The LabelHash Server

Top 150 matches

For each match you can click on the "[pdb]" link to download a PDB file with the matching chain aligned with the motif.
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PDB ID		LRMSD / p-value	Matching Residues	EC	Gene Ontology annotations
PDB ID		LRMSD / p-value	Matching Residues	EC	Biological Process	Cellular Component	Molecular Function
3b54B nucleoside diphosphate kinase	[pdb]	1.23 8.97e-05	13^LYS 14^PRO 93^GLY 106^ARG 116^ASN 120^GLY	2.7.4.6	nucleoside diphosphate phosphorylation GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process DNA repair response to DNA damage stimulus nucleotide metabolic process nucleoside triphosphate biosynthetic process	cytoplasm mitochondrion mitochondrial intermembrane space cytosol	nucleotide binding nucleoside diphosphate kinase activity protein binding ATP binding kinase activity transferase activity identical protein binding metal ion binding
3pihA dna (32-mer) uvrabc system protein a	[pdb]	1.27 0.000154	698^LYS 695^PRO 713^GLY 706^ARG 703^ASN 701^GLY	0.0.0.0	DNA repair nucleotide-excision repair response to DNA damage stimulus SOS response	cytoplasm excinuclease repair complex	nucleotide binding DNA binding catalytic activity nuclease activity ATP binding excinuclease ABC activity ATPase activity nucleoside-triphosphatase activity metal ion binding
1ndlC nucleoside diphosphate kinase	[pdb]	1.32 0.000297	13^LYS 14^PRO 93^GLY 106^ARG 116^ASN 120^GLY	2.7.4.6	nucleoside diphosphate phosphorylation GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process protein phosphorylation microtubule-based process mitosis open tracheal system development epithelial cell migration open tracheal system nucleotide metabolic process establishment or maintenance of polarity of follicular epithelium peptidyl-serine phosphorylation adherens junction organization	cytoplasm cytoskeleton microtubule microtubule associated complex nuclear microtubule	nucleotide binding magnesium ion binding nucleoside diphosphate kinase activity ATP binding GTP binding microtubule binding kinase activity transferase activity metal ion binding
1xiqE nucleoside diphosphate kinase b	[pdb]	1.32 0.000297	9^LYS 10^PRO 89^GLY 102^ARG 112^ASN 116^GLY	0.0.0.0	GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process	cytoplasm	nucleotide binding nucleoside diphosphate kinase activity ATP binding kinase activity transferase activity
2zuaD nucleoside diphosphate kinase	[pdb]	1.33 0.000316	12^LYS 13^PRO 92^GLY 105^ARG 115^ASN 119^GLY	0.0.0.0	GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process nucleotide metabolic process	cytoplasm	nucleotide binding nucleoside diphosphate kinase activity ATP binding kinase activity transferase activity metal ion binding
1w7wD nucleoside diphosphate kinase	[pdb]	1.34 0.000336	11^LYS 12^PRO 91^GLY 104^ARG 114^ASN 118^GLY	0.0.0.0	GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process	cytoplasm	nucleotide binding nucleoside diphosphate kinase activity ATP binding kinase activity transferase activity
1sp3A cytochrome c, putative	[pdb]	1.35 0.000376	349^LYS 348^PRO 114^GLY 73^ARG 70^ASN 352^GLY	0.0.0.0
3mpdB nucleoside diphosphate kinase	[pdb]	1.35 0.000376	9^LYS 10^PRO 89^GLY 102^ARG 112^ASN 116^GLY	0.0.0.0	GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process nucleotide metabolic process		nucleotide binding nucleoside diphosphate kinase activity ATP binding kinase activity transferase activity metal ion binding
3bbcD nucleoside diphosphate kinase b	[pdb]	1.36 0.000438	12^LYS 13^PRO 92^GLY 105^ARG 115^ASN 119^GLY	2.7.4.6	GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process regulation of transcription DNA-dependent cell adhesion nucleotide metabolic process nucleoside triphosphate biosynthetic process negative regulation of apoptosis positive regulation of keratinocyte differentiation regulation of epidermis development	ruffle nucleus cytoplasm lamellipodium	nucleotide binding DNA binding sequence-specific DNA binding transcription factor activity nucleoside diphosphate kinase activity protein binding ATP binding kinase activity transferase activity metal ion binding
1nb2A nucleoside diphosphate kinase	[pdb]	1.36 0.000438	10^LYS 11^PRO 90^GLY 103^ARG 113^ASN 117^GLY	0.0.0.0	GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process	cytoplasm	nucleoside diphosphate kinase activity ATP binding
2vu5A nucleoside diphosphate kinase	[pdb]	1.37 0.000439	9^LYS 10^PRO 89^GLY 102^ARG 112^ASN 116^GLY	2.7.4.6	GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process nucleotide metabolic process	cytoplasm	nucleotide binding nucleoside diphosphate kinase activity ATP binding kinase activity transferase activity metal ion binding
1bhnE nucleoside diphosphate transferase	[pdb]	1.37 0.00046	12^LYS 13^PRO 92^GLY 105^ARG 115^ASN 119^GLY	2.7.4.6	GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process endocytosis nervous system development nucleotide metabolic process cell differentiation	nucleus cytoplasm plasma membrane membrane	nucleotide binding nucleoside diphosphate kinase activity ATP binding kinase activity transferase activity metal ion binding
1zs6A nucleoside diphosphate kinase 3	[pdb]	1.37 0.00046	29^LYS 30^PRO 109^GLY 122^ARG 132^ASN 136^GLY	2.7.4.6	GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process apoptosis induction of apoptosis nucleotide metabolic process	mitochondrion	nucleotide binding nucleoside diphosphate kinase activity ATP binding kinase activity transferase activity metal ion binding
1wklB nucleotide diphosphate kinase	[pdb]	1.38 0.000481	9^LYS 10^PRO 89^GLY 102^ARG 112^ASN 116^GLY	2.7.4.6	GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process nucleotide metabolic process	cytoplasm	nucleotide binding nucleoside diphosphate kinase activity ATP binding kinase activity transferase activity metal ion binding
1pkuJ nucleoside diphosphate kinase i	[pdb]	1.38 0.000481	12^LYS 13^PRO 92^GLY 105^ARG 115^ASN 119^GLY	2.7.4.6	GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process nucleotide metabolic process		nucleotide binding nucleoside diphosphate kinase activity ATP binding kinase activity transferase activity metal ion binding
1f6tB protein (nucleoside diphosphate kinase)	[pdb]	1.39 0.000503	16^LYS 17^PRO 96^GLY 109^ARG 119^ASN 123^GLY	2.7.4.6	GTP biosynthetic process dGDP phosphorylation dGTP biosynthetic process from dGDP UTP biosynthetic process CTP biosynthetic process translational elongation cytoskeleton organization G-protein coupled receptor protein signaling pathway nucleotide metabolic process nucleoside triphosphate biosynthetic process response to bacterium	cytoplasm ribosome cytoskeleton plasma membrane stored secretory granule phagocytic vesicle	nucleotide binding nucleoside diphosphate kinase activity ATP binding kinase activity transferase activity metal ion binding
1u8wE nucleoside diphosphate kinase i	[pdb]	1.39 0.000503	9^LYS 10^PRO 89^GLY 102^ARG 112^ASN 116^GLY	2.7.4.6	GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process nucleotide metabolic process response to salt stress response to cadmium ion	vacuole peroxisome plasma membrane chloroplast apoplast	nucleotide binding nucleoside diphosphate kinase activity ATP binding kinase activity transferase activity metal ion binding
2hveB nucleoside diphosphate kinase a	[pdb]	1.39 0.000524	12^LYS 13^PRO 92^GLY 105^ARG 115^ASN 119^GLY	2.7.4.6	GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process endocytosis nervous system development negative regulation of cell proliferation nucleotide metabolic process cell differentiation regulation of apoptosis positive regulation of DNA binding positive regulation of epithelial cell proliferation	nucleus cytoplasm	nucleotide binding magnesium ion binding deoxyribonuclease activity nucleoside diphosphate kinase activity protein binding ATP binding GTP binding kinase activity transferase activity identical protein binding metal ion binding
3pj9B nucleoside diphosphate kinase	[pdb]	1.39 0.000524	9^LYS 10^PRO 89^GLY 102^ARG 112^ASN 116^GLY		GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process nucleotide metabolic process	cytoplasm	nucleotide binding nucleoside diphosphate kinase activity protein binding ATP binding kinase activity transferase activity metal ion binding
2az3E nucleoside diphosphate kinase	[pdb]	1.41 0.000588	13^LYS 14^PRO 93^GLY 106^ARG 116^ASN 120^GLY	2.7.4.6	GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process nucleotide metabolic process	cytoplasm	nucleotide binding nucleoside diphosphate kinase activity ATP binding kinase activity transferase activity metal ion binding
1s57A nucleoside diphosphate kinase ii	[pdb]	1.46 0.000763	91^LYS 92^PRO 171^GLY 184^ARG 194^ASN 198^GLY	2.7.4.6	GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process nucleotide metabolic process response to UV red far-red light phototransduction auxin mediated signaling pathway	nucleus cytoplasm chloroplast plastid chloroplast stroma thylakoid chloroplast envelope	nucleotide binding nucleoside diphosphate kinase activity protein binding ATP binding kinase activity transferase activity identical protein binding metal ion binding
2nckL nucleoside diphosphate kinase	[pdb]	1.47 0.000763	11^LYS 12^PRO 91^GLY 104^ARG 114^ASN 118^GLY	2.7.4.6	GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process nucleotide metabolic process	cytoplasm	nucleotide binding nucleoside diphosphate kinase activity ATP binding kinase activity transferase activity metal ion binding
2hurC nucleoside diphosphate kinase	[pdb]	1.5 0.000856	11^LYS 12^PRO 91^GLY 104^ARG 114^ASN 118^GLY	2.7.4.6	GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process nucleotide metabolic process	cytoplasm	nucleotide binding nucleoside diphosphate kinase activity protein binding ATP binding kinase activity transferase activity metal ion binding
2ha1A fibronectin	[pdb]	1.51 0.00087	64^LYS 65^PRO 141^GLY 143^ARG 16^ASN 62^GLY		angiogenesis acute-phase response cell adhesion regulation of cell shape response to wounding cell migration peptide cross-linking substrate adhesion-dependent cell spreading	extracellular region fibrinogen complex proteinaceous extracellular matrix extracellular space ER-Golgi intermediate compartment extracellular matrix platelet alpha granule lumen	extracellular matrix structural constituent protein binding collagen binding heparin binding
1k44E nucleoside diphosphate kinase	[pdb]	1.51 0.00087	10^LYS 11^PRO 90^GLY 104^ARG 114^ASN 118^GLY	2.7.4.6	GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process nucleotide metabolic process protein autophosphorylation nucleic acid phosphodiester bond hydrolysis	extracellular region cytoplasm plasma membrane host cell nucleus	nucleotide binding nuclease activity nucleoside diphosphate kinase activity protein binding ATP binding kinase activity transferase activity metal ion binding endonuclease activity uracil DNA N-glycosylase activity
2vf7B excinuclease abc, subunit a.	[pdb]	1.65 0.00107	623^LYS 620^PRO 638^GLY 631^ARG 628^ASN 626^GLY	0.0.0.0	DNA repair nucleotide-excision repair response to DNA damage stimulus SOS response	cytoplasm excinuclease repair complex	nucleotide binding DNA binding nuclease activity ATP binding excinuclease ABC activity ATPase activity metal ion binding
2d3cE glutamine synthetase	[pdb]	1.7 0.00112	237^LYS 238^PRO 312^GLY 295^ARG 244^ASN 247^GLY	6.3.1.2	glutamine biosynthetic process nitrogen compound metabolic process	cytoplasm	nucleotide binding catalytic activity glutamate-ammonia ligase activity ATP binding ligase activity
2wv9A flavivirin protease ns2b regulatory subunit,flavivirin protease ns3 catalytic subunit	[pdb]	1.72 0.00116	399^LYS 396^PRO 463^GLY 461^ARG 417^ASN 419^GLY	3.4.21.91, 2.7.7.48	transcription RNA-dependent viral reproduction RNA metabolic process viral infectious cycle viral genome replication evasion by virus of host immune response methylation	membrane integral to membrane virion viral nucleocapsid viral capsid viral envelope host cell membrane virion part	nucleotide binding nucleic acid binding RNA binding RNA helicase activity double-stranded RNA binding catalytic activity RNA-directed RNA polymerase activity serine-type endopeptidase activity helicase activity mRNA (guanine-N7-)-methyltransferase activity mRNA (nucleoside-2'-O-)-methyltransferase activity structural molecule activity ATP binding methyltransferase activity transferase activity nucleotidyltransferase activity hydrolase activity nucleoside-triphosphatase activity
3m8uA heme-binding protein a	[pdb]	1.75 0.0012	297^LYS 299^PRO 450^GLY 456^ARG 294^ASN 420^GLY	0.0.0.0	transport		transporter activity
3phaA alpha-glucosidase	[pdb]	1.77 0.00125	433^LYS 436^PRO 64^GLY 63^ARG 61^ASN 59^GLY		carbohydrate metabolic process		catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds
1ud1C glycinin g1	[pdb]	1.78 0.00126	247^LYS 248^PRO 77^GLY 118^ARG 116^ASN 79^GLY	0.0.0.0			nutrient reservoir activity
3blvA isocitrate dehydrogenase [nad] subunit 1 isocitrate dehydrogenase [nad] subunit 2	[pdb]	1.8 0.0013	158^LYS 157^ILE 240^SER 129^VAL 131^LEU 134^ILE	0.0.0.0	tricarboxylic acid cycle isocitrate metabolic process glutamate biosynthetic process oxidation-reduction process tricarboxylic acid cycle isocitrate metabolic process glutamate biosynthetic process oxidation-reduction process	mitochondrion mitochondrial matrix mitochondrial isocitrate dehydrogenase complex (NAD+) mitochondrion mitochondrial matrix mitochondrial isocitrate dehydrogenase complex (NAD+) mitochondrial nucleoid	magnesium ion binding RNA binding isocitrate dehydrogenase (NAD+) activity protein binding oxidoreductase activity oxidoreductase activity acting on the CH-OH group of donors NAD or NADP as acceptor metal ion binding NAD binding magnesium ion binding RNA binding isocitrate dehydrogenase (NAD+) activity protein binding oxidoreductase activity oxidoreductase activity
1wfiA nuclear distribution gene c homolog	[pdb]	1.8 0.00132	106^LYS 109^PRO 1^GLY 11^ARG 9^ASN 7^GLY	0.0.0.0	cell cycle mitosis nuclear migration response to peptide hormone stimulus cell division	nucleus cytoplasm Golgi apparatus cytoskeleton microtubule	protein binding
1po0A iron(iii) dicitrate transport protein fecaprecursor	[pdb]	1.81 0.00135	353^LYS 348^PRO 407^GLY 390^ARG 355^ASN 86^GLY	0.0.0.0	transport ion transport iron ion transport siderophore transport	plasma membrane cell outer membrane membrane integral to membrane outer membrane	receptor activity transporter activity iron ion binding siderophore transmembrane transporter activity
2h9uA dna/rna-binding protein alba 2	[pdb]	1.88 0.00161	14^LYS 15^PRO 41^GLY 42^ARG 43^ASN 12^GLY	0.0.0.0		cytoplasm	nucleic acid binding DNA binding RNA binding
1zkmB adenylyltransferase thif	[pdb]	1.9 0.00171	83^LYS 82^PRO 191^GLY 70^ARG 67^ASN 37^GLY	0.0.0.0	metabolic process thiamine biosynthetic process		nucleotide binding catalytic activity binding ATP binding transferase activity nucleotidyltransferase activity metal ion binding
2j9pA penicillin-binding protein	[pdb]	1.92 0.00183	297^LYS 294^PRO 406^GLY 409^ARG 379^ASN 392^GLY	3.4.16.4	proteolysis cellular cell wall organization cell cycle regulation of cell shape peptidoglycan biosynthetic process cell division	extracellular region	serine-type carboxypeptidase activity serine-type D-Ala-D-Ala carboxypeptidase activity hydrolase activity
2uxyA aliphatic amidase	[pdb]	1.93 0.00192	46^LYS 50^PRO 126^GLY 92^ARG 95^ASN 98^GLY	3.5.1.4	nitrogen compound metabolic process		amidase activity hydrolase activity hydrolase activity
1ehaA glycosyltrehalose trehalohydrolase	[pdb]	1.93 0.00197	384^LYS 424^PRO 443^GLY 444^ARG 381^ASN 449^GLY	0.0.0.0	carbohydrate metabolic process trehalose biosynthetic process metabolic process	cytoplasm	catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds hydrolase activity hydrolase activity acting on glycosyl bonds
2qmrA transportin-1	[pdb]	1.94 0.00197	189^LYS 188^PRO 111^GLY 107^ARG 143^ASN 150^GLY	0.0.0.0	protein import into nucleus translocation transport intracellular protein transport protein transport	nucleus cytoplasm	binding protein binding nuclear localization sequence binding protein transporter activity
2z83A helicase/nucleoside triphosphatase	[pdb]	1.94 0.00197	399^LYS 396^PRO 463^GLY 461^ARG 417^ASN 419^GLY	2.7.7.48, 3.4.21.91	transcription RNA-dependent viral reproduction RNA metabolic process viral infectious cycle viral genome replication methylation transcription RNA-dependent viral reproduction RNA metabolic process viral infectious cycle viral genome replication evasion by virus of host immune response	membrane integral to membrane virion viral capsid viral envelope host cell membrane virion part membrane integral to membrane virion viral nucleocapsid viral capsid viral envelope host cell membrane virion part	nucleotide binding nucleic acid binding RNA binding RNA helicase activity double-stranded RNA binding catalytic activity RNA-directed RNA polymerase activity serine-type endopeptidase activity helicase activity structural molecule activity ATP binding methyltransferase activity hydrolase activity nucleotide binding nucleic acid binding RNA binding RNA helicase activity double-stranded RNA binding catalytic activity RNA-directed RNA polymerase activity serine-type endopeptidase activity helicase activity mRNA (guanine-N7-)-methyltransferase activity mRNA (nucleoside-2'-O-)-methyltransferase activity structural molecule activity ATP binding methyltransferase activity transferase activity nucleotidyltransferase activity hydrolase activity nucleoside-triphosphatase activity
2ho1A type 4 fimbrial biogenesis protein pilf	[pdb]	1.94 0.00202	236^LYS 240^PRO 215^HOH 210^ARG 208^ASN 232^GLY	0.0.0.0			binding
2y5eA limit dextrinase	[pdb]	1.95 0.00207	745^LYS 746^PRO 336^GLY 738^ARG 741^ASN 719^GLY	0.0.0.0	carbohydrate metabolic process		catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds cation binding
2wvaV pyruvate decarboxylase	[pdb]	1.95 0.00207	219^LYS 285^PRO 65^GLY 62^ARG 91^ASN 224^GLY	4.1.1.1			magnesium ion binding catalytic activity pyruvate decarboxylase activity transferase activity lyase activity carboxy-lyase activity thiamine pyrophosphate binding metal ion binding
2czgA phosphoribosylglycinamide formyl transferase	[pdb]	1.96 0.00213	378^LYS 379^PRO 26^GLY 50^ARG 53^ASN 28^GLY	0.0.0.0	purine nucleotide biosynthetic process purine ribonucleotide biosynthetic process		nucleotide binding magnesium ion binding catalytic activity ATP binding transferase activity hydroxymethyl- formyl- and related transferase activity
1wflA zinc finger protein 216	[pdb]	1.96 0.00213	24^LYS 23^PRO 50^GLY 53^ARG 46^ASN 39^GLY	0.0.0.0	in utero embryonic development vasculature development respiratory system process fibroblast migration platelet-derived growth factor receptor signaling pathway skeletal system morphogenesis smooth muscle tissue development face development		DNA binding zinc ion binding metal ion binding
1bpwA protein (aldehyde dehydrogenase)	[pdb]	1.97 0.00225	342^LYS 343^PRO 13^GLY 47^ARG 378^ASN 338^GLY	1.2.1.8, 1.2.1.3	metabolic process oxidation-reduction process	cytoplasm	aldehyde dehydrogenase (NAD) activity betaine-aldehyde dehydrogenase activity oxidoreductase activity
3igzB cofactor-independent phosphoglycerate mutase	[pdb]	1.97 0.00231	333^LYS 332^PRO 371^GLY 369^ARG 368^ASN 319^GLY	0.0.0.0	glucose catabolic process metabolic process	cytoplasm	catalytic activity phosphoglycerate mutase activity isomerase activity manganese ion binding metal ion binding
1t3qE quinoline 2-oxidoreductase medium subunit quinoline 2-oxidoreductase small subunit quinoline 2-oxidoreductase large subunit	[pdb]	1.98 0.00238	364^LYS 366^PRO 153^LYS 156^TYR 164^GLU 146^VAL	0.0.0.0	oxidation-reduction process oxidation-reduction process oxidation-reduction process		electron carrier activity oxidoreductase activity metal ion binding iron-sulfur cluster binding 2 iron 2 sulfur cluster binding oxidoreductase activity catalytic activity oxidoreductase activity
3qn3B enolase	[pdb]	1.98 0.00238	332^LYS 333^PRO 320^GLY 318^ARG 313^ASN 306^GLY		glycolysis	phosphopyruvate hydratase complex extracellular region cytoplasm cell surface	magnesium ion binding phosphopyruvate hydratase activity lyase activity metal ion binding
3izrC 60s ribosomal protein l4 (l4p) 60s ribosomal protein l17 (l22p) 60s ribosomal protein l13 (l13e) 60s ribosomal protein l7 (l30p) 60s ribosomal protein l37 (l37e) 60s ribosomal protein l26 (l24p) 60s ribosomal protein l32 (l32e) 60s ribosomal protein l28 (l28e) 60s ribosomal protein l30 (l30e) 60s acidic ribosomal protein p11 - p1 (l12p) 60s ribosomal protein l41 (l41e) 60s ribosomal protein l22 (l22e) 60s ribosomal protein l35 (l29p) 60s ribosomal protein l2 (l2p) 60s ribosomal protein l18 (l18e) 60s ribosomal protein l15 (l15e) 60s ribosomal protein l21 (l21e) 60s ribosomal protein l9 (l6p) 60s ribosomal protein l38 (l38e) 60s ribosomal protein l19 (l19e) 60s ribosomal protein l27 (l27e) 60s ribosomal protein l24 (l24e) 60s ribosomal protein l3 (l3p) 60s ribosomal protein l11 (l5p) 60s ribosomal protein l23a (l23p) 60s ribosomal protein l39 (l39e) 60s ribosomal protein l31 (l31e) 60s ribosomal protein l29 (l29e) 60s acidic ribosomal protein p21 - p2 (l12p) 60s ribosomal protein l7a (l7ae) 60s ribosomal protein l12 (l11p) 60s ribosomal protein l10 (l10e) 60s ribosomal protein l40 (l40e) 60s ribosomal protein l43 (l37ae) 60s ribosomal protein l34 (l34e) 60s ribosomal protein l5 (l18p) 60s ribosomal protein l14 (l14e) 60s ribosomal protein l13a (l13p) 60s ribosomal protein l6 (l6e) 60s ribosomal protein l36 (l36e) 60s ribosomal protein l27a (l15p) 60s ribosomal protein l23 (l14p) 60s ribosomal protein l42 (l44e) unknown 60s ribosomal protein xl 60s ribosomal protein l18a (l18ae) 60s acidic ribosomal protein p0 (l10p) 60s ribosomal protein l35a (l35ae) unknown 60s ribosomal protein xl3 60s ribosomal protein l1 (l1p)	[pdb]	1.98 0.00238	225^ALA 335^PRO 231^GLY 235^ALA 273^ASN 228^ASN	0.0.0.0	ribosome biogenesis translational elongation ribosome biogenesis translation translation translation translation translation translation translation translation translation translational elongation translation translation translation translation translation translation translation RNA processing translation translation translation translation translation translation translation translation translation translation translation translation translation translation translational elongation translation translation translation translation translation translation translation translation translation translation translation translation	ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex ribosome ribonucleoprotein complex intracellular ribosome intracellular ribosome intracellular ribosome intracellular ribosome large ribosomal subunit intracellular ribosome intracellular ribosome ribonucleoprotein complex intracellular ribosome intracellular ribosome large ribosomal subunit ribonucleoprotein complex intracellular ribosome intracellular ribosome intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome large ribosomal subunit ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome intracellular ribosome ribonucleoprotein complex intracellular ribosome intracellular ribosome ribonucleoprotein complex intracellular ribosome intracellular ribosome intracellular ribosome large ribosomal subunit ribonucleoprotein complex intracellular ribosome intracellular ribosome ribonucleoprotein complex intracellular ribosome intracellular ribosome intracellular ribosome intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome intracellular ribosome ribonucleoprotein complex ribosome intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex intracellular ribosome	structural constituent of ribosome structural constituent of ribosome rRNA binding structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome transcription regulator activity structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome RNA binding structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome metal ion binding structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome RNA binding structural constituent of ribosome rRNA binding metal ion binding structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome RNA binding structural constituent of ribosome 5S rRNA binding rRNA binding structural constituent of ribosome nucleotide binding RNA binding structural constituent of ribosome structural constituent of ribosome
1jqvA dihydroorotate dehydrogenase a	[pdb]	1.98 0.00244	225^LYS 226^PRO 264^GLY 233^ARG 231^ASN 247^GLY	1.3.3.1	'de novo' pyrimidine base biosynthetic process pyrimidine nucleotide biosynthetic process UMP biosynthetic process metabolic process oxidation-reduction process 'de novo' pyrimidine base biosynthetic process pyrimidine nucleotide biosynthetic process UMP biosynthetic process metabolic process oxidation-reduction process	cytoplasm cytoplasm	catalytic activity dihydroorotate dehydrogenase activity dihydroorotate oxidase activity oxidoreductase activity catalytic activity dihydroorotate dehydrogenase activity dihydroorotate oxidase activity oxidoreductase activity
1yb5A quinone oxidoreductase	[pdb]	1.99 0.00244	296^LYS 297^PRO 173^GLY 170^ARG 192^ASN 293^GLY	1.6.5.5	visual perception metabolic process xenobiotic catabolic process protein homotetramerization oxidation-reduction process	soluble fraction cytoplasm cytosol	RNA binding mRNA 3'-UTR binding catalytic activity NADPH:quinone reductase activity binding zinc ion binding oxidoreductase activity NADPH binding NADH binding
3bohB cadmium-specific carbonic anhydrase	[pdb]	1.99 0.00244	199^LYS 198^PRO 81^GLY 80^ARG 79^ASN 130^GLY	0.0.0.0
1qkiH glucose-6-phosphate 1-dehydrogenase	[pdb]	1.99 0.00244	366^LYS 396^PRO 488^GLY 487^ARG 363^ASN 359^GLY	1.1.1.49	cytokine production carbohydrate metabolic process glucose metabolic process pentose-phosphate shunt lipid metabolic process cholesterol biosynthetic process NADPH regeneration glutathione metabolic process metabolic process pentose-phosphate shunt oxidative branch negative regulation of protein glutathionylation pentose biosynthetic process cellular response to oxidative stress erythrocyte maturation ribose phosphate biosynthetic process glucose 6-phosphate metabolic process	cytoplasm centrosome cytosol internal side of plasma membrane intracellular membrane-bounded organelle	catalytic activity glucose-6-phosphate dehydrogenase activity binding glucose binding oxidoreductase activity protein homodimerization activity NADP binding
3m2vC methyl-coenzyme m reductase i subunit gamma methyl-coenzyme m reductase i subunit beta methyl-coenzyme m reductase i subunit alpha	[pdb]	1.99 0.00251	188^LYS 198^PRO 152^GLY 151^ARG 189^ASN 192^GLY	2.8.4.1	methanogenesis methanogenesis methanogenesis		transferase activity metal ion binding coenzyme-B sulfoethylthiotransferase activity transferase activity coenzyme-B sulfoethylthiotransferase activity transferase activity coenzyme-B sulfoethylthiotransferase activity
3ch8A c-terminal octatpeptide from protein arvcf fusion protein pdz-fibronectin	[pdb]	1.99 0.00251	46^LYS 43^PRO 13^VAL 15^HOH 17^HOH 25^GLY	0.0.0.0	cell cycle cell adhesion signal transduction epidermal growth factor receptor signaling pathway integrin-mediated signaling pathway cell growth intermediate filament cytoskeleton organization basal protein localization establishment or maintenance of epithelial cell apical/basal polarity	basement membrane nucleus cytoplasm basal plasma membrane cell junction hemidesmosome	ErbB-2 class receptor binding integrin binding structural constituent of cytoskeleton protein binding
2wjsA laminin subunit alpha-2	[pdb]	2 0.00259	2529^LYS 2530^PRO 2617^GLY 2553^ARG 2554^ASN 2678^GLY	0.0.0.0	cell adhesion regulation of cell adhesion regulation of cell migration positive regulation of synaptic transmission cholinergic	extracellular region proteinaceous extracellular matrix basement membrane basal lamina laminin-1 complex extracellular matrix sarcolemma	receptor binding
2gw2A peptidyl-prolyl cis-trans isomerase g	[pdb]	2 0.00259	164^LYS 165^PRO 87^GLY 85^ARG 83^ASN 76^GLY	5.2.1.8	protein folding RNA splicing	nucleus nucleoplasm nuclear matrix nuclear speck	peptidyl-prolyl cis-trans isomerase activity cyclosporin A binding isomerase activity peptide binding
1ul1Z flap endonuclease-1 proliferating cell nuclear antigen	[pdb]	2 0.00259	80^LYS 81^CYS 334^GLY 332^ARG 77^LYS 28^TRP	0.0.0.0	DNA replication regulation of DNA replication DNA repair base-excision repair gap-filling nucleotide-excision repair DNA gap filling mismatch repair intracellular protein transport heart development cell proliferation translesion synthesis response to lipid response to cadmium ion phosphatidylinositol-mediated signaling DNA replication DNA repair double-strand break repair UV protection	cyclin-dependent protein kinase holoenzyme complex nucleus nuclear lamina nucleoplasm replication fork DNA replication factor C complex nuclear replication fork PCNA complex PCNA-p21 complex nucleus mitochondrion	purine-specific mismatch base pair DNA N-glycosylase activity DNA binding protein binding DNA polymerase processivity factor activity dinucleotide insertion or deletion binding MutLalpha complex binding magnesium ion binding DNA binding damaged DNA binding double-stranded DNA binding catalytic activity nuclease activity endonuclease activity ribonuclease H activity exonuclease activity protein binding double-stranded DNA specific exodeoxyribonuclease activity 5'-3' exonuclease activity hydrolase activity 5'-flap endonuclease activity manganese ion binding metal ion binding flap endonuclease activity
3ideD capsid protein vp2	[pdb]	2.01 0.00266	172^LYS 173^PRO 128^GLY 348^ARG 342^ASN 169^GLY			virion host cell cytoplasm	structural molecule activity peptidase activity serine-type peptidase activity hydrolase activity metal ion binding
3hgsA 12-oxophytodienoate reductase 3	[pdb]	2.01 0.00274	131^LYS 132^PRO 209^GLY 203^ARG 201^ASN 199^GLY	1.3.1.42	fatty acid biosynthetic process metabolic process lipid biosynthetic process oxylipin biosynthetic process oxidation-reduction process	peroxisome	catalytic activity FMN binding oxidoreductase activity 12-oxophytodienoate reductase activity
1xa0A putative nadph dependent oxidoreductases	[pdb]	2.01 0.00274	312^LYS 308^PRO 160^GLY 322^ARG 43^ASN 317^GLY	0.0.0.0
1iokD chaperonin 60	[pdb]	2.01 0.00282	34^LYS 33^PRO 462^GLY 452^ARG 457^ASN 459^GLY	0.0.0.0	protein folding cellular protein metabolic process	cytoplasm	nucleotide binding protein binding ATP binding
1ofdB ferredoxin-dependent glutamate synthase 2	[pdb]	2.02 0.00282	1476^LYS 1475^PRO 1380^GLY 1378^ARG 1376^ASN 1414^GLY	1.4.7.1	glutamate biosynthetic process glutamine metabolic process nitrogen compound metabolic process metabolic process cellular amino acid biosynthetic process oxidation-reduction process		catalytic activity protein binding glutamate synthase activity glutamate synthase (ferredoxin) activity oxidoreductase activity metal ion binding iron-sulfur cluster binding 3 iron
1tdhA nei endonuclease viii-like 1	[pdb]	2.02 0.00291	54^LYS 2^PRO 134^GLY 169^ARG 172^ASN 53^GLY	4.2.99.18	DNA repair base-excision repair nucleotide-excision repair response to DNA damage stimulus response to oxidative stress metabolic process negative regulation of nuclease activity	nucleus cytoplasm	nucleic acid binding DNA binding damaged DNA binding catalytic activity DNA-(apurinic or apyrimidinic site) lyase activity protein C-terminus binding zinc ion binding hydrolase activity hydrolase activity acting on glycosyl bonds hydrolase activity hydrolyzing N-glycosyl compounds
2r6iA uncharacterized protein atu1473	[pdb]	2.02 0.00291	62^LYS 63^PRO 0^GLY 95^ARG 98^ASN 103^GLY	0.0.0.0	proton-transporting ATP synthase complex assembly		protein binding
2ot8A transportin-1 heterogeneous nuclear ribonucleoprotein m	[pdb]	2.02 0.00291	189^LYS 188^PRO 111^GLY 107^ARG 143^ASN 150^GLY	0.0.0.0	protein import into nucleus translocation transport intracellular protein transport protein transport interspecies interaction between organisms alternative nuclear mRNA splicing via spliceosome nuclear mRNA splicing	nucleus cytoplasm nucleus nucleoplasm spliceosomal complex nucleolus integral to plasma membrane nuclear matrix ribonucleoprotein complex paraspeckles	binding protein binding nuclear localization sequence binding protein transporter activity nucleotide binding nucleic acid binding RNA binding protein binding protein domain specific binding
3gweB 3-oxoacyl-(acyl-carrier-protein) synthase iii	[pdb]	2.03 0.00291	40^LYS 37^PRO 300^GLY 50^ARG 26^ASN 46^GLY	0.0.0.0	fatty acid biosynthetic process metabolic process lipid biosynthetic process		catalytic activity 3-oxoacyl-[acyl-carrier-protein] synthase activity transferase activity
1y7eA probable m18-family aminopeptidase 1	[pdb]	2.03 0.00299	276^LYS 274^PRO 420^GLY 422^ARG 90^ASN 88^GLY	0.0.0.0	proteolysis proteolysis	vacuole vacuole	aminopeptidase activity peptidase activity metallopeptidase activity zinc ion binding hydrolase activity metal ion binding aminopeptidase activity peptidase activity metallopeptidase activity zinc ion binding hydrolase activity metal ion binding
2vzeA acyl-coenzyme a synthetase acsm2a, mitochondrial	[pdb]	2.03 0.003	43^LYS 41^PRO 130^GLY 128^ARG 45^ASN 211^GLY	6.2.1.2	lipid metabolic process fatty acid metabolic process metabolic process	mitochondrion mitochondrial matrix	nucleotide binding catalytic activity ATP binding ligase activity metal ion binding butyrate-CoA ligase activity
2ct6A sh3 domain-binding glutamic acid-rich-likeprotein 2	[pdb]	2.03 0.003	64^LYS 62^PRO 79^GLY 81^ARG 59^ASN 84^GLY			nucleus	SH3 domain binding
1dimA sialidase	[pdb]	2.04 0.00309	333^LYS 332^PRO 279^GLY 276^ARG 302^ASN 341^GLY	3.2.1.18	metabolic process pathogenesis		exo-alpha-sialidase activity hydrolase activity hydrolase activity
2ph4B zhaoermiatoxin	[pdb]	2.05 0.00328	38^LYS 37^PRO 32^GLY 33^ARG 28^ASN 26^GLY	0.0.0.0	phospholipid metabolic process pathogenesis lipid catabolic process	extracellular region	phospholipase A2 activity calcium ion binding
2qbwA polypeptide pdz-fibronectin fusion protein	[pdb]	2.05 0.00328	46^LYS 43^PRO 13^VAL 15^HOH 17^HOH 25^HOH	0.0.0.0	cell cycle cell adhesion signal transduction epidermal growth factor receptor signaling pathway integrin-mediated signaling pathway cell growth intermediate filament cytoskeleton organization basal protein localization establishment or maintenance of epithelial cell apical/basal polarity	basement membrane nucleus cytoplasm basal plasma membrane cell junction hemidesmosome	ErbB-2 class receptor binding integrin binding structural constituent of cytoskeleton protein binding
1w4vF thioredoxin, mitochondrial	[pdb]	2.05 0.00328	81^LYS 21^PRO 8^GLY 14^ARG 17^ASN 83^GLY	0.0.0.0	response to hypoxia glycerol ether metabolic process transport response to oxidative stress response to nutrient response to hormone stimulus response to glucose stimulus response to organic cyclic compound electron transport chain cellular response to nutrient levels response to drug cell redox homeostasis response to axon injury	mitochondrion	protein binding peptide-methionine-(S)-S-oxide reductase activity electron carrier activity protein disulfide oxidoreductase activity protein complex binding peptide-methionine (R)-S-oxide reductase activity
1f76B dihydroorotate dehydrogenase	[pdb]	2.05 0.00328	142^LYS 147^PRO 119^GLY 90^ARG 143^ASN 141^GLY	1.3.3.1	'de novo' pyrimidine base biosynthetic process pyrimidine nucleotide biosynthetic process UMP biosynthetic process metabolic process oxidation-reduction process	plasma membrane membrane	catalytic activity dihydroorotate dehydrogenase activity dihydroorotate oxidase activity oxidoreductase activity
3dasA putative oxidoreductase	[pdb]	2.05 0.00337	136^LYS 135^PRO 84^GLY 144^ARG 107^ASN 80^GLY	0.0.0.0			catalytic activity
1vouD 23s ribosomal rna 50s ribosomal protein l32 50s ribosomal protein l9 50s ribosomal protein l3 50s ribosomal protein l2 50s ribosomal protein l6 50s ribosomal protein l5 50s ribosomal protein l4 50s ribosomal protein l19 50s ribosomal protein l18 50s ribosomal protein l31 50s ribosomal protein l16 50s ribosomal protein l33 50s ribosomal protein l14 50s ribosomal protein l13 50s ribosomal protein l34 50s ribosomal protein l11 50s ribosomal protein l36 general stress protein ctc 50s ribosomal protein l17 50s ribosomal protein l30 50s ribosomal protein l15 5s ribosomal rna 50s ribosomal protein l35 50s ribosomal protein l29 50s ribosomal protein l22 50s ribosomal protein l23 50s ribosomal protein l20 50s ribosomal protein l21 50s ribosomal protein l27 50s ribosomal protein l24 50s ribosomal protein l1p	[pdb]	2.05 0.00337	218^LYS 219^PRO 42^LYS 43^LYS 44^GLY 57^GLN	0.0.0.0	translation translation	intracellular ribosome ribonucleoprotein complex intracellular ribosome ribonucleoprotein complex	RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding metal ion binding
2f2lA peptidoglycan-recognition protein-lc isoform lca peptidoglycan recognition protein-lc isoform lcx	[pdb]	2.06 0.00347	484^GLU 376^VAL 431^GLY 432^ILE 435^ILE 479^THR	0.0.0.0	peptidoglycan catabolic process innate immune response phagocytosis immune response positive regulation of antibacterial peptide biosynthetic process peptidoglycan catabolic process response to bacterium antimicrobial humoral response antibacterial humoral response innate immune response defense response to Gram-negative bacterium defense response to virus	integral to plasma membrane membrane integral to membrane membrane integral to membrane	protein binding N-acetylmuramoyl-L-alanine amidase activity peptidoglycan binding protein binding pattern recognition receptor activity N-acetylmuramoyl-L-alanine amidase activity peptidoglycan receptor activity peptidoglycan binding protein dimerization activity Gram-negative bacterial cell surface binding
3dmcB ntf2-like protein	[pdb]	2.06 0.00347	105^LYS 103^PRO 127^GLY 107^ARG 133^ASN 130^GLY	0.0.0.0
3boeA cadmium-specific carbonic anhydrase	[pdb]	2.06 0.00347	409^LYS 408^PRO 291^GLY 290^ARG 289^ASN 340^GLY	0.0.0.0
2wxqA phosphatidylinositol-4,5-bisphosphate 3-kinasecatalytic subunit delta isoform	[pdb]	2.06 0.00347	642^LYS 168^PRO 635^GLY 636^ARG 640^ASN 644^GLY	2.7.1.153	B cell homeostasis signal transduction cell surface receptor linked signaling pathway B cell activation phosphatidylinositol phosphorylation phosphatidylinositol-mediated signaling B cell homeostasis signal transduction cell surface receptor linked signaling pathway B cell activation phosphatidylinositol phosphorylation phosphatidylinositol-mediated signaling	phosphatidylinositol 3-kinase complex phosphatidylinositol 3-kinase complex	inositol or phosphatidylinositol kinase activity binding kinase activity 1-phosphatidylinositol-3-kinase activity transferase activity phosphotransferase activity alcohol group as acceptor phosphatidylinositol-4,5-bisphosphate 3-kinase activity nucleotide binding inositol or phosphatidylinositol kinase activity binding ATP binding kinase activity 1-phosphatidylinositol-3-kinase activity transferase activity phosphotransferase activity
2vy0A endo-beta-1,3-glucanase	[pdb]	2.06 0.00347	256^LYS 257^PRO 164^GLY 161^ARG 159^ASN 169^GLY	0.0.0.0	carbohydrate metabolic process		hydrolase activity
2yybB hypothetical protein ttha1606	[pdb]	2.07 0.00358	129^LYS 123^PRO 117^GLY 114^ARG 109^ASN 130^GLY	0.0.0.0
2i3yA epididymal secretory glutathione peroxidase	[pdb]	2.07 0.00368	106^LYS 109^PRO 164^GLY 180^ARG 182^ASN 105^GLY	1.11.1.9	lipid metabolic process response to oxidative stress oxidation-reduction process	extracellular region	peroxidase activity glutathione peroxidase activity oxidoreductase activity
1yzcA edesigned apo-cytochrome b562	[pdb]	2.08 0.00368	59^LYS 56^PRO 98^GLY 99^ARG 102^ASN 64^GLY	0.0.0.0	electron transport chain	periplasmic space	iron ion binding electron carrier activity heme binding
2ywoA probable thiol-disulfide isomerase/thioredoxin	[pdb]	2.08 0.00379	140^LYS 142^PRO 133^GLY 134^ARG 136^ASN 172^GLY	0.0.0.0	cell redox homeostasis		antioxidant activity oxidoreductase activity isomerase activity
1yq4A succinate dehydrogenase ip subunit succinate dehydrogenase cytochrome b, smallsubunit succinate dehydrogenase cytochrome b, largesubunit succinate dehydrogenase flavoprotein subunit	[pdb]	2.08 0.00379	85^TYR 616^PRO 410^GLY 408^ARG 407^ASN 132^LEU	1.3.5.1	tricarboxylic acid cycle succinate metabolic process transport nervous system development electron transport chain respiratory electron transport chain oxidation-reduction process tricarboxylic acid cycle transport electron transport chain tricarboxylic acid cycle transport electron transport chain oxidation-reduction process	mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex II membrane mitochondrion mitochondrial envelope mitochondrial inner membrane mitochondrial respiratory chain complex II membrane integral to membrane mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex II membrane	succinate dehydrogenase activity protein binding succinate dehydrogenase (ubiquinone) activity electron carrier activity oxidoreductase activity oxidoreductase activity acting on the CH-CH group of donors flavin adenine dinucleotide binding succinate dehydrogenase activity iron ion binding heme binding metal ion binding ubiquinone binding protein binding succinate dehydrogenase (ubiquinone) activity electron carrier activity oxidoreductase activity metal ion binding ubiquinone binding iron-sulfur cluster binding 2 iron 2 sulfur cluster binding
2y4mA mannosylglycerate synthase	[pdb]	2.08 0.0039	76^LYS 7^PRO 70^GLY 68^ARG 81^ASN 77^GLY
3c2uA xylosidase/arabinosidase	[pdb]	2.08 0.0039	496^LYS 493^PRO 506^GLY 503^ARG 419^ASN 510^GLY	0.0.0.0	carbohydrate metabolic process		hydrolase activity
3fecA glutamate carboxypeptidase iii	[pdb]	2.09 0.0039	310^LYS 304^PRO 196^GLY 171^ARG 168^ASN 311^GLY	3.4.17.21	proteolysis neurotransmitter catabolic process	membrane integral to membrane	catalytic activity carboxypeptidase activity peptidase activity serine-type peptidase activity metallopeptidase activity dipeptidyl-peptidase activity hydrolase activity dipeptidase activity metal ion binding
2q3oA 12-oxophytodienoate reductase 3	[pdb]	2.09 0.00402	131^LYS 132^PRO 210^GLY 204^ARG 202^ASN 200^GLY	1.3.1.42	fatty acid biosynthetic process metabolic process lipid biosynthetic process response to fungus jasmonic acid biosynthetic process response to ozone oxylipin biosynthetic process oxidation-reduction process	peroxisome	catalytic activity FMN binding oxidoreductase activity 12-oxophytodienoate reductase activity
1n8wA probable malate synthase g	[pdb]	2.09 0.00402	296^LYS 384^PRO 391^GLY 389^ARG 387^ASN 375^GLY	2.3.3.9	glyoxylate cycle tricarboxylic acid cycle coenzyme A metabolic process	extracellular region cell wall cytoplasm cytosol plasma membrane	magnesium ion binding catalytic activity malate synthase activity protein binding transferase activity manganese ion binding
3al0B glutamyl-trna(gln) amidotransferase subunit a aspartyl/glutamyl-trna(asn/gln) amidotransferase subunit b trnagln glutamyl-trna(gln) amidotransferase subunit c, glutamyl-trna synthetase 2	[pdb]	2.09 0.00402	20^U 26^G 129^VAL 150^LEU 149^ALA 152^ASN	0.0.0.0	translation regulation of translational fidelity translation translation translation tRNA aminoacylation for protein translation glutamyl-tRNA aminoacylation tRNA aminoacylation	cytoplasm	nucleotide binding ATP binding ligase activity nucleotide binding ATP binding ligase activity carbon-nitrogen ligase activity with glutamine as amido-N-donor nucleotide binding ATP binding ligase activity carbon-nitrogen ligase activity with glutamine as amido-N-donor nucleotide binding aminoacyl-tRNA ligase activity glutamate-tRNA ligase activity ATP binding
3f7sA uncharacterized ntf2-like protein	[pdb]	2.09 0.00402	140^LYS 141^PRO 93^GLY 91^ARG 90^ASN 102^GLY	0.0.0.0	protein phosphorylation		calmodulin-dependent protein kinase activity calmodulin binding
1a65A laccase	[pdb]	2.09 0.00402	264^LYS 262^PRO 179^GLY 175^ARG 278^ASN 268^GLY	0.0.0.0	oxidation-reduction process		copper ion binding laccase activity oxidoreductase activity metal ion binding
3i5oB oligopeptide abc transporter, periplasmicoligopeptide-binding protein	[pdb]	2.1 0.00414	273^LYS 274^PRO 459^GLY 463^ARG 270^ASN 419^GLY	0.0.0.0	transport		transporter activity
1fj2B protein (acyl protein thioesterase 1)	[pdb]	2.1 0.00414	185^LYS 190^PRO 153^GLY 157^ARG 189^ASN 150^GLY	0.0.0.0	lipid metabolic process fatty acid metabolic process	cytoplasm mitochondrion	lysophospholipase activity hydrolase activity
2e9fA argininosuccinate lyase	[pdb]	2.1 0.00426	222^LYS 224^PRO 124^GLY 119^ARG 194^ASN 220^GLY	4.3.2.1	arginine biosynthetic process cellular amino acid biosynthetic process arginine biosynthetic process via ornithine	cytoplasm	catalytic activity argininosuccinate lyase activity lyase activity
2e55B uracil phosphoribosyltransferase	[pdb]	2.1 0.00426	11^LYS 8^PRO 194^GLY 18^ARG 15^ASN 179^GLY	2.4.2.9	uracil salvage nucleoside metabolic process		nucleotide binding uracil phosphoribosyltransferase activity GTP binding transferase activity transferase activity
2w0jA serine/threonine-protein kinase chk2	[pdb]	2.1 0.00426	472^LYS 471^PRO 342^GLY 406^ARG 405^ASN 403^GLY	2.7.11.1	DNA damage checkpoint protein phosphorylation response to DNA damage stimulus cell cycle DNA damage response signal transduction resulting in induction of apoptosis senescence	nucleus PML body chromosome	nucleotide binding protein kinase activity protein serine/threonine kinase activity protein binding ATP binding kinase activity transferase activity metal ion binding
2jwnA embryonic polyadenylate-binding protein 2-b	[pdb]	2.11 0.00438	78^LYS 77^PRO 104^GLY 105^ARG 43^ASN 47^GLY	0.0.0.0	biological_process	cytoplasm	nucleotide binding nucleic acid binding RNA binding poly(A) RNA binding
3bs0B todx	[pdb]	2.11 0.00438	242^LYS 278^PRO 140^GLY 222^ARG 240^ASN 220^GLY	0.0.0.0	transport transport	membrane membrane	transporter activity transporter activity
2y8jB carbohydrate binding family 6	[pdb]	2.11 0.00438	742^LYS 741^PRO 790^GLY 792^ARG 793^ASN 745^GLY		polysaccharide catabolic process carbohydrate metabolic process		catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds carbohydrate binding
2avwB igg-degrading protease	[pdb]	2.11 0.00451	201^LYS 203^PRO 215^GLY 214^ARG 182^ASN 199^GLY	0.0.0.0			peptidase activity
2h3lB lap2 protein	[pdb]	2.12 0.00451	1374^LYS 1371^PRO 1342^GLY 1343^ARG 1345^ASN 1353^GLY	0.0.0.0	cell cycle cell adhesion signal transduction epidermal growth factor receptor signaling pathway integrin-mediated signaling pathway cell growth intermediate filament cytoskeleton organization basal protein localization establishment or maintenance of epithelial cell apical/basal polarity	basement membrane nucleus cytoplasm basal plasma membrane cell junction hemidesmosome	ErbB-2 class receptor binding integrin binding structural constituent of cytoskeleton protein binding
3hpeA conserved hypothetical secreted protein	[pdb]	2.12 0.00451	121^LYS 122^PRO 159^GLY 153^ARG 152^ASN 157^GLY	0.0.0.0
3fa2A brca1-associated ring domain protein 1	[pdb]	2.12 0.00463	670^LYS 669^PRO 656^GLY 659^ARG 663^ASN 627^GLY	0.0.0.0	tissue homeostasis DNA repair response to DNA damage stimulus cell cycle arrest spermatogenesis protein ubiquitination negative regulation of mRNA 3'-end processing regulation of phosphorylation positive regulation of apoptosis negative regulation of apoptosis positive regulation of protein catabolic process negative regulation of protein export from nucleus protein K6-linked ubiquitination	ubiquitin ligase complex intracellular nucleus cytoplasm BRCA1-BARD1 complex BRCA1-A complex	RNA binding ubiquitin-protein ligase activity protein binding zinc ion binding ligase activity kinase binding protein homodimerization activity metal ion binding protein heterodimerization activity
2x8cB thioredoxin glutathione reductase	[pdb]	2.12 0.00464	438^LYS 439^PRO 413^GLY 414^ARG 435^ASN 437^GLY	0.0.0.0	cell redox homeostasis oxidation-reduction process	cytoplasm	thioredoxin-disulfide reductase activity electron carrier activity protein disulfide oxidoreductase activity oxidoreductase activity oxidoreductase activity acting on a sulfur group of donors NAD or NADP as acceptor
3icsA coenzyme a-disulfide reductase	[pdb]	2.13 0.00477	117^LYS 118^PRO 10^GLY 35^ARG 137^ASN 115^GLY	0.0.0.0	protein thiol-disulfide exchange cell redox homeostasis oxidation-reduction process	cytoplasm	oxidoreductase activity CoA-disulfide reductase activity flavin adenine dinucleotide binding NADP binding
2cdbB glucose dehydrogenase glucose 1-dehydrogenase,dhg-1	[pdb]	2.13 0.00477	310^LYS 311^PRO 113^GLY 90^ARG 307^ASN 102^GLY	0.0.0.0	metabolic process oxidation-reduction process		catalytic activity binding zinc ion binding oxidoreductase activity glucose 1-dehydrogenase activity
3afvA dyp	[pdb]	2.13 0.00477	311^LYS 314^PRO 102^GLY 368^ARG 373^ASN 395^GLY
3pm9A putative oxidoreductase	[pdb]	2.13 0.00477	345^LYS 342^PRO 379^GLY 381^ARG 396^ASN 349^GLY	0.0.0.0			catalytic activity oxidoreductase activity flavin adenine dinucleotide binding
1ua4A adp-dependent glucokinase	[pdb]	2.14 0.00504	433^LYS 432^PRO 111^GLY 109^ARG 377^ASN 437^GLY	2.7.1.147	carbohydrate metabolic process glucose metabolic process glycolysis	cytoplasm	magnesium ion binding kinase activity transferase activity phosphotransferase activity alcohol group as acceptor ADP-specific glucokinase activity
2gn2A threonine dehydratase catabolic	[pdb]	2.14 0.00504	157^LYS 156^PRO 23^GLY 20^ARG 64^ASN 161^GLY	4.3.1.19	cellular amino acid metabolic process metabolic process		catalytic activity L-threonine ammonia-lyase activity lyase activity pyridoxal phosphate binding
2v4jA sulfite reductase, dissimilatory-type subunitgamma sulfite reductase, dissimilatory-type subunitalpha sulfite reductase, dissimilatory-type subunitbeta	[pdb]	2.14 0.00504	213^ILE 211^PRO 165^ILE 172^ASP 170^PHE 168^GLU	1.8.99.3	oxidation-reduction process oxidation-reduction process oxidation-reduction process	cytoplasm	oxidoreductase activity hydrogensulfite reductase activity oxidoreductase activity hydrogensulfite reductase activity heme binding metal ion binding iron-sulfur cluster binding 4 iron 4 sulfur cluster binding electron carrier activity oxidoreductase activity hydrogensulfite reductase activity heme binding metal ion binding iron-sulfur cluster binding
1pe4A neurotoxin cn11	[pdb]	2.14 0.00504	12^LYS 5^PRO 63^GLY 66^ARG 9^ASN 58^GLY	0.0.0.0	defense response pathogenesis	extracellular region	ion channel inhibitor activity sodium channel inhibitor activity
2k46A mgc80075 protein	[pdb]	2.14 0.00504	31^LYS 33^PRO 45^GLY 65^ARG 15^ASN 18^GLY	0.0.0.0	carbohydrate metabolic process protein amino acid terminal N-glycosylation	endoplasmic reticulum endoplasmic reticulum membrane membrane integral to membrane	carbohydrate binding
1q20A sulfotransferase family, cytosolic, 2b, member 1isoform b	[pdb]	2.15 0.00518	70^LYS 69^PRO 279^GLY 150^ARG 148^ASN 276^GLY	2.8.2.2	sulfate assimilation lipid metabolic process steroid metabolic process	cytoplasm cytosol	alcohol sulfotransferase activity protein binding sulfotransferase activity transferase activity steroid sulfotransferase activity
3aflA oligo alginate lyase	[pdb]	2.15 0.00518	405^LYS 424^PRO 437^GLY 433^ARG 431^ASN 398^GLY	0.0.0.0			lyase activity
1rfeA hypothetical protein rv2991	[pdb]	2.15 0.00518	122^LYS 123^PRO 134^GLY 132^ARG 130^ASN 106^GLY	0.0.0.0			FMN binding
1tigA translation initiation factor 3	[pdb]	2.15 0.00533	155^LYS 154^PRO 124^GLY 159^ARG 160^ASN 133^GLY	0.0.0.0	translation translational initiation	cytoplasm	translation initiation factor activity
2wu5E succinate dehydrogenase hydrophobic membrane anchorprotein subunit succinate dehydrogenase iron-sulfur subunit succinate dehydrogenase cytochrome b556 subunit succinate dehydrogenase flavoprotein subunit	[pdb]	2.15 0.00533	74^ILE 583^PRO 401^GLY 399^ARG 398^ASN 121^SER	1.3.99.1	tricarboxylic acid cycle transport aerobic respiration electron transport chain oxidation-reduction process tricarboxylic acid cycle transport aerobic respiration electron transport chain oxidation-reduction process tricarboxylic acid cycle transport aerobic respiration cytochrome complex assembly electron transport chain tricarboxylic acid cycle transport aerobic respiration cytochrome complex assembly electron transport chain	plasma membrane membrane plasma membrane membrane plasma membrane succinate dehydrogenase complex plasma membrane membrane integral to membrane plasma membrane membrane integral to membrane	succinate dehydrogenase activity protein binding electron carrier activity oxidoreductase activity metal ion binding iron-sulfur cluster binding 2 iron 2 sulfur cluster binding 3 iron 4 sulfur cluster binding 4 iron 4 sulfur cluster binding succinate dehydrogenase activity protein binding electron carrier activity oxidoreductase activity oxidoreductase activity acting on the CH-CH group of donors flavin adenine dinucleotide binding electron carrier activity oxidoreductase activity acting on the CH-CH group of donors heme binding metal ion binding succinate dehydrogenase activity succinate dehydrogenase (ubiquinone) activity
1ochA malonamidase e2	[pdb]	2.16 0.00533	169^LYS 170^PRO 330^GLY 392^ARG 395^ASN 369^GLY	0.0.0.0			carbon-nitrogen ligase activity
3e5zA putative gluconolactonase	[pdb]	2.16 0.00547	173^LYS 174^PRO 88^GLY 90^ARG 115^ASN 136^GLY	0.0.0.0
2vkrD zinc-containing ferredoxin	[pdb]	2.16 0.00547	101^LYS 102^PRO 23^GLY 7^ARG 5^ASN 39^GLY	0.0.0.0	transport electron transport chain		zinc ion binding electron carrier activity metal ion binding iron-sulfur cluster binding 3 iron 4 sulfur cluster binding
3aaeB f-actin-capping protein subunit alpha-1 f-actin-capping protein subunit beta isoforms 1 and 2 32mer peptide from leucine-rich repeat-containing protein16a	[pdb]	2.16 0.00547	78^LYS 74^PRO 68^GLY 66^ARG 65^ASN 86^GLY		actin cytoskeleton organization actin filament capping cell projection organization lamellipodium assembly actin cytoskeleton organization actin filament capping	cytoplasm F-actin capping protein complex Z disc WASH complex cytoplasm cytoskeleton F-actin capping protein complex membrane lamellipodium cortical cytoskeleton cytoplasm	actin binding actin binding
3k50A putative s41 protease	[pdb]	2.16 0.00547	220^LYS 197^PRO 325^GLY 324^ARG 256^ASN 259^GLY	0.0.0.0	proteolysis		protein binding serine-type peptidase activity
1jj7A peptide transporter tap1	[pdb]	2.16 0.00548	606^LYS 607^PRO 592^GLY 593^ARG 598^ASN 602^GLY	0.0.0.0	transport defense response protein transport peptide transport intracellular transport of viral proteins in host cell antigen processing and presentation of endogenous peptide antigen via MHC class I protection from natural killer cell mediated cytotoxicity interspecies interaction between organisms cytosol to ER transport transmembrane transport	mitochondrion endoplasmic reticulum endoplasmic reticulum membrane microsome cytosol membrane integral to membrane integral to endoplasmic reticulum membrane TAP complex	nucleotide binding transporter activity protein binding ATP binding peptide transporter activity ATPase activity nucleoside-triphosphatase activity peptide antigen binding ATPase activity coupled to transmembrane movement of substances protein homodimerization activity ADP binding TAP1 binding TAP2 binding
2dhfA dihydrofolate reductase	[pdb]	2.16 0.00562	108^LYS 103^PRO 69^GLY 70^ARG 48^ASN 45^GLY	1.5.1.3	glycine biosynthetic process one-carbon metabolic process nucleotide biosynthetic process response to methotrexate tetrahydrofolate metabolic process oxidation-reduction process	cellular_component	dihydrofolate reductase activity drug binding oxidoreductase activity NADP binding
1sj2B peroxidase/catalase t	[pdb]	2.17 0.00562	590^LYS 589^PRO 676^GLY 693^ARG 596^ASN 599^GLY	1.11.1.7, 1.11.1.6	response to oxidative stress hydrogen peroxide catabolic process response to antibiotic oxidation-reduction process		catalase activity peroxidase activity oxidoreductase activity heme binding metal ion binding
1sevA malate dehydrogenase, glyoxysomal precursor	[pdb]	2.17 0.00562	184^LYS 183^PRO 288^GLY 316^ARG 317^ASN 318^GLY	1.1.1.37	carbohydrate metabolic process glycolysis glyoxylate cycle tricarboxylic acid cycle malate metabolic process metabolic process cellular carbohydrate metabolic process oxidation-reduction process	peroxisome glyoxysome	catalytic activity binding oxidoreductase activity malate dehydrogenase activity oxidoreductase activity acting on the CH-OH group of donors
2dkvA chitinase	[pdb]	2.17 0.00562	252^LYS 253^PRO 292^GLY 327^ARG 330^ASN 287^GLY	0.0.0.0	polysaccharide catabolic process carbohydrate metabolic process chitin catabolic process defense response metabolic process cell wall macromolecule catabolic process defense response to fungus		chitinase activity chitin binding hydrolase activity hydrolase activity
1s8iA phospholipase a2 homolog	[pdb]	2.17 0.00578	38^LYS 37^PRO 32^GLY 34^ARG 28^ASN 26^GLY	0.0.0.0	phospholipid metabolic process pathogenesis lipid catabolic process	extracellular region	phospholipase A2 activity calcium ion binding
1iaxA 1-aminocyclopropane-1-carboxylate synthase 2	[pdb]	2.17 0.00578	278^LYS 283^PRO 340^GLY 338^ARG 56^ASN 363^GLY	4.4.1.14	biosynthetic process ethylene biosynthetic process ripening		catalytic activity transferase activity transferring nitrogenous groups lyase activity 1-aminocyclopropane-1-carboxylate synthase activity
1efhB hydroxysteroid sulfotransferase	[pdb]	2.17 0.00578	44^LYS 43^PRO 252^GLY 124^ARG 122^ASN 249^GLY	2.8.2.14	lipid metabolic process digestion steroid metabolic process bile acid catabolic process sulfation	cytoplasm cytosol	sulfotransferase activity transferase activity bile-salt sulfotransferase activity
3hjeA 704aa long hypothetical glycosyltransferase	[pdb]	2.17 0.00578	644^LYS 645^PRO 430^GLY 428^ARG 425^ASN 658^GLY	0.0.0.0	carbohydrate metabolic process		catalytic activity transferase activity cation binding
1xtzA ribose-5-phosphate isomerase	[pdb]	2.18 0.00593	151^LYS 150^PRO 160^GLY 158^ARG 156^ASN 154^GLY	5.3.1.6	pentose-phosphate shunt pyridoxine biosynthetic process pentose-phosphate shunt	nucleus cytoplasm	ribose-5-phosphate isomerase activity protein binding isomerase activity identical protein binding
2iukA seed lipoxygenase	[pdb]	2.18 0.00593	257^LYS 221^PRO 566^GLY 569^ARG 574^ASN 259^GLY	1.13.11.12	fatty acid biosynthetic process lipid biosynthetic process oxylipin biosynthetic process oxidation-reduction process	cytoplasm	iron ion binding lipoxygenase activity oxidoreductase activity oxidoreductase activity acting on single donors with incorporation of molecular oxygen
3ngbI envelope glycoprotein gp160 antigen binding fragment of light chain antigen binding fragment of heavy chain	[pdb]	2.18 0.00609	252^LYS 253^PRO 235^GLY 480^ARG 478^ASN 263^GLY		apoptosis evasion by virus of host immune response interspecies interaction between organisms	plasma membrane membrane integral to membrane virion viral envelope host cell plasma membrane host cell membrane host cell endosome	structural molecule activity
1uliE biphenyl dioxygenase large subunit biphenyl dioxygenase small subunit	[pdb]	2.18 0.00609	67^GLU 66^ARG 128^HIS 92^LEU 88^MET 69^ALA	0.0.0.0	cellular aromatic compound metabolic process aromatic compound catabolic process oxidation-reduction process cellular aromatic compound metabolic process oxidation-reduction process		iron ion binding oxidoreductase activity oxidoreductase activity acting on single donors with incorporation of molecular oxygen incorporation of two atoms of oxygen oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen NADH or NADPH as one donor and incorporation of two atoms of oxygen into one donor
3i99A udp-n-acetylenolpyruvoylglucosamine reductase	[pdb]	2.18 0.00609	62^LYS 21^PRO 99^GLY 80^ARG 79^ASN 126^GLY	1.1.1.158	cellular cell wall organization cell cycle regulation of cell shape peptidoglycan biosynthetic process cell division oxidation-reduction process cellular cell wall organization cell cycle regulation of cell shape peptidoglycan biosynthetic process cell division oxidation-reduction process	cytoplasm cytoplasm	catalytic activity UDP-N-acetylmuramate dehydrogenase activity oxidoreductase activity flavin adenine dinucleotide binding catalytic activity UDP-N-acetylmuramate dehydrogenase activity oxidoreductase activity flavin adenine dinucleotide binding
2ptaA pandinus toxin k-alpha	[pdb]	2.19 0.00609	18^LYS 15^PRO 37^GLY 38^ARG 25^ASN 22^GLY	0.0.0.0	pathogenesis	extracellular region	ion channel inhibitor activity potassium channel inhibitor activity
1jwaB molybdopterin [mpt] converting factor, subunit 1 molybdopterin biosynthesis moeb protein	[pdb]	2.19 0.00609	86^LYS 85^PRO 198^GLY 73^ALA 70^ASP 43^ALA	0.0.0.0	Mo-molybdopterin cofactor biosynthetic process metabolic process Mo-molybdopterin cofactor biosynthetic process sulfur compound metabolic process		nucleotide binding catalytic activity binding protein binding ATP binding transferase activity nucleotidyltransferase activity metal ion binding nucleotide binding protein binding
2x50B trypanothione reductase	[pdb]	2.19 0.00626	189^LYS 188^PRO 246^GLY 248^ARG 208^ASN 215^GLY	0.0.0.0	cell redox homeostasis oxidation-reduction process	cytoplasm	disulfide oxidoreductase activity trypanothione-disulfide reductase activity oxidoreductase activity flavin adenine dinucleotide binding
1y6iA mg-chelatase cofactor gun4	[pdb]	2.19 0.00626	194^LYS 193^PRO 215^GLY 214^ARG 211^ASN 186^GLY	0.0.0.0			binding
1mioC nitrogenase molybdenum iron protein (alphachain) nitrogenase molybdenum iron protein (beta chain)	[pdb]	2.19 0.00626	67^SER 93^SER 86^THR 88^VAL 102^VAL 64^ALA	1.18.6.1	nitrogen fixation oxidation-reduction process nitrogen fixation oxidation-reduction process	molybdenum-iron nitrogenase complex molybdenum-iron nitrogenase complex	nucleotide binding ATP binding nitrogenase activity oxidoreductase activity metal ion binding iron-sulfur cluster binding nucleotide binding ATP binding nitrogenase activity oxidoreductase activity metal ion binding iron-sulfur cluster binding
3me5A cytosine-specific methyltransferase	[pdb]	2.19 0.00626	455^LYS 454^PRO 251^GLY 288^ARG 291^ASN 285^GLY	0.0.0.0	DNA methylation DNA restriction-modification system		DNA binding DNA (cytosine-5-)-methyltransferase activity methyltransferase activity transferase activity
3cnoA putative uncharacterized protein	[pdb]	2.19 0.00626	112^LYS 152^PRO 84^GLY 87^ARG 117^ASN 111^GLY	0.0.0.0		intracellular	GTP binding