda protein 1	[pdb]	1.38 0.00313	543^GLU 586^LEU 593^GLU 591^GLU 588^GLU 538^ALA	0.0.0.0	mRNA catabolic process anti-apoptosis response to stress response to unfolded protein negative regulation of cell proliferation negative regulation of cell growth protein refolding negative regulation of inclusion body assembly	nucleus cytoplasm mitochondrion endoplasmic reticulum inclusion body nuclear speck ribonucleoprotein complex perinuclear region of cytoplasm	nucleotide binding protein binding ATP binding ubiquitin protein ligase binding protein binding involved in protein folding protein N-terminus binding unfolded protein binding
1keeE carbamoyl-phosphate synthetase small chain carbamoyl-phosphate synthetase large chain	[pdb]	1.38 0.00313	255^ILE 265^VAL 235^GLY 217^THR 233^PRO 253^THR	6.3.5.5	'de novo' pyrimidine base biosynthetic process pyrimidine nucleotide biosynthetic process arginine biosynthetic process glutamine metabolic process nitrogen compound metabolic process cellular amino acid biosynthetic process biosynthetic process pyrimidine nucleotide biosynthetic process arginine biosynthetic process glutamine metabolic process nitrogen compound metabolic process cellular amino acid biosynthetic process biosynthetic process pyrimidine nucleotide biosynthetic process arginine biosynthetic process nitrogen compound metabolic process metabolic process cellular amino acid biosynthetic process pyrimidine base biosynthetic process	cytoplasm cytosol	nucleotide binding catalytic activity carbamoyl-phosphate synthase activity carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity protein binding ATP binding ligase activity nucleotide binding catalytic activity carbamoyl-phosphate synthase activity carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity ATP binding ligase activity nucleotide binding catalytic activity carbamoyl-phosphate synthase activity carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity protein binding ATP binding amino acid binding ligase activity metal ion binding
2yv5A yjeq protein	[pdb]	1.39 0.00313	223^THR 185^LEU 189^GLU 188^GLU 183^SER 179^SER	0.0.0.0			nucleotide binding GTPase activity GTP binding hydrolase activity metal ion binding nucleotide binding GTPase activity GTP binding hydrolase activity metal ion binding
1c0pA d-amino acid oxidase	[pdb]	1.39 0.00313	1346^GLU 1066^ARG 1074^THR 1072^GLU 1071^GLU 1341^SER	1.4.3.3	metabolic process oxidation-reduction process	peroxisome	catalytic activity D-amino-acid oxidase activity binding oxidoreductase activity
3buuB uncharacterized lola superfamily protein ne2245	[pdb]	1.39 0.0033	126^THR 199^LEU 62^THR 229^GLU 222^GLU 231^SER	0.0.0.0
3njeB general secretion pathway protein j	[pdb]	1.39 0.0033	159^THR 71^ARG 166^GLU 165^GLU 169^GLU 170^SER		transport protein secretion by the type II secretion system	type II protein secretion system complex	protein transporter activity
1htaA histone hmfa	[pdb]	1.39 0.00349	61^GLU 32^LEU 42^GLU 38^GLU 37^GLU 40^ALA	0.0.0.0		intracellular	DNA binding sequence-specific DNA binding
1mirA procathepsin b	[pdb]	1.39 0.00349	171^GLU 54^VAL 243^GLU 159^GLU 154^SER 244^SER	3.4.22.1	proteolysis autophagy response to stress skeletal muscle tissue development response to wounding response to mechanical stimulus response to glucose stimulus response to organic cyclic compound response to amine stimulus response to peptide hormone stimulus response to ethanol regulation of catalytic activity response to protein stimulus negative regulation of cell death response to interleukin-4	extracellular region extracellular space soluble fraction cytoplasm mitochondrion lysosome external side of plasma membrane cell surface apical plasma membrane sarcolemma melanosome caveola perinuclear region of cytoplasm	endopeptidase activity cysteine-type endopeptidase activity protein binding peptidase activity cysteine-type peptidase activity hydrolase activity kininogen binding protein complex binding peptide binding
1z3iX similar to rad54-like	[pdb]	1.4 0.00349	663^GLU 658^LEU 618^THR 622^GLU 623^GLU 667^SER	0.0.0.0			nucleic acid binding DNA binding helicase activity ATP binding DNA-dependent ATPase activity
1o8rA guanylin	[pdb]	1.4 0.00368	13^GLU 70^LEU 78^GLU 75^GLU 74^GLU 36^ALA	0.0.0.0	signal transduction	extracellular region	hormone activity enzyme activator activity guanylate cyclase activator activity
3a7cA toll-like receptor 2, variable lymphocytereceptor b	[pdb]	1.4 0.00368	288^THR 269^LEU 262^THR 264^GLU 265^SER 235^ALA	0.0.0.0	response to hypoxia toll-like receptor signaling pathway response to molecule of fungal origin microglial cell activation involved in immune response positive regulation of leukocyte migration cell surface pattern recognition receptor signaling pathway MyD88-dependent toll-like receptor signaling pathway inflammatory response immune response signal transduction I-kappaB phosphorylation response to bacterium response to toxin positive regulation of gene-specific transcription from RNA polymerase II promoter response to bacterial lipoprotein response to peptidoglycan response to lipopolysaccharide response to progesterone stimulus negative regulation of interleukin-12 production negative regulation of interleukin-17 production positive regulation of chemokine production positive regulation of interferon-beta production positive regulation of interleukin-12 production positive regulation of interleukin-18 production positive regulation of interleukin-6 production positive regulation of interleukin-8 production positive regulation of tumor necrosis factor production response to insulin stimulus positive regulation of toll-like receptor signaling pathway positive regulation of NF-kappaB import into nucleus detection of triacyl bacterial lipopeptide detection of diacyl bacterial lipopeptide positive regulation of tumor necrosis factor biosynthetic process defense response to bacterium chloramphenicol transport negative regulation of growth of symbiont in host innate immune response positive regulation of nitric oxide biosynthetic process defense response to Gram-positive bacterium positive regulation of NF-kappaB transcription factor activity positive regulation of nitric-oxide synthase biosynthetic process pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity induction by symbiont of defense-related host nitric oxide production positive regulation of macrophage cytokine production response to fatty acid cellular response to bacterial lipopeptide cellular response to lipoteichoic acid cellular response to peptidoglycan cellular response to diacyl bacterial lipopeptide cellular response to triacyl bacterial lipopeptide	cytoplasm plasma membrane external side of plasma membrane cell surface membrane integral to membrane phagocytic vesicle membrane intrinsic to membrane cytoplasmic vesicle Toll-like receptor 1-Toll-like receptor 2 protein complex Toll-like receptor 2-Toll-like receptor 6 protein complex	receptor activity protein binding receptor activity transmembrane receptor activity protein binding lipoprotein binding pattern recognition receptor activity triacyl lipopeptide binding diacyl lipopeptide binding peptidoglycan binding protein heterodimerization activity Gram-positive bacterial cell surface binding lipoteichoic acid binding
3bksA sterol carrier protein-2 like-3	[pdb]	1.41 0.00368	63^THR 46^LEU 57^GLU 55^GLU 43^SER 59^ALA	0.0.0.0			sterol binding
3gwbB peptidase m16 inactive domain family protein	[pdb]	1.41 0.00368	421^THR 252^LEU 321^GLU 324^GLU 323^SER 320^ALA	0.0.0.0	proteolysis		catalytic activity metalloendopeptidase activity zinc ion binding metal ion binding
1tygC thiazole biosynthesis protein thig yjbs	[pdb]	1.41 0.00368	215^THR 186^ARG 177^THR 179^GLU 180^GLU 175^ALA	0.0.0.0	metabolic process thiamine biosynthetic process sulfur compound metabolic process thiamine biosynthetic process	cytoplasm	catalytic activity lyase activity nucleotide binding
1i6bA lactotransferrin	[pdb]	1.41 0.00388	354^GLU 383^LEU 376^THR 378^GLU 379^GLU 375^SER	0.0.0.0	transport ion transport iron ion transport cellular iron ion homeostasis	extracellular region cytoplasm stored secretory granule	protein binding ferric iron binding heparin binding peptidase activity serine-type peptidase activity hydrolase activity metal ion binding
2dfaA hypothetical upf0271 protein tthb195	[pdb]	1.41 0.00388	124^THR 144^LEU 152^GLU 151^GLU 150^GLU 153^ALA	0.0.0.0	carbohydrate metabolic process		catalytic activity
2ghiB transport protein	[pdb]	1.41 0.00388	216^THR 240^LEU 48^THR 221^GLU 222^SER 50^ALA	0.0.0.0	transport transmembrane transport	integral to membrane	nucleotide binding ATP binding ATPase activity nucleoside-triphosphatase activity ATPase activity
1xesA dihydropinosylvin synthase	[pdb]	1.41 0.00388	137^THR 108^LEU 135^THR 195^GLU 194^SER 134^SER	0.0.0.0	response to stress metabolic process biosynthetic process	cytoplasm	catalytic activity acyltransferase activity transferase activity transferase activity
2qk1A protein stu2	[pdb]	1.41 0.00388	520^THR 550^ARG 556^THR 555^GLU 554^GLU 527^ALA	0.0.0.0	microtubule nucleation mitotic spindle organization in nucleus	kinetochore condensed nuclear chromosome kinetochore nucleus cytoplasm spindle pole body spindle cytoskeleton microtubule spindle microtubule cell cortex	structural constituent of cytoskeleton binding protein binding microtubule binding identical protein binding
3b6iA flavoprotein wrba	[pdb]	1.41 0.00388	158^THR 183^ARG 147^GLU 177^GLU 180^SER 145^ALA	0.0.0.0	response to oxidative stress	membrane	FMN binding oxidoreductase activity oxidoreductase activity
1x1oA nicotinate-nucleotide pyrophosphorylase	[pdb]	1.42 0.0041	184^GLU 204^ARG 211^GLU 207^GLU 208^GLU 212^ALA	0.0.0.0	metabolic process NAD biosynthetic process pyridine nucleotide biosynthetic process		catalytic activity nicotinate-nucleotide diphosphorylase (carboxylating) activity
1o12B n-acetylglucosamine-6-phosphate deacetylase	[pdb]	1.42 0.0041	183^GLU 161^LEU 155^GLU 157^GLU 159^SER 153^ALA	0.0.0.0	N-acetylglucosamine metabolic process		N-acetylglucosamine-6-phosphate deacetylase activity hydrolase activity hydrolase activity
3m2tB probable dehydrogenase	[pdb]	1.42 0.0041	317^THR 109^LEU 102^THR 104^GLU 105^GLU 101^ALA	0.0.0.0	metabolic process		catalytic activity binding oxidoreductase activity
2hj9B autoinducer 2 sensor kinase/phosphatase luxq autoinducer 2-binding periplasmic protein luxp	[pdb]	1.42 0.0041	307^HOH 215^ALA 186^SER 182^VAL 184^GLY 188^ASN	0.0.0.0	two-component signal transduction system (phosphorelay) regulation of transcription DNA-dependent signal transduction phosphorylation	plasma membrane membrane integral to membrane periplasmic space	two-component sensor activity two-component response regulator activity nucleotide binding protein histidine kinase activity phosphoprotein phosphatase activity signal transducer activity protein binding ATP binding kinase activity transferase activity transferase activity transferring phosphorus-containing groups hydrolase activity
1f00I intimin	[pdb]	1.42 0.00432	679^THR 702^LEU 668^THR 747^GLU 749^GLU 670^ALA	0.0.0.0	cell adhesion pathogenesis cell wall macromolecule catabolic process	plasma membrane cell outer membrane cell surface membrane integral to membrane	binding protein binding
2ch1C 3-hydroxykynurenine transaminase	[pdb]	1.43 0.00432	121^THR 90^LEU 110^GLU 113^GLU 112^SER 108^ALA	0.0.0.0	metabolic process		catalytic activity pyridoxal phosphate binding
1s1hK 40s ribosomal protein s9-a 40s ribosomal protein s14-a 40s ribosomal protein s5 18s ribosomal rna 40s ribosomal protein s20 40s ribosomal protein s0-a 40s ribosomal protein s3 40s ribosomal protein s23 40s ribosomal protein s15 40s ribosomal protein s29-b 40s ribosomal protein s16 40s ribosomal protein s11 40s ribosomal protein s22 40s ribosomal protein s13 elongation factor 2 40s ribosomal protein s2 40s ribosomal protein s18	[pdb]	1.43 0.00432	85^ILE 89^MET 25^SER 53^PRO 55^GLY 59^LYS	0.0.0.0	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA 5.8S rRNA LSU-rRNA) translation regulation of translational fidelity rRNA export from nucleus translation ribosome biogenesis translation maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA 5.8S rRNA LSU-rRNA) translation maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA 5.8S rRNA LSU-rRNA) rRNA processing translation ribosome biogenesis maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA 5.8S rRNA LSU-rRNA) translation translation rRNA export from nucleus translation rRNA processing rRNA export from nucleus translation ribosome biogenesis positive regulation of translational fidelity ribosomal small subunit assembly maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA 5.8S rRNA LSU-rRNA) rRNA processing translation ribosome biogenesis endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA 5.8S rRNA LSU-rRNA) rRNA export from nucleus translation ribosomal small subunit assembly maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA 5.8S rRNA LSU-rRNA) translation translation	intracellular cytoplasm ribosome small ribosomal subunit cytosolic small ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome small ribosomal subunit cytosolic small ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic small ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic small ribosomal subunit ribonucleoprotein complex 90S preribosome intracellular nucleus nucleolus cytoplasm ribosome small ribosomal subunit cytosolic small ribosomal subunit ribonucleoprotein complex 90S preribosome small-subunit processome intracellular cytoplasm ribosome small ribosomal subunit cytosolic small ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic small ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome small ribosomal subunit cytosolic small ribosomal subunit ribonucleoprotein complex 90S preribosome preribosome small subunit precursor intracellular nucleus nucleolus cytoplasm ribosome small ribosomal subunit cytosolic small ribosomal subunit ribonucleoprotein complex small-subunit processome intracellular nucleus nucleolus cytoplasm ribosome cytosolic small ribosomal subunit ribonucleoprotein complex 90S preribosome small-subunit processome intracellular cytoplasm mitochondrion ribosome cytosolic small ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic small ribosomal subunit ribonucleoprotein complex 90S preribosome intracellular cytoplasm ribosome cytosolic small ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic small ribosomal subunit ribonucleoprotein complex 90S preribosome intracellular cytoplasm ribosome small ribosomal subunit cytosolic small ribosomal subunit ribonucleoprotein complex 90S preribosome intracellular cytoplasm ribosome small ribosomal subunit cytosolic small ribosomal subunit ribonucleoprotein complex 90S preribosome cytoplasm	structural constituent of ribosome protein binding RNA binding structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome structural constituent of ribosome RNA binding structural constituent of ribosome DNA-(apurinic or apyrimidinic site) lyase activity protein binding RNA binding structural constituent of ribosome fibroblast growth factor 3 binding SSU rRNA binding mRNA binding structural constituent of ribosome protein binding nucleic acid binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding structural constituent of ribosome metal ion binding structural constituent of ribosome SSU rRNA binding RNA binding structural constituent of ribosome protein binding structural constituent of ribosome nucleotide binding RNA binding translation elongation factor activity GTPase activity protein binding GTP binding rRNA binding ribonucleoprotein binding
3d4eA putative beta-lactamase inhibitor protein	[pdb]	1.43 0.00432	62^THR 120^ARG 169^GLU 170^GLU 163^SER 165^SER	0.0.0.0
3mtjA homoserine dehydrogenase	[pdb]	1.43 0.00432	101^THR 22^LEU 305^THR 303^GLU 307^SER 308^ALA	0.0.0.0	cellular amino acid metabolic process metabolic process cellular amino acid biosynthetic process branched chain family amino acid biosynthetic process methionine biosynthetic process threonine biosynthetic process isoleucine biosynthetic process oxidation-reduction process		catalytic activity homoserine dehydrogenase activity binding oxidoreductase activity amino acid binding NADP binding
1tuaA hypothetical protein ape0754	[pdb]	1.43 0.00432	170^GLU 117^ARG 126^THR 124^GLU 123^GLU 149^ALA	0.0.0.0			RNA binding
3hdiB processing protease synthetic peptide	[pdb]	1.43 0.00432	159^THR 152^LEU 41^GLU 37^GLU 38^SER 39^ALA	0.0.0.0	proteolysis		catalytic activity metalloendopeptidase activity peptidase activity zinc ion binding metal ion binding
2olcB methylthioribose kinase	[pdb]	1.43 0.00456	147^THR 323^LEU 299^THR 298^GLU 301^SER 303^ALA	2.7.1.100	response to stress cellular amino acid biosynthetic process methionine biosynthetic process		nucleotide binding ATP binding kinase activity transferase activity S-methyl-5-thioribose kinase activity
1vqkY 50s ribosomal protein l37ae 50s ribosomal protein l22p 50s ribosomal protein l30p 50s ribosomal protein l14p 50s ribosomal protein l10e 23s ribosomal rna 5'-r(cpcp(da)(phe)*(aca))-3' 50s ribosomal protein l4e 50s ribosomal protein l24e 50s ribosomal protein l24p 50s ribosomal protein l19e 50s ribosomal protein l6p 50s ribosomal protein l2p acidic ribosomal protein p0 homolog 50s ribosomal protein l23p 50s ribosomal protein l15p 50s ribosomal protein l39e 50s ribosomal protein l13p 50s ribosomal protein l7ae 50s ribosomal protein l37e 50s ribosomal protein l5p 50s ribosomal protein l44e 50s ribosomal protein l32e 50s ribosomal protein l29p 50s ribosomal protein l15e 50s ribosomal protein l21e 50s ribosomal protein l31e 50s ribosomal protein l11p 50s ribosomal protein l18p 5s ribosomal rna 50s ribosomal protein l18e 50s ribosomal protein l3p	[pdb]	1.43 0.00456	194^GLU 227^ARG 220^GLU 218^GLU 222^GLU 224^ALA	0.0.0.0	translation translation translation translation translation translation translation translation ribosome biogenesis translation translation translation translation translation translation translation DNA repair translation translation translation translation translation translation translation translation translation translation translation translation ribosome biogenesis translation translation	intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome large ribosomal subunit ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome large ribosomal subunit ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome large ribosomal subunit ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome large ribosomal subunit ribonucleoprotein complex	RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding metal ion binding tRNA binding RNA binding structural constituent of ribosome rRNA binding tRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding nucleotide binding DNA binding RNA binding structural constituent of ribosome protein binding rRNA binding nucleotide binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding metal ion binding tRNA binding RNA binding structural constituent of ribosome rRNA binding metal ion binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome 5S rRNA binding rRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding metal ion binding RNA binding structural constituent of ribosome rRNA binding structural constituent of ribosome RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding
3ks6B glycerophosphoryl diester phosphodiesterase	[pdb]	1.43 0.00456	234^THR 3^ARG 25^THR 32^GLU 31^GLU 29^ALA	0.0.0.0	glycerol metabolic process lipid metabolic process		phosphoric diester hydrolase activity glycerophosphodiester phosphodiesterase activity
3ms0V 30s ribosomal protein s16 30s ribosomal protein s17 30s ribosomal protein s14 30s ribosomal protein s15 30s ribosomal protein s12 30s ribosomal protein s13 30s ribosomal protein s10 peptide chain release factor 1 30s ribosomal protein thx 30s ribosomal protein s18 30s ribosomal protein s19 30s ribosomal protein s11 30s ribosomal protein s8 30s ribosomal protein s9 30s ribosomal protein s4 30s ribosomal protein s5 30s ribosomal protein s6 30s ribosomal protein s7 16s rrna (1504-mer) 30s ribosomal protein s2 30s ribosomal protein s3 30s ribosomal protein s20 messenger rna (5'-r(apapupgpupap*g)-3') p-site trna-fmet	[pdb]	1.44 0.00456	198^THR 122^LEU 115^THR 118^GLU 119^GLU 195^SER	0.0.0.0	translation translation translation translation translation translation translation translation translation translation translation translation translation translation translation translation translation translation translation translation translational termination	intracellular ribosome small ribosomal subunit ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex ribosome ribonucleoprotein complex intracellular ribosome small ribosomal subunit ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome small ribosomal subunit ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome small ribosomal subunit ribonucleoprotein complex intracellular ribosome small ribosomal subunit ribonucleoprotein complex intracellular ribosome small ribosomal subunit ribonucleoprotein complex intracellular ribosome small ribosomal subunit ribonucleoprotein complex ribosome ribonucleoprotein complex intracellular ribosome small ribosomal subunit ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex cytoplasm	tRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding rRNA binding RNA binding structural constituent of ribosome RNA binding structural constituent of ribosome rRNA binding tRNA binding nucleic acid binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding metal ion binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding metal ion binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding tRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding tRNA binding RNA binding structural constituent of ribosome rRNA binding translation release factor activity translation release factor activity
1z6gA guanylate kinase	[pdb]	1.44 0.00481	72^GLU 99^LEU 83^THR 87^GLU 35^SER 37^SER	0.0.0.0	purine nucleotide metabolic process		guanylate kinase activity kinase activity transferase activity
3iwjA putative aminoaldehyde dehydrogenase	[pdb]	1.44 0.00481	271^GLU 413^LEU 406^THR 408^GLU 409^GLU 405^SER	0.0.0.0	metabolic process oxidation-reduction process		oxidoreductase activity
1tv4A monomethylamine methyltransferase mtmb1	[pdb]	1.44 0.00481	281^THR 39^LEU 274^THR 272^GLU 273^GLU 268^ALA	0.0.0.0	methanogenesis		methyltransferase activity transferase activity
1hzhH immunoglobulin light chain immunoglobulin heavy chain	[pdb]	1.44 0.00481	421^THR 472^LEU 405^GLU 407^GLU 455^SER 457^SER	0.0.0.0	immune response	extracellular region membrane fraction	antigen binding protein binding
1vgjA hypothetical protein ph0099	[pdb]	1.44 0.00481	56^GLU 43^LEU 110^GLU 106^GLU 108^GLU 112^ALA	0.0.0.0	RNA metabolic process	intracellular	catalytic activity 2'-5'-RNA ligase activity
3ig3A plxna3 protein	[pdb]	1.44 0.00481	1418^THR 1360^ARG 1414^GLU 1410^GLU 1411^SER 1413^ALA	0.0.0.0	signal transduction multicellular organismal development	intracellular membrane integral to membrane	receptor activity
2uvaJ fatty acid synthase beta subunits	[pdb]	1.44 0.00507	32^GLU 63^LEU 74^GLU 68^GLU 70^SER 71^SER	0.0.0.0
2byvE rap guanine nucleotide exchange factor 4	[pdb]	1.45 0.00507	129^THR 84^LEU 65^GLU 62^GLU 134^GLU 132^SER	0.0.0.0	regulation of protein phosphorylation exocytosis signal transduction small GTPase mediated signal transduction heart development positive regulation of smooth muscle cell migration calcium ion-dependent exocytosis regulation of exocytosis cAMP-mediated signaling insulin secretion regulation of dendrite development negative regulation of synaptic transmission regulation of small GTPase mediated signal transduction	photoreceptor outer segment photoreceptor inner segment intracellular cytoplasm cytosol plasma membrane cAMP-dependent protein kinase complex membrane basolateral plasma membrane apical plasma membrane axon dendrite dendritic spine protein complex excitatory synapse	nucleotide binding guanyl-nucleotide exchange factor activity Ras guanyl-nucleotide exchange factor activity protein binding cAMP-dependent protein kinase regulator activity Ras GTPase binding cAMP binding protein complex binding
3i2nA wd repeat-containing protein 92	[pdb]	1.45 0.00507	131^GLU 198^ARG 127^GLU 179^GLU 180^GLU 175^ALA	0.0.0.0	apoptosis histone lysine methylation		methylated histone residue binding
1xc5A nuclear receptor corepressor 2	[pdb]	1.45 0.00507	473^THR 458^LEU 434^GLU 438^GLU 436^GLU 433^SER	0.0.0.0	negative regulation of transcription from RNA polymerase II promoter negative regulation of gene-specific transcription from RNA polymerase II promoter	nucleus nuclear body transcriptional repressor complex nucleolus	DNA binding transcription corepressor activity Notch binding protein binding transcription repressor activity histone deacetylase binding protein N-terminus binding
3lvtA glycosyl hydrolase, family 38	[pdb]	1.45 0.00507	606^THR 557^LEU 586^THR 583^GLU 541^SER 587^ALA	0.0.0.0	carbohydrate metabolic process mannose metabolic process		catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds alpha-mannosidase activity zinc ion binding mannosidase activity hydrolase activity
3d1lA putative nadp oxidoreductase bf3122	[pdb]	1.45 0.00533	56^THR 47^LEU 40^THR 42^GLU 43^SER 38^SER	0.0.0.0	metabolic process		catalytic activity binding
1m5sB formylmethanofuran--tetrahydromethanopterinformyltransferase	[pdb]	1.45 0.00533	1078^THR 1091^ARG 1082^GLU 1085^GLU 1086^GLU 1083^ALA	2.3.1.101	one-carbon metabolic process methanogenesis	cytoplasm	acyltransferase activity transferase activity formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity
2edvA ferm and pdz domain-containing protein 1	[pdb]	1.45 0.00533	34^THR 65^LEU 29^GLU 68^GLU 66^SER 30^SER	0.0.0.0		cytoplasm cytosol cytoskeleton plasma membrane membrane	protein binding
3i33A heat shock-related 70 kda protein 2	[pdb]	1.45 0.00533	247^GLU 272^ARG 298^THR 286^GLU 284^SER 299^SER	0.0.0.0	response to stress response to unfolded protein male meiosis spermatid development	mitochondrion cell surface	nucleotide binding protein binding ATP binding unfolded protein binding
1mwwA hypothetical protein hi1388.1	[pdb]	1.45 0.00533	60^THR 78^LEU 87^GLU 85^GLU 84^SER 94^ALA	0.0.0.0
3porA porin	[pdb]	1.45 0.00533	182^GLU 165^LEU 106^THR 80^GLU 79^SER 151^ALA	0.0.0.0	transport ion transport	plasma membrane cell outer membrane membrane integral to membrane pore complex	transporter activity porin activity
2ieeB probable abc transporter extracellular-bindingprotein yckb	[pdb]	1.45 0.00533	69^GLU 211^LEU 47^THR 52^GLU 50^GLU 35^SER	0.0.0.0	transport	plasma membrane membrane outer membrane-bounded periplasmic space	transporter activity
2yquA 2-oxoglutarate dehydrogenase e3 component	[pdb]	1.46 0.00533	124^THR 106^ARG 110^THR 33^GLU 31^GLU 111^ALA	0.0.0.0	cell redox homeostasis oxidation-reduction process	cytoplasm	dihydrolipoyl dehydrogenase activity oxidoreductase activity flavin adenine dinucleotide binding
1ixeD citrate synthase	[pdb]	1.46 0.00561	241^GLU 291^LEU 297^GLU 296^GLU 295^GLU 298^ALA	0.0.0.0	cellular carbohydrate metabolic process	cytoplasm	transferase activity transferase activity
2ag5B dehydrogenase/reductase (sdr family) member 6	[pdb]	1.46 0.00561	179^THR 220^LEU 213^THR 215^GLU 216^GLU 212^ALA	1.1.1.30	fatty acid beta-oxidation transport ion transport iron ion transport metabolic process siderophore biosynthetic process heme metabolic process iron ion homeostasis oxidation-reduction process	cytoplasm mitochondrion	catalytic activity 3-hydroxybutyrate dehydrogenase activity binding oxidoreductase activity oxidoreductase activity acting on the CH-CH group of donors
1g6iA class i alpha-1,2-mannosidase	[pdb]	1.46 0.00561	132^GLU 338^LEU 210^THR 279^GLU 276^SER 206^ALA	3.2.1.113	protein N-linked glycosylation metabolic process ER-associated protein catabolic process	endoplasmic reticulum endoplasmic reticulum membrane membrane integral to membrane	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity calcium ion binding protein binding hydrolase activity hydrolase activity
3gyqB rrna (adenosine-2'-o-)-methyltransferase	[pdb]	1.46 0.00561	179^GLU 216^LEU 230^GLU 229^GLU 232^SER 231^ALA	2.1.1.66	RNA processing response to antibiotic		RNA binding methyltransferase activity RNA methyltransferase activity rRNA methyltransferase activity transferase activity rRNA (adenosine-2'-O-)-methyltransferase activity
3iwkH aminoaldehyde dehydrogenase	[pdb]	1.46 0.00561	271^GLU 413^LEU 406^THR 408^GLU 409^GLU 405^SER	0.0.0.0	metabolic process oxidation-reduction process		oxidoreductase activity aminobutyraldehyde dehydrogenase activity
3pieD 5'->3' exoribonuclease (xrn1)	[pdb]	1.46 0.00561	920^GLU 874^LEU 913^GLU 911^GLU 883^SER 881^SER		nucleobase	intracellular	nucleic acid binding exonuclease activity 5'-3' exonuclease activity
2p2wA citrate synthase	[pdb]	1.46 0.00561	45^THR 26^LEU 38^GLU 35^GLU 34^GLU 37^ALA	0.0.0.0	tricarboxylic acid cycle cellular carbohydrate metabolic process	cytoplasm	transferase activity transferase activity
1zq1D glutamyl-trna(gln) amidotransferase subunit d glutamyl-trna(gln) amidotransferase subunit e	[pdb]	1.46 0.00561	435^GLU 30^LEU 138^THR 163^GLU 162^GLU 139^ALA	0.0.0.0	translation regulation of translational fidelity cellular amino acid metabolic process translation	cytoplasm	nucleotide binding asparaginase activity ATP binding ligase activity nucleotide binding aminoacyl-tRNA ligase activity ATP binding ligase activity carbon-nitrogen ligase activity
3izst 60s ribosomal protein rpl16 (l13p) 60s ribosomal protein rpl14 (l14e) 60s ribosomal protein rpl10 (l10e) 60s ribosomal protein rpl35 (l29p) 60s ribosomal protein rpl22 (l22e) 60s ribosomal protein rpl27 (l27e) 60s ribosomal protein rpl37 (l37e) 60s ribosomal protein rpl12 (l11p) 60s ribosomal protein rpl8 (l7ae) 60s ribosomal protein rpl38 (l38e) 60s ribosomal protein rpl41 (l41e) 60s ribosomal protein rpl18 (l18e) 60s ribosomal protein rpl13 (l13e) 60s ribosomal protein rpl34 (l34e) 60s ribosomal protein rpl2 (l2p) 60s ribosomal protein rpl30 (l30e) 60s ribosomal protein rpl33 (l35ae) 60s acidic ribosomal protein rpp0 (l10p) 60s ribosomal protein rpl17 (l22p) 60s ribosomal protein rpl4 (l4p) 60s ribosomal protein rpl36 (l36e) 60s ribosomal protein rpl31 (l31e) 60s ribosomal protein rpl1 (l1p) 60s ribosomal protein rpl28 (l15p) 60s ribosomal protein rpl23 (l14p) 60s ribosomal protein rpl29 (l29e) 60s ribosomal protein rpl11 (l5p) 60s ribosomal protein rpl24 (l24e) 60s ribosomal protein rpl42 (l44e) 60s ribosomal protein rpl25 (l23p) 60s ribosomal protein rpl5 (l18p) 60s ribosomal protein rpl6 (l6e) 60s acidic ribosomal protein (p2) 60s ribosomal protein rpl19 (l19e) 60s ribosomal protein pl32 (l32e) 60s ribosomal protein rpl7 (l30p) 60s ribosomal protein rpl21 (l21e) 60s ribosomal protein rpl20 (l18ae) 60s acidic ribosomal protein rpp11 (p1) 60s ribosomal protein rpl26 (l24p) 60s ribosomal protein rpl39 (l39e) unknown protein 60s ribosomal protein rpl15 (l15e) 60s ribosomal protein rpl43 (l37ae) 60s ribosomal protein rpl40 (l40e) 60s ribosomal protein rpl3 (l3p) 60s ribosomal protein rpl9 (l6p)	[pdb]	1.46 0.00589	30^LYS 49^CYS 24^ARG 20^SER 22^TYR 23^ASN	0.0.0.0	translation response to antibiotic response to cycloheximide translation response to antibiotic response to cycloheximide translation translation ribosomal large subunit assembly translation translation ribosomal large subunit assembly translation translational elongation ribosome biogenesis translation translational elongation translation translational elongation translation translation translation translation translation translation translation translation translation translation translation translation translation ribosomal large subunit assembly translation translation translation regulation of translational fidelity DNA repair translation response to DNA damage stimulus translation rRNA processing translation negative regulation of translation negative regulation of nuclear mRNA splicing via spliceosome ribosomal large subunit assembly translation translation ribosome biogenesis ribosomal large subunit assembly translation ribosomal large subunit assembly translation translation translation translation maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA 5.8S rRNA LSU-rRNA) translation ribosomal large subunit assembly translation translational termination translation translation translation RNA processing translation translation ribosomal large subunit assembly	intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular nucleus cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex 90S preribosome preribosome large subunit precursor intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome large ribosomal subunit cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome large ribosomal subunit cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome large ribosomal subunit cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular nucleus cytoplasm ribosome ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome large ribosomal subunit cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex preribosome large subunit precursor intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex	structural constituent of ribosome RNA binding structural constituent of ribosome RNA binding structural constituent of ribosome structural constituent of ribosome nucleotide binding RNA binding structural constituent of ribosome rRNA binding structural constituent of ribosome structural constituent of ribosome protein binding LSU rRNA binding structural constituent of ribosome protein binding structural constituent of ribosome protein binding structural constituent of ribosome RNA binding structural constituent of ribosome rRNA binding structural constituent of ribosome protein binding transcription regulator activity structural constituent of ribosome rRNA binding structural constituent of ribosome RNA binding structural constituent of ribosome structural constituent of ribosome RNA binding structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome RNA binding structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome RNA binding structural constituent of ribosome rRNA binding structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome RNA binding structural constituent of ribosome protein binding RNA binding structural constituent of ribosome protein binding pre-mRNA 5'-splice site binding structural constituent of ribosome protein binding structural constituent of ribosome protein binding RNA binding structural constituent of ribosome RNA binding structural constituent of ribosome 5S rRNA binding rRNA binding RNA binding structural constituent of ribosome RNA binding structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome protein binding RNA binding structural constituent of ribosome rRNA binding metal ion binding structural constituent of ribosome structural constituent of ribosome metal ion binding RNA binding structural constituent of ribosome structural constituent of ribosome RNA binding structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome
3cvrA invasion plasmid antigen	[pdb]	1.46 0.00589	157^GLU 125^LEU 160^THR 163^GLU 143^GLU 140^ALA	0.0.0.0	pathogenesis	extracellular region host cell cytoplasm	protein binding ligase activity
3hylB transketolase	[pdb]	1.46 0.0059	412^GLU 118^LEU 167^GLU 162^GLU 165^SER 168^ALA	0.0.0.0	metabolic process		catalytic activity transketolase activity transferase activity
3gvyA bacterioferritin	[pdb]	1.46 0.0059	94^GLU 45^ARG 18^GLU 50^GLU 48^SER 21^ALA	0.0.0.0	iron ion transport cellular iron ion homeostasis oxidation-reduction process		ferric iron binding oxidoreductase activity metal ion binding transition metal ion binding
2q0tA putative gamma-carboxymuconolactone decarboxylase subunit	[pdb]	1.47 0.0059	84^GLU 100^LEU 92^THR 94^GLU 95^GLU 91^ALA	0.0.0.0