The LabelHash Server

Top 150 matches

For each match you can click on the "[pdb]" link to download a PDB file with the matching chain aligned with the motif.
Download a zip file with PDB files for all the matches and the motif itself.

PDB ID		LRMSD / p-value	Matching Residues	EC	Gene Ontology annotations
PDB ID		LRMSD / p-value	Matching Residues	EC	Biological Process	Cellular Component	Molecular Function
1k97A argininosuccinate synthase	[pdb]	0.155 1.98e-05	106^ARG 139^PHE 202^GLU 286^LYS 288^ARG 331^TYR	6.3.4.5	arginine biosynthetic process cellular amino acid biosynthetic process	cytoplasm	nucleotide binding argininosuccinate synthase activity protein binding ATP binding ligase activity
2nz2A argininosuccinate synthase	[pdb]	0.398 7.1e-05	95^ARG 128^PHE 191^GLU 277^LYS 279^ARG 322^TYR	6.3.4.5	urea cycle argininosuccinate metabolic process kidney development liver development arginine biosynthetic process acute-phase response response to nutrient cellular amino acid biosynthetic process response to biotic stimulus response to zinc ion response to lipopolysaccharide response to drug response to peptide hormone stimulus response to steroid hormone stimulus response to glucocorticoid stimulus	cytoplasm mitochondrial outer membrane endoplasmic reticulum	nucleotide binding argininosuccinate synthase activity protein binding ATP binding ligase activity
1kh1B argininosuccinate synthetase	[pdb]	0.449 9.01e-05	92^ARG 125^PHE 184^GLU 265^LYS 267^ARG 310^TYR	6.3.4.5	arginine biosynthetic process cellular amino acid biosynthetic process	cytoplasm	nucleotide binding argininosuccinate synthase activity ATP binding ligase activity
1vl2B argininosuccinate synthase	[pdb]	0.589 0.000141	93^ARG 126^PHE 189^GLU 275^LYS 277^ARG 320^TYR	6.3.4.5	arginine biosynthetic process cellular amino acid biosynthetic process	cytoplasm	nucleotide binding argininosuccinate synthase activity ATP binding ligase activity
1kobA twitchin	[pdb]	1.14 0.000192	69^ARG 79^PHE 134^GLU 186^LYS 138^ARG 26^TYR	0.0.0.0	protein phosphorylation		protein kinase activity protein serine/threonine kinase activity ATP binding
1m41B fmnh2-dependent alkanesulfonate monooxygenase	[pdb]	1.24 0.000236	1226^ARG 1326^PHE 1208^GLU 1220^LYS 1211^ARG 1174^TYR	1.14.14.5	alkanesulfonate catabolic process oxidation-reduction process		monooxygenase activity alkanesulfonate monooxygenase activity oxidoreductase activity
3gebC eyes absent homolog 2	[pdb]	1.31 0.000274	486^ARG 491^PHE 337^SER 388^LYS 385^ARG 473^TYR	0.0.0.0	DNA repair protein dephosphorylation apoptosis response to DNA damage stimulus multicellular organismal development mesodermal cell fate specification metabolic process chromatin modification histone dephosphorylation	nucleus cytoplasm	magnesium ion binding catalytic activity phosphoprotein phosphatase activity protein tyrosine phosphatase activity protein binding hydrolase activity metal ion binding
2b5wA glucose dehydrogenase	[pdb]	1.36 0.000314	88^ARG 113^PHE 22^GLU 18^LYS 20^ARG 123^TYR	0.0.0.0	metabolic process oxidation-reduction process		catalytic activity binding zinc ion binding oxidoreductase activity glucose 1-dehydrogenase activity
3nx2B ferulic acid decarboxylase	[pdb]	1.44 0.000378	142^ARG 140^PHE 64^SER 67^LYS 60^ARG 30^TYR				binding carboxy-lyase activity
1jilA tyrosyl-trna synthetase	[pdb]	1.46 0.000401	183^ARG 178^PHE 135^SER 142^LYS 138^ARG 211^TYR	0.0.0.0	translation tRNA aminoacylation for protein translation tyrosyl-tRNA aminoacylation	cytoplasm	nucleotide binding RNA binding aminoacyl-tRNA ligase activity tyrosine-tRNA ligase activity ATP binding ligase activity
2yy3A elongation factor 1-beta	[pdb]	1.47 0.000409	60^ARG 4^PHE 86^GLU 54^LYS 11^ARG 36^TYR	0.0.0.0	translation translational elongation	eukaryotic translation elongation factor 1 complex	translation elongation factor activity
1u69B hypothetical protein	[pdb]	1.59 0.000669	55^ARG 54^PHE 115^SER 111^LYS 109^ARG 22^TYR	0.0.0.0
2zjaA putative ski2-type helicase	[pdb]	1.6 0.000696	317^ARG 316^PHE 50^SER 202^LYS 199^ARG 374^TYR	0.0.0.0	DNA repair		nucleotide binding nucleic acid binding DNA binding helicase activity protein binding ATP binding ATP-dependent helicase activity hydrolase activity
2yx1A hypothetical protein mj0883	[pdb]	1.61 0.000754	136^ARG 134^PHE 87^GLU 82^LYS 85^ARG 97^TYR	0.0.0.0
1igoA family 11 xylanase	[pdb]	1.62 0.000821	49^ARG 48^PHE 145^SER 150^LYS 147^ARG 70^TYR	0.0.0.0	carbohydrate metabolic process metabolic process xylan catabolic process		hydrolase activity hydrolyzing O-glycosyl compounds hydrolase activity hydrolase activity
3emrA ectd	[pdb]	1.63 0.000821	131^ARG 104^PHE 268^SER 292^LYS 272^ARG 286^TYR	0.0.0.0	oxidation-reduction process		oxidoreductase activity
3mguA pkhd-type hydroxylase tpa1	[pdb]	1.63 0.000858	413^ARG 511^PHE 288^GLU 629^LYS 289^ARG 416^TYR	0.0.0.0	nuclear-transcribed mRNA catabolic process deadenylation-dependent decay translational termination	nucleus	iron ion binding protein binding poly(A) RNA binding oxidoreductase activity oxidoreductase activity acting on single donors with incorporation of molecular oxygen incorporation of two atoms of oxygen oxidoreductase activity acting on paired donors
2nqyB family 11 xylanase	[pdb]	1.63 0.000858	49^ARG 48^PHE 146^SER 151^LYS 148^ARG 70^TYR	0.0.0.0	carbohydrate metabolic process metabolic process xylan catabolic process		hydrolase activity hydrolyzing O-glycosyl compounds hydrolase activity hydrolase activity
2olsA phosphoenolpyruvate synthase	[pdb]	1.64 0.000897	650^ARG 648^PHE 740^SER 747^LYS 743^ARG 695^TYR	2.7.9.2	gluconeogenesis phosphorylation		nucleotide binding catalytic activity ATP binding pyruvate water dikinase activity kinase activity transferase activity transferase activity
1gl9C reverse gyrase	[pdb]	1.64 0.000897	848^ARG 802^PHE 781^SER 788^LYS 785^ARG 880^TYR	5.99.1.3	DNA metabolic process DNA topological change DNA unwinding involved in replication	chromosome	nucleotide binding nucleic acid binding DNA binding DNA topoisomerase activity DNA topoisomerase type I activity DNA topoisomerase (ATP-hydrolyzing) activity helicase activity ATP binding ATP-dependent helicase activity hydrolase activity isomerase activity metal ion binding
3hwcD chlorophenol-4-monooxygenase component 2	[pdb]	1.65 0.000938	283^ARG 285^PHE 344^GLU 84^LYS 80^ARG 107^TYR	0.0.0.0	metabolic process phenylacetate catabolic process oxidation-reduction process		acyl-CoA dehydrogenase activity monooxygenase activity oxidoreductase activity oxidoreductase activity acting on the CH-CH group of donors
1h4hD xylanase	[pdb]	1.65 0.000938	49^ARG 48^PHE 146^SER 151^LYS 148^ARG 70^TYR	0.0.0.0	carbohydrate metabolic process metabolic process xylan catabolic process		hydrolase activity hydrolyzing O-glycosyl compounds hydrolase activity hydrolase activity
3ck7D susd	[pdb]	1.65 0.000938	307^ARG 404^PHE 492^GLU 332^LYS 487^ARG 386^TYR	0.0.0.0
3icqC exportin-t gtp-binding nuclear protein gsp1/cnr1 rna (62-mer)	[pdb]	1.65 0.000982	31^ARG 37^PHE 96^SER 129^LYS 131^ARG 157^TYR	0.0.0.0	exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA 5.8S rRNA LSU-rRNA) transport intracellular protein transport nucleocytoplasmic transport nucleus organization signal transduction protein transport regulation of chromatin silencing at telomere protein targeting	nucleus cytoplasm nucleus nuclear envelope nuclear pore cytoplasm cytosol	nucleotide binding GTPase activity protein binding GTP binding tRNA binding RNA binding binding GTP binding
2on7D na glutathione s-transferase 1	[pdb]	1.67 0.00107	129^ARG 132^PHE 162^GLU 187^LYS 189^ARG 178^TYR	0.0.0.0
1wmiA hypothetical protein phs013 hypothetical protein phs014	[pdb]	1.67 0.00112	40^GLU 43^GLU 34^GLU 6^LYS 4^ARG 57^ILE	0.0.0.0
2qm3A predicted methyltransferase	[pdb]	1.68 0.00112	233^ARG 235^PHE 323^GLU 244^LYS 247^ARG 331^TYR	0.0.0.0
2b5dX alpha-amylase	[pdb]	1.68 0.00117	259^ARG 261^PHE 95^GLU 87^LYS 91^ARG 106^TYR
3ibgF atpase, subunit of the get complex	[pdb]	1.69 0.00117	81^ARG 76^PHE 153^GLU 52^LYS 54^ARG 86^TYR	0.0.0.0	transport cellular metal ion homeostasis	cytoplasm endoplasmic reticulum	nucleotide binding ATP binding hydrolase activity metal ion binding
2zgiC putative 4-amino-4-deoxychorismate lyase	[pdb]	1.7 0.00134	112^ARG 146^PHE 177^GLU 126^LYS 124^ARG 133^TYR	0.0.0.0	metabolic process		catalytic activity lyase activity
3nr9A dual specificity protein kinase clk2	[pdb]	1.71 0.00141	268^ARG 272^PHE 317^SER 255^LYS 316^ARG 375^TYR		protein phosphorylation	nucleus	nucleotide binding protein kinase activity protein serine/threonine kinase activity protein tyrosine kinase activity ATP binding kinase activity transferase activity
2c5eB gdp-mannose-3', 5'-epimerase	[pdb]	1.72 0.00147	197^ARG 138^PHE 41^SER 48^LYS 45^ARG 22^TYR	5.1.3.18	metabolic process L-ascorbic acid biosynthetic process cellular metabolic process		nucleotide binding catalytic activity binding isomerase activity GDP-mannose 3,5-epimerase activity coenzyme binding NAD binding
3bpbA dimethylarginine dimethylaminohydrolase	[pdb]	1.72 0.00147	253^ARG 2^PHE 234^GLU 224^LYS 222^ARG 169^TYR	0.0.0.0		cytoplasm	hydrolase activity
2eg3B probable thiosulfate sulfurtransferase	[pdb]	1.74 0.00161	212^ARG 201^PHE 43^GLU 35^LYS 37^ARG 190^TYR	0.0.0.0	sulfate transport		thiosulfate sulfurtransferase activity transferase activity
3nbyF snurportin-1 gtp-binding nuclear protein ran exportin-1	[pdb]	1.74 0.00168	29^ASP 35^LEU 94^LEU 127^ILE 129^LYS 155^GLY		spliceosomal snRNP assembly protein import into nucleus transport intracellular protein transport DNA metabolic process RNA export from nucleus protein export from nucleus transport intracellular protein transport nucleocytoplasmic transport cell cycle mitotic spindle organization mitosis signal transduction protein transport androgen receptor signaling pathway interspecies interaction between organisms positive regulation of transcription DNA-dependent cell division protein export from nucleus transport intracellular protein transport response to virus regulation of centrosome duplication protein transport protein localization to nucleus regulation of protein catabolic process regulation of protein export from nucleus	nucleus nuclear pore cytoplasm cytosol nucleus nuclear pore nucleoplasm cytoplasm cytosol melanosome chromatin kinetochore nucleus annulate lamellae nucleoplasm nucleolus cytoplasm Cajal body ribonucleoprotein complex	RNA cap binding RNA binding protein transporter activity nucleotide binding chromatin binding transcription coactivator activity GTPase activity protein binding GTP binding androgen receptor binding RNA binding binding protein binding protein transporter activity
2dckA xylanase j	[pdb]	1.75 0.00176	48^ARG 47^PHE 145^SER 150^LYS 147^ARG 69^TYR	0.0.0.0	carbohydrate metabolic process metabolic process xylan catabolic process		hydrolase activity hydrolyzing O-glycosyl compounds hydrolase activity hydrolase activity acting on glycosyl bonds
3hurA alanine racemase	[pdb]	1.75 0.00176	260^ARG 261^PHE 301^SER 307^LYS 308^ARG 328^TYR	0.0.0.0	alanine metabolic process peptidoglycan biosynthetic process		catalytic activity alanine racemase activity isomerase activity pyridoxal phosphate binding
3bm3A pspgi restriction endonuclease dna (5'-d(cpaptpcpcpapgpgptpapc)-3') dna (5'-d(gpgptpapcpcptpgpgpapt)-3')	[pdb]	1.75 0.00184	211^ARG 187^PHE 165^GLU 162^LYS 164^ARG 213^TYR		DNA restriction-modification system		DNA binding endonuclease activity Type II site-specific deoxyribonuclease activity
3ffhA histidinol-phosphate aminotransferase	[pdb]	1.75 0.00184	340^ARG 304^PHE 357^GLU 290^LYS 291^ARG 298^TYR	2.6.1.9	histidine biosynthetic process cellular amino acid biosynthetic process biosynthetic process		catalytic activity histidinol-phosphate transaminase activity transaminase activity transferase activity transferase activity transferring nitrogenous groups
1orrA cdp-tyvelose-2-epimerase	[pdb]	1.76 0.00184	199^ARG 201^PHE 123^SER 127^LYS 191^ARG 196^TYR	5.1.3.10	metabolic process lipopolysaccharide biosynthetic process cellular metabolic process		catalytic activity binding isomerase activity CDP-abequose epimerase activity coenzyme binding
3pnnA conserved domain protein	[pdb]	1.76 0.00184	42^ARG 129^PHE 291^GLU 285^LYS 287^ARG 35^TYR	0.0.0.0
3llkB sulfhydryl oxidase 1	[pdb]	1.76 0.00192	313^ARG 446^PHE 356^GLU 362^LYS 360^ARG 368^TYR	1.8.3.2	protein thiol-disulfide exchange cell redox homeostasis oxidation-reduction process	Golgi membrane extracellular region extracellular space Golgi apparatus membrane integral to membrane integral to Golgi membrane	oxidoreductase activity flavin-linked sulfhydryl oxidase activity thiol oxidase activity
1f5jA beta-1,4-xylanase	[pdb]	1.77 0.002	47^ARG 46^PHE 142^SER 147^LYS 144^ARG 66^TYR	0.0.0.0	carbohydrate metabolic process metabolic process xylan catabolic process		hydrolase activity hydrolyzing O-glycosyl compounds hydrolase activity hydrolase activity acting on glycosyl bonds
1f28C thymidylate synthase	[pdb]	1.77 0.002	56^ARG 58^PHE 43^SER 47^LYS 45^ARG 285^TYR	2.1.1.45	dTMP biosynthetic process nucleotide biosynthetic process		thymidylate synthase activity methyltransferase activity transferase activity
2on5H na glutathione s-transferase 2	[pdb]	1.77 0.002	129^ARG 132^PHE 162^GLU 187^LYS 189^ARG 175^TYR	0.0.0.0
1htyA alpha-mannosidase ii	[pdb]	1.77 0.00201	228^ARG 206^PHE 47^GLU 821^LYS 51^ARG 231^TYR	3.2.1.114	carbohydrate metabolic process mannose metabolic process metabolic process	Golgi membrane endoplasmic reticulum Golgi apparatus Golgi stack membrane integral to membrane	catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds alpha-mannosidase activity mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity zinc ion binding mannosidase activity hydrolase activity hydrolase activity acting on glycosyl bonds carbohydrate binding
1we5A putative family 31 glucosidase yici	[pdb]	1.77 0.00209	168^ARG 169^PHE 231^SER 227^LYS 153^ARG 163^TYR	0.0.0.0	carbohydrate metabolic process metabolic process		catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds protein binding hydrolase activity hydrolase activity
3fwlA penicillin-binding protein 1b	[pdb]	1.78 0.00209	286^ARG 277^PHE 233^GLU 303^LYS 235^ARG 292^TYR	2.4.1.129	cellular cell wall organization regulation of cell shape peptidoglycan biosynthetic process peptidoglycan-based cell wall biogenesis response to antibiotic	plasma membrane peptidoglycan-based cell wall membrane integral to membrane	catalytic activity protein binding drug binding peptidase activity penicillin binding peptidoglycan glycosyltransferase activity serine-type D-Ala-D-Ala carboxypeptidase activity transferase activity transferase activity transferring glycosyl groups
1gtmA glutamate dehydrogenase	[pdb]	1.78 0.00219	396^ARG 331^PHE 195^SER 203^LYS 199^ARG 385^TYR	1.4.1.3	cellular amino acid metabolic process metabolic process oxidation-reduction process	cytoplasm	catalytic activity glutamate dehydrogenase [NAD(P)+] activity binding oxidoreductase activity oxidoreductase activity
3hn3D beta-glucuronidase	[pdb]	1.78 0.00219	216^ARG 361^PHE 432^GLU 438^LYS 435^ARG 29^TYR	3.2.1.31	carbohydrate metabolic process glycosaminoglycan catabolic process metabolic process	soluble fraction lysosome microsome	catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds beta-glucuronidase activity sugar binding hydrolase activity hydrolase activity
3ikmA dna polymerase subunit gamma-1 dna polymerase subunit gamma-2	[pdb]	1.79 0.00229	802^ARG 800^PHE 593^SER 461^THR 579^ARG 452^LEU	2.7.7.7	DNA metabolic process DNA replication DNA-dependent DNA replication mitochondrial DNA replication base-excision repair gap-filling aging DNA replication DNA-dependent DNA replication DNA repair translation	mitochondrion mitochondrial inner membrane gamma DNA polymerase complex mitochondrial nucleoid mitochondrial chromosome cytoplasm mitochondrion mitochondrial nucleoid	protease binding nucleic acid binding DNA binding DNA-directed DNA polymerase activity exonuclease activity protein binding transferase activity nucleotidyltransferase activity nucleotide binding DNA binding single-stranded DNA binding DNA-directed DNA polymerase activity aminoacyl-tRNA ligase activity glycine-tRNA ligase activity protein binding ATP binding transferase activity nucleotidyltransferase activity identical protein binding
2v6eB protelemorase telrl	[pdb]	1.79 0.00229	492^ARG 496^PHE 479^GLU 453^LYS 447^ARG 504^TYR	0.0.0.0
2ws2B glutathione s-transferase	[pdb]	1.8 0.00239	129^ARG 132^PHE 162^GLU 185^LYS 187^ARG 173^TYR	0.0.0.0			transferase activity
2vlaA 5'-d(tpcpcpapcpgpgpgptpap cpc)-3' 5'-d(gpgptpapcpcpcpgptpgp gpa)-3' restriction endonuclease r.bpuji	[pdb]	1.81 0.00249	136^ARG 115^PHE 218^GLU 157^LYS 224^ARG 140^TYR	0.0.0.0			endonuclease activity
1vpqA hypothetical protein tm1631	[pdb]	1.81 0.00249	191^ARG 238^PHE 226^GLU 232^LYS 230^ARG 189^TYR	0.0.0.0
2gx5C gtp-sensing transcriptional pleiotropicrepressor cody	[pdb]	1.81 0.00249	103^ARG 106^PHE 67^GLU 47^LYS 69^ARG 75^TYR	0.0.0.0		cytoplasm	nucleotide binding DNA binding GTP binding transcription repressor activity
2pk3B gdp-6-deoxy-d-lyxo-4-hexulose reductase	[pdb]	1.81 0.00249	108^ARG 67^PHE 130^GLU 284^LYS 282^ARG 227^TYR	0.0.0.0	metabolic process cellular metabolic process		catalytic activity binding coenzyme binding
1gvhA flavohemoprotein	[pdb]	1.81 0.00249	184^ARG 253^PHE 150^GLU 244^LYS 153^ARG 217^TYR	1.14.12.17	transport response to toxin oxygen transport oxidation-reduction process	cytoplasm	oxygen transporter activity iron ion binding nitric oxide dioxygenase activity oxidoreductase activity oxygen binding heme binding metal ion binding
1zavA 50s ribosomal protein l7/l12 50s ribosomal protein l10	[pdb]	1.81 0.0026	112^ARG 26^GLU 39^HOH 47^HOH 43^HOH 100^HOH	0.0.0.0	translation ribosome biogenesis translation	intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex	structural constituent of ribosome structural constituent of ribosome
1up6E 6-phospho-beta-glucosidase	[pdb]	1.81 0.0026	80^ARG 79^PHE 147^GLU 157^LYS 150^ARG 123^TYR	3.2.1.86	carbohydrate metabolic process metabolic process		catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds binding 6-phospho-beta-glucosidase activity hydrolase activity hydrolase activity
2cagA catalase compound ii	[pdb]	1.81 0.0026	299^ARG 61^PHE 239^SER 56^LYS 237^ARG 304^TYR	1.11.1.6	response to oxidative stress hydrogen peroxide catabolic process oxidation-reduction process	cytoplasm	catalase activity peroxidase activity iron ion binding oxidoreductase activity heme binding metal ion binding
2zkrm rna expansion segment es15 part i e site t-rna rna expansion segment es27 rna expansion segment es9 rna expansion segment es20 60s ribosomal protein l10a rna expansion segment es3 60s ribosomal protein l10 rna helices 60s ribosomal protein l12 60s acidic ribosomal protein p0 rna expansion segment es9 part2 60s ribosomal protein l30e 60s ribosomal protein l17 60s ribosomal protein l32 60s ribosomal protein l19 rna expansion segment es31 part ii 60s ribosomal protein l31 rna expansion segment es39 part i 60s ribosomal protein l35 rna expansion segment es39 part ii 60s ribosomal protein l4 rna expansion segment es41 rna expansion segment es7 part iii rna expansion segment es24 60s ribosomal protein l11 rna expansion segment es30 60s ribosomal protein l15e 60s ribosomal protein l44e 5.8s ribosomal rna rna expansion segment es7 part ii 60s ribosomal protein l8 60s ribosomal protein l37e 60s ribosomal protein l13a 60s ribosomal protein l3 60s ribosomal protein l7 60s ribosomal protein l27a 60s ribosomal protein l5 60s ribosomal protein l23a 5s ribosomal rna rna expansion segment es4 60s ribosomal protein l39e 60s ribosomal protein l21 rna expansion segment es5 60s ribosomal protein l23 60s ribosomal protein l37a 60s ribosomal protein l24 60s ribosomal protein l26 rna expansion segment es7 part i 60s ribosomal protein l18 60s ribosomal protein l9 rna expansion segment es12 rna expansion segment es15 part ii rna expansion segment es10 60s ribosomal protein l7a rna expansion segment es39 part iii 28s ribosomal rna rna expansion segment es31 part i rna expansion segment es19	[pdb]	1.82 0.00272	63^TYR 129^PRO 160^HIS 170^ALA 169^SER 119^GLY	0.0.0.0	translation translation translation RNA processing translation translation translation translation translation translation translation translation translation ribosomal large subunit assembly translation exit from mitosis optic nerve development retinal ganglion cell axon guidance mitotic cell cycle G1/S transition checkpoint retina development in camera-type eye ribosome biogenesis translation translation translational elongation translation translation translation	intracellular ribosome ribonucleoprotein complex intracellular ribosome large ribosomal subunit ribonucleoprotein complex intracellular ribosome intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome intracellular ribosome intracellular ribosome ribonucleoprotein complex intracellular nucleolus ribosome ribonucleoprotein complex ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome intracellular ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome intracellular ribosome intracellular ribosome ribonucleoprotein complex intracellular ribosome intracellular ribosome ribonucleoprotein complex	structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome RNA binding structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome protein binding 5S rRNA binding structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome nucleotide binding RNA binding structural constituent of ribosome structural constituent of ribosome protein binding structural constituent of ribosome protein binding structural constituent of ribosome structural constituent of ribosome rRNA binding structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome protein binding
3a8tA adenylate isopentenyltransferase	[pdb]	1.82 0.00272	235^ARG 234^PHE 210^GLU 220^LYS 215^ARG 201^TYR	0.0.0.0	tRNA processing cytokinin biosynthetic process isopentenyl adenine biosynthetic process		nucleotide binding ATP binding AMP dimethylallyltransferase activity transferase activity
3olmA ubiquitin e3 ubiquitin-protein ligase rsp5	[pdb]	1.82 0.00272	550^ARG 545^PHE 502^GLU 462^LYS 461^ARG 469^TYR		DNA repair response to DNA damage stimulus ribosomal large subunit export from nucleus protein polyubiquitination chromatin assembly or disassembly rRNA processing tRNA export from nucleus protein modification process ubiquitin-dependent protein catabolic process protein monoubiquitination regulation of nitrogen utilization mitochondrion organization tRNA processing positive regulation of gene-specific transcription from RNA polymerase II promoter regulation of mRNA export from nucleus regulation of dolichol biosynthetic process regulation of ubiquinone biosynthetic process regulation of multivesicular body size regulation of phosphate metabolic process regulation of ergosterol biosynthetic process late endosome to vacuole transport via multivesicular body sorting pathway regulation of protein localization regulation of actin cytoskeleton organization ribophagy cellular response to UV response to drug protein ubiquitination involved in ubiquitin-dependent protein catabolic process proteasomal ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway positive regulation of fatty acid biosynthetic process positive regulation of endocytosis positive regulation of receptor-mediated endocytosis ubiquitin-dependent endocytosis	nucleus cytoplasm ubiquitin ligase complex plasma membrane enriched fraction intracellular nucleus cytoplasm mitochondrion Golgi apparatus cellular bud tip endosome membrane extrinsic to internal side of plasma membrane	ubiquitin-protein ligase activity protein binding ligase activity acid-amino acid ligase activity phosphatidylinositol binding identical protein binding ubiquitin binding
1vdyA hypothetical protein (rafl09-17-b18)	[pdb]	1.82 0.00284	85^ARG 129^PHE 52^GLU 66^LYS 57^ARG 75^TYR	0.0.0.0	intracellular protein transport	membrane	binding protein binding
1wcuA non-catalytic protein 1	[pdb]	1.83 0.00284	132^ARG 101^PHE 49^SER 77^LYS 116^ARG 65^TYR	0.0.0.0	carbohydrate metabolic process		hydrolase activity
2hqsG peptidoglycan-associated lipoprotein protein tolb	[pdb]	1.83 0.00284	81^ARG 84^PHE 160^GLU 150^LYS 112^ARG 78^TYR	0.0.0.0	transport protein transport protein import bacteriocin transport	outer membrane-bounded periplasmic space periplasmic space plasma membrane cell outer membrane membrane integral to membrane	protein binding protein binding
3i32A heat resistant rna dependent atpase	[pdb]	1.83 0.00296	325^ARG 244^PHE 354^GLU 362^LYS 360^ARG 213^TYR	0.0.0.0			nucleotide binding nucleic acid binding helicase activity ATP binding ATP-dependent helicase activity hydrolase activity
2e40B beta-glucosidase	[pdb]	1.84 0.00309	77^ARG 118^PHE 450^GLU 457^LYS 454^ARG 412^TYR	0.0.0.0	polysaccharide catabolic process carbohydrate metabolic process metabolic process cellulose catabolic process		catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds beta-glucosidase activity hydrolase activity hydrolase activity
1vcnA ctp synthetase	[pdb]	1.84 0.00309	172^ARG 173^PHE 131^GLU 138^LYS 135^ARG 14^TYR	6.3.4.2	pyrimidine nucleotide biosynthetic process glutamine metabolic process		nucleotide binding catalytic activity CTP synthase activity ATP binding ligase activity
2apcA alpha-1,3-mannosyl-glycoprotein 2-beta-n-acetylglucosaminyltransferase	[pdb]	1.84 0.00309	303^ARG 266^PHE 445^SER 397^LYS 393^ARG 418^TYR	2.4.1.101	protein N-linked glycosylation	Golgi membrane Golgi apparatus membrane integral to membrane	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity transferase activity transferase activity
1kruA galactoside o-acetyltransferase	[pdb]	1.84 0.00309	8^ARG 15^PHE 24^GLU 30^LYS 28^ARG 94^TYR	2.3.1.18	lactose biosynthetic process	cytoplasm	acyltransferase activity galactoside O-acetyltransferase activity transferase activity
2owmB related to kinesin-like protein kif1c	[pdb]	1.84 0.00309	202^ARG 194^PHE 370^SER 377^LYS 368^ARG 228^TYR		microtubule-based movement	microtubule	nucleotide binding motor activity microtubule motor activity ATP binding
3fqgA protein din1	[pdb]	1.84 0.00309	271^ARG 290^PHE 285^GLU 245^LYS 277^ARG 260^TYR	0.0.0.0	transcription termination DNA-dependent rRNA processing	nucleus cytosol
3is1X uro-adherence factor a	[pdb]	1.85 0.00322	607^ARG 606^PHE 665^SER 579^LYS 581^ARG 598^TYR	0.0.0.0	cell adhesion pathogenesis	extracellular region cell wall membrane	protein binding
2ib5E chromo protein	[pdb]	1.85 0.00322	179^ARG 88^PHE 145^GLU 71^LYS 220^ARG 79^TYR	0.0.0.0	bioluminescence protein-chromophore linkage
1uchA ubiquitin c-terminal hydrolase uch-l3	[pdb]	1.86 0.0035	221^ARG 222^PHE 92^SER 187^LYS 186^ARG 62^TYR	3.4.19.12	ubiquitin-dependent protein catabolic process	intracellular cytoplasm	ubiquitin thiolesterase activity protein binding peptidase activity cysteine-type peptidase activity hydrolase activity ubiquitin binding
3aqcD component b of hexaprenyl diphosphate synthase component a of hexaprenyl diphosphate synthase	[pdb]	1.86 0.0035	118^ARG 114^PHE 178^SER 45^LYS 48^ARG 22^TYR	0.0.0.0	isoprenoid biosynthetic process		transferase activity
3d3aA beta-galactosidase	[pdb]	1.87 0.00365	443^ARG 316^PHE 567^GLU 271^LYS 613^ARG 618^TYR	0.0.0.0	carbohydrate metabolic process cell adhesion		catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds
2gahD heterotetrameric sarcosine oxidase gamma-subunit heterotetrameric sarcosine oxidase delta-subunit heterotetrameric sarcosine oxidase beta-subunit heterotetrameric sarcosine oxidase alpha-subunit	[pdb]	1.88 0.00381	71^ARG 53^PHE 16^GLU 65^LYS 64^ARG 82^TYR	0.0.0.0	tetrahydrofolate metabolic process tetrahydrofolate metabolic process glycine catabolic process tetrahydrofolate metabolic process	cytoplasm	sarcosine oxidase activity oxidoreductase activity sarcosine oxidase activity aminomethyltransferase activity sarcosine oxidase activity
3ad7D subunit beta of sarcosine oxidase subunit alpha of sarocosine oxidase subunit gamma of sarcosine oxidase subunit delta of sarcosine oxidase	[pdb]	1.88 0.00381	71^ARG 53^PHE 16^GLU 65^LYS 64^ARG 82^TYR	0.0.0.0	glycine catabolic process metabolic process tetrahydrofolate metabolic process tetrahydrofolate metabolic process tetrahydrofolate metabolic process oxidation-reduction process	cytoplasm	catalytic activity aminomethyltransferase activity binding sarcosine oxidase activity sarcosine oxidase activity sarcosine oxidase activity oxidoreductase activity
1j0jB neopullulanase	[pdb]	1.88 0.00381	26^ARG 14^PHE 507^GLU 133^LYS 505^ARG 18^TYR	3.2.1.135	carbohydrate metabolic process metabolic process		catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds hydrolase activity hydrolase activity acting on glycosyl bonds neopullulanase activity
1i84S smooth muscle myosin essential light chain smooth muscle myosin heavy chain smooth muscle myosin regulatory light chain	[pdb]	1.88 0.00397	777^ARG 721^PHE 729^GLU 750^LYS 731^ARG 767^TYR	0.0.0.0	smooth muscle contraction skeletal muscle myosin thick filament assembly elastic fiber assembly cardiac muscle fiber development	cytosol myosin complex cytoplasm myosin complex myofibril myosin filament myosin complex	motor activity calcium ion binding structural constituent of muscle actin-dependent ATPase activity nucleotide binding motor activity actin binding calmodulin binding ATP binding structural constituent of muscle motor activity calcium ion binding
2q6tD dnab replication fork helicase	[pdb]	1.88 0.00397	208^ARG 394^PHE 384^SER 346^LYS 343^ARG 318^TYR		DNA replication		DNA binding DNA helicase activity helicase activity ATP binding
1ndgB antibody kappa light chain immunoglobulin gamma 1 chain lysozyme c	[pdb]	1.88 0.00397	338^ARG 340^PHE 383^SER 364^LYS 366^ARG 347^TYR	0.0.0.0	metabolic process cell wall macromolecule catabolic process cytolysis defense response to bacterium	extracellular region extracellular space plasma membrane membrane integral to membrane	lysozyme activity catalytic activity protein binding hydrolase activity hydrolase activity acting on glycosyl bonds antigen binding protein binding
3eh1A protein transport protein sec24b	[pdb]	1.89 0.00397	1211^ARG 1213^PHE 1156^GLU 1152^LYS 1155^ARG 1168^TYR	0.0.0.0	transport intracellular protein transport ER to Golgi vesicle-mediated transport protein transport cellular membrane organization vesicle-mediated transport	Golgi membrane cytoplasm endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus membrane COPII vesicle coat perinuclear region of cytoplasm	transporter activity protein binding zinc ion binding
2a52D gfp-like non-fluorescent chromoprotein fp595chain 2 gfp-like non-fluorescent chromoprotein fp595chain 1	[pdb]	1.89 0.00397	179^ARG 88^PHE 145^GLU 71^LYS 220^ARG 79^TYR	0.0.0.0	bioluminescence protein-chromophore linkage
3lgaC sam-dependent methyltransferase	[pdb]	1.89 0.00414	60^ARG 44^PHE 23^SER 35^LYS 25^ARG 18^TYR	0.0.0.0	tRNA methylation		methyltransferase activity tRNA (adenine-N1-)-methyltransferase activity transferase activity
2nraC 5'-d(gpapcpgptpapcptpapapgpcptpcptpcpaptpgp tptpcpt)-3' pi protein 5'-d(gpapapcpaptpgpapgpapgpcptptpapgptpapcp gptpcpt)-3'	[pdb]	1.89 0.00414	16^ARG 155^PHE 50^GLU 136^LYS 53^ARG 37^TYR	0.0.0.0	DNA replication DNA-dependent DNA replication initiation	extrachromosomal circular DNA	DNA-directed DNA polymerase activity
2ztjA homocitrate synthase	[pdb]	1.89 0.00414	240^ARG 237^PHE 286^SER 314^LYS 315^ARG 306^TYR	2.3.3.14	metabolic process cellular amino acid biosynthetic process lysine biosynthetic process carboxylic acid metabolic process	cytoplasm	catalytic activity homocitrate synthase activity transferase activity transferase activity
2j4oA mitogen-activated protein kinase kinase kinase7-interacting protein 1	[pdb]	1.9 0.00431	104^ARG 110^PHE 58^SER 55^LYS 57^ARG 179^TYR	0.0.0.0	activation of MAPKKK activity in utero embryonic development heart morphogenesis transforming growth factor beta receptor signaling pathway lung development	endosome membrane	catalytic activity protein binding enzyme activator activity kinase activator activity
3cfaH gfp-like fluorescent protein	[pdb]	1.9 0.00431	179^ARG 88^PHE 145^GLU 71^LYS 219^ARG 79^TYR	0.0.0.0	bioluminescence protein-chromophore linkage
3eb7B insecticidal delta-endotoxin cry8ea1	[pdb]	1.9 0.00431	269^ARG 270^PHE 331^SER 337^LYS 335^ARG 306^TYR	0.0.0.0	defense response pathogenesis sporulation resulting in formation of a cellular spore		receptor binding
3cb8A pyruvate formate-lyase 1-activating enzyme peptide substrate vsgyav	[pdb]	1.9 0.00431	148^ARG 108^PHE 185^GLU 195^LYS 188^ARG 155^TYR		carbohydrate metabolic process glucose metabolic process oxygen and reactive oxygen species metabolic process oxidation-reduction process	cytoplasm	catalytic activity oxidoreductase activity [formate-C-acetyltransferase]-activating enzyme activity metal ion binding iron-sulfur cluster binding 4 iron
2veaA phytochrome-like protein cph1	[pdb]	1.9 0.00431	310^ARG 308^PHE 272^SER 191^LYS 172^ARG 157^TYR	2.7.13.3	regulation of transcription DNA-dependent signal transduction sensory perception red far-red light phototransduction response to red or far red light peptidyl-histidine phosphorylation protein-chromophore linkage	membrane	two-component sensor activity nucleotide binding protein histidine kinase activity signal transducer activity receptor activity protein binding ATP binding G-protein coupled photoreceptor activity photoreceptor activity red or far-red light photoreceptor activity kinase activity transferase activity identical protein binding
3ib3A coce/nond family hydrolase	[pdb]	1.9 0.00431	276^ARG 279^PHE 493^GLU 477^LYS 462^ARG 199^TYR	0.0.0.0	metabolic process		dipeptidyl-peptidase activity hydrolase activity
3fvyA dipeptidyl-peptidase 3	[pdb]	1.9 0.00431	577^ARG 573^PHE 619^GLU 629^LYS 623^ARG 641^TYR	3.4.14.4	proteolysis	cytoplasm	aminopeptidase activity peptidase activity metallopeptidase activity dipeptidyl-peptidase activity hydrolase activity metal ion binding
1g6iA class i alpha-1,2-mannosidase	[pdb]	1.9 0.00449	273^ARG 270^PHE 232^GLU 240^LYS 233^ARG 255^TYR	3.2.1.113	protein N-linked glycosylation metabolic process ER-associated protein catabolic process	endoplasmic reticulum endoplasmic reticulum membrane membrane integral to membrane	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity calcium ion binding protein binding hydrolase activity hydrolase activity
1sazA probable butyrate kinase 2	[pdb]	1.9 0.00449	214^ARG 210^PHE 258^GLU 271^LYS 262^ARG 250^TYR	2.7.2.7	metabolic process phosphorylation	intracellular cytoplasm	nucleotide binding ATP binding kinase activity transferase activity phosphotransferase activity carboxyl group as acceptor
1cgyA cyclomaltodextrin glucanotransferase	[pdb]	1.91 0.00449	24^ARG 21^PHE 142^SER 106^LYS 103^ARG 112^TYR	2.4.1.19	carbohydrate metabolic process	extracellular region	catalytic activity transferase activity transferase activity transferring glycosyl groups carbohydrate binding cation binding cyclomaltodextrin glucanotransferase activity
2egiC hypothetical protein aq_1494	[pdb]	1.91 0.00467	33^ARG 36^PHE 83^SER 120^LYS 84^ARG 44^TYR	0.0.0.0			hydrolase activity
3mt1B putative carboxynorspermidine decarboxylase protein	[pdb]	1.92 0.00467	119^ARG 159^PHE 105^GLU 110^LYS 106^ARG 77^TYR	0.0.0.0			catalytic activity lyase activity
2p5iA bh3822 protein	[pdb]	1.92 0.00468	53^ARG 17^PHE 112^GLU 45^LYS 172^ARG 35^TYR	0.0.0.0	protein modification process		catalytic activity
2bvmA toxin b	[pdb]	1.92 0.00486	173^ARG 459^PHE 155^GLU 535^LYS 158^ARG 168^TYR	0.0.0.0	pathogenesis
2ppqA homoserine kinase	[pdb]	1.92 0.00486	270^ARG 307^PHE 168^GLU 164^LYS 167^ARG 301^TYR	2.7.1.39	cellular amino acid biosynthetic process threonine biosynthetic process		nucleotide binding homoserine kinase activity ATP binding kinase activity transferase activity
1s1iE 60s ribosomal protein l16-a 60s ribosomal protein l7-a 60s ribosomal protein l10 60s ribosomal protein l11 60s ribosomal protein l12 60s ribosomal protein l32 60s ribosomal protein l37-a 60s ribosomal protein l31 60s ribosomal protein l35 60s ribosomal protein l5 60s ribosomal protein l21-a 60s ribosomal protein l4-b 5.8s/25s ribosomal rna 60s ribosomal protein l26-a 60s ribosomal protein l2 60s ribosomal protein l3 60s ribosomal protein l1 60s ribosomal protein l9-a 60s ribosomal protein l28 60s ribosomal protein l8-a 5s ribosomal rna 60s ribosomal protein l24-a 60s ribosomal protein l23 60s ribosomal protein l18 60s ribosomal protein l25 60s ribosomal protein l15-a 60s ribosomal protein l19 60s ribosomal protein l43 60s ribosomal protein l42 60s ribosomal protein l17-a	[pdb]	1.92 0.00486	158^ARG 180^ASN 216^THR 224^GLN 218^ASP 99^ASN	0.0.0.0	translation translation translation ribosomal large subunit assembly translation ribosomal large subunit assembly translation translation translation RNA processing translation translation translation translation translation translation translation translation ribosome biogenesis ribosomal large subunit assembly translation ribosomal large subunit assembly translation translational termination translation translation regulation of translational fidelity maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA 5.8S rRNA LSU-rRNA) translation ribosomal large subunit assembly translation translation response to antibiotic response to cycloheximide translation response to antibiotic response to cycloheximide translation regulation of translational fidelity ribosomal large subunit assembly translation translation translation ribosomal large subunit assembly translation	intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome large ribosomal subunit cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome large ribosomal subunit cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome large ribosomal subunit cytosolic large ribosomal subunit ribonucleoprotein complex cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex preribosome large subunit precursor intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular nucleus cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome large ribosomal subunit cytosolic large ribosomal subunit ribonucleoprotein complex intracellular cytoplasm ribosome cytosolic large ribosomal subunit	RNA binding structural constituent of ribosome structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding metal ion binding RNA binding structural constituent of ribosome rRNA binding structural constituent of ribosome protein binding structural constituent of ribosome RNA binding structural constituent of ribosome RNA binding structural constituent of ribosome structural constituent of ribosome RNA binding structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome RNA binding structural constituent of ribosome rRNA binding structural constituent of ribosome protein binding transcription regulator activity structural constituent of ribosome protein binding RNA binding structural constituent of ribosome structural constituent of ribosome protein binding structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome nucleotide binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome RNA binding structural constituent of ribosome rRNA binding structural constituent of ribosome RNA binding structural constituent of ribosome RNA binding structural constituent of ribosome 5S rRNA binding rRNA binding RNA binding structural constituent of ribosome structural constituent of ribosome metal ion binding
1a05A 3-isopropylmalate dehydrogenase	[pdb]	1.92 0.00486	145^ARG 157^PHE 195^GLU 190^LYS 198^ARG 140^TYR	1.1.1.85	cellular amino acid biosynthetic process branched chain family amino acid biosynthetic process leucine biosynthetic process oxidation-reduction process	cytoplasm	magnesium ion binding 3-isopropylmalate dehydrogenase activity oxidoreductase activity oxidoreductase activity acting on the CH-OH group of donors NAD or NADP as acceptor
3kflA methionyl-trna synthetase	[pdb]	1.92 0.00486	382^ARG 414^PHE 404^GLU 485^LYS 401^ARG 494^TYR	0.0.0.0	translation tRNA aminoacylation for protein translation methionyl-tRNA aminoacylation	cytoplasm	nucleotide binding aminoacyl-tRNA ligase activity methionine-tRNA ligase activity ATP binding ligase activity
1nezA beta-2-microglobulin h-2 class i histocompatibility antigen, tla(c)alpha chain t-cell surface glycoprotein cd8 alpha chain	[pdb]	1.92 0.00486	35^GLY 36^CYS 55^TYR 165^LYS 170^ARG 27^GLU	0.0.0.0	T cell mediated immunity cell surface receptor linked signaling pathway T cell activation cytotoxic T cell differentiation positive regulation of calcium-mediated signaling positive regulation of T cell mediated cytotoxicity response to molecule of bacterial origin antigen processing and presentation of peptide antigen via MHC class I antigen processing and presentation of exogenous protein antigen via MHC class Ib TAP-dependent immune response cellular defense response response to drug response to cadmium ion antigen processing and presentation of peptide antigen via MHC class I immune response	external side of plasma membrane cell surface membrane integral to membrane extracellular region extracellular space external side of plasma membrane MHC class I protein complex membrane integral to membrane MHC class I protein complex	protein binding protein homodimerization activity protein binding
1fepA ferric enterobactin receptor	[pdb]	1.92 0.00486	316^ARG 337^PHE 112^SER 197^LYS 43^ARG 260^TYR	0.0.0.0	transport ion transport iron ion transport siderophore transport	plasma membrane cell outer membrane membrane integral to membrane	receptor activity transporter activity iron ion binding siderophore transmembrane transporter activity
2remB disulfide oxidoreductase 8 residue peptide	[pdb]	1.92 0.00486	178^ARG 173^PHE 29^GLU 151^LYS 19^ARG 12^TYR		cell redox homeostasis	outer membrane-bounded periplasmic space	protein disulfide oxidoreductase activity
2r9qD 2'-deoxycytidine 5'-triphosphate deaminase synthetic peptide 1 synthetic peptide 2	[pdb]	1.92 0.00506	291^ARG 290^PHE 268^GLU 210^LYS 267^ARG 262^TYR	0.0.0.0
3q08B chlorite dismutase	[pdb]	1.93 0.00506	183^ARG 200^PHE 166^GLU 151^LYS 163^ARG 186^TYR	0.0.0.0
3gmiA upf0348 protein mj0951	[pdb]	1.93 0.00506	323^ARG 320^PHE 307^GLU 298^LYS 300^ARG 287^TYR	0.0.0.0	biosynthetic process		catalytic activity
2qhsA lipoyltransferase	[pdb]	1.93 0.00526	43^ARG 68^PHE 74^GLU 50^LYS 49^ARG 81^TYR	2.3.1.181	protein modification process lipoate biosynthetic process	cytoplasm	catalytic activity acyltransferase activity octanoyltransferase activity transferase activity lipoyl(octanoyl) transferase activity
2rgxA adenylate kinase	[pdb]	1.93 0.00526	85^ARG 83^PHE 51^GLU 154^LYS 55^ARG 165^TYR	2.7.4.3	nucleobase	cytoplasm	nucleotide binding adenylate kinase activity ATP binding kinase activity transferase activity phosphotransferase activity phosphate group as acceptor nucleotide kinase activity
3evdA rna-directed rna polymerase ns5	[pdb]	1.93 0.00526	226^ARG 231^PHE 67^GLU 61^LYS 63^ARG 221^TYR	2.7.7.48, 2.1.1.56, 3.4.21.91	transcription RNA-dependent viral reproduction RNA metabolic process viral infectious cycle viral genome replication evasion by virus of host immune response methylation	extracellular region membrane integral to membrane virion viral capsid viral envelope ribonucleoprotein complex host cell membrane host cell nucleus host cell endoplasmic reticulum host cell endoplasmic reticulum membrane virion part virion membrane	nucleotide binding nucleic acid binding RNA binding RNA helicase activity double-stranded RNA binding catalytic activity RNA-directed RNA polymerase activity serine-type endopeptidase activity helicase activity mRNA (guanine-N7-)-methyltransferase activity mRNA (nucleoside-2'-O-)-methyltransferase activity structural molecule activity ATP binding methyltransferase activity peptidase activity serine-type peptidase activity transferase activity nucleotidyltransferase activity hydrolase activity nucleoside-triphosphatase activity metal ion binding
1smqC ribonucleoside-diphosphate reductase small chain1	[pdb]	1.94 0.00526	337^ARG 342^PHE 307^GLU 47^LYS 309^ARG 348^TYR	1.17.4.1	DNA replication deoxyribonucleoside diphosphate metabolic process deoxyribonucleotide biosynthetic process oxidation-reduction process	nucleus cytoplasm ribonucleoside-diphosphate reductase complex	ribonucleoside-diphosphate reductase activity protein binding oxidoreductase activity identical protein binding metal ion binding transition metal ion binding
1ni7A hypothetical protein ygdk	[pdb]	1.94 0.00526	122^ARG 116^PHE 83^SER 42^LYS 86^ARG 34^TYR	0.0.0.0			protein binding
1w63V adapter-related protein complex 1 gamma 1subunit adapter-related protein complex 1 sigma 1asubunit adaptor-related protein complex 1, mu 1 subunit adapter-related protein complex 1 beta 1 subunit	[pdb]	1.94 0.00526	357^ARG 325^PHE 377^SER 373^LYS 421^ARG 293^TYR	0.0.0.0	transport intracellular protein transport endocytosis protein transport vesicle-mediated transport transport intracellular protein transport endocytosis protein transport vesicle-mediated transport clathrin coat assembly transport intracellular protein transport protein transport vesicle-mediated transport transport intracellular protein transport endocytosis protein transport vesicle-mediated transport	Golgi apparatus trans-Golgi network membrane membrane coat clathrin adaptor complex clathrin coated vesicle membrane cytoplasmic vesicle Golgi apparatus part perinuclear region of cytoplasm Golgi apparatus membrane membrane coat clathrin coat clathrin adaptor complex clathrin coated vesicle membrane cytoplasmic vesicle Golgi apparatus trans-Golgi network membrane clathrin adaptor complex clathrin coated vesicle membrane cytoplasmic vesicle Golgi apparatus trans-Golgi network coated pit membrane membrane coat AP-1 adaptor complex clathrin coat of trans-Golgi network vesicle clathrin adaptor complex cytoplasmic vesicle membrane cytoplasmic vesicle	binding protein binding protein transporter activity binding protein binding protein transporter activity clathrin binding protein binding protein binding protein transporter activity
2d4vB isocitrate dehydrogenase	[pdb]	1.94 0.00526	212^ARG 152^PHE 250^GLU 287^LYS 256^ARG 216^TYR	0.0.0.0	glyoxylate cycle tricarboxylic acid cycle oxidation-reduction process		magnesium ion binding isocitrate dehydrogenase (NADP+) activity oxidoreductase activity oxidoreductase activity acting on the CH-OH group of donors NAD or NADP as acceptor
1py3A ribonuclease	[pdb]	1.94 0.00547	71^ARG 57^PHE 43^GLU 48^LYS 45^ARG 81^TYR	0.0.0.0			RNA binding endoribonuclease activity ribonuclease activity hydrolase activity
1uyqA beta-glucosidase a	[pdb]	1.94 0.00547	413^ARG 414^PHE 63^GLU 69^LYS 66^ARG 432^TYR	3.2.1.21	polysaccharide catabolic process carbohydrate metabolic process metabolic process cellulose catabolic process		catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds beta-glucosidase activity hydrolase activity hydrolase activity
2oc3A tyrosine-protein phosphatase non-receptor type18	[pdb]	1.94 0.00547	271^ARG 91^PHE 230^SER 59^LYS 61^ARG 68^TYR	3.1.3.48	protein dephosphorylation dephosphorylation	nucleus cytoplasm	phosphoprotein phosphatase activity protein tyrosine phosphatase activity non-membrane spanning protein tyrosine phosphatase activity protein binding hydrolase activity phosphatase activity
2a1aB interferon-induced, double-stranded rna-activated protein kinase eukaryotic translation initiation factor 2 alphasubunit	[pdb]	1.94 0.00547	499^ARG 495^PHE 461^SER 449^LYS 447^ARG 454^TYR	2.7.11.1	translation protein phosphorylation virus-infected cell apoptosis negative regulation of cell proliferation response to virus endoplasmic reticulum unfolded protein response negative regulation of osteoblast proliferation interspecies interaction between organisms protein autophosphorylation translation translational initiation	intracellular cytoplasm ribosome eukaryotic translation initiation factor 2 complex multi-eIF complex	nucleotide binding RNA binding double-stranded RNA binding protein kinase activity protein serine/threonine kinase activity eukaryotic translation initiation factor 2alpha kinase activity protein binding ATP binding protein phosphatase type 2A regulator activity kinase activity transferase activity RNA binding translation initiation factor activity
3dlcA putative s-adenosyl-l-methionine-dependentmethyltransferase	[pdb]	1.94 0.00547	117^ARG 206^PHE 132^GLU 212^LYS 135^ARG 144^TYR	0.0.0.0	metabolic process		methyltransferase activity transferase activity
3abzC beta-glucosidase i	[pdb]	1.94 0.00547	113^ARG 115^PHE 162^SER 684^LYS 689^ARG 592^TYR		carbohydrate metabolic process metabolic process		hydrolase activity hydrolyzing O-glycosyl compounds beta-glucosidase activity hydrolase activity
2exkA beta-d-xylosidase	[pdb]	1.94 0.00547	384^ARG 12^PHE 393^GLU 473^LYS 464^ARG 412^TYR	0.0.0.0	carbohydrate metabolic process		hydrolase activity
1f76B dihydroorotate dehydrogenase	[pdb]	1.94 0.00547	7^ARG 323^PHE 35^GLU 41^LYS 39^ARG 2^TYR	1.3.3.1	'de novo' pyrimidine base biosynthetic process pyrimidine nucleotide biosynthetic process UMP biosynthetic process metabolic process oxidation-reduction process	plasma membrane membrane	catalytic activity dihydroorotate dehydrogenase activity dihydroorotate oxidase activity oxidoreductase activity
2fnaA conserved hypothetical protein	[pdb]	1.95 0.00569	284^ARG 280^PHE 314^GLU 303^LYS 309^ARG 327^TYR	0.0.0.0
2pnyA isopentenyl-diphosphate delta-isomerase 2	[pdb]	1.95 0.00569	64^ARG 59^PHE 184^GLU 192^LYS 185^ARG 173^TYR	5.3.3.2	steroid biosynthetic process cholesterol biosynthetic process isoprenoid biosynthetic process lipid biosynthetic process carotenoid biosynthetic process sterol biosynthetic process	peroxisome cytosol	isopentenyl-diphosphate delta-isomerase activity hydrolase activity isomerase activity metal ion binding
2xikA serine/threonine protein kinase 25	[pdb]	1.95 0.00569	135^ARG 194^PHE 71^SER 155^LYS 80^ARG 130^TYR	2.7.11.1	protein phosphorylation response to oxidative stress signal transduction	cytoplasm Golgi apparatus	nucleotide binding protein kinase activity protein serine/threonine kinase activity protein binding ATP binding kinase activity transferase activity identical protein binding metal ion binding
1uj4A ribose 5-phosphate isomerase	[pdb]	1.95 0.00569	213^ARG 118^PHE 40^GLU 51^LYS 44^ARG 19^TYR	5.3.1.6	pentose-phosphate shunt		ribose-5-phosphate isomerase activity isomerase activity
2r4hC membrane-associated guanylate kinase, ww and pdzdomain-containing protein 1	[pdb]	1.95 0.00569	33^ARG 17^PHE 24^GLU 61^LYS 23^ARG 30^TYR	0.0.0.0	protein complex assembly cell adhesion cell surface receptor linked signaling pathway	plasma membrane cell-cell junction tight junction membrane cell junction	nucleotide binding protein binding ATP binding protein C-terminus binding
3hw4D polymerase acidic protein	[pdb]	1.95 0.00592	168^ARG 148^PHE 77^GLU 142^LYS 116^ARG 161^TYR				RNA binding RNA-directed RNA polymerase activity
2d7rA polypeptide n-acetylgalactosaminyltransferase 10	[pdb]	1.96 0.00592	221^ARG 235^PHE 385^SER 391^LYS 388^ARG 335^TYR	2.4.1.41	protein O-linked glycosylation	Golgi membrane Golgi apparatus membrane integral to membrane	polypeptide N-acetylgalactosaminyltransferase activity sugar binding transferase activity transferase activity transferring glycosyl groups
1um0C chorismate synthase	[pdb]	1.96 0.00592	322^ARG 302^PHE 124^SER 97^LYS 119^ARG 93^TYR	4.2.3.5	cellular amino acid biosynthetic process aromatic amino acid family biosynthetic process		chorismate synthase activity lyase activity
1qz9A kynureninase	[pdb]	1.96 0.00615	375^ARG 347^PHE 397^GLU 402^LYS 401^ARG 353^TYR	3.7.1.3	tryptophan catabolic process metabolic process NAD biosynthetic process pyridine nucleotide biosynthetic process	cytoplasm	catalytic activity hydrolase activity pyridoxal phosphate binding kynureninase activity
2j7cA beta-glucosidase a	[pdb]	1.96 0.00615	413^ARG 414^PHE 22^GLU 62^LYS 60^ARG 418^TYR	3.2.1.21	polysaccharide catabolic process carbohydrate metabolic process metabolic process cellulose catabolic process		catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds beta-glucosidase activity hydrolase activity hydrolase activity
2hekB hypothetical protein	[pdb]	1.96 0.00615	213^ARG 215^PHE 55^SER 35^LYS 51^ARG 221^TYR	0.0.0.0			catalytic activity
2p0mA arachidonate 15-lipoxygenase	[pdb]	1.96 0.00615	243^ARG 275^PHE 351^SER 345^LYS 349^ARG 231^TYR	1.13.11.33	leukotriene metabolic process leukotriene biosynthetic process oxidation-reduction process	cytoplasm	iron ion binding lipoxygenase activity oxidoreductase activity oxidoreductase activity acting on single donors with incorporation of molecular oxygen incorporation of two atoms of oxygen
3amjD zinc peptidase active subunit zinc peptidase inactive subunit	[pdb]	1.96 0.00615	168^SER 170^ALA 106^ASP 320^ALA 109^PHE 175^MET
1ojjB endoglucanase i	[pdb]	1.96 0.00615	285^ARG 129^PHE 205^SER 264^LYS 254^ARG 287^TYR	3.2.1.4	polysaccharide catabolic process carbohydrate metabolic process metabolic process cellulose catabolic process	extracellular region	hydrolase activity hydrolyzing O-glycosyl compounds cellulase activity hydrolase activity
3cymA uncharacterized protein bad_0989	[pdb]	1.97 0.00615	115^ARG 117^PHE 108^GLU 210^LYS 209^ARG 200^TYR	0.0.0.0	nucleobase nucleoside	intracellular	nucleotide binding nucleic acid binding catalytic activity 3'-5' exonuclease activity
2z6bD tail-associated lysozyme baseplate structural protein gp27	[pdb]	1.97 0.00639	174^ARG 187^PHE 278^SER 373^LYS 289^ARG 156^TYR	0.0.0.0	metabolic process peptidoglycan catabolic process cell wall macromolecule catabolic process cytolysis defense response to bacterium	virion	protein binding lysozyme activity catalytic activity protein binding hydrolase activity hydrolase activity
1aa6A formate dehydrogenase h	[pdb]	1.97 0.00639	506^ARG 512^PHE 364^GLU 358^LYS 363^ARG 118^TYR	1.2.1.2	formate metabolic process oxidation-reduction process	formate dehydrogenase complex	binding formate dehydrogenase activity electron carrier activity oxidoreductase activity molybdenum ion binding metal ion binding iron-sulfur cluster binding 4 iron
2qogC phospholipase a2 cb2 phospholipase a2 cb1	[pdb]	1.97 0.00639	43^ARG 46^PHE 12^GLU 16^LYS 14^ARG 113^TYR	3.1.1.4	phospholipid metabolic process lipid catabolic process phospholipid metabolic process synaptic transmission pathogenesis lipid catabolic process	extracellular region extracellular region presynaptic membrane	phospholipase A2 activity calcium ion binding hydrolase activity metal ion binding phospholipase A2 activity calcium ion binding hydrolase activity metal ion binding
1i73A neutrophil collagenase three residue peptide inhibitor	[pdb]	1.97 0.00639	222^ARG 221^PHE 108^GLU 114^LYS 111^ARG 227^TYR	3.4.24.34	ossification proteolysis metabolic process collagen catabolic process	extracellular region proteinaceous extracellular matrix extracellular space extracellular matrix	metalloendopeptidase activity serine-type endopeptidase activity calcium ion binding peptidase activity metallopeptidase activity zinc ion binding hydrolase activity metal ion binding
3evzA methyltransferase	[pdb]	1.97 0.00639	237^ARG 73^PHE 216^GLU 185^LYS 217^ARG 158^TYR	0.0.0.0			methyltransferase activity
3fqdA 5'-3' exoribonuclease 2 protein din1	[pdb]	1.97 0.00639	194^LEU 759^PHE 216^SER 209^CYS 215^ARG 53^ASP	0.0.0.0	transcription termination DNA-dependent rRNA processing mRNA processing mitotic sister chromatid segregation nucleobase nucleoside nucleotide and nucleic acid metabolic process transcription termination	nucleus cytosol intracellular nucleus	nucleic acid binding nuclease activity exonuclease activity 5'-3' exoribonuclease activity hydrolase activity