The LabelHash Server

Top 150 matches

For each match you can click on the "[pdb]" link to download a PDB file with the matching chain aligned with the motif.
Download a zip file with PDB files for all the matches and the motif itself.

PDB ID		LRMSD / p-value	Matching Residues	EC	Gene Ontology annotations
PDB ID		LRMSD / p-value	Matching Residues	EC	Biological Process	Cellular Component	Molecular Function
1jg4A protein-l-isoaspartate o-methyltransferase	[pdb]	0.117 1.89e-05	97^GLU 99^GLY 101^GLY 160^ASP 179^LEU 183^GLY	2.1.1.77	protein modification process	cytoplasm	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity methyltransferase activity transferase activity
2yxeB protein-l-isoaspartate o-methyltransferase	[pdb]	0.194 5.18e-05	83^GLU 85^GLY 87^GLY 148^ASP 167^LEU 171^GLY	2.1.1.77	protein modification process	cytoplasm	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity methyltransferase activity transferase activity
1vbfC 231aa long hypothetical protein-l-isoaspartate o-methyltransferase	[pdb]	0.288 0.000124	76^GLU 78^GLY 80^GLY 136^ASP 155^LEU 159^GLY	0.0.0.0	protein modification process		protein-L-isoaspartate (D-aspartate) O-methyltransferase activity methyltransferase activity transferase activity
3evzA methyltransferase	[pdb]	0.305 0.000155	86^GLU 88^GLY 90^GLY 150^ASP 194^LEU 198^GLY	0.0.0.0			methyltransferase activity
1r18A protein-l-isoaspartate(d-aspartate)-o-methyltransferase	[pdb]	0.322 0.000179	84^ASP 86^GLY 88^GLY 159^ASN 178^LEU 182^GLY	2.1.1.77	protein modification process	cytoplasm	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity methyltransferase activity transferase activity
1o54A sam-dependent o-methyltransferase	[pdb]	0.325 0.000192	106^ASP 108^GLY 110^GLY 171^ASP 191^LEU 195^GLY	0.0.0.0	tRNA methylation		tRNA (adenine-N1-)-methyltransferase activity
3lbfD protein-l-isoaspartate o-methyltransferase	[pdb]	0.326 0.000192	81^GLU 83^GLY 85^GLY 143^ASP 162^LEU 166^GLY		protein modification process	cytoplasm	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity methyltransferase activity transferase activity
3ofkD nodulation protein s	[pdb]	0.382 0.000331	50^GLU 52^GLY 54^ALA 109^ASP 137^LEU 141^GLY		oligosaccharide biosynthetic process nodulation		methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity transferase activity
3lgaC sam-dependent methyltransferase	[pdb]	0.396 0.000375	99^GLU 101^GLY 103^GLY 164^ASP 184^LEU 188^GLY	0.0.0.0	tRNA methylation		methyltransferase activity tRNA (adenine-N1-)-methyltransferase activity transferase activity
1dl5B protein-l-isoaspartate o-methyltransferase	[pdb]	0.401 0.000375	81^GLU 83^GLY 85^GLY 146^ASP 165^LEU 169^GLY	2.1.1.77	protein modification process	cytoplasm	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity methyltransferase activity transferase activity
3e23A uncharacterized protein rpa2492	[pdb]	0.401 0.000375	49^GLU 51^GLY 53^GLY 104^ASP 131^LEU 135^GLY	0.0.0.0	metabolic process		methyltransferase activity
3ihtA s-adenosyl-l-methionine methyl transferase	[pdb]	0.41 0.000423	45^GLU 47^GLY 49^GLY 107^SER 136^LEU 140^GLY	0.0.0.0
1i1nA protein-l-isoaspartate o-methyltransferase	[pdb]	0.416 0.000449	83^ASP 85^GLY 87^GLY 153^ASP 172^LEU 176^GLY	2.1.1.77	protein modification process protein methylation protein repair	cytoplasm endoplasmic reticulum	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity protein binding methyltransferase activity transferase activity identical protein binding
3grzA ribosomal protein l11 methyltransferase	[pdb]	0.436 0.000506	182^ASP 184^GLY 186^GLY 243^ASP 265^LEU 269^GLY	0.0.0.0	protein methylation	cytoplasm	methyltransferase activity protein methyltransferase activity transferase activity
3bgvA mrna cap guanine-n7 methyltransferase	[pdb]	0.442 0.000536	39^ASP 41^GLY 43^GLY 115^ASP 144^LEU 148^GLY	2.1.1.56	mRNA capping mRNA processing	nucleus nucleoplasm	RNA binding mRNA (guanine-N7-)-methyltransferase activity methyltransferase activity transferase activity
1i9gA hypothetical protein rv2118c	[pdb]	0.453 0.000601	105^GLU 107^GLY 109^GLY 173^ASP 193^LEU 197^GLY	0.0.0.0	tRNA methylation protein homotetramerization	plasma membrane	methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity tRNA (adenine-N1-)-methyltransferase activity transferase activity
3busA methyltransferase	[pdb]	0.454 0.000601	67^ASP 69^GLY 71^GLY 131^ASP 156^LEU 160^GLY	0.0.0.0	metabolic process metabolic process		methyltransferase activity transferase activity methyltransferase activity transferase activity
2nxnA ribosomal protein l11 methyltransferase 50s ribosomal protein l11	[pdb]	0.465 0.000671	126^MET 128^ALA 130^SER 186^ASP 208^LEU 212^GLY	0.0.0.0	protein methylation translation	cytoplasm ribosome ribonucleoprotein complex	methyltransferase activity protein methyltransferase activity transferase activity RNA binding structural constituent of ribosome rRNA binding
3g5lB putative s-adenosylmethionine dependentmethyltransferase	[pdb]	0.468 0.000671	48^ASP 50^GLY 52^GLY 108^ASN 133^LEU 137^GLY	0.0.0.0	metabolic process		methyltransferase activity
3orhC guanidinoacetate n-methyltransferase	[pdb]	0.486 0.000786	66^GLU 68^GLY 70^GLY 130^ASP 160^LEU 164^GLY	2.1.1.2	creatine metabolic process creatine biosynthetic process muscle contraction	cytosol	methyltransferase activity transferase activity guanidinoacetate N-methyltransferase activity
3dtnB putative methyltransferase mm_2633	[pdb]	0.491 0.000787	48^ASP 50^GLY 52^GLY 109^ASP 136^LEU 140^GLY	0.0.0.0	metabolic process		methyltransferase activity
2vdvE trna (guanine-n(7)-)-methyltransferase	[pdb]	0.491 0.000787	101^ASP 103^GLY 105^GLY 176^SER 209^LEU 213^GLY	2.1.1.33	tRNA modification tRNA processing tRNA methylation	nucleus	tRNA binding RNA binding protein binding methyltransferase activity tRNA (guanine-N7-)-methyltransferase activity transferase activity
2pbfB protein-l-isoaspartate o-methyltransferase beta-aspartate methyltransferase	[pdb]	0.493 0.000827	86^ASP 88^GLY 90^GLY 164^ASP 183^LEU 187^GLY	0.0.0.0	protein modification process		protein-L-isoaspartate (D-aspartate) O-methyltransferase activity methyltransferase activity transferase activity
3bkwB s-adenosylmethionine dependent methyltransferase	[pdb]	0.493 0.000827	48^ASP 50^GLY 52^GLY 108^ASP 133^LEU 137^GLY	0.0.0.0	metabolic process		methyltransferase activity
2zwvA probable ribosomal rna small subunitmethyltransferase	[pdb]	0.507 0.00091	239^ASP 241^GLY 243^GLY 300^ASP 330^LEU 334^GLY	0.0.0.0	rRNA modification methylation		rRNA (adenine-N6,N6-)-dimethyltransferase activity nucleic acid binding methyltransferase activity rRNA methyltransferase activity transferase activity
3e05D precorrin-6y c5,15-methyltransferase(decarboxylating)	[pdb]	0.507 0.00091	254^ASP 256^GLY 258^GLY 318^ASP 340^LEU 344^GLY	0.0.0.0	metabolic process cobalamin biosynthetic process		methyltransferase activity protein methyltransferase activity transferase activity precorrin-6Y C5,15-methyltransferase (decarboxylating) activity
3e7pA putative methyltransferase	[pdb]	0.517 0.000953	53^ASP 55^GLY 57^GLY 117^ASP 141^LEU 145^GLY	0.0.0.0	metabolic process		methyltransferase activity
1kxzC precorrin-6y methyltransferase/putativedecarboxylase	[pdb]	0.518 0.000953	39^ASP 41^GLY 43^GLY 102^ASP 124^LEU 128^GLY	0.0.0.0	cobalamin biosynthetic process		methyltransferase activity protein methyltransferase activity transferase activity
1p1cB guanidinoacetate n-methyltransferase	[pdb]	0.525 0.000997	65^GLU 67^GLY 69^GLY 129^ASP 159^LEU 163^GLY	2.1.1.2	creatine biosynthetic process S-adenosylhomocysteine metabolic process S-adenosylmethionine metabolic process		methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity transferase activity guanidinoacetate N-methyltransferase activity protein homodimerization activity
2o57D putative sarcosine dimethylglycinemethyltransferase	[pdb]	0.528 0.00104	88^ASP 90^GLY 92^GLY 152^ASP 177^LEU 181^GLY
1f3lA protein arginine methyltransferase prmt3	[pdb]	0.543 0.00113	258^ASP 260^GLY 262^GLY 321^ASP 349^LEU 353^GLY	0.0.0.0	protein methylation peptidyl-arginine methylation	intracellular cytoplasm cytosol ribosome	protein binding methyltransferase activity zinc ion binding protein methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity protein-arginine N-methyltransferase activity transferase activity protein-arginine omega-N asymmetric methyltransferase activity metal ion binding
3hnrA probable methyltransferase bt9727_4108	[pdb]	0.546 0.00113	51^GLU 53^GLY 55^GLY 108^ASP 135^LEU 139^GLY	0.0.0.0	metabolic process		methyltransferase activity transferase activity
2b25A hypothetical protein	[pdb]	0.555 0.00118	109^GLU 111^GLY 113^GLY 187^ASP 207^LEU 211^GLY	2.1.1.36	tRNA processing tRNA methylation		methyltransferase activity tRNA (adenine-N1-)-methyltransferase activity transferase activity
3b3fB histone-arginine methyltransferase carm1	[pdb]	0.556 0.00118	191^ASP 193^GLY 195^GLY 253^ASP 280^LEU 284^GLY	2.1.1.125	mRNA processing positive regulation of cell proliferation RNA splicing pathogenesis chromatin modification response to cAMP	nucleus cytoplasm	protein binding methyltransferase activity histone-arginine N-methyltransferase activity transferase activity
3g5tA trans-aconitate 3-methyltransferase	[pdb]	0.563 0.00128	42^ASP 44^GLY 46^GLY 115^ASP 139^LEU 143^GLY	2.1.1.145	metabolic process	cytoplasm cytosol	methyltransferase activity transferase activity trans-aconitate 3-methyltransferase activity
1dusA mj0882	[pdb]	0.564 0.00128	61^ASP 63^GLY 65^GLY 124^ASN 150^LEU 154^GLY	0.0.0.0			methyltransferase activity transferase activity
2e58B mnmc2	[pdb]	0.574 0.00132	102^ASP 104^GLY 106^GLY 188^ASP 216^ILE 220^GLY	0.0.0.0
1xxlB ycgj protein	[pdb]	0.577 0.00137	18^ASP 20^GLY 22^GLY 80^ASP 105^LEU 109^GLY	0.0.0.0	metabolic process		methyltransferase activity transferase activity
2nyuB putative ribosomal rna methyltransferase 2	[pdb]	0.58 0.00137	28^ASP 30^GLY 32^ALA 99^ASP 135^LEU 139^GLY	0.0.0.0	rRNA processing rRNA methylation methylation	nucleus nucleolus mitochondrion	nucleic acid binding methyltransferase activity RNA methyltransferase activity transferase activity
1oriA protein arginine n-methyltransferase 1	[pdb]	0.585 0.00142	76^ASP 78^GLY 80^GLY 139^ASP 167^LEU 171^GLY	0.0.0.0	protein methylation peptidyl-arginine methylation peptidyl-arginine methylation to asymmetrical-dimethyl arginine	nucleus cytoplasm protein complex	protein binding methyltransferase activity protein methyltransferase activity histone-arginine N-methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity [cytochrome c]-arginine N-methyltransferase activity transferase activity snoRNP binding protein-arginine omega-N monomethyltransferase activity protein-arginine omega-N asymmetric methyltransferase activity
2a14A indolethylamine n-methyltransferase	[pdb]	0.592 0.00147	61^ASP 63^GLY 65^GLY 158^ASP 187^LEU 191^GLY	2.1.1.49		cytoplasm	methyltransferase activity transferase activity amine N-methyltransferase activity
2pjdA ribosomal rna small subunit methyltransferase c	[pdb]	0.6 0.00152	202^ASP 204^GLY 206^GLY 263^ASP 293^LEU 297^GLY	2.1.1.52	rRNA processing rRNA methylation methylation rRNA base methylation	cytoplasm	nucleic acid binding methyltransferase activity rRNA (guanine-N2-)-methyltransferase activity transferase activity
1p91B ribosomal rna large subunit methyltransferase a	[pdb]	0.607 0.00157	91^ASP 93^GLY 95^GLY 150^ASP 168^VAL 172^GLY	2.1.1.51	rRNA processing metabolic process rRNA base methylation		protein binding methyltransferase activity rRNA (guanine-N1-)-methyltransferase activity transferase activity metal ion binding
2fytA protein arginine n-methyltransferase 3	[pdb]	0.608 0.00157	278^ASP 280^GLY 282^GLY 341^ASP 369^LEU 373^GLY	0.0.0.0	protein methylation biological_process	intracellular cytoplasm	methyltransferase activity zinc ion binding protein methyltransferase activity protein-arginine N-methyltransferase activity transferase activity metal ion binding
3d2lD sam-dependent methyltransferase	[pdb]	0.608 0.00157	38^ASP 40^GLY 42^GLY 97^ASP 126^LEU 130^GLY	0.0.0.0	metabolic process		methyltransferase activity transferase activity
1nkvC hypothetical protein yjhp	[pdb]	0.61 0.00157	42^ASP 44^GLY 46^GLY 105^ASP 130^LEU 134^GLY	0.0.0.0	metabolic process	membrane integral to membrane	protein binding methyltransferase activity
2zfuB cerebral protein 1	[pdb]	0.614 0.00161	314^ASP 316^GLY 318^GLY 358^ASP 382^LEU 386^GLY	0.0.0.0	chromatin silencing at rDNA rRNA processing chromatin modification	nucleus chromatin silencing complex nucleolus rDNA heterochromatin	protein binding methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity transferase activity methylated histone residue binding
1g6q2 hnrnp arginine n-methyltransferase	[pdb]	0.616 0.00161	64^ASP 66^GLY 68^GLY 127^ASP 155^LEU 159^GLY	0.0.0.0	mRNA export from nucleus protein methylation peptidyl-arginine methylation negative regulation of transcription termination DNA-dependent	nucleus cytoplasm	protein binding methyltransferase activity protein methyltransferase activity transferase activity protein-arginine omega-N monomethyltransferase activity protein-arginine omega-N asymmetric methyltransferase activity identical protein binding
3e8sA putative sam dependent methyltransferase	[pdb]	0.623 0.00166	57^ASP 59^GLY 61^GLY 117^ASP 141^LEU 145^GLY	0.0.0.0
2gs9B hypothetical protein tt1324	[pdb]	0.625 0.00166	43^GLU 45^GLY 47^GLY 98^ASP 123^LEU 127^GLY	0.0.0.0	metabolic process		methyltransferase activity
1l1eB mycolic acid synthase	[pdb]	0.641 0.0018	70^ASP 72^GLY 74^GLY 131^ASP 158^LEU 162^GLY	0.0.0.0	lipid biosynthetic process pathogenesis active evasion of host immune response S-adenosylmethionine metabolic process modulation by symbiont of host innate immunity mycolic acid biosynthetic process	cytoplasm	methyltransferase activity cyclopropane-fatty-acyl-phospholipid synthase activity transferase activity
1ri4A mrna capping enzyme	[pdb]	0.658 0.0019	70^ASP 72^GLY 74^GLY 135^ASP 164^LEU 168^GLY	2.1.1.56	mRNA capping mRNA processing	nucleus	RNA binding mRNA (guanine-N7-)-methyltransferase activity methyltransferase activity transferase activity
3ccfB cyclopropane-fatty-acyl-phospholipid synthase	[pdb]	0.662 0.00194	44^ASP 46^GLY 48^GLY 100^ASP 125^LEU 129^GLY	0.0.0.0	metabolic process		methyltransferase activity transferase activity trans-aconitate 2-methyltransferase activity
1xtpA lmaj004091aaa	[pdb]	0.664 0.00194	99^ASP 101^GLY 103^GLY 160^ASP 187^LEU 191^GLY	0.0.0.0			methyltransferase activity
3dlcA putative s-adenosyl-l-methionine-dependentmethyltransferase	[pdb]	0.665 0.00194	48^ASP 50^GLY 52^GLY 112^ASP 137^LEU 141^GLY	0.0.0.0	metabolic process		methyltransferase activity transferase activity
1vlmB sam-dependent methyltransferase	[pdb]	0.673 0.00199	41^GLU 43^GLY 45^GLY 92^ASP 117^LEU 121^GLY	0.0.0.0	metabolic process		methyltransferase activity
1kp9B cyclopropane-fatty-acyl-phospholipid synthase 1	[pdb]	0.682 0.00207	70^ASP 72^GLY 74^GLY 131^ASP 158^LEU 162^GLY	2.1.1.79	lipid biosynthetic process S-adenosylmethionine metabolic process Actinobacterium-type cell wall biogenesis mycolic acid biosynthetic process lipid biosynthetic process	cytoplasm plasma membrane cytoplasm	methyltransferase activity cyclopropane-fatty-acyl-phospholipid synthase activity transferase activity methyltransferase activity cyclopropane-fatty-acyl-phospholipid synthase activity transferase activity
2p35A trans-aconitate 2-methyltransferase	[pdb]	0.687 0.00207	36^ASP 38^GLY 40^GLY 94^ASP 119^LEU 123^GLY	2.1.1.144	metabolic process	cytoplasm	methyltransferase activity transferase activity trans-aconitate 2-methyltransferase activity
3i9fB putative type 11 methyltransferase	[pdb]	0.693 0.00211	37^ASP 39^GLY 41^GLY 91^ASP 116^LEU 120^GLY	0.0.0.0	metabolic process		methyltransferase activity
2ex4A adrenal gland protein ad-003	[pdb]	0.694 0.00211	68^ASP 70^GLY 72^GLY 131^ASP 158^LEU 162^GLY	0.0.0.0	spindle organization chromosome segregation N-terminal peptidyl-proline dimethylation N-terminal peptidyl-serine dimethylation N-terminal peptidyl-serine trimethylation	nucleus	protein binding methyltransferase activity protein methyltransferase activity transferase activity
2gh1A methyltransferase	[pdb]	0.703 0.00216	45^ASP 47^GLY 49^GLY 108^ASP 133^VAL 137^GLY	0.0.0.0			methyltransferase activity transferase activity
3o8kA fascin	[pdb]	0.704 0.00219	1492^GLU 1390^GLY 1488^ALA 1259^SER 1142^VAL 1257^GLU	0.0.0.0	cell proliferation actin cytoskeleton organization actin filament bundle assembly	cytoplasm actin cytoskeleton filopodium	actin binding protein binding protein binding bridging
2i62C nicotinamide n-methyltransferase	[pdb]	0.715 0.00223	62^ASP 64^GLY 66^GLY 159^ASP 188^LEU 192^GLY	2.1.1.1		cytoplasm	nicotinamide N-methyltransferase activity methyltransferase activity transferase activity
2gq8A oxidoreductase, fmn-binding	[pdb]	0.715 0.00223	189^ASN 185^GLY 242^GLY 215^ASP 218^VAL 216^GLU	0.0.0.0	metabolic process		catalytic activity FMN binding oxidoreductase activity
1tw2B carminomycin 4-o-methyltransferase	[pdb]	0.719 0.00227	184^ASP 186^GLY 188^GLY 246^ASP 273^LEU 277^GLY	0.0.0.0	antibiotic biosynthetic process		nucleotide binding ATP binding methyltransferase activity O-methyltransferase activity transferase activity
2iipD nicotinamide n-methyltransferase	[pdb]	0.731 0.00231	61^ASP 63^GLY 65^GLY 158^ASP 187^LEU 191^GLY	2.1.1.1		cytoplasm	nicotinamide N-methyltransferase activity methyltransferase activity transferase activity
3mggB methyltransferase	[pdb]	0.754 0.00245	41^GLU 43^GLY 45^GLY 105^ASP 130^LEU 134^GLY	0.0.0.0	metabolic process		methyltransferase activity transferase activity
1xdsB protein rdmb	[pdb]	0.757 0.00245	188^ASP 190^GLY 192^GLY 250^ASP 277^LEU 281^GLY				O-methyltransferase activity
1tpyA methoxy mycolic acid synthase 2	[pdb]	0.758 0.00245	70^ASP 72^GLY 74^GLY 131^ASP 158^LEU 162^GLY	0.0.0.0	lipid biosynthetic process Actinobacterium-type cell wall biogenesis mycolic acid biosynthetic process	plasma membrane	methyltransferase activity cyclopropane-fatty-acyl-phospholipid synthase activity transferase activity
1z45A gal10 bifunctional protein	[pdb]	0.762 0.00248	111^ASN 114^GLY 118^LEU 100^SER 103^ILE 99^GLU	5.1.3.3, 5.1.3.2	carbohydrate metabolic process galactose metabolic process metabolic process galactose catabolic process via UDP-galactose cellular metabolic process	soluble fraction	catalytic activity UDP-glucose 4-epimerase activity aldose 1-epimerase activity binding isomerase activity carbohydrate binding coenzyme binding
3egeA putative methyltransferase from antibioticbiosynthesis pathway	[pdb]	0.776 0.00254	39^ASP 41^GLY 43^GLY 95^ASP 120^ILE 123^GLY	0.0.0.0	metabolic process		methyltransferase activity
1yzhA trna (guanine-n(7)-)-methyltransferase	[pdb]	0.795 0.00263	44^GLU 46^GLY 48^GLY 110^ASP 143^LEU 147^GLY	2.1.1.33	tRNA modification tRNA processing		methyltransferase activity tRNA (guanine-N7-)-methyltransferase activity transferase activity
3bigA fructose-1,6-bisphosphatase class ii glpx	[pdb]	0.81 0.00268	225^ASP 126^GLY 129^ALA 277^ASN 279^ILE 107^GLY	3.1.3.11	carbohydrate metabolic process glycerol metabolic process	cytoplasm	hydrolase activity manganese ion binding fructose 1,6-bisphosphate 1-phosphatase activity
2p8jA s-adenosylmethionine-dependent methyltransferase	[pdb]	0.821 0.00271	28^ASP 30^GLY 32^GLY 90^SER 117^LEU 121^GLY	0.0.0.0	metabolic process		methyltransferase activity transferase activity
3ky9A proto-oncogene vav	[pdb]	0.824 0.00274	542^GLN 543^GLY 553^ALA 377^ASN 380^LEU 378^GLU		apoptosis induction of apoptosis by extracellular signals regulation of Rho protein signal transduction	intracellular cytosol plasma membrane	sequence-specific DNA binding transcription factor activity guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity protein binding metal ion binding
3o8oH 6-phosphofructokinase subunit beta 6-phosphofructokinase subunit alpha	[pdb]	0.855 0.00285	864^ASP 599^GLY 859^LEU 915^SER 912^VAL 914^GLY		glycolysis proton transport glycolysis proton transport	cytoplasm mitochondrion 6-phosphofructokinase complex cytoplasm mitochondrion 6-phosphofructokinase complex	nucleotide binding 6-phosphofructokinase activity protein binding ATP binding kinase activity transferase activity metal ion binding proton-transporting ATPase activity rotational mechanism nucleotide binding 6-phosphofructokinase activity protein binding ATP binding kinase activity transferase activity
3p9iA caffeic acid o-methyltransferase	[pdb]	0.865 0.00291	203^ASP 205^GLY 207^GLY 257^ASP 284^LEU 288^GLY	0.0.0.0			methyltransferase activity O-methyltransferase activity catechol O-methyltransferase activity transferase activity protein dimerization activity
2vrwB proto-oncogene vav ras-related c3 botulinum toxin substrate 1	[pdb]	0.865 0.00291	542^GLN 543^GLY 553^ALA 377^ASN 380^LEU 378^GLU	0.0.0.0	apoptosis cellular component movement inflammatory response cell adhesion cell-matrix adhesion small GTPase mediated signal transduction induction of apoptosis by extracellular signals response to wounding anatomical structure morphogenesis regulation of hydrogen peroxide metabolic process positive regulation of lamellipodium assembly lamellipodium assembly actin filament polymerization ruffle organization positive regulation of Rho protein signal transduction negative regulation of receptor-mediated endocytosis localization within membrane regulation of respiratory burst regulation of Rho protein signal transduction	intracellular cytosol plasma membrane membrane melanosome intracellular	nucleotide binding GTPase activity protein binding GTP binding enzyme binding GTP-dependent protein binding thioesterase binding guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity protein binding metal ion binding
2uveB exopolygalacturonase	[pdb]	0.871 0.00291	272^ASN 219^GLY 217^LEU 304^ASP 301^VAL 303^GLU	0.0.0.0
3m1tA putative phosphohydrolase	[pdb]	0.872 0.00294	201^GLN 215^GLY 247^GLY 177^ASN 139^ILE 141^GLU	0.0.0.0
2d80A phb depolymerase	[pdb]	0.874 0.00294	282^GLN 226^GLY 212^ALA 40^SER 38^LEU 42^GLY	0.0.0.0	carbohydrate metabolic process	extracellular region	hydrolase activity hydrolyzing O-glycosyl compounds hydrolase activity
3cggB sam-dependent methyltransferase	[pdb]	0.893 0.00305	51^ASP 53^GLY 55^GLY 108^ASP 136^LEU 140^GLY	0.0.0.0	metabolic process metabolic process		methyltransferase activity transferase activity methyltransferase activity transferase activity
2ft3E biglycan	[pdb]	0.908 0.00313	132^ASP 155^GLY 182^ALA 88^ASN 85^LEU 63^ASN	0.0.0.0	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan	extracellular region proteinaceous extracellular matrix cell surface transport vesicle extracellular matrix sarcolemma intracellular part	protein binding glycosaminoglycan binding extracellular matrix binding
3glmC glutaconyl-coa decarboxylase subunit a	[pdb]	0.911 0.00313	149^ASN 197^GLY 152^GLY 275^ASP 278^VAL 274^ASN	0.0.0.0			ligase activity
2fgeB nonspecific peptide aaltra zinc metalloprotease (insulinase family)	[pdb]	0.915 0.00318	670^GLN 605^GLY 609^LEU 743^SER 741^ILE 740^GLY	0.0.0.0	proteolysis response to cadmium ion protein maturation by peptide bond cleavage	mitochondrion mitochondrial matrix chloroplast plastid chloroplast stroma chloroplast envelope apoplast	catalytic activity metalloendopeptidase activity peptidase activity metallopeptidase activity zinc ion binding hydrolase activity metal ion binding
3gybB transcriptional regulators (laci-familytranscriptional regulatory protein)	[pdb]	0.916 0.00318	242^ASN 268^GLY 282^LEU 186^SER 190^LEU 187^GLY		regulation of transcription	intracellular	DNA binding sequence-specific DNA binding transcription factor activity
3hccA phenylethanolamine n-methyltransferase	[pdb]	0.918 0.00318	77^ASP 79^GLY 81^GLY 176^ASP 205^LEU 209^GLY	2.1.1.28	catecholamine biosynthetic process	cytosol	phenylethanolamine N-methyltransferase activity methyltransferase activity transferase activity
2bcjQ guanine nucleotide-binding protein g(i)/g(s)/g(t) beta subunit 1 g alpha i1, guanine nucleotide-binding proteing(q), alpha subunit guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-2 subunit g-protein coupled receptor kinase 2	[pdb]	0.938 0.00333	209^GLN 207^GLY 188^GLY 242^SER 238^VAL 245^GLU	0.0.0.0	signal transduction G-protein coupled receptor protein signaling pathway cell proliferation regulation of the force of heart contraction desensitization of G-protein coupled receptor protein signaling pathway G-protein coupled receptor internalization negative regulation of the force of heart contraction by chemical signal protein phosphorylation intracellular protein transport signal transduction G-protein coupled receptor protein signaling pathway muscarinic acetylcholine receptor signaling pathway tachykinin receptor signaling pathway heart development regulation of signal transduction phosphorylation peptidyl-serine phosphorylation peptidyl-threonine phosphorylation negative regulation of striated muscle contraction cardiac muscle contraction signal transduction G-protein coupled receptor protein signaling pathway negative regulation of synaptic transmission skeletal system development regulation of action potential protein ADP-ribosylation signal transduction G-protein coupled receptor protein signaling pathway activation of adenylate cyclase activity by G-protein signaling pathway glutamate signaling pathway heart development behavior post-embryonic development neuron remodeling forebrain neuron development embryonic digit morphogenesis regulation of melanocyte differentiation developmental pigmentation activation of phospholipase C activity by dopamine receptor signaling pathway signal transduction G-protein coupled receptor protein signaling pathway activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger cell proliferation sensory perception of taste	Golgi apparatus heterotrimeric G-protein complex plasma membrane membrane membrane fraction cytoplasm cytosol membrane membrane fraction cytoplasm Golgi apparatus heterotrimeric G-protein complex plasma membrane membrane raft membrane fraction heterotrimeric G-protein complex plasma membrane photoreceptor outer segment heterotrimeric G-protein complex	GTPase activity signal transducer activity nucleotide binding protein kinase activity protein serine/threonine kinase activity G-protein coupled receptor kinase activity signal transducer activity protein binding ATP binding kinase activity transferase activity alpha-2A adrenergic receptor binding Edg-2 lysophosphatidic acid receptor binding beta-adrenergic receptor kinase activity nucleotide binding GTPase activity signal transducer activity protein binding GTP binding guanyl nucleotide binding metabotropic serotonin receptor binding nucleotide binding GTPase activity signal transducer activity GTPase activator activity protein binding GTP binding guanyl nucleotide binding GTPase activity signal transducer activity
3ifeA peptidase t	[pdb]	0.953 0.00346	32^GLN 36^GLY 38^LEU 20^ASN 178^ILE 21^GLU	3.4.11.4	proteolysis peptide metabolic process metabolic process	cytoplasm	aminopeptidase activity protein binding peptidase activity metallopeptidase activity zinc ion binding hydrolase activity tripeptide aminopeptidase activity metal ion binding
2qm1D glucokinase	[pdb]	0.957 0.00354	114^ASP 308^GLY 307^ALA 75^SER 83^VAL 85^GLY	0.0.0.0	glycolysis	cytoplasm	glucokinase activity kinase activity
3k81C mp18 rna editing complex protein single strand antibody vhh domain	[pdb]	0.959 0.00354	121^SER 76^ASN 78^MET 24^VAL 99^LEU 23^VAL				single-stranded DNA binding
2p4sA purine nucleoside phosphorylase	[pdb]	0.96 0.00354	300^ASP 298^GLY 297^LEU 213^ASP 272^LEU 271^GLU	0.0.0.0	nucleobase nucleoside		catalytic activity purine-nucleoside phosphorylase activity transferase activity transferase activity transferring glycosyl groups
2ix8A elongation factor 3a	[pdb]	0.961 0.00354	1711^ASN 1715^GLY 1771^ALA 1702^ASN 1965^VAL 1700^GLY	0.0.0.0	translation translational elongation translational termination	cytoplasm ribosome cytosolic ribosome	nucleotide binding RNA binding translation elongation factor activity binding protein binding ATP binding ATPase activity nucleoside-triphosphatase activity rRNA binding
1iyxB enolase	[pdb]	0.966 0.00362	342^GLN 344^GLY 111^LEU 314^ASP 316^LEU 313^GLY	4.2.1.11	glycolysis	phosphopyruvate hydratase complex extracellular region cytoplasm cell surface	magnesium ion binding phosphopyruvate hydratase activity lyase activity metal ion binding
1bvoA transcription factor gambif1 dna duplex	[pdb]	0.967 0.00362	150^GLN 148^GLY 73^GLY 156^ASP 161^LEU 159^GLU	0.0.0.0	regulation of transcription	nucleus	sequence-specific DNA binding transcription factor activity
1yu0A major tropism determinant (mtd-p1)	[pdb]	0.97 0.00362	192^ASP 373^GLY 371^ALA 163^ASN 167^LEU 164^GLU	0.0.0.0			binding
2qyoB o-methyltransferase	[pdb]	0.974 0.00371	199^ASP 201^GLY 203^GLY 253^ASP 280^VAL 287^GLY	0.0.0.0			methyltransferase activity O-methyltransferase activity protein dimerization activity
2xzlA 5- r(upupupupupupupup*u) -3 atp-dependent helicase nam7	[pdb]	0.979 0.00381	501^ASN 504^GLY 507^ALA 492^SER 490^VAL 491^GLU		nuclear-transcribed mRNA catabolic process nonsense-mediated decay nuclear-transcribed mRNA catabolic process regulation of translational termination intracellular mRNA localization protein ubiquitination chromatin silencing at silent mating-type cassette nuclear-transcribed mRNA catabolic process	nucleus cytoplasm polysome mitochondrion	nucleotide binding nucleic acid binding DNA binding ATP-dependent RNA helicase activity helicase activity protein binding ATP binding RNA-dependent ATPase activity zinc ion binding hydrolase activity nucleoside-triphosphatase activity metal ion binding
1fzdE fibrinogen-420	[pdb]	0.981 0.00381	797^ASN 800^GLY 821^GLY 762^ASN 734^LEU 763^ASN	0.0.0.0	signal transduction blood coagulation platelet activation protein polymerization response to calcium ion	extracellular region fibrinogen complex extracellular space plasma membrane external side of plasma membrane platelet alpha granule platelet alpha granule lumen	receptor binding protein binding protein binding bridging
3f6tA aspartate aminotransferase	[pdb]	0.988 0.00391	470^GLN 490^GLY 35^LEU 467^ASN 464^LEU 466^ASN	0.0.0.0	biosynthetic process		catalytic activity L-aspartate:2-oxoglutarate aminotransferase activity transaminase activity transferase activity transferase activity transferring nitrogenous groups
1fp1D isoliquiritigenin 2'-o-methyltransferase	[pdb]	0.989 0.00391	215^ASP 217^GLY 219^GLY 269^ASP 296^LEU 300^GLY	0.0.0.0			methyltransferase activity O-methyltransferase activity transferase activity protein dimerization activity
3lqbA loc792177 protein	[pdb]	0.989 0.00391	102^ASN 106^GLY 2^ALA 94^SER 38^ILE 40^ASN	0.0.0.0	proteolysis		metalloendopeptidase activity peptidase activity metallopeptidase activity zinc ion binding hydrolase activity metal ion binding
1jbqD cystathionine beta-synthase	[pdb]	0.995 0.00402	149^ASN 151^GLY 154^LEU 349^SER 303^VAL 348^GLY	4.2.1.22	cysteine biosynthetic process from serine L-serine metabolic process L-serine catabolic process metabolic process cellular amino acid biosynthetic process cysteine biosynthetic process via cystathionine cysteine biosynthetic process L-cysteine catabolic process homocysteine catabolic process homocysteine metabolic process hydrogen sulfide biosynthetic process	nucleus nucleolus cytoplasm cytosol intracellular membrane-bounded organelle	catalytic activity cystathionine beta-synthase activity protein binding lyase activity enzyme binding heme binding pyridoxal phosphate binding ubiquitin protein ligase binding identical protein binding protein homodimerization activity metal ion binding
2be1A serine/threonine-protein kinase/endoribonucleaseire1 peptide	[pdb]	0.998 0.00402	127^ASP 130^GLY 154^LEU 348^SER 142^ILE 140^GLY	2.7.11.1	inositol metabolic process mRNA processing protein phosphorylation response to unfolded protein endoplasmic reticulum unfolded protein response fungal-type cell wall organization	nucleus endoplasmic reticulum endoplasmic reticulum membrane membrane integral to membrane	nucleotide binding catalytic activity endoribonuclease activity protein kinase activity protein serine/threonine kinase activity ATP binding kinase activity transferase activity hydrolase activity endoribonuclease activity producing 5'-phosphomonoesters identical protein binding protein homodimerization activity metal ion binding
3kgdA rna 3'-terminal phosphate cyclase	[pdb]	1 0.00413	126^ASP 124^GLY 97^GLY 238^SER 196^VAL 195^GLU	0.0.0.0	RNA processing	nucleoplasm cytoplasm	nucleotide binding catalytic activity RNA-3'-phosphate cyclase activity ATP binding ligase activity ligase activity
1zgaA isoflavanone 4'-o-methyltransferase'	[pdb]	1 0.00413	205^ASP 207^GLY 209^GLY 259^ASP 286^ILE 293^GLY	0.0.0.0			methyltransferase activity O-methyltransferase activity transferase activity protein dimerization activity
3a5qB benzalacetone synthase	[pdb]	1.01 0.00426	373^GLU 161^GLY 164^LEU 271^ASN 267^LEU 270^ASN	0.0.0.0	metabolic process biosynthetic process		catalytic activity acyltransferase activity transferase activity transferase activity
1kcwA ceruloplasmin	[pdb]	1.01 0.00426	971^GLU 969^GLY 902^LEU 632^ASN 565^VAL 631^GLY	1.16.3.1	transport ion transport copper ion transport cellular iron ion homeostasis oxidation-reduction process	extracellular region extracellular space	ferroxidase activity copper ion binding oxidoreductase activity metal ion binding chaperone binding
1ru4A pectate lyase	[pdb]	1.01 0.0044	299^ASP 275^GLY 281^GLY 317^ASN 294^VAL 292^GLY	4.2.2.2		extracellular region extracellular region	lyase activity pectate lyase activity lyase activity pectate lyase activity
2hxoA putative tetr-family transcriptional regulator	[pdb]	1.01 0.0044	163^ASN 161^GLY 108^ALA 180^ASP 183^LEU 181^GLU	0.0.0.0	regulation of transcription		DNA binding sequence-specific DNA binding transcription factor activity specific transcriptional repressor activity transcription regulator activity
1qhnA chloramphenicol phosphotransferase	[pdb]	1.01 0.0044	55^GLU 53^GLY 52^GLY 59^ASP 137^VAL 139^GLY	0.0.0.0	response to antibiotic		nucleotide binding ATP binding kinase activity transferase activity
1psoE pepsin 3a pepstatin	[pdb]	1.02 0.0044	287^GLN 223^GLY 298^LEU 244^ASP 246^VAL 240^ASN	3.4.23.1	proteolysis digestion	cellular_component extracellular region	aspartic-type endopeptidase activity peptidase activity hydrolase activity
3m3wB protein kinase c and casein kinase ii substrate protein 3	[pdb]	1.02 0.0044	73^GLN 71^GLY 67^ALA 277^ASP 281^LEU 279^GLU		endocytosis negative regulation of endocytosis positive regulation of membrane protein ectodomain proteolysis	cytoplasm plasma membrane membrane trans-Golgi network	protein binding cytoskeletal protein binding
3qn3B enolase	[pdb]	1.02 0.00456	335^GLN 337^GLY 111^LEU 307^ASP 309^LEU 306^GLY		glycolysis	phosphopyruvate hydratase complex extracellular region cytoplasm cell surface	magnesium ion binding phosphopyruvate hydratase activity lyase activity metal ion binding
1fwxD nitrous oxide reductase	[pdb]	1.02 0.00456	386^ASP 330^GLY 332^GLY 91^ASP 446^ILE 92^GLY	1.7.99.6	oxidation-reduction process	membrane periplasmic space	cytochrome-c oxidase activity copper ion binding oxidoreductase activity metal ion binding nitrous-oxide reductase activity
3b89A 16s rrna methylase	[pdb]	1.02 0.00456	115^ASN 113^GLY 136^LEU 92^ASP 94^LEU 90^GLU	0.0.0.0	response to antibiotic		methyltransferase activity rRNA methyltransferase activity
1qlbA fumarate reductase iron-sulfur protein fumarate reductase flavoprotein subunit fumarate reductase cytochrome b subunit	[pdb]	1.02 0.00456	78^VAL 76^PRO 405^LEU 557^ASP 604^ILE 606^ASN	1.3.99.1	transport electron transport chain oxidation-reduction process tricarboxylic acid cycle transport electron transport chain oxidation-reduction process tricarboxylic acid cycle transport electron transport chain	respiratory chain respiratory chain plasma membrane membrane integral to membrane respiratory chain	succinate dehydrogenase activity electron carrier activity oxidoreductase activity oxidoreductase activity acting on the CH-CH group of donors flavin adenine dinucleotide binding succinate dehydrogenase activity electron carrier activity oxidoreductase activity metal ion binding iron-sulfur cluster binding 2 iron 2 sulfur cluster binding 3 iron 4 sulfur cluster binding
1kyzA caffeic acid 3-o-methyltransferase	[pdb]	1.02 0.00456	206^ASP 208^GLY 210^GLY 260^ASP 287^LEU 291^GLY	2.1.1.68	lignin biosynthetic process		methyltransferase activity O-methyltransferase activity transferase activity protein dimerization activity caffeate O-methyltransferase activity
1v8cD moad related protein	[pdb]	1.02 0.00456	153^GLU 149^GLY 122^GLY 79^ASP 5^LEU 4^ASN	0.0.0.0	sulfur compound metabolic process		threonine synthase activity lyase activity
1w99A pesticidial crystal protein cry4ba	[pdb]	1.03 0.00456	507^ASP 500^GLY 502^GLY 488^SER 491^LEU 522^GLU	0.0.0.0	defense response pathogenesis sporulation resulting in formation of a cellular spore		receptor binding
2pc8A hypothetical protein xog1	[pdb]	1.03 0.00456	305^ASN 310^GLY 316^ALA 146^ASN 26^LEU 148^GLY	3.2.1.58	carbohydrate metabolic process cellular cell wall organization metabolic process fungal-type cell wall organization	extracellular region cell surface	catalytic activity glucan exo-1,3-beta-glucosidase activity hydrolase activity hydrolyzing O-glycosyl compounds hydrolase activity hydrolase activity
2pa6B enolase	[pdb]	1.03 0.00473	342^GLN 344^GLY 118^LEU 314^ASP 316^LEU 313^GLY	4.2.1.11	glycolysis	phosphopyruvate hydratase complex extracellular region cytoplasm cell surface	magnesium ion binding phosphopyruvate hydratase activity lyase activity metal ion binding
2ckjC xanthine oxidoreductase	[pdb]	1.03 0.00473	586^GLN 114^GLY 796^GLY 93^SER 98^LEU 92^GLY	1.17.3.2, 1.17.1.4	lactation xanthine catabolic process regulation of epithelial cell differentiation oxidation-reduction process	extracellular region cytoplasm peroxisome	catalytic activity xanthine dehydrogenase activity xanthine oxidase activity binding iron ion binding electron carrier activity oxidoreductase activity molybdenum ion binding protein homodimerization activity molybdopterin cofactor binding metal ion binding flavin adenine dinucleotide binding iron-sulfur cluster binding 2 iron
1fp2A isoflavone o-methytransferase	[pdb]	1.03 0.00473	194^ASP 196^GLY 198^GLY 248^ASP 275^VAL 282^GLY	2.1.1.150			methyltransferase activity O-methyltransferase activity transferase activity isoflavone 7-O-methyltransferase activity protein dimerization activity
1ohaA acetylglutamate kinase	[pdb]	1.03 0.00473	181^ASP 184^GLY 186^LEU 16^SER 20^LEU 18^GLU	2.7.2.8	arginine biosynthetic process cellular amino acid biosynthetic process arginine biosynthetic process cellular amino acid biosynthetic process	cytoplasm cytoplasm	nucleotide binding acetylglutamate kinase activity ATP binding kinase activity transferase activity nucleotide binding acetylglutamate kinase activity ATP binding kinase activity transferase activity
2eihA alcohol dehydrogenase	[pdb]	1.03 0.00491	40^ASN 62^GLY 61^LEU 177^SER 181^VAL 176^GLY	0.0.0.0	metabolic process oxidation-reduction process		catalytic activity binding zinc ion binding oxidoreductase activity
3mgaB enterochelin esterase	[pdb]	1.03 0.00491	381^ASP 90^GLY 148^ALA 286^SER 353^VAL 311^GLY	0.0.0.0	iron ion transport	cytoplasm	iron ion binding enterochelin esterase activity
2ppvA uncharacterized protein	[pdb]	1.04 0.00491	194^ASN 10^GLY 182^LEU 162^SER 129^VAL 160^GLU	0.0.0.0
3n0tD dipeptidyl peptidase 2	[pdb]	1.04 0.00511	200^GLN 196^GLY 190^LEU 366^ASP 364^VAL 363^ASN	3.4.14.2	proteolysis	extracellular region lysosome cytosol cytoplasmic membrane-bounded vesicle cytoplasmic vesicle	aminopeptidase activity protein binding peptidase activity serine-type peptidase activity dipeptidyl-peptidase activity hydrolase activity
3bv6F metal-dependent hydrolase	[pdb]	1.04 0.00511	121^ASP 65^GLY 67^GLY 116^SER 114^LEU 143^GLY	0.0.0.0			hydrolase activity
2iobA bifunctional glutathionylspermidinesynthetase/amidase	[pdb]	1.04 0.00511	341^GLU 343^GLY 362^ALA 241^ASN 238^VAL 242^GLY	6.3.1.8, 3.5.1.78			nucleotide binding catalytic activity protein binding ATP binding glutathionylspermidine amidase activity glutathionylspermidine synthase activity hydrolase activity ligase activity
1e9iC enolase	[pdb]	1.05 0.00511	344^GLN 346^GLY 111^LEU 316^ASP 318^LEU 315^GLY	4.2.1.11	glycolysis glycolysis glycolysis glycolysis	phosphopyruvate hydratase complex extracellular region cytoplasm cytoskeleton cell surface phosphopyruvate hydratase complex extracellular region cytoplasm cytoskeleton cell surface phosphopyruvate hydratase complex extracellular region cytoplasm cytoskeleton cell surface phosphopyruvate hydratase complex extracellular region cytoplasm cytosol cytoskeleton cell surface membrane	magnesium ion binding phosphopyruvate hydratase activity lyase activity metal ion binding magnesium ion binding phosphopyruvate hydratase activity lyase activity metal ion binding magnesium ion binding phosphopyruvate hydratase activity lyase activity metal ion binding magnesium ion binding phosphopyruvate hydratase activity protein binding lyase activity identical protein binding metal ion binding
2idoC dna polymerase iii epsilon subunit hot protein	[pdb]	1.05 0.00511	32^LEU 34^ILE 11^GLN 70^GLY 74^ALA 71^SER	2.7.7.7	DNA replication DNA replication	intracellular	DNA binding DNA-directed DNA polymerase activity nucleic acid binding DNA binding DNA-directed DNA polymerase activity nuclease activity exonuclease activity protein binding transferase activity nucleotidyltransferase activity hydrolase activity metal ion binding
3js2B basic fibroblast growth factor receptor 1	[pdb]	1.05 0.00532	641^ASP 643^GLY 645^ALA 568^ASN 631^VAL 567^GLY	0.0.0.0	MAPKKK cascade skeletal system development angiogenesis ureteric bud development in utero embryonic development organ induction positive regulation of mesenchymal cell proliferation chondrocyte differentiation protein phosphorylation brain development salivary gland morphogenesis positive regulation of cell proliferation fibroblast growth factor receptor signaling pathway regulation of gene expression cell growth lung development embryonic limb morphogenesis midbrain development neuron projection development regulation of cell proliferation inner ear morphogenesis negative regulation of apoptosis paraxial mesoderm development regulation of lateral mesodermal cell fate specification cell maturation blood vessel morphogenesis generation of neurons mesenchymal cell differentiation positive regulation of cardiac muscle cell proliferation branching involved in salivary gland morphogenesis lung-associated mesenchyme development regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway	extracellular region membrane fraction plasma membrane integral to plasma membrane membrane integral to membrane	nucleotide binding protein kinase activity protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity receptor activity fibroblast growth factor receptor activity protein binding ATP binding heparin binding kinase activity transferase activity fibroblast growth factor binding
3oidD enoyl-[acyl-carrier-protein] reductase [nadph]	[pdb]	1.05 0.00532	89^ASN 17^GLY 21^ALA 157^SER 154^VAL 155^GLY	0.0.0.0	fatty acid biosynthetic process metabolic process lipid biosynthetic process oxidation-reduction process		catalytic activity enoyl-[acyl-carrier-protein] reductase (NADPH B-specific) activity binding
3abzC beta-glucosidase i	[pdb]	1.05 0.00532	345^ASN 343^GLY 385^ALA 351^SER 648^LEU 644^GLY		carbohydrate metabolic process metabolic process		hydrolase activity hydrolyzing O-glycosyl compounds beta-glucosidase activity hydrolase activity
3coxA cholesterol oxidase	[pdb]	1.05 0.00532	216^GLU 212^GLY 213^LEU 66^SER 96^LEU 94^GLY	1.1.3.6	lipid metabolic process steroid metabolic process cholesterol metabolic process oxidation-reduction process	extracellular region	oxidoreductase activity oxidoreductase activity acting on CH-OH group of donors cholesterol oxidase activity
2o3eA neurolysin	[pdb]	1.05 0.00532	486^GLN 650^GLY 647^LEU 441^SER 437^LEU 440^GLY	3.4.24.16	proteolysis	cytoplasm mitochondrion mitochondrial intermembrane space	metalloendopeptidase activity peptidase activity metallopeptidase activity hydrolase activity metal ion binding
3b7sA rsr peptide leukotriene a-4 hydrolase	[pdb]	1.05 0.00532	401^GLU 399^GLY 398^GLY 246^ASP 243^ILE 245^GLU	3.3.2.6	proteolysis leukotriene metabolic process inflammatory response response to zinc ion leukotriene biosynthetic process response to peptide hormone stimulus Type I pneumocyte differentiation	nucleus cytoplasm	catalytic activity epoxide hydrolase activity leukotriene-A4 hydrolase activity binding protein binding peptidase activity metallopeptidase activity zinc ion binding hydrolase activity metal ion binding
2o6qA variable lymphocyte receptor a	[pdb]	1.05 0.00532	237^ASN 268^GLY 273^GLY 189^ASN 186^LEU 163^GLY	0.0.0.0			receptor activity protein binding
2qltA (dl)-glycerol-3-phosphatase 1	[pdb]	1.05 0.00532	199^GLU 204^GLY 207^ALA 238^ASN 114^VAL 116^GLY	0.0.0.0	glycerol biosynthetic process response to osmotic stress metabolic process	nucleus cytoplasm	glycerol-1-phosphatase activity catalytic activity protein binding hydrolase activity
1ryeB glucose-fructose oxidoreductase	[pdb]	1.05 0.00532	351^GLN 349^GLY 346^GLY 370^ASN 233^VAL 232^GLU	1.1.99.28	metabolic process oxidation-reduction process	periplasmic space	catalytic activity binding oxidoreductase activity glucose-fructose oxidoreductase activity
2j6lA aldehyde dehydrogenase family 7 member a1	[pdb]	1.06 0.00556	480^GLU 482^GLY 466^GLY 244^SER 242^LEU 162^GLY	1.2.1.31	cellular aldehyde metabolic process sensory perception of sound metabolic process oxidation-reduction process	cellular_component nucleus cytoplasm mitochondrion cytosol	aldehyde dehydrogenase (NAD) activity L-aminoadipate-semialdehyde dehydrogenase activity betaine-aldehyde dehydrogenase activity oxidoreductase activity
1yo8A thrombospondin-2	[pdb]	1.06 0.00556	1004^GLU 1148^GLY 868^GLY 955^SER 947^VAL 956^GLU	0.0.0.0	cell adhesion	extracellular region platelet alpha granule lumen	structural molecule activity calcium ion binding protein binding heparin binding
3czoC histidine ammonia-lyase	[pdb]	1.06 0.00556	120^ASP 230^GLY 232^ALA 191^ASP 155^VAL 193^ASN	0.0.0.0	histidine metabolic process biosynthetic process		catalytic activity histidine ammonia-lyase activity lyase activity ammonia-lyase activity
1tvnA cellulase	[pdb]	1.06 0.00556	255^ASN 23^GLY 55^LEU 227^ASN 234^VAL 198^GLY	0.0.0.0	carbohydrate metabolic process cell adhesion metabolic process	extracellular region	catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds calcium ion binding cellulase activity hydrolase activity hydrolase activity acting on glycosyl bonds
3cwcA putative glycerate kinase 2	[pdb]	1.06 0.00581	46^GLU 135^GLY 95^GLY 8^ASP 304^VAL 292^GLU	0.0.0.0	organic acid phosphorylation		glycerate kinase activity kinase activity
1bwlA protein (nadph dehydrogenase 1)	[pdb]	1.06 0.00581	200^GLN 195^GLY 121^ALA 219^ASN 217^ILE 218^GLU	1.6.99.1	metabolic process oxidation-reduction process		catalytic activity NADPH dehydrogenase activity FMN binding oxidoreductase activity
1l1jA heat shock protease htra	[pdb]	1.07 0.00581	221^ASN 207^GLY 83^GLY 198^ASP 233^LEU 232^ASN	0.0.0.0	proteolysis response to stress		catalytic activity serine-type endopeptidase activity protein binding peptidase activity
2nupB vesicle-trafficking protein sec22b protein transport protein sec23a protein transport protein sec24a	[pdb]	1.07 0.00581	621^GLN 617^GLY 645^GLY 628^SER 685^VAL 631^GLY	0.0.0.0	transport ER to Golgi vesicle-mediated transport protein transport vesicle-mediated transport transport intracellular protein transport ER to Golgi vesicle-mediated transport protein transport cellular membrane organization vesicle-mediated transport transport intracellular protein transport ER to Golgi vesicle-mediated transport protein transport cellular membrane organization vesicle-mediated transport	Golgi membrane endoplasmic reticulum endoplasmic reticulum membrane ER-Golgi intermediate compartment Golgi apparatus membrane integral to membrane ER-Golgi intermediate compartment membrane melanosome Golgi membrane cytoplasm endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus membrane COPII vesicle coat perinuclear region of cytoplasm Golgi membrane endoplasmic reticulum Golgi apparatus cytosol membrane COPII vesicle coat smooth endoplasmic reticulum membrane perinuclear region of cytoplasm	protein binding molecular_function protein binding zinc ion binding protein binding zinc ion binding