The LabelHash Server

Top 150 matches

For each match you can click on the "[pdb]" link to download a PDB file with the matching chain aligned with the motif.
Download a zip file with PDB files for all the matches and the motif itself.

PDB ID		LRMSD / p-value	Matching Residues	EC	Gene Ontology annotations
PDB ID		LRMSD / p-value	Matching Residues	EC	Biological Process	Cellular Component	Molecular Function
1tpyA methoxy mycolic acid synthase 2	[pdb]	0.095 3.04e-05	17^ASP 72^GLY 74^GLY 75^TRP 76^GLY 200^PHE	0.0.0.0	lipid biosynthetic process Actinobacterium-type cell wall biogenesis mycolic acid biosynthetic process	plasma membrane	methyltransferase activity cyclopropane-fatty-acyl-phospholipid synthase activity transferase activity
1kpiA cyclopropane-fatty-acyl-phospholipid synthase 2	[pdb]	0.205 6.1e-05	25^ASP 80^GLY 82^GLY 83^TRP 84^GLY 215^PHE	2.1.1.79	response to hypoxia lipid biosynthetic process S-adenosylmethionine metabolic process modulation by symbiont of host innate immunity Actinobacterium-type cell wall biogenesis mycolic acid biosynthetic process mycolate cell wall layer assembly	cytoplasm cytosol plasma membrane	methyltransferase activity cyclopropane-fatty-acyl-phospholipid synthase activity transferase activity
1l1eB mycolic acid synthase	[pdb]	1.07 0.000121	17^ASP 72^GLY 74^GLY 75^TRP 76^GLY 200^PHE	0.0.0.0	lipid biosynthetic process pathogenesis active evasion of host immune response S-adenosylmethionine metabolic process modulation by symbiont of host innate immunity mycolic acid biosynthetic process	cytoplasm	methyltransferase activity cyclopropane-fatty-acyl-phospholipid synthase activity transferase activity
2hhgA hypothetical protein rpa3614	[pdb]	1.38 0.000275	27^ASP 95^GLY 119^GLY 123^TRP 121^GLY 88^PHE	0.0.0.0
2id3B putative transcriptional regulator	[pdb]	1.38 0.000285	72^ASP 63^GLY 64^GLY 59^TRP 60^GLY 130^PHE	0.0.0.0	regulation of transcription		DNA binding sequence-specific DNA binding transcription factor activity specific transcriptional repressor activity transcription regulator activity
3eztB histone deacetylase 8	[pdb]	1.41 0.000318	183^ASP 265^GLY 303^GLY 141^TRP 139^GLY 207^PHE	3.5.1.98	negative regulation of transcription from RNA polymerase II promoter chromatin assembly or disassembly chromatin modification histone deacetylation	histone deacetylase complex nuclear chromosome nucleus cytoplasm	histone deacetylase activity transcription factor binding hydrolase activity metal ion binding
2rdyA bh0842 protein	[pdb]	1.43 0.000355	621^ASP 689^GLY 629^GLY 626^TRP 682^GLY 638^PHE	0.0.0.0			catalytic activity
1n6fF tricorn protease	[pdb]	1.45 0.000397	966^ASP 1021^GLY 989^GLY 988^TRP 208^GLY 1011^PHE	0.0.0.0	proteolysis	cytoplasm	protein binding peptidase activity serine-type peptidase activity hydrolase activity
3n2tA putative oxidoreductase	[pdb]	1.48 0.000446	93^ASP 62^GLY 60^GLY 28^TRP 26^GLY 100^PHE	0.0.0.0	oxidation-reduction process		oxidoreductase activity
2yxvB blue copper oxidase cueo	[pdb]	1.48 0.000463	197^ASP 218^GLY 155^GLY 67^TRP 68^GLY 210^PHE	0.0.0.0	response to copper ion oxidation-reduction process	periplasmic space	copper ion binding oxidoreductase activity oxidoreductase activity oxidizing metal ions
3bgtA probable acetoacetate decarboxylase	[pdb]	1.53 0.000587	235^ASP 107^GLY 108^GLY 112^TRP 113^GLY 27^PHE	4.1.1.4			lyase activity carboxy-lyase activity acetoacetate decarboxylase activity
1pf3A blue copper oxidase cueo	[pdb]	1.55 0.000661	197^ASP 218^GLY 155^GLY 67^TRP 68^GLY 210^PHE	0.0.0.0	response to copper ion oxidation-reduction process	periplasmic space	copper ion binding oxidoreductase activity oxidoreductase activity oxidizing metal ions
2o1oA putative farnesyl pyrophosphate synthase	[pdb]	1.58 0.000811	95^ASP 223^GLY 101^GLY 102^TRP 76^GLY 161^PHE	0.0.0.0	isoprenoid biosynthetic process		transferase activity
3ha5A methoxy mycolic acid synthase 4	[pdb]	1.61 0.00092	29^ASP 81^GLY 83^GLY 84^TRP 85^GLY 209^PHE	0.0.0.0	lipid biosynthetic process Actinobacterium-type cell wall biogenesis mycolic acid biosynthetic process	cell wall plasma membrane	methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity cyclopropane-fatty-acyl-phospholipid synthase activity transferase activity
2oz3A mandelate racemase/muconate lactonizing enzyme	[pdb]	1.62 0.000958	20^ASP 127^GLY 293^GLY 294^TRP 296^GLY 353^PHE	0.0.0.0	metabolic process cellular amino acid catabolic process		catalytic activity
1kb0A quinohemoprotein alcohol dehydrogenase	[pdb]	1.62 0.000999	497^ASP 546^GLY 542^GLY 541^TRP 68^GLY 456^PHE	0.0.0.0	oxidation-reduction process	membrane outer membrane-bounded periplasmic space periplasmic space	iron ion binding calcium ion binding electron carrier activity oxidoreductase activity oxidoreductase activity acting on CH-OH group of donors heme binding
2nuuA ammonia channel nitrogen regulatory protein p-ii 2	[pdb]	1.64 0.00109	313^ASP 268^GLY 264^GLY 245^TRP 244^GLY 31^THR	0.0.0.0	regulation of nitrogen utilization transport carbon dioxide transport ammonium transport transmembrane transport	plasma membrane membrane integral to membrane	nucleotide binding protein binding enzyme regulator activity ammonium transmembrane transporter activity uniporter activity ammonia transmembrane transporter activity
1t3tA phosphoribosylformylglycinamidine synthase	[pdb]	1.65 0.00113	473^ASP 373^GLY 372^GLY 305^TRP 369^GLY 1094^PHE	6.3.5.3	purine nucleotide biosynthetic process 'de novo' IMP biosynthetic process glutamine metabolic process	cytoplasm	nucleotide binding catalytic activity phosphoribosylformylglycinamidine synthase activity ATP binding ligase activity
1kkcA manganese superoxide dismutase	[pdb]	1.66 0.00123	154^ASP 135^GLY 142^GLY 141^TRP 140^GLY 125^PHE	1.15.1.1	superoxide metabolic process oxidation-reduction process	mitochondrion mitochondrial matrix	superoxide dismutase activity oxidoreductase activity metal ion binding
3fawA reticulocyte binding protein	[pdb]	1.66 0.00123	863^ASP 859^GLY 832^GLY 833^TRP 805^GLY 961^PHE	0.0.0.0	carbohydrate metabolic process	cell wall cell surface membrane	catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds carbohydrate binding
3mjtB amphb	[pdb]	1.67 0.00129	375^ASP 366^GLY 145^GLY 144^TRP 147^GLY 352^PHE	0.0.0.0	metabolic process biosynthetic process		acyl carrier activity catalytic activity binding oxidoreductase activity transferase activity phosphopantetheine binding cofactor binding
2fheB protein (ggl-cys-gly) protein (glutathione s-transferase)	[pdb]	1.67 0.00129	35^ASP 11^GLY 204^GLY 205^TRP 211^GLY 41^PHE	2.5.1.18	metabolic process		glutathione transferase activity transferase activity
1jfrB lipase	[pdb]	1.68 0.00134	94^ASP 129^GLY 134^GLY 156^TRP 155^GLY 38^PHE	0.0.0.0			hydrolase activity
2qzsA glycogen synthase	[pdb]	1.68 0.0014	176^ASP 141^GLY 114^GLY 115^TRP 117^GLY 169^PHE	2.4.1.21	glycogen biosynthetic process biosynthetic process glucan biosynthetic process		protein binding starch synthase activity transferase activity transferase activity
2va1F uridylate kinase	[pdb]	1.69 0.00146	19^ASP 49^GLY 50^GLY 54^TRP 73^GLY 25^PHE	0.0.0.0	pyrimidine nucleotide biosynthetic process cellular amino acid biosynthetic process	cytoplasm	nucleotide binding ATP binding uridylate kinase activity kinase activity transferase activity UMP kinase activity
1rwiA serine/threonine-protein kinase pknd	[pdb]	1.69 0.00152	169^ASP 112^GLY 154^GLY 195^TRP 196^GLY 146^PHE	2.7.11.1	protein phosphorylation pathogenesis negative regulation of protein binding positive regulation of catalytic activity negative regulation of catalytic activity	cytosol plasma membrane integral to plasma membrane	nucleotide binding protein kinase activity protein serine/threonine kinase activity ATP binding kinase activity transferase activity manganese ion binding protein homodimerization activity
1kitA sialidase	[pdb]	1.72 0.00165	390^ASP 479^GLY 361^GLY 362^TRP 364^GLY 440^PHE	3.2.1.18	metabolic process metabolic process	extracellular region extracellular region	exo-alpha-sialidase activity hydrolase activity hydrolase activity acting on glycosyl bonds exo-alpha-sialidase activity hydrolase activity
3ibzA putative tellurium resistant like protein terd	[pdb]	1.72 0.00172	144^ASP 26^GLY 28^GLY 29^TRP 82^GLY 157^PHE	0.0.0.0	response to stress
3mktB multi antimicrobial extrusion protein (na(+)/drugantiporter) mate-like mdr efflux pump	[pdb]	1.73 0.0018	371^ASP 406^GLY 428^GLY 426^TRP 424^GLY 395^PHE	0.0.0.0	drug transmembrane transport transmembrane transport	membrane integral to membrane	drug transmembrane transporter activity antiporter activity
1a0eA xylose isomerase	[pdb]	1.73 0.0018	338^ASP 292^GLY 333^GLY 138^TRP 183^GLY 362^PHE	5.3.1.5	carbohydrate metabolic process pentose-phosphate shunt D-xylose metabolic process	cytoplasm	xylose isomerase activity isomerase activity metal ion binding
3k2wC betaine-aldehyde dehydrogenase	[pdb]	1.73 0.0018	436^ASP 258^GLY 417^GLY 459^TRP 458^GLY 410^PHE	0.0.0.0	metabolic process oxidation-reduction process		betaine-aldehyde dehydrogenase activity oxidoreductase activity
1eg1C endoglucanase i	[pdb]	1.73 0.00187	172^ASP 154^GLY 169^GLY 180^TRP 183^GLY 317^PHE	3.2.1.4	polysaccharide catabolic process carbohydrate metabolic process metabolic process cellulose catabolic process	extracellular region	hydrolase activity hydrolyzing O-glycosyl compounds cellulase activity hydrolase activity hydrolase activity
2dtnB undecaprenyl pyrophosphate synthase	[pdb]	1.74 0.00187	214^ASP 183^GLY 182^GLY 207^TRP 14^GLY 222^PHE	2.5.1.31	cellular cell wall organization cell cycle regulation of cell shape peptidoglycan biosynthetic process cell division		di-trans,poly-cis-decaprenylcistransferase activity transferase activity transferase activity
3mvdL regulator of chromosome condensation histone h2b 1.1 histone h4 histone h3.2 histone h2a dna (146-mer)	[pdb]	1.74 0.00187	173^ASP 161^GLY 151^GLY 150^TRP 104^GLY 200^PHE	0.0.0.0	nucleosome assembly cell cycle mitosis regulation of mitotic cell cycle central nervous system development regulation of nucleocytoplasmic transport regulation of neurogenesis cell division nucleosome assembly nucleosome assembly nucleosome assembly	nucleosome nucleus chromosome nucleus cytoplasm nucleosome nucleus chromosome nucleosome nucleus chromosome nucleosome nucleus chromosome	DNA binding chromatin binding guanyl-nucleotide exchange factor activity protein binding DNA binding DNA binding DNA binding
1o7dA lysosomal alpha-mannosidase	[pdb]	1.75 0.00203	159^ASP 153^GLY 154^GLY 155^TRP 175^GLY 218^PHE	3.2.1.24	carbohydrate metabolic process mannose metabolic process protein modification process learning or memory metabolic process	lysosome	catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds alpha-mannosidase activity zinc ion binding mannosidase activity hydrolase activity hydrolase activity acting on glycosyl bonds carbohydrate binding
2e8zB amyx protein	[pdb]	1.76 0.00211	465^ASP 461^GLY 436^GLY 437^TRP 409^GLY 564^PHE	0.0.0.0	carbohydrate metabolic process metabolic process		catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds hydrolase activity hydrolase activity acting on glycosyl bonds
2kxvA tellurite resistance protein	[pdb]	1.76 0.00211	126^ASP 8^GLY 10^GLY 11^TRP 66^GLY 139^PHE		response to stress
2y5eA limit dextrinase	[pdb]	1.76 0.00211	541^ASP 537^GLY 511^GLY 512^TRP 476^GLY 682^PHE	0.0.0.0	carbohydrate metabolic process		catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds cation binding
1ub2A catalase-peroxidase	[pdb]	1.78 0.00238	123^ASP 282^GLY 291^GLY 292^TRP 277^GLY 115^PHE	1.11.1.7, 1.11.1.6	response to oxidative stress hydrogen peroxide catabolic process oxidation-reduction process		catalase activity peroxidase activity oxidoreductase activity heme binding metal ion binding
1ua7A alpha-amylase	[pdb]	1.78 0.00238	269^ASP 310^GLY 311^GLY 280^TRP 313^GLY 303^PHE	3.2.1.1	carbohydrate metabolic process metabolic process	extracellular region	catalytic activity alpha-amylase activity hydrolase activity hydrolase activity acting on glycosyl bonds cation binding
1wueA mandelate racemase/muconate lactonizing enzymefamily protein	[pdb]	1.78 0.00238	1239^ASP 1269^GLY 1268^GLY 1098^TRP 1100^GLY 1279^PHE	0.0.0.0	metabolic process		catalytic activity metal ion binding
3gpdR d-glyceraldehyde-3-phosphate dehydrogenase	[pdb]	1.78 0.00238	34^ASP 113^GLY 114^GLY 86^TRP 87^GLY 101^PHE	1.2.1.12	glucose metabolic process glycolysis metabolic process oxidation-reduction process	cytoplasm membrane perinuclear region of cytoplasm	catalytic activity glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity binding protein binding glyceraldehyde-3-phosphate dehydrogenase activity oxidoreductase activity NAD binding
2d5jA unsaturated glucuronyl hydrolase	[pdb]	1.78 0.00238	41^ASP 90^GLY 45^GLY 47^TRP 49^GLY 81^PHE	0.0.0.0	polysaccharide catabolic process carbohydrate metabolic process metabolic process	cytoplasm	catalytic activity hydrolase activity hydrolase activity
3dc5A superoxide dismutase [mn] 2	[pdb]	1.79 0.00247	112^ASP 153^GLY 123^GLY 122^TRP 121^GLY 100^PHE	1.15.1.1	nematode larval development superoxide metabolic process determination of adult lifespan growth axon extension oxidation-reduction process	mitochondrion mitochondrial matrix	superoxide dismutase activity oxidoreductase activity metal ion binding
2ps2C putative mandelate racemase/muconate lactonizingenzyme	[pdb]	1.79 0.00247	302^ASP 275^GLY 51^GLY 50^TRP 49^GLY 56^PHE	0.0.0.0	metabolic process		catalytic activity
3qnkB putative liporotein	[pdb]	1.79 0.00247	374^ASP 299^GLY 296^GLY 295^TRP 297^GLY 499^PHE
2fr1A erythromycin synthase, eryai	[pdb]	1.8 0.00257	1821^ASP 1812^GLY 1594^GLY 1593^TRP 1596^GLY 1798^PHE	2.3.1.94	metabolic process biosynthetic process antibiotic biosynthetic process		acyl carrier activity catalytic activity binding acyltransferase activity transferase activity phosphopantetheine binding erythronolide synthase activity cofactor binding
1u79A fkbp-type peptidyl-prolyl cis-trans isomerase 3	[pdb]	1.8 0.00257	122^ASP 76^GLY 73^GLY 70^TRP 62^GLY 7^PHE	5.2.1.8	protein folding	chloroplast plastid chloroplast thylakoid lumen thylakoid thylakoid lumen	peptidyl-prolyl cis-trans isomerase activity protein binding isomerase activity
1o9bB hypothetical shikimate 5-dehydrogenase-likeprotein ydib	[pdb]	1.8 0.00267	254^ASP 108^GLY 110^GLY 261^TRP 263^GLY 120^PHE	1.1.1.282	metabolic process cellular amino acid biosynthetic process aromatic amino acid family biosynthetic process oxidation-reduction process metabolic process cellular amino acid biosynthetic process aromatic amino acid family biosynthetic process oxidation-reduction process	cytoplasm cytoplasm	catalytic activity shikimate 5-dehydrogenase activity binding oxidoreductase activity quinate/shikimate dehydrogenase activity catalytic activity shikimate 5-dehydrogenase activity binding protein binding oxidoreductase activity quinate/shikimate dehydrogenase activity
2gagB heterotetrameric sarcosine oxidase gamma-subunit heterotetrameric sarcosine oxidase delta-subunit heterotetrameric sarcosine oxidase beta-subunit heterotetrameric sarcosine oxidase alpha-subunit	[pdb]	1.8 0.00267	174^ARG 60^ALA 59^HIS 56^ARG 55^GLU 358^PHE	0.0.0.0	glycine catabolic process tetrahydrofolate metabolic process tetrahydrofolate metabolic process	cytoplasm	aminomethyltransferase activity sarcosine oxidase activity sarcosine oxidase activity
1yobB flavodoxin 2	[pdb]	1.81 0.00267	131^ASP 95^GLY 148^GLY 128^TRP 126^GLY 135^PHE	0.0.0.0	transport nitrogen fixation electron transport chain oxidation-reduction process		iron ion binding electron carrier activity FMN binding oxidoreductase activity
3ad7B subunit beta of sarcosine oxidase subunit alpha of sarocosine oxidase subunit gamma of sarcosine oxidase subunit delta of sarcosine oxidase	[pdb]	1.81 0.00288	173^ILE 59^HIS 58^VAL 55^GLU 54^ALA 357^PHE	0.0.0.0	glycine catabolic process metabolic process tetrahydrofolate metabolic process tetrahydrofolate metabolic process tetrahydrofolate metabolic process oxidation-reduction process	cytoplasm	catalytic activity aminomethyltransferase activity binding sarcosine oxidase activity sarcosine oxidase activity sarcosine oxidase activity oxidoreductase activity
1os8A trypsin	[pdb]	1.82 0.00288	194^ASP 184^GLY 226^GLY 215^TRP 216^GLY 200^PHE	3.4.21.4	proteolysis		catalytic activity serine-type endopeptidase activity peptidase activity serine-type peptidase activity hydrolase activity
3qasA undecaprenyl pyrophosphate synthase	[pdb]	1.82 0.00288	228^ASP 197^GLY 196^GLY 221^TRP 27^GLY 236^PHE		cellular cell wall organization cell cycle regulation of cell shape peptidoglycan biosynthetic process polyprenol biosynthetic process cell division	cytoplasm	di-trans,poly-cis-decaprenylcistransferase activity transferase activity transferase activity
3cn7A carboxylesterase	[pdb]	1.82 0.00288	88^ASP 111^GLY 115^GLY 66^TRP 21^GLY 124^PHE	0.0.0.0			hydrolase activity
3beuB trypsin	[pdb]	1.82 0.00299	194^ASP 184^GLY 226^GLY 215^TRP 216^GLY 200^PHE	3.4.21.4	proteolysis		catalytic activity serine-type endopeptidase activity peptidase activity serine-type peptidase activity hydrolase activity
3p71C leucine carboxyl methyltransferase 1 serine/threonine-protein phosphatase 2a catalytic subunitalpha isoform	[pdb]	1.82 0.00299	57^ASP 169^GLY 168^GLY 200^TRP 217^GLY 82^PHE		inactivation of MAPK activity regulation of DNA replication protein dephosphorylation ceramide metabolic process induction of apoptosis meiosis mesoderm development RNA splicing response to organic substance second-messenger-mediated signaling regulation of Wnt receptor signaling pathway regulation of cell adhesion negative regulation of cell growth regulation of growth negative regulation of tyrosine phosphorylation of Stat3 protein regulation of cell differentiation protein modification process C-terminal protein methylation	protein phosphatase type 2A complex chromosome centromeric region spindle pole soluble fraction nucleus chromosome cytoplasm mitochondrion cytosol cytoskeleton plasma membrane microtubule cytoskeleton	phosphoprotein phosphatase activity protein binding protein C-terminus binding hydrolase activity metal ion binding protein C-terminal carboxyl O-methyltransferase activity protein binding methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity transferase activity
1wpxB carboxypeptidase y carboxypeptidase y inhibitor	[pdb]	1.82 0.00299	597^ASP 698^GLY 696^GLY 688^TRP 689^GLY 713^PHE	0.0.0.0	regulation of proteolysis regulation of Ras protein signal transduction proteolysis vacuolar protein catabolic process phytochelatin biosynthetic process	fungal-type vacuole lumen fungal-type vacuole membrane cytoplasm fungal-type vacuole fungal-type vacuole lumen cytoplasm vacuole endoplasmic reticulum	serine-type endopeptidase inhibitor activity phospholipid binding peptidase inhibitor activity carboxypeptidase activity serine-type carboxypeptidase activity protein binding peptidase activity hydrolase activity
3lxqA uncharacterized protein vp1736	[pdb]	1.83 0.00299	386^ASP 380^GLY 381^GLY 415^TRP 416^GLY 393^PHE	0.0.0.0	metabolic process		catalytic activity sulfuric ester hydrolase activity
1fiwA beta-acrosin light chain beta-acrosin heavy chain	[pdb]	1.83 0.0031	21^ASP 197^GLY 140^GLY 141^TRP 193^GLY 117^PHE	3.4.21.10	proteolysis activation of adenylate cyclase activity single fertilization acrosome reaction penetration of zona pellucida	acrosomal vesicle	catalytic activity amidase activity serine-type endopeptidase activity mannose binding drug binding peptidase activity serine-type peptidase activity hydrolase activity fucose binding
3k8pD dsl1 protein transport protein sec39	[pdb]	1.84 0.0031	216^ASP 225^GLY 164^GLY 161^TRP 160^GLY 194^PHE	0.0.0.0	transport retrograde vesicle-mediated transport Golgi to ER protein transport vesicle-mediated transport	nuclear envelope endoplasmic reticulum endoplasmic reticulum membrane membrane Dsl1p complex peroxisome	protein binding protein binding
1itxA glycosyl hydrolase	[pdb]	1.84 0.00334	280^ASP 363^GLY 341^GLY 342^TRP 359^GLY 337^PHE	3.2.1.14	polysaccharide catabolic process carbohydrate metabolic process chitin catabolic process metabolic process	extracellular region	catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds chitinase activity hydrolase activity hydrolase activity acting on glycosyl bonds
2gjxA beta-hexosaminidase beta chain beta-hexosaminidase alpha chain	[pdb]	1.85 0.00334	378^ASP 261^GLY 321^GLY 373^TRP 320^GLY 348^PHE	3.2.1.52	carbohydrate metabolic process metabolic process skeletal system development carbohydrate metabolic process N-acetylglucosamine metabolic process glycosphingolipid metabolic process ganglioside catabolic process cellular calcium ion homeostasis lysosome organization single fertilization penetration of zona pellucida sensory perception of sound locomotory behavior male courtship behavior metabolic process phospholipid biosynthetic process oligosaccharide catabolic process lipid storage sexual reproduction glycosaminoglycan metabolic process regulation of cellular metabolic process myelination cellular protein metabolic process oogenesis neuromuscular process controlling balance neuromuscular process	lysosome acrosomal vesicle soluble fraction lysosome membrane	catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds beta-N-acetylhexosaminidase activity protein binding hydrolase activity hydrolase activity acting on glycosyl bonds cation binding protein heterodimerization activity catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds beta-N-acetylhexosaminidase activity sugar binding hexosaminidase activity beta-N-acetylglucosaminidase activity hydrolase activity hydrolase activity
1btpA beta-trypsin	[pdb]	1.85 0.00334	71^ASP 43^GLY 140^GLY 141^TRP 142^GLY 82^PHE	3.4.21.4	proteolysis digestion	extracellular region extracellular space	catalytic activity serine-type endopeptidase activity protein binding peptidase activity serine-type peptidase activity hydrolase activity metal ion binding
1zyoA serine protease	[pdb]	1.85 0.00334	216^ASP 165^GLY 285^GLY 283^TRP 282^GLY 314^PHE	0.0.0.0			catalytic activity
2z5lA tylactone synthase starter module and modules 1& 2	[pdb]	1.85 0.00346	391^ASP 381^GLY 146^GLY 145^TRP 148^GLY 368^PHE	0.0.0.0	metabolic process biosynthetic process		acyl carrier activity catalytic activity binding transferase activity phosphopantetheine binding cofactor binding
1yeyB l-fuconate dehydratase	[pdb]	1.86 0.00358	29^ASP 353^GLY 22^GLY 194^TRP 193^GLY 14^PHE	0.0.0.0	metabolic process		catalytic activity metal ion binding
3ldfA putative uncharacterized protein smu.776	[pdb]	1.87 0.00359	372^ASP 109^GLY 108^GLY 60^TRP 59^GLY 366^PHE	0.0.0.0
2vrqC alpha-l-arabinofuranosidase	[pdb]	1.87 0.00371	191^ASP 131^GLY 181^GLY 178^TRP 179^GLY 196^PHE	0.0.0.0	metabolic process L-arabinose metabolic process		hydrolase activity hydrolase activity acting on glycosyl bonds
3c3yB o-methyltransferase	[pdb]	1.87 0.00371	154^ASP 227^GLY 229^GLY 184^TRP 185^GLY 232^PHE	0.0.0.0			methyltransferase activity O-methyltransferase activity transferase activity caffeoyl-CoA O-methyltransferase activity
3dc0A alpha-amylase	[pdb]	1.87 0.00371	269^ASP 310^GLY 311^GLY 280^TRP 313^GLY 303^PHE	0.0.0.0	carbohydrate metabolic process metabolic process		catalytic activity alpha-amylase activity hydrolase activity hydrolase activity acting on glycosyl bonds
1y0gA protein ycei	[pdb]	1.87 0.00384	28^ASP 144^GLY 150^GLY 148^TRP 149^GLY 59^PHE	0.0.0.0		periplasmic space
1a88A chloroperoxidase l	[pdb]	1.88 0.00384	70^ASP 94^GLY 98^GLY 30^TRP 29^GLY 207^PHE	1.11.1.10	oxidation-reduction process		catalytic activity peroxidase activity oxidoreductase activity chloride peroxidase activity
2gbwA biphenyl 2,3-dioxygenase beta subunit biphenyl 2,3-dioxygenase alpha subunit	[pdb]	1.88 0.00384	359^HOH 205^HOH 209^HOH 210^HOH 228^HOH 350^HOH	0.0.0.0	cellular aromatic compound metabolic process oxidation-reduction process cellular aromatic compound metabolic process aromatic compound catabolic process oxidation-reduction process		catalytic activity oxidoreductase activity acting on single donors with incorporation of molecular oxygen incorporation of two atoms of oxygen iron ion binding oxidoreductase activity oxidoreductase activity acting on single donors with incorporation of molecular oxygen incorporation of two atoms of oxygen oxidoreductase activity
2y42D 3-isopropylmalate dehydrogenase	[pdb]	1.88 0.00398	47^ASP 10^GLY 73^GLY 77^TRP 74^GLY 39^PHE	1.1.1.85	cellular amino acid biosynthetic process branched chain family amino acid biosynthetic process leucine biosynthetic process oxidation-reduction process	cytoplasm	magnesium ion binding 3-isopropylmalate dehydrogenase activity oxidoreductase activity oxidoreductase activity acting on the CH-OH group of donors NAD or NADP as acceptor
3hmuB aminotransferase, class iii	[pdb]	1.88 0.00398	261^ASP 291^GLY 266^GLY 273^TRP 268^GLY 119^PHE	0.0.0.0			catalytic activity transaminase activity transferase activity pyridoxal phosphate binding
3c8oB regulator of ribonuclease activity a	[pdb]	1.89 0.00411	106^ASP 33^GLY 89^GLY 87^TRP 56^GLY 26^PHE	0.0.0.0	regulation of RNA metabolic process		ribonuclease inhibitor activity
1a8sA chloroperoxidase f	[pdb]	1.89 0.00411	68^ASP 92^GLY 96^GLY 28^TRP 27^GLY 205^PHE	1.11.1.10	oxidation-reduction process		catalytic activity peroxidase activity oxidoreductase activity chloride peroxidase activity
1biyA lactoferrin	[pdb]	1.89 0.00411	162^ASP 191^GLY 118^GLY 125^TRP 124^GLY 41^PHE	0.0.0.0	transport ion transport iron ion transport cellular iron ion homeostasis	extracellular region	ferric iron binding peptidase activity serine-type peptidase activity hydrolase activity metal ion binding
1zoiB esterase	[pdb]	1.89 0.00411	71^ASP 95^GLY 99^GLY 31^TRP 30^GLY 208^PHE	0.0.0.0
1mg5B alcohol dehydrogenase	[pdb]	1.91 0.0044	87^ASP 174^GLY 131^GLY 123^TRP 129^GLY 2^PHE	1.1.1.1	alcohol metabolic process metabolic process alcohol catabolic process behavioral response to ethanol oxidation-reduction process	lipid particle cytosol microtubule associated complex protein complex	catalytic activity alcohol dehydrogenase (NAD) activity binding oxidoreductase activity protein homodimerization activity
3ov6A beta-2-microglobulin, t-cell surface glycoprotein cd1c, t-cell surface glycoprotein cd1b	[pdb]	1.91 0.0044	1053^ASP 26^GLY 28^GLY 40^TRP 45^GLY 1056^PHE		immune response antigen processing and presentation immune response antigen processing and presentation positive regulation of T cell mediated cytotoxicity response to molecule of bacterial origin antigen processing and presentation of peptide antigen via MHC class I antigen processing and presentation of exogenous protein antigen via MHC class Ib TAP-dependent immune response response to drug	lysosome lysosomal membrane endosome plasma membrane endosome membrane membrane integral to membrane endosome plasma membrane integral to plasma membrane endosome membrane membrane integral to membrane Golgi membrane extracellular region extracellular space plasma membrane external side of plasma membrane early endosome membrane MHC class I protein complex	protein binding protein binding
1r76A pectate lyase	[pdb]	1.91 0.00455	383^ASP 293^GLY 291^GLY 346^TRP 343^GLY 389^PHE	0.0.0.0			lyase activity
1yu0A major tropism determinant (mtd-p1)	[pdb]	1.91 0.00455	214^ASP 342^GLY 343^GLY 345^TRP 304^GLY 364^PHE	0.0.0.0			binding
2ghsA agr_c_1268p	[pdb]	1.91 0.00455	242^ASP 258^GLY 239^GLY 236^TRP 237^GLY 24^PHE	0.0.0.0
3llcA putative hydrolase	[pdb]	1.91 0.00455	147^ASP 44^GLY 115^GLY 117^TRP 111^GLY 184^PHE	0.0.0.0
1dx9A flavodoxin	[pdb]	1.92 0.00455	123^ASP 87^GLY 140^GLY 120^TRP 118^GLY 127^PHE	0.0.0.0	transport cellular response to iron ion starvation electron transport chain oxidation-reduction process transport electron transport chain		protein binding electron carrier activity FMN binding oxidoreductase activity electron carrier activity FMN binding oxidoreductase activity
3dcmX uncharacterized protein tm_1570	[pdb]	1.92 0.00455	148^ASP 141^GLY 145^GLY 144^TRP 143^GLY 109^PHE	0.0.0.0
2paaA phosphoglycerate kinase, testis specific	[pdb]	1.92 0.00455	314^ASP 305^GLY 253^GLY 310^TRP 309^GLY 281^PHE	2.7.2.3	glycolysis phosphorylation	cytoplasm	nucleotide binding phosphoglycerate kinase activity ATP binding kinase activity transferase activity
1q5xC regulator of rnase e activity a	[pdb]	1.92 0.0047	106^ASP 33^GLY 89^GLY 87^TRP 56^GLY 26^PHE	0.0.0.0	RNA catabolic process regulation of catalytic activity regulation of RNA metabolic process		protein binding ribonuclease inhibitor activity
2ecfA dipeptidyl peptidase iv	[pdb]	1.92 0.0047	541^ASP 630^GLY 608^GLY 609^TRP 613^GLY 556^PHE	0.0.0.0	proteolysis	membrane
2og1A 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoatehydrolase	[pdb]	1.92 0.0047	83^ASP 114^GLY 87^GLY 216^TRP 139^GLY 20^PHE	3.7.1.8	aromatic compound catabolic process		catalytic activity hydrolase activity hydrolase activity acting on acid carbon-carbon bonds
1iryA hmth1	[pdb]	1.92 0.0047	119^ASP 36^GLY 34^GLY 32^TRP 21^GLY 133^PHE	0.0.0.0	purine nucleotide catabolic process dGTP catabolic process DNA repair response to oxidative stress DNA protection	cytoplasm	GTPase activity protein binding 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity hydrolase activity 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity
1op2A venom serine proteinase	[pdb]	1.92 0.0047	23^ASP 197^GLY 140^GLY 141^TRP 142^GLY 29^PHE	0.0.0.0	proteolysis pathogenesis	extracellular region	catalytic activity serine-type endopeptidase activity peptidase activity serine-type peptidase activity hydrolase activity
2w5wB alkaline phosphatase	[pdb]	1.92 0.0047	83^ASP 46^GLY 44^GLY 260^TRP 261^GLY 91^PHE	0.0.0.0	metabolic process		catalytic activity phosphatase activity
3k7dB glutamate-ammonia-ligase adenylyltransferase	[pdb]	1.93 0.00486	701^ASP 687^GLY 692^GLY 694^TRP 693^GLY 739^PHE	0.0.0.0			nucleotide binding ATP binding [glutamate-ammonia-ligase] adenylyltransferase activity transferase activity nucleotidyltransferase activity
2z3zA dipeptidyl aminopeptidase iv	[pdb]	1.93 0.00486	538^ASP 623^GLY 601^GLY 602^TRP 626^GLY 549^PHE	0.0.0.0	proteolysis	membrane	aminopeptidase activity peptidase activity serine-type peptidase activity hydrolase activity
1yiqA quinohemoprotein alcohol dehydrogenase	[pdb]	1.93 0.00486	495^ASP 618^GLY 540^GLY 539^TRP 61^GLY 683^PHE	0.0.0.0	oxidation-reduction process	membrane	iron ion binding calcium ion binding electron carrier activity oxidoreductase activity acting on CH-OH group of donors
3nomA glutamine cyclotransferase	[pdb]	1.93 0.00486	126^ASP 101^GLY 129^GLY 104^TRP 89^GLY 150^PHE	0.0.0.0			transferase activity
3nreB aldose 1-epimerase	[pdb]	1.93 0.00502	44^ASP 20^GLY 19^GLY 87^TRP 89^GLY 151^PHE	0.0.0.0	carbohydrate metabolic process		catalytic activity isomerase activity carbohydrate binding
2z8dB galacto-n-biose/lacto-n-biose i transportersubstrate-binding protein	[pdb]	1.94 0.00502	233^ASP 311^GLY 213^GLY 218^TRP 217^GLY 241^PHE	0.0.0.0	transport		transporter activity
1elvA complement c1s component	[pdb]	1.94 0.00502	430^ASP 426^GLY 554^GLY 555^TRP 556^GLY 417^PHE	3.4.21.42	proteolysis complement activation classical pathway glial cell differentiation innate immune response	extracellular region	catalytic activity serine-type endopeptidase activity calcium ion binding peptidase activity serine-type peptidase activity hydrolase activity metal ion binding
2pz1A rho guanine nucleotide exchange factor 4	[pdb]	1.94 0.00518	539^ASP 239^GLY 241^GLY 242^TRP 234^GLY 521^PHE	0.0.0.0	apoptosis induction of apoptosis by extracellular signals regulation of Rho protein signal transduction	intracellular cytoplasm cytosol plasma membrane membrane ruffle membrane cell projection	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity protein binding protein domain specific binding
3hbxF glutamate decarboxylase 1	[pdb]	1.95 0.00535	244^ASP 275^GLY 286^GLY 287^TRP 122^GLY 63^PHE	4.1.1.15	glutamate metabolic process carboxylic acid metabolic process response to cadmium ion		catalytic activity glutamate decarboxylase activity calmodulin binding lyase activity carboxy-lyase activity pyridoxal phosphate binding
1xkvA atp-dependent phosphoenolpyruvate carboxykinase	[pdb]	1.95 0.00535	496^ASP 351^GLY 431^GLY 489^TRP 430^GLY 467^PHE	4.1.1.49	gluconeogenesis	cytoplasm	nucleotide binding phosphoenolpyruvate carboxykinase activity phosphoenolpyruvate carboxykinase (ATP) activity ATP binding lyase activity carboxy-lyase activity purine nucleotide binding metal ion binding
2g6wA 8-amino-7-oxononanoate synthase	[pdb]	1.95 0.00535	204^ASP 210^GLY 218^GLY 221^TRP 213^GLY 105^PHE	2.3.1.47	metabolic process biosynthetic process biotin biosynthetic process		catalytic activity 8-amino-7-oxononanoate synthase activity transferase activity transferase activity transferring nitrogenous groups
1tz9B mannonate dehydratase	[pdb]	1.95 0.00535	317^ASP 63^GLY 4^GLY 3^TRP 28^GLY 244^PHE	4.2.1.8	glucuronate catabolic process		mannonate dehydratase activity lyase activity
1cx8D transferrin receptor protein	[pdb]	1.96 0.00552	184^ASP 306^GLY 462^GLY 453^TRP 456^GLY 316^PHE	0.0.0.0	response to hypoxia proteolysis cellular iron ion homeostasis endocytosis acute-phase response aging response to nutrient response to organic substance response to inorganic substance response to iron ion response to manganese ion response to retinoic acid interspecies interaction between organisms response to copper ion	extracellular region mitochondrion endosome plasma membrane integral to plasma membrane coated pit membrane integral to membrane cytoplasmic membrane-bounded vesicle melanosome perinuclear region of cytoplasm extracellular vesicular exosome	receptor activity transferrin receptor activity peptidase activity
1xvoA trypsin	[pdb]	1.96 0.00552	26^ASP 197^GLY 137^GLY 138^TRP 139^GLY 29^PHE	3.4.21.4	proteolysis	extracellular region	catalytic activity serine-type endopeptidase activity peptidase activity serine-type peptidase activity hydrolase activity
3nk2X 6-hydroxy-l-nicotine oxidase	[pdb]	1.96 0.00552	360^ASP 282^GLY 283^GLY 371^TRP 406^GLY 332^PHE		oxidation-reduction process		oxidoreductase activity
1a0cA xylose isomerase	[pdb]	1.96 0.00552	245^ASP 192^GLY 188^GLY 187^TRP 189^GLY 252^PHE	5.3.1.5	carbohydrate metabolic process pentose-phosphate shunt D-xylose metabolic process	cytoplasm	xylose isomerase activity isomerase activity metal ion binding
1lquA fpra	[pdb]	1.96 0.00552	109^ASP 47^GLY 105^GLY 359^TRP 358^GLY 138^PHE	1.18.1.2	metabolic process oxidation-reduction process		catalytic activity ferredoxin-NADP+ reductase activity binding ferredoxin-NAD+ reductase activity oxidoreductase activity flavin adenine dinucleotide binding NADP+ binding
1xvyA sfua	[pdb]	1.96 0.00552	290^ASP 97^GLY 229^GLY 95^TRP 231^GLY 224^PHE	0.0.0.0	transport ion transport iron ion transport	periplasmic space	transporter activity metal ion binding
1q3xB mannan-binding lectin serine protease 2	[pdb]	1.96 0.00552	589^ASP 634^GLY 572^GLY 573^TRP 574^GLY 648^PHE	3.4.21.104	complement activation lectin pathway proteolysis complement activation	extracellular region	catalytic activity serine-type endopeptidase activity calcium ion binding protein binding peptidase activity serine-type peptidase activity hydrolase activity metal ion binding calcium-dependent protein binding
1fwiC urease	[pdb]	1.97 0.00569	360^ASP 164^GLY 158^GLY 137^TRP 160^GLY 271^PHE	3.5.1.5	nitrogen compound metabolic process urea metabolic process nitrogen compound metabolic process nitrogen compound metabolic process urea metabolic process	cytoplasm cytoplasm cytoplasm	urease activity nickel ion binding hydrolase activity urease activity nickel ion binding hydrolase activity urease activity nickel ion binding hydrolase activity hydrolase activity acting on carbon-nitrogen (but not peptide) bonds
1kp9B cyclopropane-fatty-acyl-phospholipid synthase 1	[pdb]	1.97 0.00587	20^ASP 72^GLY 74^GLY 75^TRP 76^GLY 139^PHE	2.1.1.79	lipid biosynthetic process S-adenosylmethionine metabolic process Actinobacterium-type cell wall biogenesis mycolic acid biosynthetic process lipid biosynthetic process	cytoplasm plasma membrane cytoplasm	methyltransferase activity cyclopropane-fatty-acyl-phospholipid synthase activity transferase activity methyltransferase activity cyclopropane-fatty-acyl-phospholipid synthase activity transferase activity
2z37B chitinase	[pdb]	1.98 0.00588	360^ASP 223^GLY 216^GLY 217^TRP 219^GLY 206^PHE	0.0.0.0	chitin catabolic process cell wall macromolecule catabolic process		chitinase activity chitin binding
2idaA hypothetical protein	[pdb]	1.98 0.00588	81^ASP 68^GLY 76^GLY 75^TRP 74^GLY 58^PHE	0.0.0.0			zinc ion binding
1ac5A kex1(delta)p	[pdb]	1.98 0.00606	393^ASP 211^GLY 213^GLY 214^TRP 179^GLY 227^PHE	3.4.16.6	proteolysis protein processing	trans-Golgi network membrane integral to membrane	carboxypeptidase activity serine-type carboxypeptidase activity protein binding peptidase activity hydrolase activity identical protein binding
3fr7A putative ketol-acid reductoisomerase(os05g0573700 protein)	[pdb]	1.99 0.00625	397^HOH 318^HOH 321^GLY 528^TRP 524^HOH 392^HOH	0.0.0.0	metabolic process cellular amino acid biosynthetic process branched chain family amino acid biosynthetic process oxidation-reduction process	chloroplast plastid	magnesium ion binding catalytic activity ketol-acid reductoisomerase activity binding oxidoreductase activity protein homodimerization activity metal ion binding coenzyme binding NADPH binding
3nigA mmonoclonal antibody 10e5 heavy chain integrin alpha-iib mmonoclonal antibody 10e5 light chain integrin beta-3	[pdb]	1.99 0.00625	232^CYS 188^ARG 193^THR 235^LYS 236^ILE 160^LEU	0.0.0.0	positive regulation of protein phosphorylation positive regulation of endothelial cell proliferation cell-substrate junction assembly cell adhesion cell-matrix adhesion integrin-mediated signaling pathway multicellular organismal development blood coagulation positive regulation of endothelial cell migration negative regulation of macrophage derived foam cell differentiation negative regulation of lipid storage smooth muscle cell migration regulation of cell migration positive regulation of vascular endothelial growth factor receptor signaling pathway activation of protein kinase activity negative regulation of lipid transport tube development wound healing interspecies interaction between organisms regulation of bone resorption negative regulation of low-density lipoprotein particle receptor biosynthetic process positive regulation of peptidyl-tyrosine phosphorylation negative regulation of lipoprotein metabolic process angiogenesis involved in wound healing cell adhesion cell-matrix adhesion integrin-mediated signaling pathway	plasma membrane integral to plasma membrane integrin complex external side of plasma membrane membrane integral to membrane platelet alpha granule membrane alphav-beta3 integrin-vitronectin complex plasma membrane integral to plasma membrane focal adhesion integrin complex external side of plasma membrane membrane integral to membrane platelet alpha granule membrane	receptor activity platelet-derived growth factor receptor binding integrin binding binding protein binding identical protein binding vascular endothelial growth factor receptor 2 binding cell adhesion molecule binding receptor activity identical protein binding extracellular matrix binding
3a0hB photosystem ii reaction center protein z cytochrome b559 subunit beta photosystem ii reaction center protein x photosystem ii reaction center protein y photosystem ii cp43 protein cytochrome b559 subunit alpha photosystem ii core light harvesting protein photosystem ii reaction center protein m photosystem ii reaction center protein ycf12 photosystem ii reaction center protein t cytochrome c-550 photosystem ii manganese-stabilizing polypeptide photosystem ii reaction center protein k photosystem ii reaction center protein h photosystem ii reaction center protein i photosystem ii reaction center protein l photosystem ii 12 kda extrinsic protein photosystem q(b) protein photosystem ii d2 protein photosystem ii reaction center protein j	[pdb]	1.99 0.00625	313^THR 403^SER 342^PRO 340^VAL 404^LEU 355^THR	0.0.0.0	transport photosynthetic electron transport chain photosynthesis photosynthesis light reaction electron transport chain photosynthesis photosynthesis photosynthesis light reaction photosynthesis protein stabilization photosynthetic electron transport chain photosynthetic electron transport in photosystem II photosynthesis light reaction photosynthesis photosynthesis photosynthetic electron transport chain photosynthesis light reaction photosynthetic electron transport in photosystem II photosynthesis photosynthesis light reaction photosynthesis photosystem II stabilization photosynthesis photosystem II stabilization transport response to herbicide photosynthetic electron transport in photosystem II photosynthesis photosynthesis light reaction electron transport chain transport photosynthesis electron transport chain photosystem II stabilization photosynthesis transport photosynthesis electron transport chain respiratory electron transport chain oxidation-reduction process transport	photosystem II plastid photosystem II reaction center thylakoid membrane integral to membrane plasma membrane-derived thylakoid photosystem II thylakoid membrane photosystem II photosystem II reaction center thylakoid membrane integral to membrane thylakoid membrane photosystem II thylakoid membrane integral to membrane thylakoid membrane photosystem II membrane thylakoid membrane photosystem membrane light-harvesting complex photosystem II photosystem II reaction center photosystem II membrane integral to membrane photosystem membrane membrane light-harvesting complex plasma membrane light-harvesting complex oxygen evolving complex extrinsic to membrane photosystem II photosystem II reaction center thylakoid membrane integral to membrane thylakoid membrane photosystem II thylakoid membrane integral to membrane light-harvesting complex plasma membrane light-harvesting complex thylakoid membrane photosystem II thylakoid oxygen evolving complex membrane extrinsic to membrane thylakoid membrane photosystem II photosystem II reaction center thylakoid membrane integral to membrane thylakoid membrane photosystem II thylakoid membrane thylakoid membrane photosystem II plastid photosystem II reaction center thylakoid membrane integral to membrane thylakoid membrane photosystem II photosystem II reaction center thylakoid membrane integral to membrane thylakoid membrane photosystem II photosystem II reaction center thylakoid membrane integral to membrane thylakoid membrane	heme binding metal ion binding phosphate binding chlorophyll binding electron transporter transferring electrons within the cyclic electron transport pathway of photosynthesis activity chlorophyll binding iron ion binding electron carrier activity electron transporter transferring electrons within the cyclic electron transport pathway of photosynthesis activity calcium ion binding electron transporter transferring electrons within the cyclic electron transport pathway of photosynthesis activity metal ion binding iron ion binding electron carrier activity heme binding
3lfiA fructosyltransferase	[pdb]	1.99 0.00625	402^ASP 59^GLY 419^GLY 417^TRP 56^GLY 366^PHE	0.0.0.0	carbohydrate metabolic process metabolic process		hydrolase activity hydrolyzing O-glycosyl compounds hydrolase activity
1kv9A type ii quinohemoprotein alcohol dehydrogenase	[pdb]	1.99 0.00645	265^ASP 178^GLY 227^GLY 223^TRP 199^GLY 296^PHE	0.0.0.0	oxidation-reduction process	membrane outer membrane-bounded periplasmic space	iron ion binding calcium ion binding electron carrier activity oxidoreductase activity acting on CH-OH group of donors
2dx1A rho guanine nucleotide exchange factor 4	[pdb]	1.99 0.00645	138^ASP 168^GLY 170^GLY 171^TRP 163^GLY 451^PHE	0.0.0.0	apoptosis induction of apoptosis by extracellular signals regulation of Rho protein signal transduction	intracellular cytoplasm cytosol plasma membrane membrane ruffle membrane cell projection	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity protein binding protein domain specific binding
3icfA serine/threonine-protein phosphatase t	[pdb]	2 0.00645	278^ASP 361^GLY 360^GLY 393^TRP 410^GLY 305^PHE	3.1.3.16	protein dephosphorylation	nucleus cytoplasm	phosphoprotein phosphatase activity protein serine/threonine phosphatase activity binding hydrolase activity metal ion binding
3i5tA aminotransferase	[pdb]	2 0.00645	258^ASP 289^GLY 263^GLY 270^TRP 265^GLY 116^PHE	0.0.0.0			catalytic activity transaminase activity transferase activity pyridoxal phosphate binding
3i8bA xylulose kinase	[pdb]	2 0.00645	22^ASP 463^GLY 280^GLY 481^TRP 282^GLY 31^PHE	0.0.0.0	carbohydrate metabolic process xylulose metabolic process		xylulokinase activity kinase activity transferase activity phosphotransferase activity
2f91A serine protease inhibitor i/ii hepatopancreas trypsin	[pdb]	2 0.00664	21^PRO 197^GLY 140^GLY 141^TRP 193^HOH 27^CYS	0.0.0.0	proteolysis	extracellular region	serine-type endopeptidase inhibitor activity peptidase inhibitor activity catalytic activity serine-type endopeptidase activity peptidase activity serine-type peptidase activity hydrolase activity
3b9tB twin-arginine translocation pathway signalprotein	[pdb]	2.01 0.00664	140^ASP 155^GLY 143^GLY 84^TRP 85^GLY 253^PHE	0.0.0.0	metabolic process		hydrolase activity
3qokA putative chitinase ii	[pdb]	2.01 0.00685	223^ASP 112^GLY 113^GLY 114^TRP 115^GLY 394^PHE		carbohydrate metabolic process chitin catabolic process metabolic process		catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds chitinase activity hydrolase activity hydrolase activity
2cznA chitinase	[pdb]	2.02 0.00705	281^ASP 340^GLY 277^GLY 274^TRP 275^GLY 307^PHE	0.0.0.0	carbohydrate metabolic process		catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds carbohydrate binding polysaccharide binding
3eooO methylisocitrate lyase	[pdb]	2.02 0.00705	88^ASP 121^GLY 92^GLY 93^TRP 94^GLY 188^PHE	0.0.0.0	metabolic process		catalytic activity lyase activity methylisocitrate lyase activity
1lzlA heroin esterase	[pdb]	2.02 0.00705	132^ASP 164^GLY 162^GLY 84^TRP 158^GLY 126^PHE	0.0.0.0
1clkA xylose isomerase	[pdb]	2.03 0.00727	56^ASP 31^GLY 18^GLY 19^TRP 21^GLY 74^PHE	5.3.1.5	carbohydrate metabolic process pentose-phosphate shunt D-xylose metabolic process	cytoplasm	xylose isomerase activity isomerase activity metal ion binding
2dcaA cathepsin b	[pdb]	2.02 0.00727	22^ASP 218^GLY 229^GLY 225^TRP 226^GLY 32^PHE	3.4.22.1	proteolysis regulation of catalytic activity	mitochondrion lysosome melanosome	cysteine-type endopeptidase activity protein binding peptidase activity cysteine-type peptidase activity hydrolase activity
3ktdB prephenate dehydrogenase	[pdb]	2.03 0.00727	25^ASP 14^GLY 16^GLY 133^TRP 132^GLY 34^PHE	0.0.0.0	tyrosine biosynthetic process metabolic process		catalytic activity prephenate dehydrogenase (NADP+) activity binding oxidoreductase activity
1g5bB serine/threonine protein phosphatase	[pdb]	2.03 0.00727	49^ASP 99^GLY 98^GLY 93^TRP 83^GLY 207^PHE	3.1.3.16			phosphoprotein phosphatase activity hydrolase activity metal ion binding
2b9lA prophenoloxidase activating factor	[pdb]	2.03 0.00727	334^ASP 381^GLY 379^GLY 376^TRP 377^GLY 331^PHE	0.0.0.0	proteolysis		catalytic activity serine-type endopeptidase activity
2b9vP alpha-amino acid ester hydrolase	[pdb]	2.03 0.00749	571^ASP 234^GLY 237^GLY 343^TRP 344^GLY 573^PHE	0.0.0.0	metabolic process		dipeptidyl-peptidase activity hydrolase activity alpha-amino-acid esterase activity
1d0lA 35kd soluble lytic transglycosylase	[pdb]	2.03 0.00749	208^ASP 215^GLY 222^GLY 247^TRP 166^GLY 199^PHE	0.0.0.0	cytokinesis cellular cell wall organization peptidoglycan biosynthetic process	plasma membrane cell outer membrane membrane	lytic transglycosylase activity lyase activity carbon-oxygen lyase activity
1a0dC xylose isomerase	[pdb]	2.04 0.00749	243^ASP 190^GLY 186^GLY 185^TRP 187^GLY 250^PHE	5.3.1.5	carbohydrate metabolic process pentose-phosphate shunt D-xylose metabolic process	cytoplasm	xylose isomerase activity isomerase activity metal ion binding
3eptA rebc	[pdb]	2.04 0.00772	79^ASP 236^GLY 234^GLY 72^TRP 71^GLY 218^PHE	0.0.0.0	metabolic process oxidation-reduction process		monooxygenase activity oxidoreductase activity
3ddmD putative mandelate racemase/muconate lactonizingenzyme	[pdb]	2.05 0.00795	373^ASP 315^GLY 55^GLY 54^TRP 53^GLY 20^PHE	0.0.0.0	metabolic process cellular amino acid catabolic process		catalytic activity
3b7fA glycosyl hydrolase, bnr repeat	[pdb]	2.05 0.00795	157^ASP 167^GLY 166^GLY 164^TRP 230^GLY 101^PHE	0.0.0.0			hydrolase activity
3eq8A prolyl endopeptidase	[pdb]	2.05 0.00795	356^ASP 474^GLY 506^GLY 514^TRP 517^GLY 453^PHE	3.4.21.26	proteolysis	nucleus cytoplasm	serine-type endopeptidase activity peptidase activity serine-type peptidase activity hydrolase activity
3hhiA cathepsin b-like cysteine protease	[pdb]	2.05 0.00795	115^ASP 161^GLY 164^GLY 123^TRP 165^GLY 208^PHE	0.0.0.0	proteolysis		cysteine-type endopeptidase activity peptidase activity cysteine-type peptidase activity hydrolase activity
1eu8A trehalose/maltose binding protein	[pdb]	2.05 0.00795	123^ASP 324^GLY 330^GLY 261^TRP 262^GLY 101^PHE	0.0.0.0	transport		transporter activity
2uveB exopolygalacturonase	[pdb]	2.05 0.00795	381^ASP 219^GLY 273^GLY 274^TRP 305^GLY 347^PHE	0.0.0.0
2h7cE liver carboxylesterase 1	[pdb]	2.05 0.00819	5115^ASP 5190^GLY 5176^GLY 5175^TRP 5173^GLY 5055^PHE	3.1.1.1	metabolic process response to toxin	endoplasmic reticulum endoplasmic reticulum lumen	carboxylesterase activity hydrolase activity